Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3898571..3898716 Replicon chromosome
Accession NZ_CP029587
Organism Klebsiella pneumoniae strain DA33141

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3898607..3898709 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3898571..3898716 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ66_RS19455 3893701..3895761 + 2061 WP_004151449.1 oligopeptidase B -
DLJ66_RS19460 3895765..3896424 - 660 WP_002911407.1 exodeoxyribonuclease X -
DLJ66_RS19465 3896503..3896733 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DLJ66_RS19470 3896846..3897220 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DLJ66_RS19475 3897224..3898093 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
DLJ66_RS19480 3898110..3898448 + 339 WP_009307539.1 YebY family protein -
- 3898571..3898716 - 146 - - Antitoxin
- 3898607..3898709 + 103 - - Toxin
DLJ66_RS28640 3899085..3899228 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DLJ66_RS19490 3899333..3900301 - 969 WP_004151446.1 VirK/YbjX family protein -
DLJ66_RS19495 3900458..3901111 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
DLJ66_RS19500 3901108..3901299 - 192 WP_002911395.1 YebW family protein -
DLJ66_RS19505 3901397..3901636 - 240 WP_002911393.1 YebV family protein -
DLJ66_RS19510 3901752..3903185 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T105939 NZ_CP029587:3898607-3898709 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT105939 NZ_CP029587:c3898716-3898571 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References