Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 789780..790038 Replicon chromosome
Accession NZ_CP029327
Organism Escherichia coli strain A37

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag AOY90_RS03655 Protein ID WP_000809168.1
Coordinates 789780..789932 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 789981..790038 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY90_RS03635 785024..785737 - 714 WP_001102393.1 acidic protein MsyB -
AOY90_RS03640 785763..786167 - 405 WP_097752027.1 DUF2541 family protein -
AOY90_RS03645 786540..788456 + 1917 WP_000516135.1 molecular chaperone DnaK -
AOY90_RS03650 788545..789675 + 1131 WP_001118464.1 molecular chaperone DnaJ -
AOY90_RS03655 789780..789932 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 789981..790038 + 58 - - Antitoxin
AOY90_RS03660 790547..791308 + 762 WP_001274832.1 outer membrane protein OmpK -
AOY90_RS03665 791329..792822 + 1494 WP_001591496.1 sulfatase-like hydrolase/transferase -
AOY90_RS03670 792951..794210 + 1260 WP_000494928.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T105409 WP_000809168.1 NZ_CP029327:c789932-789780 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T105409 NZ_CP029327:c789932-789780 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT105409 NZ_CP029327:789981-790038 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References