Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2190751..2191223 Replicon chromosome
Accession NZ_CP028949
Organism Serratia marcescens strain AR_0121

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AM368_RS10530 Protein ID WP_033649650.1
Coordinates 2190751..2191026 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AM368_RS10535 Protein ID WP_033649649.1
Coordinates 2191026..2191223 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM368_RS10515 2185795..2186172 - 378 WP_033649652.1 AprI/Inh family metalloprotease inhibitor -
AM368_RS10520 2186228..2187691 - 1464 WP_033636674.1 serralysin family metalloprotease -
AM368_RS10525 2188373..2190691 + 2319 WP_048321227.1 zinc/cadmium/mercury/lead-transporting ATPase -
AM368_RS10530 2190751..2191026 - 276 WP_033649650.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AM368_RS10535 2191026..2191223 - 198 WP_033649649.1 hypothetical protein Antitoxin
AM368_RS10540 2191285..2191530 - 246 WP_025304890.1 sulfurtransferase TusA -
AM368_RS10545 2191751..2192410 + 660 WP_033649648.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
AM368_RS10550 2192452..2192886 + 435 WP_033649647.1 GNAT family N-acetyltransferase -
AM368_RS10555 2192967..2193530 + 564 WP_033636670.1 DcrB family lipoprotein -
AM368_RS10560 2193566..2194765 - 1200 WP_033636667.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
AM368_RS10565 2194762..2196030 - 1269 WP_043148323.1 glycerol-3-phosphate dehydrogenase subunit GlpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10638.51 Da        Isoelectric Point: 11.2806

>T104464 WP_033649650.1 NZ_CP028949:c2191026-2190751 [Serratia marcescens]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVIPAGRHPRIFRRGRVDGTHEIPLHPHYLLVYQVLETHIRA
LRVLHTRRQYP

Download         Length: 276 bp

>T104464 NZ_CP028949:c2191026-2190751 [Serratia marcescens]
ATGCTCAACATCGAATGGACTCGAGCCGCACGTCAGGATCTGGCGGAGATTGTGGGATTCATCGCCAATGATAACCCTCT
GGCGGCCAGAAAAATGAAGGTTCTCATCATGGAGGCCGTCATTCCCGCCGGCAGACATCCTCGAATTTTCCGGCGCGGCA
GAGTGGACGGCACGCATGAAATCCCCCTACATCCCCATTATCTCCTGGTTTACCAGGTGCTGGAAACTCACATCCGGGCG
TTGCGGGTTTTACATACGCGCCGACAATATCCTTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT104464 WP_033649649.1 NZ_CP028949:c2191223-2191026 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT104464 NZ_CP028949:c2191223-2191026 [Serratia marcescens]
ATGAGTATTTTACTACTGCCTACGGTTGCCAAGATGGAAAATGAGGAACGTACACAGGGCTATGAGCGCTGGTTTCTTGA
AAGAGTTCAGGAAGCCATGGATGAGCCGCGGCCCGGCATTCCTCATGATGACGTGATGGCTGAAATGGATGCTGTTATCG
CTGCTGCAGAAGCCAGGATCAAAGCGAAGCAGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References