Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1634159..1634694 Replicon chromosome
Accession NZ_CP028946
Organism Serratia marcescens strain AR_0124

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AM371_RS07680 Protein ID WP_033649525.1
Coordinates 1634419..1634694 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AM371_RS07675 Protein ID WP_085286583.1
Coordinates 1634159..1634419 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM371_RS07655 1629478..1630128 + 651 WP_085286586.1 DcrB-related protein -
AM371_RS07660 1630169..1630774 + 606 WP_060452988.1 glutathione S-transferase -
AM371_RS07665 1630844..1632238 + 1395 WP_085286585.1 L-seryl-tRNA(Sec) selenium transferase -
AM371_RS07670 1632235..1634076 + 1842 WP_085286584.1 selenocysteine-specific translation elongation factor -
AM371_RS07675 1634159..1634419 + 261 WP_085286583.1 ribbon-helix-helix domain-containing protein Antitoxin
AM371_RS07680 1634419..1634694 + 276 WP_033649525.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AM371_RS07685 1634706..1635617 - 912 WP_033636572.1 LysR family transcriptional regulator -
AM371_RS07690 1635739..1636365 + 627 WP_033649524.1 LysE family translocator -
AM371_RS07695 1636419..1637666 - 1248 WP_033649577.1 MFS transporter -
AM371_RS07700 1637884..1638876 + 993 WP_033649523.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10596.34 Da        Isoelectric Point: 10.3377

>T104418 WP_033649525.1 NZ_CP028946:1634419-1634694 [Serratia marcescens]
MELKWTSKALSDLARLFEFLALVNRTAAANSVKALVAAPKALLDNSRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T104418 NZ_CP028946:1634419-1634694 [Serratia marcescens]
ATGGAGTTAAAATGGACGAGTAAGGCGCTATCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGTTAACCGTACTGC
GGCAGCGAATTCGGTGAAGGCCTTGGTCGCCGCGCCTAAAGCGTTGCTTGATAATTCTCGCCTGGGTGAAAGACTGGACG
AGTTTTTACCGCAGGAAGTGAGGCGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9712.03 Da        Isoelectric Point: 4.5201

>AT104418 WP_085286583.1 NZ_CP028946:1634159-1634419 [Serratia marcescens]
MNTKVITAHIPLPLAEKVDEMAAKLERSRGWIVKQALTAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDD
PLPVPR

Download         Length: 261 bp

>AT104418 NZ_CP028946:1634159-1634419 [Serratia marcescens]
ATGAATACGAAAGTCATCACCGCTCATATCCCGCTGCCTTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGAACG
CTCACGGGGATGGATAGTGAAGCAAGCCCTCACCGCCTGGCTCGAGCAAGAGGAAGAGCGCCGTCGGTTAACGCTGGCGG
CGCTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAATCGGTAGAAGCCTGGGCTGCCAGCCTGGACAGTGACGAT
CCGCTGCCGGTACCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References