Detailed information of TA system TA104406

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 497397..497986
• Replicon: chromosome
• Accession: NZ_CP028941
• Organism: Polynucleobacter sp. LimPoW16

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: DCO16_RS02605
• Protein ID: WP_173942217.1
• Coordinates: 497603..497986 (+)
• Length: 128 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: DCO16_RS02600
• Protein ID: WP_173942216.1
• Coordinates: 497397..497603 (+)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DCO16_RS02590	493624..496194	+	2571	WP_173942214.1	cyanophycin synthetase	-
DCO16_RS02595	496211..497221	-	1011	WP_173942215.1	class 1 fructose-bisphosphatase	-
DCO16_RS02600	497397..497603	+	207	WP_173942216.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
DCO16_RS02605	497603..497986	+	384	WP_173942217.1	type II toxin-antitoxin system VapC family toxin	Toxin
DCO16_RS02610	497996..500626	-	2631	WP_173942218.1	aminopeptidase N	-
DCO16_RS02615	500659..501183	-	525	WP_173943740.1	TMEM165/GDT1 family protein	-
DCO16_RS02620	501359..502477	-	1119	WP_173942219.1	alanine dehydrogenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-115)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 128 a.a.
• Molecular weight: 14132.46 Da
• Isoelectric Point: 6.3175

>T104406 WP_173942217.1 NZ_CP028941:497603-497986 [Polynucleobacter sp. LimPoW16]
MTMVLADTSVWIAHFRKANPSLQSLLINDQILCHPLVLVELSCGSPPSPRVKTLDQLKCLRQATVATPDEVMAFVEKHQF
YESGCGAIDVSLLASTLLSKHALIWTFDKKLEALARQLDIAYEESIH

Nucleotide

• Length: 384 bp

>T104406 NZ_CP028941:497603-497986 [Polynucleobacter sp. LimPoW16]
ATGACGATGGTGTTAGCCGATACCTCGGTATGGATTGCTCATTTCAGAAAAGCCAATCCATCACTGCAATCCCTCTTAAT
TAATGATCAAATTCTCTGCCATCCACTGGTCTTGGTAGAGCTCTCTTGTGGATCCCCGCCCTCCCCCAGAGTCAAAACTT
TAGATCAGCTGAAATGCTTACGTCAGGCAACAGTAGCGACTCCAGATGAAGTAATGGCATTTGTAGAAAAGCATCAGTTT
TATGAATCAGGTTGTGGAGCCATAGATGTCTCTTTGCTCGCCTCAACGCTGCTATCAAAACATGCCCTCATTTGGACTTT
TGATAAAAAGCTAGAGGCACTCGCTAGGCAACTGGATATTGCTTATGAAGAGAGCATTCACTAA

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7643.89 Da
• Isoelectric Point: 10.4516

>AT104406 WP_173942216.1 NZ_CP028941:497397-497603 [Polynucleobacter sp. LimPoW16]
MRTTVTIDDDLYQRGLELAEPGMDKSELFREAMTVFVRVQIAKRLAALGGAAPNMKSIPRRRSKHEGL

Nucleotide

• Length: 207 bp

>AT104406 NZ_CP028941:497397-497603 [Polynucleobacter sp. LimPoW16]
ATGAGAACGACTGTAACGATAGATGACGATCTTTACCAAAGAGGCTTAGAGCTTGCAGAGCCGGGGATGGATAAATCCGA
GCTGTTTCGGGAGGCAATGACTGTTTTTGTCAGAGTGCAGATCGCAAAACGCTTAGCAGCTCTGGGTGGTGCAGCCCCTA
ATATGAAAAGCATCCCTCGCCGTAGATCTAAGCATGAGGGGCTTTAA