Detailed information of TA system TA104354

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2472456..2473363
• Replicon: chromosome
• Accession: NZ_CP028897
• Organism: Dongshaea marina strain DM2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DB847_RS11880
• Protein ID: WP_108650885.1
• Coordinates: 2472899..2473363 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: DB847_RS11875
• Protein ID: WP_108650883.1
• Coordinates: 2472456..2472902 (+)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DB847_RS11850	2468121..2468504	+	384	WP_108650876.1	hypothetical protein	-
DB847_RS11855	2468748..2469620	+	873	WP_108650877.1	flagellar motor stator protein MotA	-
DB847_RS11860	2469617..2470414	+	798	WP_108650879.1	OmpA family protein	-
DB847_RS11865	2470696..2471346	+	651	WP_159084569.1	transporter substrate-binding domain-containing protein	-
DB847_RS11870	2471376..2472359	+	984	WP_159084570.1	sugar ABC transporter	-
DB847_RS11875	2472456..2472902	+	447	WP_108650883.1	DUF2384 domain-containing protein	Antitoxin
DB847_RS11880	2472899..2473363	+	465	WP_108650885.1	RES domain-containing protein	Toxin
DB847_RS11885	2473376..2473708	-	333	WP_108650887.1	DUF2158 domain-containing protein	-
DB847_RS11890	2474081..2474926	-	846	WP_108650889.1	hypothetical protein	-
DB847_RS11895	2475548..2476207	-	660	WP_159084571.1	RES family NAD+ phosphorylase	-
DB847_RS11900	2476224..2476601	-	378	WP_199911813.1	MbcA/ParS/Xre antitoxin family protein	-
DB847_RS11905	2477054..2477338	+	285	WP_108650892.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-138)

Antitoxin

• Antitoxin Xre (16-148)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17124.53 Da
• Isoelectric Point: 4.5292

>T104354 WP_108650885.1 NZ_CP028897:2472899-2473363 [Dongshaea marina]
VKGYRIVKSEYLSSAWSGYGAELYGGRWNSKGHKAVYCATSISLAMLEILVHINSEALLNDYVLLEIELTEDDVMGLHSS
DLPTSWNAEPATEETQELGDEWLQSQLSVALLVPSVVVPQEMNLLLNPLHPEFTGIIQKAARLPVLFDRRLKGN

Nucleotide

• Length: 465 bp

>T104354 NZ_CP028897:2472899-2473363 [Dongshaea marina]
GTGAAGGGCTACCGAATCGTTAAATCTGAATACCTCTCCAGTGCCTGGAGTGGTTACGGCGCCGAGCTGTACGGTGGCCG
CTGGAACAGTAAGGGACATAAGGCGGTTTACTGCGCGACCTCGATCTCACTGGCGATGCTGGAGATCCTGGTGCATATCA
ACAGTGAGGCGTTGCTCAACGATTATGTCCTGCTTGAGATAGAGCTTACCGAAGATGATGTGATGGGACTGCACAGCAGT
GATCTGCCGACAAGCTGGAATGCCGAGCCCGCCACAGAGGAGACCCAGGAGCTCGGCGATGAATGGTTACAAAGTCAGTT
GTCAGTCGCCCTGCTGGTTCCCTCGGTGGTAGTTCCCCAGGAGATGAACCTGTTACTCAACCCTCTGCACCCAGAGTTTA
CCGGGATTATTCAAAAAGCCGCTCGCCTGCCGGTTCTGTTTGATCGCCGGTTAAAGGGAAATTAG

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16562.27 Da
• Isoelectric Point: 9.7454

>AT104354 WP_108650883.1 NZ_CP028897:2472456-2472902 [Dongshaea marina]
MQKRTFIPSKAVIPRLWRDVGLPAGHGLKLVMTINDGLSCDVLDRLSEAVGEPKEAIYKMTQLSKRTLARRLEQGVLKPD
ESDRVVRFIRVFDRATELFNGDRALAMNWLKEPARALGGKTPVELMTSESGAIEVFDLIGRIEHGVFS

Nucleotide

• Length: 447 bp

>AT104354 NZ_CP028897:2472456-2472902 [Dongshaea marina]
ATGCAAAAACGCACCTTTATTCCCAGTAAAGCGGTTATCCCACGGCTGTGGCGTGACGTCGGCCTTCCTGCCGGTCACGG
GCTGAAGCTGGTGATGACCATCAATGACGGGCTGTCCTGTGATGTTCTGGATCGATTAAGTGAGGCCGTTGGGGAGCCTA
AAGAAGCCATCTACAAGATGACCCAACTGAGCAAAAGAACCCTGGCCCGCCGCCTGGAGCAGGGAGTGCTCAAGCCCGAT
GAGAGCGATCGTGTGGTGCGCTTTATCCGGGTTTTTGATCGGGCCACTGAACTATTTAACGGCGATCGGGCCCTGGCGAT
GAACTGGCTCAAAGAACCCGCACGAGCCCTGGGTGGTAAAACTCCGGTTGAACTGATGACCAGCGAGTCTGGTGCAATCG
AGGTTTTTGATCTCATCGGACGCATTGAGCATGGTGTGTTCTCGTGA