Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2042729..2043000 Replicon chromosome
Accession NZ_CP028741
Organism Escherichia coli strain A34

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2042859..2042962 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2042729..2043000 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY87_RS10055 2039284..2039946 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY87_RS10060 2039970..2040626 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
AOY87_RS10065 2040728..2040958 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY87_RS10070 2041097..2041471 + 375 WP_000168738.1 CopC domain-containing protein YobA -
AOY87_RS10075 2041475..2042347 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
AOY87_RS10080 2042360..2042701 + 342 WP_000976472.1 YebY family protein -
- 2042729..2043000 - 272 - - Antitoxin
- 2042859..2042962 + 104 - - Toxin
AOY87_RS10085 2043097..2043753 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
AOY87_RS10090 2043754..2043945 - 192 WP_001313035.1 YebW family protein -
AOY87_RS10095 2044050..2044286 - 237 WP_001295499.1 YebV family protein -
AOY87_RS10100 2044404..2045843 - 1440 WP_240766057.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103309 NZ_CP028741:2042859-2042962 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103309 NZ_CP028741:c2043000-2042729 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References