Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246249..2246520 Replicon chromosome
Accession NZ_CP028656
Organism Escherichia coli strain 121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246379..2246482 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246249..2246520 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E50_RS11490 2242804..2243466 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E50_RS11495 2243490..2244146 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E50_RS11500 2244248..2244478 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E50_RS11505 2244617..2244991 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E50_RS11510 2244995..2245867 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E50_RS11515 2245880..2246221 + 342 WP_000976483.1 YebY family protein -
- 2246249..2246520 - 272 - - Antitoxin
- 2246379..2246482 + 104 - - Toxin
C9E50_RS11520 2246617..2247273 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E50_RS11525 2247274..2247465 - 192 WP_001296140.1 YebW family protein -
C9E50_RS11530 2247570..2247806 - 237 WP_001295499.1 DUF1480 family protein -
C9E50_RS11535 2247924..2249363 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102361 NZ_CP028656:2246379-2246482 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102361 NZ_CP028656:c2246520-2246249 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References