Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2195233..2195504 Replicon chromosome
Accession NZ_CP028654
Organism Escherichia coli strain 122

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2195363..2195466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2195233..2195504 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E51_RS11105 2191788..2192450 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E51_RS11110 2192474..2193130 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E51_RS11115 2193232..2193462 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E51_RS11120 2193601..2193975 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E51_RS11125 2193979..2194851 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E51_RS11130 2194864..2195205 + 342 WP_000976483.1 YebY family protein -
- 2195233..2195504 - 272 - - Antitoxin
- 2195363..2195466 + 104 - - Toxin
C9E51_RS11135 2195601..2196257 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E51_RS11140 2196258..2196449 - 192 WP_001296140.1 YebW family protein -
C9E51_RS11145 2196554..2196790 - 237 WP_001295499.1 DUF1480 family protein -
C9E51_RS11150 2196908..2198347 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102329 NZ_CP028654:2195363-2195466 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102329 NZ_CP028654:c2195504-2195233 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References