Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246108..2246379 Replicon chromosome
Accession NZ_CP028635
Organism Escherichia coli strain 134

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246238..2246341 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246108..2246379 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E58_RS11485 2242663..2243325 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E58_RS11490 2243349..2244005 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E58_RS11495 2244107..2244337 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E58_RS11500 2244476..2244850 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E58_RS11505 2244854..2245726 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E58_RS11510 2245739..2246080 + 342 WP_000976483.1 YebY family protein -
- 2246108..2246379 - 272 - - Antitoxin
- 2246238..2246341 + 104 - - Toxin
C9E58_RS11515 2246476..2247132 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E58_RS11520 2247133..2247324 - 192 WP_001296140.1 YebW family protein -
C9E58_RS11525 2247429..2247665 - 237 WP_001295499.1 DUF1480 family protein -
C9E58_RS11530 2247783..2249222 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102084 NZ_CP028635:2246238-2246341 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102084 NZ_CP028635:c2246379-2246108 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References