Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1324252..1324486 | Replicon | chromosome |
| Accession | NZ_CP028112 | ||
| Organism | Escherichia coli O103 str. RM8385 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1324382..1324485 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1324252..1324486 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I3Q_RS06860 | 1320807..1321469 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| I3Q_RS06865 | 1321493..1322149 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| I3Q_RS06870 | 1322251..1322481 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I3Q_RS06875 | 1322620..1322994 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| I3Q_RS06880 | 1322998..1323870 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| I3Q_RS06885 | 1323883..1324224 | + | 342 | WP_000976492.1 | YebY family protein | - |
| - | 1324252..1324486 | - | 235 | - | - | Antitoxin |
| - | 1324382..1324485 | + | 104 | - | - | Toxin |
| I3Q_RS06890 | 1324617..1325693 | - | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| I3Q_RS06895 | 1325659..1325940 | - | 282 | WP_001443927.1 | excisionase | - |
| I3Q_RS06900 | 1326047..1326235 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1326051..1326229 | + | 179 | NuclAT_1 | - | - |
| - | 1326051..1326229 | + | 179 | NuclAT_1 | - | - |
| - | 1326051..1326229 | + | 179 | NuclAT_1 | - | - |
| - | 1326051..1326229 | + | 179 | NuclAT_1 | - | - |
| I3Q_RS06905 | 1326228..1326422 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| I3Q_RS06910 | 1326479..1327288 | - | 810 | WP_000166317.1 | recombination protein RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 1318750..1395539 | 76789 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T100491 NZ_CP028112:1324382-1324485 [Escherichia coli O103 str. RM8385]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT100491 NZ_CP028112:c1324486-1324252 [Escherichia coli O103 str. RM8385]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
