Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6206042..6206631 Replicon chromosome
Accession NZ_CP027741
Organism Pseudomonas chlororaphis subsp. aurantiaca strain 449

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K22_RS28000 Protein ID WP_124335614.1
Coordinates 6206332..6206631 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K22_RS27995 Protein ID WP_124335613.1
Coordinates 6206042..6206335 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K22_RS27975 6201386..6202576 - 1191 WP_124300601.1 serine hydrolase -
C4K22_RS27980 6202703..6203590 + 888 WP_124335612.1 LysR family transcriptional regulator -
C4K22_RS27985 6203773..6204570 - 798 WP_081359643.1 helix-turn-helix transcriptional regulator -
C4K22_RS27990 6204750..6205670 + 921 WP_124335841.1 EamA family transporter -
C4K22_RS27995 6206042..6206335 - 294 WP_124335613.1 putative addiction module antidote protein Antitoxin
C4K22_RS28000 6206332..6206631 - 300 WP_124335614.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K22_RS28005 6206802..6207251 + 450 WP_124335615.1 DUF3828 domain-containing protein -
C4K22_RS28010 6207276..6208286 - 1011 WP_206427059.1 zinc-binding dehydrogenase -
C4K22_RS28015 6208344..6208643 - 300 WP_081359638.1 ArsR family transcriptional regulator -
C4K22_RS28020 6208707..6209798 - 1092 WP_081359637.1 nitrite reductase, copper-containing -
C4K22_RS28025 6210024..6210266 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K22_RS28030 6210263..6211150 + 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11234.09 Da        Isoelectric Point: 10.1871

>T100122 WP_124335614.1 NZ_CP027741:c6206631-6206332 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQIATFMEWENRLKDPRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQPCGLQLVILLCGGDKS
RQGRDIELAKYLARRWSRS

Download         Length: 300 bp

>T100122 NZ_CP027741:c6206631-6206332 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGATCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATCCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCCGTGCGGCCTGCAACTCGTCATCCTGTTATGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10455.00 Da        Isoelectric Point: 5.6642

>AT100122 WP_124335613.1 NZ_CP027741:c6206335-6206042 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAP

Download         Length: 294 bp

>AT100122 NZ_CP027741:c6206335-6206042 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCACGGGGCGCCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References