Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4452333..4452987 Replicon chromosome
Accession NZ_CP027741
Organism Pseudomonas chlororaphis subsp. aurantiaca strain 449

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K22_RS19885 Protein ID WP_124335830.1
Coordinates 4452333..4452683 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4K22_RS19890 Protein ID WP_124335173.1
Coordinates 4452673..4452987 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K22_RS19875 4449082..4450614 + 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -
C4K22_RS19880 4450622..4452085 + 1464 WP_009044594.1 NADH-quinone oxidoreductase subunit NuoN -
C4K22_RS19885 4452333..4452683 + 351 WP_124335830.1 toxin Toxin
C4K22_RS19890 4452673..4452987 + 315 WP_124335173.1 transcriptional regulator Antitoxin
C4K22_RS19895 4453168..4454910 - 1743 WP_038577823.1 ABC transporter substrate-binding protein -
C4K22_RS19900 4454961..4455233 - 273 WP_038577821.1 DUF2160 domain-containing protein -
C4K22_RS19905 4455244..4456044 - 801 WP_038577819.1 carbohydrate ABC transporter permease -
C4K22_RS19910 4456056..4456922 - 867 WP_038577816.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13760.74 Da        Isoelectric Point: 8.5033

>T100121 WP_124335830.1 NZ_CP027741:4452333-4452683 [Pseudomonas chlororaphis subsp. aurantiaca]
MDALFIELPPFQRHRQDYLDDELFLSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T100121 NZ_CP027741:4452333-4452683 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGGACGCACTTTTCATTGAGTTACCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCTTAGCTT
GCAGCTTGAATTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACCGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTGAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11863.76 Da        Isoelectric Point: 10.7886

>AT100121 WP_124335173.1 NZ_CP027741:4452673-4452987 [Pseudomonas chlororaphis subsp. aurantiaca]
MKRDIFSELAEGFDALAKERQGKLTLRTHKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT100121 NZ_CP027741:4452673-4452987 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAAACGTGACATCTTTTCCGAACTGGCCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCCACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCCGAAGAAGTGCTGGCCGTGCGCGAGCAGCTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGAACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACCACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References