TAfinder detailed results

Overview

Job ID 9mizKMmBqU
Sequence name Escherichia coli strain DH5alpha chromosome, complete genome.
Predicted type II

Toxin (Protein)


Predicted family itaT (T4502) Predicted domain COG2153 (ElaA)
Locus tag C1467_RS18620 Length 180 a.a.
Coordinates 3577945..3578487 (+)

Antitoxin (Protein)


Predicted family itaR (AT4502) Predicted domain COG4453 (DUF1778)
Locus tag C1467_RS18615 Length 103 a.a.
Coordinates 3577650..3577961 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS18590 3572670..3573617 + 948 WP_001239440.1 cytochrome o ubiquinol oxidase subunit II -
C1467_RS18595 3573639..3575630 + 1992 WP_000467180.1 cytochrome o ubiquinol oxidase subunit I -
C1467_RS18600 3575620..3576234 + 615 WP_000179819.1 cytochrome o ubiquinol oxidase subunit III -
C1467_RS18605 3576234..3576563 + 330 WP_000019869.1 cytochrome o ubiquinol oxidase subunit IV -
C1467_RS18610 3576575..3577465 + 891 WP_000971336.1 heme o synthase -
C1467_RS18615 3577650..3577961 + 312 WP_001297137.1 DUF1778 domain-containing protein Antitoxin
C1467_RS18620 3577945..3578487 + 543 WP_000227784.1 GNAT family N-acetyltransferase Toxin
C1467_RS18625 3578543..3579467 - 924 Protein_3432 tetratricopeptide repeat protein -
C1467_RS18630 3579875..3581239 + 1365 WP_001000978.1 MFS transporter -
C1467_RS18635 3581367..3581858 - 492 WP_001138904.1 nucleotide binding protein YajQ -
C1467_RS18640 3582026..3582937 + 912 WP_000705849.1 2-dehydropantoate 2-reductase -

Domains

The domains were predicted by HMMER and were sorted by score.

Toxin

COG2153 (ElaA) (E-value: 3e-05, Score:21.9)

(56-136)

PF00583 (GNAT) (E-value: 8.9e-05, Score:20)

(96-160)

PRK10314 (E-value: 0.0012, Score:16.7)

(69-133)

COG3818 (GNAT) (E-value: 0.0056, Score:14.6)

(92-146)

PTZ00330 (E-value: 0.041, Score:11.8)

(91-138)

Antitoxin

COG4453 (DUF1778) (E-value: 3.6e-17, Score:60.6)

(69-150)

PF08681 (DUF1778) (E-value: 3.3e-13, Score:47.6)

(8-91)

PF01402 (RHH) (E-value: 0.0079, Score:14.4)

(9-48)


Sequences

Toxin        


Download         Length: 180 a.a.        Molecular weight: 19805.02 Da        Isoelectric Point: 8.3395

>WP_000227784.1 TA_28 Toxin
MVDKHEEITLPIVLSCNYQSDITYPGQKQFDCGNPVIDKFVRASLKKSVRNSDCAAKALI
DRQSGELIGICTFTAYSLEKQRVSGVLQGSQPSEIGVVRLVMLGVARKYQKRGFGQDLLC
DFFEHVKIIHQALPIKGVYLDADPAAINFYARLGFVQLSATPNAFGAVPMFLAIQHILAA
*

Download         Length: 543 bp

>WP_000227784.1 TA_28 Toxin
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCT
GATATTACTTATCCTGGGCAAAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTT
GTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACTGTGCGGCTAAAGCACTTATT
GACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTA
GTCATGTTGGGGGTAGCACGGAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGT
GATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTACCAATTAAAGGGGTTTATCTT
GATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCT
TAG

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11358.04 Da        Isoelectric Point: 10.4825

>WP_001297137.1 TA_28 Antitoxin
MPGKTATLPDVDKTLKNARVELKTSPDAKNKLREAAQAVGVDLSAFILSAAMERAESVLD
NQRRRELSNQSWELMNQLIAEPAQPTLALKALMKRKNSDGRQA*

Download         Length: 312 bp

>WP_001297137.1 TA_28 Antitoxin
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTC
GAACTCAAAACTAGTCCCGACGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGG
GTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAACGCGCCGAAAGTGTGCTTGAT
AACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGT
CGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
AT4502 Escherichia coli HS

100

100

0.99
AT10120 Klebsiella pneumoniae subsp. pneumoniae HS11286

35.802

92.045

0.279
AT200 Escherichia coli O157:H7 str. EDL933

32.099

92.045

0.25
AT10041 Mycobacterium tuberculosis H37Rv

33.333

36.076

0.183
AT176 Vibrio cholerae O1 biovar El Tor str. N16961

28.571

62.222

0.154
AT165 Vibrio cholerae O1 biovar El Tor str. N16961

28.571

62.222

0.154