TAfinder detailed results

Overview

Job ID 9mizKMmBqU
Sequence name Escherichia coli strain DH5alpha chromosome, complete genome.
Predicted type II

Toxin (Protein)


Predicted family vapC (T439) Predicted domain PRK13725 (VapC)
Locus tag C1467_RS06865 Length 132 a.a.
Coordinates 1329386..1329784 (+)

Antitoxin (Protein)


Predicted family vapB (AT439) Predicted domain COG4456 (VagC)
Locus tag C1467_RS06860 Length 75 a.a.
Coordinates 1329159..1329386 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS06835 1324961..1325431 - 471 WP_001068682.1 thioredoxin-dependent thiol peroxidase -
C1467_RS06840 1325431..1326003 - 573 WP_000176187.1 glycine cleavage system transcriptional repressor -
C1467_RS06845 1326149..1327027 + 879 WP_001295469.1 4-hydroxy-tetrahydrodipicolinate synthase -
C1467_RS06850 1327044..1328078 + 1035 WP_001297320.1 outer membrane protein assembly factor BamC -
C1467_RS06855 1328291..1329004 + 714 WP_001295467.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
C1467_RS06860 1329159..1329386 + 228 WP_000450524.1 toxin-antitoxin system antitoxin VapB Antitoxin
C1467_RS06865 1329386..1329784 + 399 WP_000911329.1 type II toxin-antitoxin system VapC family toxin Toxin
C1467_RS06870 1329931..1330794 + 864 WP_001267498.1 neutral zinc metallopeptidase -
C1467_RS06875 1330809..1332824 + 2016 WP_000829294.1 tRNA cytosine(34) acetyltransferase TmcA -
C1467_RS06880 1332898..1333596 + 699 WP_000679823.1 esterase -
C1467_RS06885 1333677..1333877 - 201 WP_000383836.1 YpfN family protein -

Domains

The domains were predicted by HMMER and were sorted by score.

Toxin

PRK13725 (VapC) (E-value: 3.6e-79, Score:261.4)

(1-131)

cd09881 (VapC) (E-value: 2.7e-18, Score:64.3)

(2-121)

COG1487 (VapC) (E-value: 2.5e-09, Score:35.4)

(6-130)

cd09875 (VapC) (E-value: 9.7e-07, Score:27.2)

(5-122)

PF01850 (PIN) (E-value: 0.00075, Score:17.6)

(4-112)

cd09886 (NGN_SP) (E-value: 0.0015, Score:16.7)

(3-107)

cd09861 (VapC) (E-value: 0.0015, Score:16.7)

(3-107)

cd09872 (PIN_Sll0205-like) (E-value: 0.014, Score:13.5)

(2-114)

COG5573 (PIN) (E-value: 0.023, Score:12.6)

(5-94)

Antitoxin

COG4456 (VagC) (E-value: 1.9e-26, Score:90)

(4-79)

PF04014 (MazE) (E-value: 2.5e-08, Score:32.3)

(5-77)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14924.23 Da        Isoelectric Point: 8.5325

>WP_000911329.1 TA_13 Toxin
MLKFMLDTNICIFTIKNKPVHVRERFNLNSGRMCISSVTLMELIYGAEKSQMPERNLAVI
EGFVSRLEVLDYDSAAATHTGQIRAELARQGRPVGPFDQMIAGHARSRGLIVVTNNTREF
ERVAGIRLEDWS*

Download         Length: 399 bp

>WP_000911329.1 TA_13 Toxin
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTA
CATGTCAGAGAGCGGTTTAACCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTG
ATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAGAACGCAATTTGGCGGTGATT
GAAGGTTTCGTATCTCGTTTGGAAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATG
ATAGCGGGACATGCTCGCAGTCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTT
GAGCGAGTGGCGGGAATCAGACTAGAAGATTGGAGCTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8498.61 Da        Isoelectric Point: 4.3867

>WP_000450524.1 TA_13 Antitoxin
METTVFLSNRSQAVRLPKAVALPEDVKKVEIIAIGRTRIITPAGESWDSWFDGENVSADF
MDIRDQPAMQERESF*

Download         Length: 228 bp

>WP_000450524.1 TA_13 Antitoxin
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTC
GCTCTGCCAGAGGATGTTAAGAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATC
ACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCGAAAATGTGAGTGCGGATTTT
ATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.