TAfinder detailed results

Overview

Job ID 9mizKMmBqU
Sequence name Escherichia coli strain DH5alpha chromosome, complete genome.
Predicted type II

Toxin (Protein)


Predicted family mazF (T10130) Predicted domain PRK09907
Locus tag C1467_RS05360 Length 111 a.a.
Coordinates 1035053..1035388 (+)

Antitoxin (Protein)


Predicted family mazE (AT10130) Predicted domain PRK09798 (MazE)
Locus tag C1467_RS05355 Length 82 a.a.
Coordinates 1034805..1035053 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS05345 1031144..1032445 + 1302 WP_000046790.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
C1467_RS05350 1032493..1034727 + 2235 WP_000226815.1 GTP pyrophosphokinase -
C1467_RS05355 1034805..1035053 + 249 WP_000581937.1 type II toxin-antitoxin system antitoxin MazE Antitoxin
C1467_RS05360 1035053..1035388 + 336 WP_000254738.1 endoribonuclease MazF Toxin
C1467_RS05365 1035459..1036250 + 792 WP_001071648.1 nucleoside triphosphate pyrophosphohydrolase -
C1467_RS05370 1036478..1038115 + 1638 WP_000210878.1 CTP synthase (glutamine hydrolyzing) -
C1467_RS05375 1038203..1039501 + 1299 WP_000036723.1 phosphopyruvate hydratase -

Domains

The domains were predicted by HMMER and were sorted by score.

Toxin

PRK09907 (E-value: 1.9e-66, Score:219)

(1-111)

COG2337 (MazF) (E-value: 1.4e-17, Score:61.9)

(2-106)

PRK09812 (E-value: 1.8e-15, Score:55.1)

(1-108)

PF02452 (PemK) (E-value: 2.7e-06, Score:25.8)

(4-107)

Antitoxin

PRK09798 (MazE) (E-value: 1.8e-59, Score:196)

(1-82)

COG2336 (MazE) (E-value: 6.5e-34, Score:114.4)

(1-82)

smart00966 (AbrB) (E-value: 1.8e-21, Score:74.1)

(4-85)

PRK11347 (ChpS) (E-value: 4e-09, Score:34.6)

(4-83)

COG4456 (VagC) (E-value: 2.5e-08, Score:31.9)

(4-73)

TIGR02609 (doc) (E-value: 4.6e-06, Score:24.7)

(3-51)

TIGR01439 (AbrB) (E-value: 0.015, Score:13.2)

(12-52)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12098.04 Da        Isoelectric Point: 8.2618

>WP_000254738.1 TA_11 Toxin
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG*

Download         Length: 336 bp

>WP_000254738.1 TA_11 Toxin
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACA
AAAGGTAGCGAGCAAGCTGGACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAAC
AACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGCAATCAAAAGGATATCCGTTC
GAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAA
CTCATTAAAGCCAAAATTAACGTACTGATTGGGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9355.74 Da        Isoelectric Point: 4.4665

>WP_000581937.1 TA_11 Antitoxin
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVN
DITPENLHENIDWGEPKDKEVW*

Download         Length: 249 bp

>WP_000581937.1 TA_11 Antitoxin
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACG
TTAATGCAGGCGCTCAATCTGAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGC
AAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTACGCTTGCTGAACTGGTCAAC
GACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
T10130 Escherichia coli str. K-12 substr. MC4100 strain K-12

100

100

0.991
T1044 Escherichia coli str. K-12 substr. MG1655

100

100

0.991
T137 Deinococcus radiodurans R1

45.536

95.726

0.455
T10069 Klebsiella pneumoniae subsp. pneumoniae MGH 78578

44.545

98.214

0.437
T10090 Enterococcus faecalis ATCC 29212

32.955

77.876

0.259
T663 Streptococcus mutans UA159

29.703

91.818

0.268
T10067 Agrobacterium tumefaciens str. C58

38.947

79.832

0.33
T1852 Lactobacillus salivarius UCC118

30.928

85.088

0.268
T6120 Xylella fastidiosa

36.364

91.667

0.321
T6238 Lactobacillus rhamnosus ATCC 8530

34.884

74.783

0.268
T6142 Lactobacillus rhamnosus ATCC 8530

34.884

74.783

0.268
T6137 Lactobacillus rhamnosus Lc 705

34.884

74.783

0.268
T1049 Escherichia coli str. K-12 substr. MG1655

38.835

88.793

0.357
T10042 Candidatus Desulforudis audaxviator MP104C

37.736

89.831

0.357
T6252 Mycobacterium tuberculosis H37Rv

40.964

70.339

0.304
T911 Nitrosomonas europaea ATCC 19718

29.268

72.566

0.214
T1076 Shigella flexneri 2b

30.682

66.165

0.241
T6091 Staphylococcus aureus

28.261

82.143

0.232
T6141 Lactobacillus rhamnosus ATCC 8530

30.769

61.417

0.214
T6140 Lactobacillus rhamnosus GG

30.769

61.417

0.214
T6136 Lactobacillus rhamnosus Lc 705

30.769

61.417

0.214
T6135 Lactobacillus rhamnosus GG

30.769

61.417

0.214
T10131 Legionella pneumophila subsp. pneumophila str. Lorraine

26.596

88.679

0.223
T134 Bacillus subtilis subsp. subtilis str. 168

32.051

67.241

0.223
T1499 Bacillus anthracis str. Sterne

32.051

67.241

0.223
T10096 Clostridium difficile R20291

30.769

61.417

0.214
T10094 Staphylococcus aureus strain HG003 isolate RN1 Scaffold_3

25.641

65

0.179
T10078 Staphylococcus aureus strain HG003 isolate RN1 Scaffold_3

25.641

65

0.179
T1073 Staphylococcus aureus subsp. aureus N315

25.641

65

0.179
T612 Staphylococcus aureus subsp. aureus MW2

25.641

65

0.179
T6090 Staphylococcus equorum

22.222

90

0.214
T10177 Staphylococcus epidermidis isolate BPH0662

25.641

65

0.179
T101 Mycobacterium tuberculosis H37Rv

33.898

54.128

0.179
T10160 Mycobacterium tuberculosis H37Rv

32.877

68.868

0.214
T6248 Mycobacterium tuberculosis H37Rv

26.364

80.882

0.259
T6247 Mycobacterium tuberculosis H37Rv

35.484

27.193

0.098