MGE detailed information
MGE type: Conjugative plasmid MGE length: 139312 bp
Accession: NZ_LR890335 Location: 1..139312 Organism: Escherichia coli isolate MINF_9A-sc-2280436 Replicon: plasmid 2
Accession: NZ_LR890335 Location: 1..139312 Organism: Escherichia coli isolate MINF_9A-sc-2280436 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW07_RS24695 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| JMW07_RS24700 () | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| JMW07_RS24705 () | 2124..2306 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| JMW07_RS24710 () | 2649..2956 | - | 308 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| JMW07_RS24715 () | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| JMW07_RS24720 () | 4651..4779 | + | 129 | Protein_5 | IS481 family transposase | - |
| JMW07_RS24725 () | 4814..5107 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| JMW07_RS24730 () | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| JMW07_RS24735 () | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| JMW07_RS24740 () | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| JMW07_RS24745 () | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| JMW07_RS24750 () | 8173..8553 | - | 381 | Protein_11 | RidA family protein | - |
| JMW07_RS24755 () | 8578..9468 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| JMW07_RS24760 () | 9701..9895 | - | 195 | WP_000796505.1 | hypothetical protein | - |
| JMW07_RS24765 () | 9869..10309 | + | 441 | Protein_14 | zinc-binding dehydrogenase | - |
| JMW07_RS24770 () | 10440..11318 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| JMW07_RS24775 () | 11308..12195 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| JMW07_RS24780 () | 12206..13030 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| JMW07_RS24785 () | 13036..14109 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| JMW07_RS24790 () | 14102..15412 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| JMW07_RS24795 () | 15471..15779 | - | 309 | Protein_20 | IS4 family transposase ISEc13 | Transposase |
| JMW07_RS24800 () | 15856..16089 | - | 234 | Protein_21 | Tn3 family transposase ISPsy39 | Transposase |
| JMW07_RS24805 () | 16111..17307 | - | 1197 | Protein_22 | IS3 family transposase | - |
| JMW07_RS24810 () | 17332..18036 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| JMW07_RS24815 () | 18094..18624 | - | 531 | Protein_24 | histidine-type phosphatase | - |
| JMW07_RS24820 () | 18746..19231 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| JMW07_RS24825 () | 19256..19741 | - | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| JMW07_RS24830 () | 19728..20423 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| JMW07_RS24835 () | 20428..21558 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| JMW07_RS24840 () | 21548..22831 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| JMW07_RS24845 () | 22834..24213 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| JMW07_RS24850 () | 24317..24844 | - | 528 | WP_000178050.1 | iron transporter | - |
| JMW07_RS24855 () | 24885..26771 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| JMW07_RS24860 () | 27118..27933 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| JMW07_RS24865 () | 28116..28622 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| JMW07_RS24870 () | 28612..28770 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| JMW07_RS24875 () | 28920..29033 | - | 114 | Protein_36 | IS6 family transposase IS15DI | Transposase |
| JMW07_RS24880 () | 29233..29930 | + | 698 | Protein_37 | IS1 family transposase IS1X2 | Transposase |
| JMW07_RS24885 () | 29945..30163 | + | 219 | Protein_38 | IS4 family transposase | - |
| JMW07_RS24890 () | 30213..30917 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JMW07_RS24895 () | 30976..31725 | - | 750 | Protein_40 | IS91 family transposase ISAzo26 | Transposase |
| JMW07_RS24900 () | 31883..32356 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| JMW07_RS24905 () | 32487..33275 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| JMW07_RS24910 () | 33481..33828 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| JMW07_RS24915 () | 33822..34661 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| JMW07_RS24920 () | 34789..34992 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| JMW07_RS24925 () | 35148..36353 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| JMW07_RS24930 () | 36364..36669 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| JMW07_RS24935 () | 36713..36778 | + | 66 | Protein_48 | EAL domain-containing protein | - |
| JMW07_RS24940 () | 36896..37660 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| JMW07_RS24945 () | 38153..38737 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| JMW07_RS24950 () | 38737..39975 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| JMW07_RS24955 () | 39972..40877 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| JMW07_RS24960 () | 40999..41703 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JMW07_RS24965 () | 41764..41940 | + | 177 | Protein_54 | replication protein C | - |
| JMW07_RS24970 () | 42248..43063 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| JMW07_RS24975 () | 43124..43927 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| JMW07_RS24980 () | 43927..44763 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| JMW07_RS24985 () | 44817..45053 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| JMW07_RS24990 () | 45085..45711 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| JMW07_RS24995 () | 45817..47016 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| JMW07_RS25000 () | 47048..47908 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| JMW07_RS25005 () | 47917..48423 | - | 507 | Protein_62 | transposase | - |
| JMW07_RS25010 () | 48476..49180 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JMW07_RS25015 () | 49280..49552 | + | 273 | Protein_64 | DUF4158 domain-containing protein | - |
| JMW07_RS25020 () | 49620..50717 | - | 1098 | Protein_65 | TonB-dependent receptor | - |
| JMW07_RS25025 () | 50774..51742 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| JMW07_RS25030 () | 51777..52652 | - | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| JMW07_RS25035 () | 52902..53081 | - | 180 | Protein_68 | IS1380 family transposase | - |
| JMW07_RS25040 () | 53146..53850 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JMW07_RS25045 () | 53916..54461 | + | 546 | Protein_70 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JMW07_RS25050 () | 54497..54912 | - | 416 | Protein_71 | IS1 family transposase | - |
| JMW07_RS25055 () | 55161..55562 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JMW07_RS25060 () | 55495..55752 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JMW07_RS25065 () | 55845..56498 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JMW07_RS25070 () | 56596..56736 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| JMW07_RS25075 () | 57438..58295 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| JMW07_RS25080 () | 58288..58362 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| JMW07_RS25085 () | 58359..58493 | - | 135 | Protein_78 | protein CopA/IncA | - |
| JMW07_RS25090 () | 58599..58751 | - | 153 | WP_072258247.1 | replication protein A | - |
| JMW07_RS25095 () | 58832..59854 | + | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| JMW07_RS25100 () | 59851..60633 | + | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| JMW07_RS25105 () | 60702..60812 | - | 111 | Protein_82 | replication protein | - |
| JMW07_RS25110 () | 61109..61243 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 61288..61348 | + | 61 | NuclAT_2 | - | - |
| - () | 61288..61348 | + | 61 | NuclAT_2 | - | - |
| - () | 61288..61348 | + | 61 | NuclAT_2 | - | - |
| - () | 61288..61348 | + | 61 | NuclAT_2 | - | - |
| JMW07_RS25115 () | 61315..61601 | - | 287 | Protein_84 | DUF2726 domain-containing protein | - |
| JMW07_RS25120 () | 62114..62326 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| JMW07_RS25125 () | 62457..63017 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JMW07_RS25130 () | 63072..63818 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| JMW07_RS25135 () | 63838..69108 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| JMW07_RS25140 () | 69108..71288 | - | 2181 | WP_016238500.1 | type IV conjugative transfer system coupling protein TraD | - |
| JMW07_RS25145 () | 71285..72064 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| JMW07_RS25150 () | 72267..72998 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| JMW07_RS25155 () | 73030..73527 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| JMW07_RS25160 () | 73546..76365 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JMW07_RS25165 () | 76362..77735 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| JMW07_RS25170 () | 77722..78147 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| JMW07_RS25175 () | 78095..78442 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| JMW07_RS25180 () | 78372..78917 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JMW07_RS25185 () | 78904..79188 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JMW07_RS25190 () | 79315..79635 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| JMW07_RS25195 () | 79683..80380 | - | 698 | Protein_100 | IS1 family transposase IS1G | Transposase |
| JMW07_RS25200 () | 80440..80520 | - | 81 | Protein_101 | type IV conjugative transfer system protein TraL | - |
| JMW07_RS25205 () | 80525..80887 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| JMW07_RS25210 () | 80921..81148 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| JMW07_RS25215 () | 81236..81913 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| JMW07_RS25220 () | 82047..82430 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| JMW07_RS25225 () | 82761..83363 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| JMW07_RS25230 () | 83660..84481 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| JMW07_RS25235 () | 84600..84887 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| JMW07_RS25240 () | 84912..85118 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| JMW07_RS25245 () | 85031..85366 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| JMW07_RS25250 () | 85359..85514 | - | 156 | WP_001380190.1 | hypothetical protein | - |
| JMW07_RS25255 () | 85809..85967 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 86011..86138 | - | 128 | NuclAT_0 | - | - |
| - () | 86011..86138 | - | 128 | NuclAT_0 | - | - |
| - () | 86011..86138 | - | 128 | NuclAT_0 | - | - |
| - () | 86011..86138 | - | 128 | NuclAT_0 | - | - |
| - () | 87580..87682 | - | 103 | NuclAT_1 | - | - |
| - () | 87580..87682 | - | 103 | NuclAT_1 | - | - |
| - () | 87580..87682 | - | 103 | NuclAT_1 | - | - |
| - () | 87580..87682 | - | 103 | NuclAT_1 | - | - |
| JMW07_RS25265 () | 87694..88413 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| JMW07_RS25270 () | 88410..88844 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| JMW07_RS25275 () | 88899..90857 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| JMW07_RS25280 () | 90923..91156 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| JMW07_RS25285 () | 91219..91758 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| JMW07_RS25290 () | 91903..92238 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| JMW07_RS25295 () | 92231..92494 | - | 264 | WP_071781663.1 | hypothetical protein | - |
| JMW07_RS25300 () | 92401..92619 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| JMW07_RS25305 () | 92645..93208 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| JMW07_RS25310 () | 93256..94617 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| JMW07_RS25315 () | 94669..94899 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| JMW07_RS25320 () | 95566..95796 | - | 231 | Protein_125 | hypothetical protein | - |
| JMW07_RS25325 () | 95935..96126 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| JMW07_RS25330 () | 96123..96545 | - | 423 | WP_001763816.1 | DUF1380 family protein | - |
| JMW07_RS25335 () | 96592..96894 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| JMW07_RS25340 () | 97434..98210 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| JMW07_RS25345 () | 98261..98695 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| JMW07_RS25350 () | 98709..98930 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| JMW07_RS25355 () | 98931..99614 | - | 684 | WP_000086185.1 | DNA methylase | - |
| JMW07_RS25360 () | 99691..99995 | - | 305 | Protein_133 | hypothetical protein | - |
| JMW07_RS25365 () | 99999..100901 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| JMW07_RS25370 () | 101768..102739 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JMW07_RS25375 () | 102739..103905 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| JMW07_RS25380 () | 104139..104836 | + | 698 | Protein_137 | IS1 family transposase IS1S | Transposase |
| JMW07_RS25385 () | 105090..106112 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| JMW07_RS25390 () | 106097..107662 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| JMW07_RS25395 () | 107737..108153 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JMW07_RS25400 () | 108150..108380 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JMW07_RS25405 () | 108761..112555 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| JMW07_RS25410 () | 112600..113016 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JMW07_RS25415 () | 113013..113243 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JMW07_RS25420 () | 113508..114008 | + | 501 | WP_000528931.1 | hypothetical protein | - |
| JMW07_RS25425 () | 114021..114794 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| JMW07_RS25430 () | 114961..116094 | + | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| JMW07_RS25435 () | 116128..116640 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| JMW07_RS25440 () | 117207..117425 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JMW07_RS25445 () | 117427..117732 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JMW07_RS25450 () | 117733..118539 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| JMW07_RS25455 () | 119313..120068 | + | 756 | WP_024946706.1 | replication initiation protein RepE | - |
| JMW07_RS25460 () | 120502..121199 | - | 698 | Protein_153 | IS1 family transposase IS1S | Transposase |
| JMW07_RS25465 () | 121555..122469 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| JMW07_RS25470 () | 122469..123296 | + | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| JMW07_RS25475 () | 123293..124150 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| JMW07_RS25480 () | 124147..125004 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| JMW07_RS25485 () | 125238..125495 | - | 258 | Protein_158 | Tn3 family transposase | - |
| JMW07_RS25490 () | 125493..125906 | + | 414 | Protein_159 | phosphopyruvate hydratase | - |
| JMW07_RS25495 () | 126247..126627 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| JMW07_RS25500 () | 127007..128200 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| JMW07_RS25505 () | 128336..130060 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| JMW07_RS25510 () | 130061..131008 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| JMW07_RS25515 () | 131008..132750 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| JMW07_RS25520 () | 132747..134024 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| JMW07_RS25525 () | 134106..136307 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| JMW07_RS25530 () | 136687..137384 | + | 698 | Protein_167 | IS1 family transposase IS1S | Transposase |
| JMW07_RS25535 () | 137564..138077 | - | 514 | Protein_168 | DUF4113 domain-containing protein | - |
| JMW07_RS25540 () | 138138..138242 | - | 105 | Protein_169 | AAA family ATPase | - |
| JMW07_RS25545 () | 138244..138567 | - | 324 | Protein_170 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|