MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 98473 bp
Accession: NZ_LR595692 Location: 1..98473 Organism: Escherichia coli isolate EcMAD1 Replicon: plasmid pEcMAD1
Accession: NZ_LR595692 Location: 1..98473 Organism: Escherichia coli isolate EcMAD1 Replicon: plasmid pEcMAD1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECMAD3_RS23030 () | 1..135 | - | 135 | Protein_0 | TetR/AcrR family transcriptional regulator | - |
| ECMAD3_RS23035 () | 135..1373 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| ECMAD3_RS23040 () | 1370..2275 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| ECMAD3_RS23050 () | 2397..3101 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23055 () | 3138..4265 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| ECMAD3_RS23060 () | 4316..4543 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| ECMAD3_RS23065 () | 4567..4758 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| ECMAD3_RS23070 () | 5240..5782 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| ECMAD3_RS23075 () | 5795..6655 | - | 861 | WP_000557454.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| ECMAD3_RS23085 () | 6798..7760 | + | 963 | Protein_9 | IS4 family transposase IS10R | Transposase |
| ECMAD3_RS23090 () | 7870..8715 | + | 846 | Protein_10 | IS4 family transposase IS10R | Transposase |
| ECMAD3_RS23095 () | 8770..9474 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| ECMAD3_RS23100 () | 9538..9729 | + | 192 | Protein_12 | helix-turn-helix domain-containing protein | - |
| ECMAD3_RS23105 () | 9912..10772 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| ECMAD3_RS23110 () | 10919..11200 | + | 282 | Protein_14 | transposase zinc-binding domain-containing protein | - |
| ECMAD3_RS23115 () | 11359..12063 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS24170 () | 12116..12262 | - | 147 | Protein_16 | EAL domain-containing protein | - |
| ECMAD3_RS23130 () | 12465..13478 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| ECMAD3_RS23135 () | 13636..14109 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| ECMAD3_RS23140 () | 14240..15028 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| ECMAD3_RS23145 () | 15234..15581 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| ECMAD3_RS23150 () | 15575..16414 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| ECMAD3_RS23160 () | 16542..16745 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| ECMAD3_RS23165 () | 16901..17266 | + | 366 | Protein_23 | chromate transporter | - |
| ECMAD3_RS23170 () | 17320..18024 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| ECMAD3_RS23175 () | 18158..18751 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| ECMAD3_RS23180 () | 18864..20069 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| ECMAD3_RS23185 () | 20151..20774 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| ECMAD3_RS23190 () | 20752..20871 | - | 120 | Protein_28 | ArsR family transcriptional regulator | - |
| ECMAD3_RS23195 () | 20887..21584 | - | 698 | Protein_29 | IS1 family transposase IS1R | Transposase |
| ECMAD3_RS23200 () | 21626..21820 | + | 195 | WP_086258557.1 | hypothetical protein | - |
| ECMAD3_RS23205 () | 21855..21983 | - | 129 | Protein_31 | IS481 family transposase | - |
| ECMAD3_RS23210 () | 22016..23185 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| ECMAD3_RS23220 () | 23678..23985 | + | 308 | Protein_33 | type II toxin-antitoxin system ParD family antitoxin | - |
| ECMAD3_RS23230 () | 24328..24510 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| ECMAD3_RS23235 () | 24631..25371 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| ECMAD3_RS23240 () | 25656..26633 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| ECMAD3_RS23250 () | 27429..27842 | - | 414 | Protein_37 | IS3 family transposase ISLad1 | Transposase |
| ECMAD3_RS23255 () | 27766..28125 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| ECMAD3_RS23260 () | 28153..28332 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| ECMAD3_RS23265 () | 28337..28717 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| ECMAD3_RS23270 () | 28717..28938 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| ECMAD3_RS23275 () | 29121..30677 | + | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| ECMAD3_RS23280 () | 30674..31957 | + | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| ECMAD3_RS23285 () | 32079..35195 | + | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| ECMAD3_RS23290 () | 35409..36106 | + | 698 | Protein_45 | IS1 family transposase IS1G | Transposase |
| ECMAD3_RS23295 () | 36243..37175 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| ECMAD3_RS23300 () | 37179..38174 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| ECMAD3_RS23305 () | 38639..40777 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| ECMAD3_RS23310 () | 40939..41355 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECMAD3_RS23315 () | 41352..41582 | - | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECMAD3_RS23325 () | 41889..45008 | + | 3120 | WP_023909028.1 | hypothetical protein | - |
| ECMAD3_RS23330 () | 45271..46404 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| ECMAD3_RS23335 () | 46424..46708 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| ECMAD3_RS23340 () | 46705..46902 | - | 198 | WP_000215657.1 | hypothetical protein | - |
| ECMAD3_RS23345 () | 47536..47754 | + | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| ECMAD3_RS23350 () | 47756..48061 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| ECMAD3_RS23355 () | 48062..48868 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| ECMAD3_RS23360 () | 49642..50397 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| ECMAD3_RS23365 () | 50985..52151 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| ECMAD3_RS23370 () | 52151..53122 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ECMAD3_RS23385 () | 53989..54891 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| ECMAD3_RS23390 () | 54895..55199 | + | 305 | Protein_62 | hypothetical protein | - |
| ECMAD3_RS23395 () | 55276..55959 | + | 684 | WP_000086185.1 | DNA methylase | - |
| ECMAD3_RS23400 () | 55960..56181 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| ECMAD3_RS23405 () | 56195..56629 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| ECMAD3_RS23410 () | 56680..57456 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| ECMAD3_RS23420 () | 57996..58298 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| ECMAD3_RS23425 () | 58345..58767 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| ECMAD3_RS23430 () | 58764..58955 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| ECMAD3_RS23440 () | 59990..60220 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| ECMAD3_RS23445 () | 60272..61354 | + | 1083 | WP_060621339.1 | DUF3560 domain-containing protein | - |
| ECMAD3_RS23450 () | 61324..63717 | + | 2394 | Protein_72 | Multifunctional conjugation protein TraI | Relaxase |
| ECMAD3_RS23455 () | 63737..64483 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| ECMAD3_RS23460 () | 64538..65098 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| ECMAD3_RS23465 () | 65229..65441 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| ECMAD3_RS23475 () | 65954..66240 | + | 287 | Protein_76 | DUF2726 domain-containing protein | - |
| - () | 66207..66267 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66207..66267 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66207..66267 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66207..66267 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| ECMAD3_RS23480 () | 66312..66446 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| ECMAD3_RS23485 () | 66743..66997 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| ECMAD3_RS23490 () | 67157..67903 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| ECMAD3_RS23495 () | 67918..69459 | - | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| ECMAD3_RS24260 () | 69690..69824 | + | 135 | Protein_81 | protein CopA/IncA | - |
| ECMAD3_RS23505 () | 69821..69895 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| ECMAD3_RS23510 () | 69888..70745 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| ECMAD3_RS23520 () | 71685..72338 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| ECMAD3_RS23525 () | 72431..72688 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ECMAD3_RS23530 () | 72621..73022 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ECMAD3_RS23535 () | 73159..75504 | - | 2346 | Protein_87 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| ECMAD3_RS23540 () | 75567..76271 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23545 () | 76415..76969 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| ECMAD3_RS23550 () | 77100..77930 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| ECMAD3_RS23555 () | 78068..78508 | + | 441 | Protein_91 | CatB-related O-acetyltransferase | - |
| ECMAD3_RS23560 () | 78562..79266 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23565 () | 79331..81574 | - | 2244 | Protein_93 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ECMAD3_RS23570 () | 81588..81920 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| ECMAD3_RS23575 () | 81967..82842 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| ECMAD3_RS23580 () | 83224..83928 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23585 () | 83992..84330 | + | 339 | Protein_97 | Tn3 family transposase TnpR_Tn3 | Transposase |
| ECMAD3_RS23590 () | 84513..85373 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| ECMAD3_RS23595 () | 85520..87991 | - | 2472 | Protein_99 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| ECMAD3_RS23600 () | 87994..88554 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| ECMAD3_RS23605 () | 88567..88887 | + | 321 | Protein_101 | IS1380 family transposase | - |
| ECMAD3_RS23610 () | 89127..89768 | + | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| ECMAD3_RS23615 () | 89993..90664 | - | 672 | Protein_103 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| ECMAD3_RS23620 () | 90728..91432 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23630 () | 91482..92201 | + | 720 | Protein_105 | AAA family ATPase | - |
| ECMAD3_RS23635 () | 92188..93039 | + | 852 | WP_000240536.1 | replication protein | - |
| ECMAD3_RS23645 () | 93347..94162 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| ECMAD3_RS23650 () | 94223..95026 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| ECMAD3_RS23655 () | 95026..95862 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| ECMAD3_RS23660 () | 95923..96627 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECMAD3_RS23665 () | 96767..97531 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| ECMAD3_RS23680 () | 98024..98473 | - | 450 | WP_139581642.1 | TetR/AcrR family transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|