MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 108280 bp
Accession: NZ_CP123037 Location: 1..108280 Organism: Escherichia coli strain E22 Replicon: plasmid pE22P1
Accession: NZ_CP123037 Location: 1..108280 Organism: Escherichia coli strain E22 Replicon: plasmid pE22P1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEN54_RS23360 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| QEN54_RS23365 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| QEN54_RS23370 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| QEN54_RS23375 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QEN54_RS23380 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| QEN54_RS23385 (3449) | 3449..4321 | + | 873 | WP_104989445.1 | hypothetical protein | - |
| QEN54_RS23390 (4355) | 4355..5052 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| QEN54_RS23395 (5068) | 5068..5187 | + | 120 | Protein_7 | transcriptional regulator | - |
| QEN54_RS23400 (5165) | 5165..5788 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| QEN54_RS23405 (5870) | 5870..7075 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| QEN54_RS23410 (7188) | 7188..7781 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| QEN54_RS23415 (7915) | 7915..8619 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23420 (8673) | 8673..9038 | - | 366 | Protein_12 | chromate transporter | - |
| QEN54_RS23425 (9194) | 9194..9397 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| QEN54_RS23430 (9525) | 9525..10364 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| QEN54_RS23435 (10358) | 10358..10705 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| QEN54_RS23440 (10822) | 10822..11660 | - | 839 | Protein_16 | Streptomycin 3''-adenylyltransferase | ARG |
| QEN54_RS23445 (11666) | 11666..11956 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| QEN54_RS23450 (12068) | 12068..12565 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| QEN54_RS23455 (12710) | 12710..13576 | + | 867 | Protein_19 | IS91 family transposase ISAzo26 | Transposase |
| QEN54_RS23460 (13631) | 13631..14335 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QEN54_RS23465 (14399) | 14399..14737 | + | 339 | Protein_21 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QEN54_RS23470 (14920) | 14920..15780 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| QEN54_RS23475 (15927) | 15927..18398 | - | 2472 | Protein_23 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| QEN54_RS23480 (18401) | 18401..18961 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| QEN54_RS23485 (18974) | 18974..19294 | + | 321 | Protein_25 | IS1380 family transposase | - |
| QEN54_RS23490 (19534) | 19534..20175 | + | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| QEN54_RS23495 (20400) | 20400..21071 | - | 672 | Protein_27 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| QEN54_RS23500 (21135) | 21135..21839 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| QEN54_RS23505 (21889) | 21889..22608 | + | 720 | Protein_29 | helicase RepA family protein | - |
| QEN54_RS23510 (22595) | 22595..23446 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| QEN54_RS23515 (23754) | 23754..24569 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| QEN54_RS23520 (24630) | 24630..25433 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| QEN54_RS23525 (25433) | 25433..26269 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| QEN54_RS23530 (26330) | 26330..27034 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23535 (27174) | 27174..27938 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| QEN54_RS23540 (28431) | 28431..29015 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| QEN54_RS23545 (29015) | 29015..30253 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| QEN54_RS23550 (30250) | 30250..31164 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| QEN54_RS23555 (31286) | 31286..31990 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23560 (32027) | 32027..33154 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| QEN54_RS23565 (33205) | 33205..33432 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| QEN54_RS23570 (33456) | 33456..33647 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| QEN54_RS23575 (34129) | 34129..34671 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| QEN54_RS23580 (34684) | 34684..35544 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| QEN54_RS23585 (35687) | 35687..36649 | + | 963 | Protein_45 | IS4 family transposase IS10R | Transposase |
| QEN54_RS23590 (36759) | 36759..37604 | + | 846 | Protein_46 | IS4 family transposase IS10R | Transposase |
| QEN54_RS23595 (37659) | 37659..38363 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QEN54_RS23600 (38427) | 38427..38618 | + | 192 | Protein_48 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QEN54_RS23605 (38801) | 38801..39661 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| QEN54_RS23610 (39808) | 39808..40089 | + | 282 | Protein_50 | transposase zinc-binding domain-containing protein | - |
| QEN54_RS23615 (40248) | 40248..40952 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23620 (40843) | 40843..41151 | - | 309 | Protein_52 | EAL domain-containing protein | - |
| QEN54_RS23625 (41354) | 41354..42367 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| QEN54_RS23630 (42525) | 42525..42998 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| QEN54_RS23635 (43129) | 43129..43917 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| QEN54_RS23640 (44123) | 44123..44470 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| QEN54_RS23645 (44464) | 44464..45303 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| QEN54_RS23650 (45708) | 45708..47249 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| QEN54_RS23655 (47562) | 47562..47936 | + | 375 | Protein_59 | protein-disulfide reductase DsbD family protein | - |
| QEN54_RS23660 (48036) | 48036..48593 | + | 558 | Protein_60 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| QEN54_RS23665 (48604) | 48604..49242 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| QEN54_RS23670 (49247) | 49247..49612 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| QEN54_RS23675 (49616) | 49616..50428 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| QEN54_RS23680 (50529) | 50529..50822 | - | 294 | Protein_64 | IS30 family transposase ISAba125 | Transposase |
| QEN54_RS23685 (50987) | 50987..51691 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23690 (51746) | 51746..51817 | + | 72 | Protein_66 | hypothetical protein | - |
| QEN54_RS23695 (52073) | 52073..52948 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| QEN54_RS23700 (52995) | 52995..53288 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| QEN54_RS23705 (53353) | 53353..55572 | + | 2220 | Protein_69 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QEN54_RS23710 (55649) | 55649..56353 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23715 (56407) | 56407..56847 | - | 441 | Protein_71 | CatB-related O-acetyltransferase | - |
| QEN54_RS23720 (56985) | 56985..57815 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| QEN54_RS23725 (57946) | 57946..58500 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| QEN54_RS23730 (58644) | 58644..59348 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QEN54_RS23735 (59420) | 59420..61756 | + | 2337 | Protein_75 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| QEN54_RS23740 (61893) | 61893..62294 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| QEN54_RS23745 (62227) | 62227..62484 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| QEN54_RS23750 (62577) | 62577..63230 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| QEN54_RS23755 (64170) | 64170..65027 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| QEN54_RS23760 (65020) | 65020..65094 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| QEN54_RS23765 (65456) | 65456..66997 | + | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| QEN54_RS23770 (67012) | 67012..67758 | + | 747 | WP_053906593.1 | IS21 family transposase ISEc12 | Transposase |
| QEN54_RS23775 (67918) | 67918..68172 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| QEN54_RS23780 (68469) | 68469..68603 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (68648) | 68648..68708 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (68648) | 68648..68708 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (68648) | 68648..68708 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (68648) | 68648..68708 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| QEN54_RS23785 (68675) | 68675..68961 | - | 287 | Protein_85 | DUF2726 domain-containing protein | - |
| QEN54_RS23790 (69474) | 69474..69686 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| QEN54_RS23795 (69817) | 69817..70377 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| QEN54_RS23800 (70432) | 70432..71178 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| QEN54_RS23805 (71198) | 71198..73591 | - | 2394 | Protein_89 | Multifunctional conjugation protein TraI | Relaxase |
| QEN54_RS23810 (73585) | 73585..74643 | - | 1059 | Protein_90 | DUF3560 domain-containing protein | - |
| QEN54_RS23815 (74695) | 74695..74925 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| QEN54_RS23820 (75960) | 75960..76151 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| QEN54_RS23825 (76148) | 76148..76569 | - | 422 | Protein_93 | DUF1380 family protein | - |
| QEN54_RS23830 (76616) | 76616..77041 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| QEN54_RS23835 (77458) | 77458..78234 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| QEN54_RS23840 (78285) | 78285..78803 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| QEN54_RS23845 (78733) | 78733..78954 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| QEN54_RS23850 (78955) | 78955..79638 | - | 684 | WP_000086185.1 | DNA methylase | - |
| QEN54_RS23855 (79715) | 79715..80026 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| QEN54_RS23860 (80023) | 80023..80925 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| QEN54_RS23865 (81792) | 81792..82763 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QEN54_RS23870 (82763) | 82763..83929 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| QEN54_RS23875 (84517) | 84517..85272 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| QEN54_RS23880 (86046) | 86046..86852 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| QEN54_RS23885 (86853) | 86853..87158 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| QEN54_RS23890 (87160) | 87160..87378 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| QEN54_RS23895 (88012) | 88012..88209 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| QEN54_RS23900 (88206) | 88206..88490 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| QEN54_RS23905 (88510) | 88510..89643 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| QEN54_RS23910 (89906) | 89906..93025 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| QEN54_RS23915 (93332) | 93332..93562 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| QEN54_RS23920 (93559) | 93559..93975 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QEN54_RS23925 (94137) | 94137..96275 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| QEN54_RS23930 (96740) | 96740..97735 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| QEN54_RS23935 (97778) | 97778..98671 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| QEN54_RS23945 (99719) | 99719..102835 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| QEN54_RS23950 (102957) | 102957..104240 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| QEN54_RS23955 (104237) | 104237..105793 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| QEN54_RS23960 (105976) | 105976..106197 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| QEN54_RS23965 (106197) | 106197..106577 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| QEN54_RS23970 (106582) | 106582..106761 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| QEN54_RS23975 (106789) | 106789..107067 | + | 279 | Protein_123 | pdcB | - |
| QEN54_RS23980 (107072) | 107072..107485 | + | 414 | Protein_124 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|