MGE detailed information
MGE type: Conjugative plasmid MGE length: 130351 bp
Accession: NZ_CP119748 Location: 1..130351 Organism: Escherichia coli strain E15 Replicon: plasmid pE15-2
Accession: NZ_CP119748 Location: 1..130351 Organism: Escherichia coli strain E15 Replicon: plasmid pE15-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P1J19_RS25290 (1047) | 1047..1787 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| P1J19_RS25295 (1908) | 1908..2096 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| P1J19_RS25300 (2470) | 2470..3372 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| P1J19_RS25305 (3441) | 3441..4550 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| P1J19_RS25310 (4983) | 4983..5936 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| P1J19_RS25315 (7233) | 7233..7412 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| P1J19_RS25320 (7551) | 7551..8750 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| P1J19_RS25325 (8898) | 8898..9223 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| P1J19_RS25330 (9269) | 9269..9609 | + | 341 | Protein_9 | IS3 family transposase | - |
| P1J19_RS25335 (10204) | 10204..11391 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| P1J19_RS25340 (11388) | 11388..13328 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| P1J19_RS25345 (13332) | 13332..14702 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| P1J19_RS25350 (15176) | 15176..15370 | + | 195 | Protein_13 | IS200/IS605-like element IS200C family transposase | - |
| P1J19_RS25355 (15499) | 15499..16440 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| P1J19_RS25360 (16675) | 16675..18064 | - | 1390 | Protein_15 | ISNCY family transposase ISKpn21 | Transposase |
| P1J19_RS25365 (18374) | 18374..18523 | - | 150 | Protein_16 | IS3 family transposase IS2 | Transposase |
| P1J19_RS25370 (18701) | 18701..19894 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| P1J19_RS25375 (21136) | 21136..21873 | - | 738 | Protein_18 | IS3 family transposase IS2 | Transposase |
| P1J19_RS25380 (21926) | 21926..23088 | + | 1163 | WP_088846059.1 | IS3 family transposase ISEc17 | Transposase |
| P1J19_RS25385 (23105) | 23105..23625 | - | 521 | Protein_20 | IS3 family transposase IS2 | Transposase |
| P1J19_RS25390 (24250) | 24250..24543 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| P1J19_RS25395 (24601) | 24601..24800 | - | 200 | Protein_22 | lysis protein | - |
| P1J19_RS25400 (25354) | 25354..26378 | + | 1025 | Protein_23 | integrase core domain-containing protein | - |
| P1J19_RS25405 (27689) | 27689..28804 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| P1J19_RS25410 (28944) | 28944..32603 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| P1J19_RS25415 (32707) | 32707..33936 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| P1J19_RS25420 (34021) | 34021..34977 | + | 957 | WP_000271274.1 | hypothetical protein | VF |
| P1J19_RS25425 (35022) | 35022..37199 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| P1J19_RS25430 (38065) | 38065..39099 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| P1J19_RS25435 (39280) | 39280..39581 | + | 302 | Protein_30 | hypothetical protein | - |
| P1J19_RS25440 (39659) | 39659..39967 | - | 309 | WP_000377483.1 | DUF6404 family protein | - |
| P1J19_RS25445 (40120) | 40120..40245 | - | 126 | Protein_32 | type II toxin-antitoxin system toxin YacB | - |
| P1J19_RS25450 (40245) | 40245..40513 | - | 269 | Protein_33 | type II toxin-antitoxin system antitoxin YacA | - |
| P1J19_RS25455 (41124) | 41124..42398 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| P1J19_RS25460 (42391) | 42391..44487 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| P1J19_RS25465 (44657) | 44657..44968 | - | 312 | WP_001259758.1 | colicin V | - |
| P1J19_RS25470 (44946) | 44946..45182 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| P1J19_RS25475 (45301) | 45301..45744 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| P1J19_RS25480 (45716) | 45716..46120 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| P1J19_RS25485 (46122) | 46122..46391 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| P1J19_RS25490 (46388) | 46388..47368 | + | 981 | WP_063099985.1 | NAD(P)-binding domain-containing protein | - |
| P1J19_RS25495 (47444) | 47444..47824 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| P1J19_RS25500 (47821) | 47821..48168 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| P1J19_RS25505 (48218) | 48218..49078 | + | 861 | Protein_44 | IS66 family transposase ISEc8 | Transposase |
| P1J19_RS25510 (49114) | 49114..50412 | - | 1299 | Protein_45 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P1J19_RS25515 (50480) | 50480..51183 | + | 704 | Protein_46 | IS6 family transposase IS26 | Transposase |
| P1J19_RS25520 (51377) | 51377..51763 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| P1J19_RS25525 (52083) | 52083..52475 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| P1J19_RS25530 (52810) | 52810..53514 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P1J19_RS25535 (53834) | 53834..55009 | + | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| P1J19_RS25540 (55033) | 55033..58185 | + | 3153 | WP_000347934.1 | multidrug efflux RND transporter permease subunit OqxB3 | VF |
| P1J19_RS25545 (58255) | 58255..58734 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| P1J19_RS25550 (58836) | 58836..59540 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P1J19_RS25555 (59605) | 59605..60855 | - | 1251 | Protein_54 | transposase | - |
| P1J19_RS25560 (60930) | 60930..61598 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| P1J19_RS25565 (61634) | 61634..61870 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| P1J19_RS25570 (61867) | 61867..62229 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| P1J19_RS25575 (62247) | 62247..63941 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| P1J19_RS25580 (63993) | 63993..64415 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| P1J19_RS25585 (64451) | 64451..64726 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| P1J19_RS25590 (64740) | 64740..65090 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| P1J19_RS25595 (65162) | 65162..65596 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| P1J19_RS25605 (66649) | 66649..67050 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P1J19_RS25610 (66983) | 66983..67240 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P1J19_RS25615 (67333) | 67333..67641 | - | 309 | WP_226116723.1 | CPBP family intramembrane metalloprotease | - |
| P1J19_RS25620 (67583) | 67583..67975 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| P1J19_RS25625 (68073) | 68073..68213 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| P1J19_RS25630 (68914) | 68914..69771 | - | 858 | WP_105075777.1 | incFII family plasmid replication initiator RepA | - |
| P1J19_RS25635 (69764) | 69764..70246 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| P1J19_RS25640 (70239) | 70239..70286 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| P1J19_RS25645 (70277) | 70277..70528 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| P1J19_RS25650 (70545) | 70545..70802 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| P1J19_RS25655 (71086) | 71086..71235 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (71279) | 71279..71340 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (71279) | 71279..71340 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (71279) | 71279..71340 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (71279) | 71279..71340 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| P1J19_RS25660 (71596) | 71596..71670 | - | 75 | Protein_75 | endonuclease | - |
| P1J19_RS25665 (71916) | 71916..72128 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| P1J19_RS25670 (72264) | 72264..72824 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| P1J19_RS25675 (72927) | 72927..73787 | - | 861 | WP_000704514.1 | Quorum-quenching protein AidA | VF |
| P1J19_RS25680 (73846) | 73846..74592 | - | 747 | WP_276170845.1 | conjugal transfer pilus acetylase TraX | - |
| P1J19_RS25685 (74612) | 74612..79882 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| P1J19_RS25690 (79964) | 79964..80191 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| P1J19_RS25695 (80211) | 80211..81491 | - | 1281 | Protein_82 | type IV conjugative transfer system coupling protein TraD | - |
| P1J19_RS25700 (81744) | 81744..82475 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| P1J19_RS25705 (82507) | 82507..83004 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| P1J19_RS25710 (83020) | 83020..85842 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| P1J19_RS25715 (85839) | 85839..87212 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| P1J19_RS25720 (87212) | 87212..87592 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| P1J19_RS25725 (87579) | 87579..87920 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| P1J19_RS25730 (87850) | 87850..88395 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| P1J19_RS25735 (88382) | 88382..88666 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| P1J19_RS25740 (88747) | 88747..89061 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| P1J19_RS25745 (89063) | 89063..89410 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| P1J19_RS25750 (89426) | 89426..90169 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| P1J19_RS25755 (90162) | 90162..90419 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| P1J19_RS25760 (90446) | 90446..91654 | - | 1209 | Protein_95 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| P1J19_RS25765 (91647) | 91647..92609 | - | 963 | WP_276170843.1 | conjugal transfer pilus assembly protein TraU | - |
| P1J19_RS25770 (92606) | 92606..93238 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| P1J19_RS25775 (93235) | 93235..93621 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| P1J19_RS25780 (93618) | 93618..95855 | - | 2238 | Protein_99 | type IV secretion system protein TraC | - |
| P1J19_RS25785 (95886) | 95886..96140 | - | 255 | Protein_100 | conjugal transfer protein TraP | - |
| P1J19_RS25790 (96130) | 96130..97557 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P1J19_RS25795 (97557) | 97557..98285 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P1J19_RS25800 (98272) | 98272..98838 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| P1J19_RS25805 (98860) | 98860..99171 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| P1J19_RS25810 (99186) | 99186..99551 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| P1J19_RS25815 (99584) | 99584..99985 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| P1J19_RS25820 (100078) | 100078..100767 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| P1J19_RS25825 (100954) | 100954..101337 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P1J19_RS25830 (101658) | 101658..102260 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| P1J19_RS25835 (102557) | 102557..103378 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| P1J19_RS25840 (103496) | 103496..103783 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| P1J19_RS25845 (103808) | 103808..104014 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| P1J19_RS25850 (104084) | 104084..104256 | + | 173 | Protein_113 | hypothetical protein | - |
| P1J19_RS25855 (104254) | 104254..104484 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| P1J19_RS25860 (104704) | 104704..104829 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P1J19_RS25865 (104771) | 104771..104920 | - | 150 | Protein_116 | plasmid maintenance protein Mok | - |
| - (104906) | 104906..105130 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (104906) | 104906..105130 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (104906) | 104906..105130 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (104906) | 104906..105130 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| P1J19_RS25870 (104942) | 104942..105130 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| P1J19_RS25875 (105099) | 105099..105861 | - | 763 | Protein_118 | plasmid SOS inhibition protein A | - |
| P1J19_RS25880 (105858) | 105858..106292 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| P1J19_RS25885 (106347) | 106347..106544 | - | 198 | Protein_120 | hypothetical protein | - |
| P1J19_RS25890 (106572) | 106572..106805 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| P1J19_RS25895 (106873) | 106873..107412 | - | 540 | WP_276170844.1 | single-stranded DNA-binding protein | - |
| P1J19_RS25900 (107438) | 107438..107644 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| P1J19_RS25905 (107714) | 107714..107794 | + | 81 | Protein_124 | hypothetical protein | - |
| P1J19_RS25910 (107977) | 107977..108146 | - | 170 | Protein_125 | hypothetical protein | - |
| P1J19_RS25915 (108783) | 108783..109754 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| P1J19_RS25920 (109754) | 109754..110920 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| P1J19_RS25930 (112402) | 112402..114603 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| P1J19_RS25935 (114629) | 114629..115962 | - | 1334 | Protein_130 | L-lysine N6-monooxygenase | VF |
| P1J19_RS25940 (115959) | 115959..117701 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| P1J19_RS25945 (117701) | 117701..118648 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| P1J19_RS25950 (118649) | 118649..120373 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| P1J19_RS25955 (120509) | 120509..121702 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| P1J19_RS25960 (122082) | 122082..122462 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| P1J19_RS25965 (122803) | 122803..123216 | - | 414 | Protein_136 | phosphopyruvate hydratase | - |
| P1J19_RS25970 (123214) | 123214..123471 | + | 258 | Protein_137 | Tn3 family transposase | - |
| P1J19_RS25975 (123705) | 123705..124562 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| P1J19_RS25980 (124559) | 124559..125416 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| P1J19_RS25985 (125413) | 125413..126240 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| P1J19_RS25990 (126240) | 126240..127154 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| P1J19_RS25995 (127510) | 127510..128207 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| P1J19_RS26000 (128387) | 128387..128900 | - | 514 | Protein_143 | DUF4113 domain-containing protein | - |
| P1J19_RS26005 (128961) | 128961..129065 | - | 105 | Protein_144 | AAA family ATPase | - |
| P1J19_RS26010 (129067) | 129067..129390 | - | 324 | Protein_145 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|