MGE detailed information
MGE type: Conjugative plasmid MGE length: 140278 bp
Accession: NZ_CP117007 Location: 1..140278 Organism: Escherichia coli strain MLI109 Replicon: plasmid p140_MLI109
Accession: NZ_CP117007 Location: 1..140278 Organism: Escherichia coli strain MLI109 Replicon: plasmid p140_MLI109
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NL412_RS00005 (1) | 1..834 | + | 834 | WP_123009962.1 | incFII family plasmid replication initiator RepA | - |
| NL412_RS00010 (1825) | 1825..2835 | - | 1011 | WP_089634347.1 | IS110 family transposase IS1663 | Transposase |
| NL412_RS00015 (3041) | 3041..3622 | + | 582 | Protein_2 | 3'-5' exonuclease | - |
| NL412_RS00020 (3763) | 3763..4221 | + | 459 | WP_001236004.1 | hypothetical protein | - |
| NL412_RS00025 (4381) | 4381..4800 | + | 420 | Protein_4 | IS110 family transposase IS1618 | Transposase |
| NL412_RS00030 (5019) | 5019..5738 | - | 720 | WP_015057129.1 | FadR/GntR family transcriptional regulator | - |
| NL412_RS00035 (5829) | 5829..6920 | - | 1092 | WP_097514773.1 | L-idonate 5-dehydrogenase | - |
| NL412_RS00040 (6889) | 6889..8250 | - | 1362 | WP_097514772.1 | D-galactonate transporter | VF |
| NL412_RS00045 (8334) | 8334..9101 | - | 768 | WP_015057126.1 | 5-keto-D-gluconate 5-reductase | VF |
| NL412_RS00050 (9439) | 9439..10692 | + | 1254 | WP_097514771.1 | enolase C-terminal domain-like protein | - |
| NL412_RS00055 (10786) | 10786..11427 | - | 642 | WP_015057124.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| NL412_RS00060 (11595) | 11595..14582 | + | 2988 | WP_097514770.1 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| NL412_RS00065 (14607) | 14607..15212 | + | 606 | Protein_12 | IS110 family transposase IS1618 | Transposase |
| NL412_RS00070 (15505) | 15505..15744 | + | 240 | Protein_13 | IS4 family transposase | - |
| NL412_RS00075 (15901) | 15901..16614 | - | 714 | WP_033553771.1 | Protein SapB | VF |
| NL412_RS00080 (16678) | 16678..17697 | - | 1020 | WP_024200979.1 | nucleoside hydrolase | - |
| NL412_RS00085 (17672) | 17672..18703 | - | 1032 | WP_001402895.1 | LacI family DNA-binding transcriptional regulator | - |
| NL412_RS00090 (18809) | 18809..20203 | - | 1395 | WP_001402894.1 | MFS transporter | - |
| NL412_RS00095 (20401) | 20401..20532 | - | 132 | Protein_18 | Rpn family recombination-promoting nuclease/putative transposase | - |
| NL412_RS00100 (20805) | 20805..21185 | + | 381 | WP_255073561.1 | aspartate 1-decarboxylase | - |
| NL412_RS00105 (21192) | 21192..21371 | - | 180 | Protein_20 | polysaccharide deacetylase family protein | - |
| NL412_RS00110 (21447) | 21447..21954 | - | 508 | Protein_21 | IS3 family transposase IS2 | Transposase |
| NL412_RS00115 (22051) | 22051..23670 | + | 1620 | WP_077885511.1 | ISL3 family transposase ISEc38 | Transposase |
| NL412_RS00120 (23719) | 23719..23852 | + | 134 | Protein_23 | phosphate-starvation-inducible protein PsiE | - |
| NL412_RS00125 (23927) | 23927..25378 | - | 1452 | WP_001403463.1 | Na+/H+ antiporter NhaC | - |
| NL412_RS00130 (25371) | 25371..26549 | - | 1179 | WP_001403462.1 | MalY/PatB family protein | - |
| NL412_RS00135 (26782) | 26782..26916 | + | 135 | Protein_26 | hypothetical protein | - |
| NL412_RS00140 (27023) | 27023..27762 | + | 740 | Protein_27 | IS3 family transposase IS629 | Transposase |
| NL412_RS00145 (28274) | 28274..28396 | + | 123 | WP_001406634.1 | hypothetical protein | - |
| NL412_RS00150 (28435) | 28435..29943 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NL412_RS00155 (30027) | 30027..30152 | + | 126 | Protein_30 | IS3 family transposase | - |
| NL412_RS00160 (30188) | 30188..31401 | + | 1214 | WP_096858452.1 | IS3 family transposase ISEc31 | Transposase |
| NL412_RS00165 (31477) | 31477..32475 | - | 999 | WP_023063783.1 | Arabinose 5-phosphate isomerase KdsD | VF |
| NL412_RS00170 (32672) | 32672..33334 | + | 663 | WP_233298555.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| NL412_RS00175 (33367) | 33367..34668 | + | 1302 | WP_023063782.1 | four-carbon acid sugar kinase family protein | - |
| NL412_RS00180 (34691) | 34691..35689 | + | 999 | WP_000803224.1 | 4-hydroxythreonine-4-phosphate dehydrogenase PdxA | - |
| NL412_RS00185 (35728) | 35728..37278 | + | 1551 | WP_000127288.1 | SLC13 family permease | - |
| NL412_RS00190 (37650) | 37650..38006 | + | 357 | WP_001403398.1 | IS66 family transposase IS682 | Transposase |
| NL412_RS00195 (38055) | 38055..39269 | - | 1215 | Protein_38 | IS3 family transposase | - |
| NL412_RS00200 (39324) | 39324..39539 | + | 216 | Protein_39 | Tn3 family transposase | - |
| NL412_RS00205 (39616) | 39616..39924 | + | 309 | Protein_40 | IS4 family transposase ISEc13 | Transposase |
| NL412_RS00210 (39986) | 39986..41296 | - | 1311 | WP_044691086.1 | ABC transporter substrate-binding protein | - |
| NL412_RS00215 (41289) | 41289..42362 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| NL412_RS00220 (42368) | 42368..43192 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| NL412_RS00225 (43203) | 43203..44090 | - | 888 | WP_032250673.1 | carbohydrate ABC transporter permease | - |
| NL412_RS00230 (44080) | 44080..44958 | - | 879 | WP_162753362.1 | sugar ABC transporter permease | - |
| NL412_RS00235 (45089) | 45089..45655 | - | 567 | Protein_46 | zinc-binding dehydrogenase | - |
| NL412_RS00240 (46008) | 46008..46898 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| NL412_RS00245 (46923) | 46923..47303 | + | 381 | WP_097514827.1 | Rid family detoxifying hydrolase | - |
| NL412_RS00250 (47336) | 47336..48301 | + | 966 | WP_023063778.1 | 2-keto-3-deoxygluconate transporter | - |
| NL412_RS00255 (48347) | 48347..49099 | - | 753 | WP_001403368.1 | IclR family transcriptional regulator | - |
| NL412_RS00260 (49704) | 49704..49988 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| NL412_RS00265 (49988) | 49988..50263 | + | 276 | WP_032250674.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NL412_RS00270 (50369) | 50369..50572 | + | 204 | Protein_53 | hypothetical protein | - |
| NL412_RS00275 (50697) | 50697..50825 | - | 129 | Protein_54 | IS481 family transposase | - |
| NL412_RS00280 (50858) | 50858..52027 | - | 1170 | WP_032250676.1 | hypothetical protein | - |
| NL412_RS00285 (52559) | 52559..52827 | + | 269 | Protein_56 | type II toxin-antitoxin system ParD family antitoxin | - |
| NL412_RS00290 (52814) | 52814..53104 | + | 291 | Protein_57 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NL412_RS00295 (53171) | 53171..53353 | + | 183 | WP_050488504.1 | hypothetical protein | - |
| NL412_RS00300 (53474) | 53474..54214 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| NL412_RS00305 (54492) | 54492..55469 | - | 978 | WP_000361615.1 | RepB family plasmid replication initiator protein | - |
| NL412_RS00315 (57744) | 57744..58169 | + | 426 | WP_032278491.1 | IS66 family transposase ISEc23 | Transposase |
| NL412_RS00320 (58166) | 58166..58516 | + | 351 | WP_044807173.1 | IS66 family transposase ISEc23 | Transposase |
| NL412_RS00325 (58547) | 58547..60104 | + | 1558 | Protein_64 | IS66 family transposase ISEc23 | Transposase |
| NL412_RS00330 (60328) | 60328..62466 | + | 2139 | WP_032269946.1 | ATPase AAA | - |
| NL412_RS00335 (62636) | 62636..63037 | - | 402 | WP_001441071.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NL412_RS00340 (63061) | 63061..63291 | - | 231 | WP_001261288.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NL412_RS00345 (63885) | 63885..64103 | + | 219 | WP_167792262.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NL412_RS00350 (64105) | 64105..64410 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NL412_RS00355 (64411) | 64411..65220 | + | 810 | Protein_70 | site-specific integrase | - |
| NL412_RS00360 (65358) | 65358..65633 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| NL412_RS00365 (65627) | 65627..66271 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| NL412_RS00370 (66500) | 66500..67471 | + | 972 | WP_001103689.1 | plasmid segregation protein ParM | - |
| NL412_RS00375 (67476) | 67476..67868 | + | 393 | WP_000340832.1 | plasmid partitioning/stability family protein | - |
| NL412_RS00380 (67900) | 67900..69144 | - | 1245 | WP_000457535.1 | translesion error-prone DNA polymerase V subunit UmuC | - |
| NL412_RS00385 (69144) | 69144..69581 | - | 438 | WP_000109070.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NL412_RS00390 (69578) | 69578..69826 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NL412_RS00395 (70101) | 70101..71003 | + | 903 | WP_077513943.1 | DUF1281 domain-containing protein | - |
| NL412_RS00400 (71062) | 71062..71546 | - | 485 | Protein_79 | IS3 family transposase IS629 | Transposase |
| NL412_RS00405 (71630) | 71630..73138 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NL412_RS00410 (73177) | 73177..73299 | - | 123 | WP_001406634.1 | hypothetical protein | - |
| NL412_RS00415 (73811) | 73811..74008 | - | 198 | Protein_82 | IS3 family transposase IS629 | Transposase |
| NL412_RS00420 (74380) | 74380..75132 | + | 753 | WP_032269683.1 | Chaperone protein caf1M | VF |
| NL412_RS00425 (75187) | 75187..77736 | + | 2550 | WP_167792263.1 | F1 capsule-anchoring protein | VF |
| NL412_RS00430 (77750) | 77750..78190 | + | 441 | WP_001390764.1 | Protein AggB | VF |
| NL412_RS00435 (78365) | 78365..78880 | + | 516 | WP_255073825.1 | hypothetical protein | VF |
| NL412_RS00440 (78961) | 78961..79119 | + | 159 | Protein_87 | IS256 family transposase IS1414 | Transposase |
| NL412_RS00445 (79329) | 79329..80491 | + | 1163 | WP_085947771.1 | IS3 family transposase IS3 | Transposase |
| NL412_RS00450 (80686) | 80686..81714 | + | 1029 | WP_001403359.1 | class 1 isoprenoid biosynthesis enzyme | - |
| NL412_RS00455 (81718) | 81718..82257 | + | 540 | WP_001387337.1 | isopentenyl-diphosphate Delta-isomerase | - |
| NL412_RS00460 (82322) | 82322..82645 | + | 324 | Protein_91 | transposase | - |
| NL412_RS00465 (82760) | 82760..82912 | - | 153 | WP_000565591.1 | hypothetical protein | - |
| NL412_RS00470 (83145) | 83145..83511 | - | 367 | Protein_93 | IS3 family transposase IS1203 | Transposase |
| NL412_RS00475 (83570) | 83570..83933 | - | 364 | Protein_94 | zinc ABC transporter substrate-binding protein | - |
| NL412_RS00480 (83932) | 83932..84120 | - | 189 | Protein_95 | IS200/IS605 family transposase | - |
| NL412_RS00485 (84499) | 84499..85502 | + | 1004 | Protein_96 | IS110 family transposase ISPlu13 | Transposase |
| NL412_RS00490 (85778) | 85778..85999 | - | 222 | Protein_97 | IS1 family transposase ISEc30 | Transposase |
| NL412_RS00495 (86250) | 86250..87047 | - | 798 | WP_000769457.1 | CFA/I fimbrial subunit D | VF |
| NL412_RS00500 (87263) | 87263..87588 | - | 326 | Protein_99 | IS3 family transposase | - |
| NL412_RS00505 (87584) | 87584..87780 | + | 197 | Protein_100 | IS3 family transposase | - |
| NL412_RS00510 (87888) | 87888..88238 | - | 351 | WP_000721276.1 | hypothetical protein | VF |
| NL412_RS00515 (88548) | 88548..88863 | + | 316 | Protein_102 | hypothetical protein | - |
| NL412_RS00520 (88969) | 88969..89169 | + | 201 | WP_024210368.1 | AggR-activated transcriptional regulator Aar | - |
| NL412_RS00525 (89352) | 89352..90380 | + | 1029 | Protein_104 | IS630 family transposase | - |
| NL412_RS00530 (90697) | 90697..92422 | + | 1726 | Protein_105 | S6 family peptidase | - |
| NL412_RS00535 (92556) | 92556..92753 | - | 198 | Protein_106 | IS66 family transposase IS682 | Transposase |
| NL412_RS00540 (92914) | 92914..93084 | - | 171 | Protein_107 | IS3 family transposase IS1203 | Transposase |
| NL412_RS00545 (93464) | 93464..94594 | + | 1131 | WP_044691031.1 | dispersin export ABC transporter permease subunit AatP | - |
| NL412_RS00550 (94591) | 94591..95829 | + | 1239 | WP_044691032.1 | dispersin export ABC transporter outer membrane protein AatA | - |
| NL412_RS00555 (95726) | 95726..96547 | + | 822 | WP_033879863.1 | dispersin export-associated protein AatB | - |
| NL412_RS00560 (96540) | 96540..97169 | + | 630 | WP_000621743.1 | dispersin export ABC transporter ATP-binding protein AatC | - |
| NL412_RS00565 (97181) | 97181..98392 | + | 1212 | WP_001390768.1 | dispersin export-associated protein AatD | - |
| NL412_RS00570 (99022) | 99022..99662 | + | 641 | WP_248785200.1 | IS1 family transposase IS1X2 | Transposase |
| NL412_RS00575 (99654) | 99654..100145 | - | 492 | WP_228340195.1 | IS3 family transposase ISCARN101 | Transposase |
| NL412_RS00580 (100225) | 100225..100527 | + | 303 | Protein_115 | hypothetical protein | - |
| NL412_RS00585 (100582) | 100582..101016 | + | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| NL412_RS00590 (101013) | 101013..101775 | + | 763 | Protein_117 | plasmid SOS inhibition protein A | - |
| - (101744) | 101744..101968 | + | 225 | NuclAT_0 | - | - |
| - (101744) | 101744..101968 | + | 225 | NuclAT_0 | - | - |
| - (101744) | 101744..101968 | + | 225 | NuclAT_0 | - | - |
| - (101744) | 101744..101968 | + | 225 | NuclAT_0 | - | - |
| NL412_RS00595 (101954) | 101954..102103 | + | 150 | Protein_118 | plasmid maintenance protein Mok | - |
| NL412_RS00600 (102045) | 102045..102170 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NL412_RS00605 (102473) | 102473..102722 | - | 250 | Protein_120 | hypothetical protein | - |
| NL412_RS00610 (103023) | 103023..103310 | + | 288 | WP_000107526.1 | hypothetical protein | - |
| NL412_RS00615 (103429) | 103429..104250 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| NL412_RS00620 (104545) | 104545..105147 | - | 603 | WP_077786836.1 | hypothetical protein | VF |
| NL412_RS00625 (105478) | 105478..105861 | + | 384 | WP_023063829.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NL412_RS00630 (106055) | 106055..106747 | + | 693 | WP_001403354.1 | PAS domain-containing protein | - |
| NL412_RS00635 (106835) | 106835..107062 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| NL412_RS00640 (107096) | 107096..107458 | + | 363 | WP_044692361.1 | type IV conjugative transfer system pilin TraA | - |
| NL412_RS00645 (107463) | 107463..107774 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NL412_RS00650 (107796) | 107796..108362 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NL412_RS00655 (108349) | 108349..109077 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NL412_RS00660 (109077) | 109077..110528 | + | 1452 | WP_000146647.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NL412_RS00665 (110518) | 110518..111084 | + | 567 | WP_244588479.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NL412_RS00670 (111071) | 111071..111382 | + | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| NL412_RS00675 (111382) | 111382..111897 | + | 516 | WP_032277441.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NL412_RS00680 (112032) | 112032..112253 | + | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| NL412_RS00685 (112413) | 112413..115040 | + | 2628 | WP_097514781.1 | type IV secretion system protein TraC | - |
| NL412_RS00690 (115037) | 115037..115423 | + | 387 | WP_032277443.1 | type-F conjugative transfer system protein TrbI | - |
| NL412_RS00695 (115420) | 115420..116052 | + | 633 | WP_032277445.1 | type-F conjugative transfer system protein TraW | - |
| NL412_RS00700 (116049) | 116049..117041 | + | 993 | WP_032277446.1 | conjugal transfer pilus assembly protein TraU | - |
| NL412_RS00705 (117071) | 117071..117376 | + | 306 | WP_000224413.1 | hypothetical protein | - |
| NL412_RS00710 (117385) | 117385..118023 | + | 639 | WP_123009964.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NL412_RS00715 (118020) | 118020..119870 | + | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NL412_RS00720 (119897) | 119897..120154 | + | 258 | WP_123009963.1 | conjugal transfer protein TrbE | - |
| NL412_RS00725 (120147) | 120147..120890 | + | 744 | WP_001030370.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NL412_RS00730 (120906) | 120906..121244 | + | 339 | WP_001287901.1 | conjugal transfer protein TrbA | - |
| NL412_RS00735 (121371) | 121371..121655 | + | 285 | WP_000623730.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NL412_RS00740 (121642) | 121642..122187 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NL412_RS00745 (122117) | 122117..122464 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| NL412_RS00750 (122445) | 122445..122836 | + | 392 | Protein_149 | F-type conjugal transfer protein TrbF | - |
| NL412_RS00755 (122823) | 122823..124196 | + | 1374 | WP_001403427.1 | conjugal transfer pilus assembly protein TraH | - |
| NL412_RS00760 (124193) | 124193..127015 | + | 2823 | WP_089634351.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NL412_RS00765 (127031) | 127031..127516 | + | 486 | WP_097514778.1 | surface exclusion protein | - |
| NL412_RS00770 (127565) | 127565..128296 | + | 732 | WP_001403424.1 | conjugal transfer complement resistance protein TraT | - |
| NL412_RS00775 (128368) | 128368..128979 | + | 612 | WP_000908442.1 | hypothetical protein | - |
| NL412_RS00780 (129261) | 129261..131432 | + | 2172 | WP_097514777.1 | type IV conjugative transfer system coupling protein TraD | - |
| NL412_RS00785 (131432) | 131432..136702 | + | 5271 | WP_097514776.1 | Multifunctional conjugation protein TraI | Relaxase |
| NL412_RS00790 (136722) | 136722..137468 | + | 747 | WP_000205736.1 | conjugal transfer pilus acetylase TraX | - |
| NL412_RS00795 (137523) | 137523..138083 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| NL412_RS00800 (138215) | 138215..138427 | + | 213 | WP_072042863.1 | ANR family transcriptional regulator | - |
| NL412_RS00805 (138939) | 138939..139225 | + | 287 | Protein_160 | DUF2726 domain-containing protein | - |
| - (139192) | 139192..139243 | - | 52 | NuclAT_1 | - | - |
| - (139192) | 139192..139243 | - | 52 | NuclAT_1 | - | - |
| - (139192) | 139192..139243 | - | 52 | NuclAT_1 | - | - |
| - (139192) | 139192..139243 | - | 52 | NuclAT_1 | - | - |
| NL412_RS00810 (139289) | 139289..139423 | + | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| NL412_RS00815 (139720) | 139720..139974 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|