MGE detailed information
MGE type: Integron MGE length: 103554 bp
Accession: NZ_CP116901 Location: 1..103554 Organism: Escherichia coli strain XH2172 Replicon: plasmid pXH2172-NDM
Accession: NZ_CP116901 Location: 1..103554 Organism: Escherichia coli strain XH2172 Replicon: plasmid pXH2172-NDM
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PH219_RS23170 (392) | 392..739 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| PH219_RS23175 (733) | 733..1572 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PH219_RS23180 (1700) | 1700..1903 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| PH219_RS23185 (2059) | 2059..2532 | + | 474 | WP_252378084.1 | chromate transporter | - |
| PH219_RS23190 (2478) | 2478..3182 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23195 (3316) | 3316..3909 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| PH219_RS23200 (4022) | 4022..5227 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| PH219_RS23205 (5309) | 5309..5932 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| PH219_RS23210 (5910) | 5910..6029 | - | 120 | Protein_9 | transcriptional regulator | - |
| PH219_RS23220 (6776) | 6776..7648 | - | 873 | WP_104989445.1 | hypothetical protein | - |
| PH219_RS23225 (8180) | 8180..8448 | + | 269 | Protein_12 | type II toxin-antitoxin system ParD family antitoxin | - |
| PH219_RS23230 (8435) | 8435..8724 | + | 290 | Protein_13 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PH219_RS23235 (8791) | 8791..8973 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| PH219_RS23240 (9094) | 9094..9834 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| PH219_RS23245 (10119) | 10119..11096 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| PH219_RS23250 (11892) | 11892..12305 | - | 414 | Protein_17 | IS3 family transposase ISLad1 | Transposase |
| PH219_RS23255 (12310) | 12310..12588 | - | 279 | Protein_18 | pdcB | - |
| PH219_RS23260 (12616) | 12616..12795 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| PH219_RS23265 (12800) | 12800..13180 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| PH219_RS23270 (13180) | 13180..13401 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| PH219_RS23275 (13584) | 13584..15140 | + | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| PH219_RS23280 (15137) | 15137..16420 | + | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| PH219_RS23285 (16542) | 16542..19658 | + | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| PH219_RS23290 (19872) | 19872..20569 | + | 698 | WP_223364856.1 | IS1 family transposase IS1G | Transposase |
| PH219_RS23295 (20706) | 20706..21599 | - | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| PH219_RS23300 (21642) | 21642..22637 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| PH219_RS23305 (23102) | 23102..25240 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| PH219_RS23310 (25402) | 25402..25818 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PH219_RS23315 (25815) | 25815..26045 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PH219_RS23320 (26352) | 26352..29471 | + | 3120 | WP_023909028.1 | hypothetical protein | - |
| PH219_RS23325 (29734) | 29734..30867 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| PH219_RS23330 (30887) | 30887..31171 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| PH219_RS23335 (31168) | 31168..31365 | - | 198 | WP_000215657.1 | hypothetical protein | - |
| PH219_RS23340 (31999) | 31999..32217 | + | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PH219_RS23345 (32219) | 32219..32524 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PH219_RS23350 (32525) | 32525..33331 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| PH219_RS23355 (34105) | 34105..34860 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| PH219_RS23360 (35448) | 35448..36614 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| PH219_RS23365 (36614) | 36614..37585 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PH219_RS23370 (38452) | 38452..39354 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| PH219_RS23375 (39351) | 39351..39662 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| PH219_RS23380 (39739) | 39739..40422 | + | 684 | WP_000086185.1 | DNA methylase | - |
| PH219_RS23385 (40423) | 40423..40644 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| PH219_RS23390 (40574) | 40574..41092 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| PH219_RS23395 (41143) | 41143..41919 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| PH219_RS23400 (42336) | 42336..42761 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| PH219_RS23405 (42808) | 42808..43230 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| PH219_RS23410 (43227) | 43227..43418 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| PH219_RS23415 (44453) | 44453..44683 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| PH219_RS23420 (44735) | 44735..45793 | + | 1059 | Protein_51 | DUF3560 domain-containing protein | - |
| PH219_RS23425 (45787) | 45787..48180 | + | 2394 | Protein_52 | Multifunctional conjugation protein TraI | Relaxase |
| PH219_RS23430 (48200) | 48200..48946 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| PH219_RS23435 (49001) | 49001..49561 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| PH219_RS23440 (49692) | 49692..49904 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| PH219_RS23445 (50417) | 50417..50703 | + | 287 | Protein_56 | DUF2726 domain-containing protein | - |
| - (50670) | 50670..50730 | - | 61 | NuclAT_0 | - | - |
| - (50670) | 50670..50730 | - | 61 | NuclAT_0 | - | - |
| - (50670) | 50670..50730 | - | 61 | NuclAT_0 | - | - |
| - (50670) | 50670..50730 | - | 61 | NuclAT_0 | - | - |
| PH219_RS23450 (50775) | 50775..50909 | + | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| PH219_RS23455 (51206) | 51206..51460 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| PH219_RS23460 (51620) | 51620..52366 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| PH219_RS23465 (52381) | 52381..53922 | - | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| PH219_RS23470 (54284) | 54284..54358 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| PH219_RS23475 (54351) | 54351..55208 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| PH219_RS23480 (56148) | 56148..56801 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PH219_RS23485 (56894) | 56894..57151 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PH219_RS23490 (57084) | 57084..57485 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PH219_RS23495 (57622) | 57622..59958 | - | 2337 | Protein_66 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| PH219_RS23500 (60030) | 60030..60734 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23505 (60878) | 60878..61432 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| PH219_RS23510 (61563) | 61563..62393 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| PH219_RS23515 (62531) | 62531..62971 | + | 441 | Protein_70 | CatB-related O-acetyltransferase | - |
| PH219_RS23520 (63025) | 63025..63729 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PH219_RS23525 (63793) | 63793..64131 | + | 339 | Protein_72 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PH219_RS23530 (64314) | 64314..65174 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PH219_RS23535 (65321) | 65321..67792 | - | 2472 | Protein_74 | Tn3-like element TnAs3 family transposase | - |
| PH219_RS23540 (67795) | 67795..68355 | - | 561 | WP_000147567.1 | recombinase family protein | - |
| PH219_RS23545 (68368) | 68368..68688 | + | 321 | Protein_76 | IS1380 family transposase ISEcp1 | Transposase |
| PH219_RS23550 (68928) | 68928..69569 | + | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| PH219_RS23555 (69794) | 69794..70465 | - | 672 | Protein_78 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| PH219_RS23560 (70529) | 70529..71233 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| PH219_RS23565 (71283) | 71283..72002 | + | 720 | Protein_80 | helicase RepA family protein | - |
| PH219_RS23570 (71989) | 71989..72840 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| PH219_RS23575 (73148) | 73148..73963 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| PH219_RS23580 (74024) | 74024..74827 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PH219_RS23585 (74827) | 74827..75663 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| PH219_RS23590 (75724) | 75724..76428 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23595 (76593) | 76593..76886 | + | 294 | Protein_86 | IS30 family transposase ISAba125 | Transposase |
| PH219_RS23600 (76987) | 76987..77799 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| PH219_RS23605 (77803) | 77803..78168 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| PH219_RS23610 (78173) | 78173..78811 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| PH219_RS23615 (78822) | 78822..79379 | - | 558 | Protein_90 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| PH219_RS23620 (79479) | 79479..79853 | - | 375 | Protein_91 | protein-disulfide reductase DsbD family protein | - |
| PH219_RS23625 (80166) | 80166..81707 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| PH219_RS23630 (82112) | 82112..82951 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PH219_RS23635 (82945) | 82945..83292 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| PH219_RS23640 (83409) | 83409..84247 | - | 839 | Protein_95 | Streptomycin 3''-adenylyltransferase | ARG |
| PH219_RS23645 (84378) | 84378..84851 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| PH219_RS23650 (85009) | 85009..86022 | + | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| PH219_RS23655 (86225) | 86225..86533 | + | 309 | Protein_98 | EAL domain-containing protein | - |
| PH219_RS23660 (86424) | 86424..87128 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23665 (87287) | 87287..87568 | - | 282 | Protein_100 | transposase zinc-binding domain-containing protein | - |
| PH219_RS23670 (87715) | 87715..88575 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PH219_RS23675 (88758) | 88758..88949 | - | 192 | Protein_102 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PH219_RS23680 (89013) | 89013..89717 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PH219_RS23685 (89772) | 89772..90617 | - | 846 | Protein_104 | IS4 family transposase IS10R | Transposase |
| PH219_RS23690 (90727) | 90727..91689 | - | 963 | Protein_105 | IS4 family transposase IS10R | Transposase |
| PH219_RS23695 (91832) | 91832..92692 | + | 861 | WP_000557454.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| PH219_RS23700 (92705) | 92705..93247 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| PH219_RS23705 (93729) | 93729..93920 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| PH219_RS23710 (93944) | 93944..94171 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| PH219_RS23715 (94222) | 94222..95349 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| PH219_RS23720 (95386) | 95386..96090 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23725 (96212) | 96212..97118 | + | 907 | Protein_112 | hypothetical protein | ARG |
| PH219_RS23730 (97115) | 97115..98353 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PH219_RS23735 (98353) | 98353..98937 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PH219_RS23740 (99430) | 99430..100194 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| PH219_RS23745 (100334) | 100334..101038 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| PH219_RS23750 (101093) | 101093..101959 | - | 867 | Protein_117 | class 1 integron integrase IntI1 | - |
| PH219_RS23755 (102104) | 102104..102601 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| PH219_RS23760 (102713) | 102713..103003 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|