MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 129047 bp
Accession: NZ_CP113192 Location: 670186..799232 Organism: Klebsiella pneumoniae strain SXC4-2 Replicon: chromosome
Accession: NZ_CP113192 Location: 670186..799232 Organism: Klebsiella pneumoniae strain SXC4-2 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OT483_RS03275 (665736) | 665736..667481 | - | 1746 | WP_002917631.1 | DNA primase | - |
| OT483_RS03280 (667593) | 667593..667808 | - | 216 | WP_001144069.1 | 30S ribosomal protein S21 | - |
| OT483_RS03285 (668046) | 668046..669059 | + | 1014 | WP_002916879.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| OT483_RS03290 (669104) | 669104..670711 | - | 1608 | WP_002916878.1 | cytosine permease | - |
| OT483_RS03295 (670865) | 670865..671482 | - | 618 | WP_002916877.1 | urease accessory protein UreG | - |
| OT483_RS03300 (671491) | 671491..672165 | - | 675 | WP_004150924.1 | urease accessory protein UreF | - |
| OT483_RS03305 (672167) | 672167..672643 | - | 477 | WP_002916875.1 | urease accessory protein UreE | - |
| OT483_RS03310 (672653) | 672653..674356 | - | 1704 | WP_002916874.1 | urease subunit alpha | - |
| OT483_RS03315 (674349) | 674349..674669 | - | 321 | WP_002916872.1 | urease subunit beta | - |
| OT483_RS03320 (674679) | 674679..674981 | - | 303 | WP_002916871.1 | urease subunit gamma | - |
| OT483_RS03325 (674991) | 674991..675815 | - | 825 | WP_002916869.1 | urease accessory protein UreD | - |
| OT483_RS03330 (675805) | 675805..675951 | + | 147 | WP_004144529.1 | short-chain dehydrogenase | - |
| OT483_RS03335 (675962) | 675962..676081 | - | 120 | WP_004217172.1 | hypothetical protein | - |
| OT483_RS03340 (676213) | 676213..676830 | - | 618 | WP_002916866.1 | glycerol-3-phosphate 1-O-acyltransferase PlsY | - |
| OT483_RS03345 (676938) | 676938..677321 | + | 384 | WP_004150923.1 | bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase | - |
| OT483_RS03350 (677520) | 677520..678341 | + | 822 | WP_004144532.1 | undecaprenyl-diphosphate phosphatase | - |
| OT483_RS03355 (678353) | 678353..679594 | - | 1242 | WP_002916864.1 | multifunctional CCA addition/repair protein | - |
| OT483_RS03360 (679656) | 679656..680276 | - | 621 | WP_002916862.1 | TIGR04211 family SH3 domain-containing protein | - |
| OT483_RS03365 (680491) | 680491..681789 | + | 1299 | WP_004150922.1 | inorganic triphosphatase | - |
| OT483_RS03370 (681810) | 681810..684647 | + | 2838 | WP_002916860.1 | bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase | - |
| OT483_RS03375 (684706) | 684706..686139 | + | 1434 | WP_002916858.1 | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | - |
| OT483_RS03380 (686217) | 686217..686366 | - | 150 | WP_004144536.1 | hypothetical protein | - |
| OT483_RS03385 (686358) | 686358..686555 | + | 198 | WP_002916857.1 | cell surface composition regulator GlgS | - |
| OT483_RS03390 (686591) | 686591..686863 | - | 273 | WP_002916856.1 | accessory factor UbiK family protein | - |
| OT483_RS03395 (687241) | 687241..687894 | + | 654 | WP_002916855.1 | 3,4-dihydroxy-2-butanone-4-phosphate synthase | - |
| OT483_RS03400 (687956) | 687956..688726 | - | 771 | WP_002916852.1 | zinc transporter ZupT | - |
| OT483_RS03405 (688913) | 688913..689704 | + | 792 | WP_002916851.1 | 4,5-DOPA dioxygenase extradiol | - |
| OT483_RS03410 (689749) | 689749..690909 | - | 1161 | WP_002916850.1 | glutathionylspermidine synthase family protein | - |
| OT483_RS03415 (690915) | 690915..691586 | - | 672 | WP_002916849.1 | DUF1190 family protein | - |
| OT483_RS03420 (691754) | 691754..693223 | - | 1470 | WP_004150921.1 | outer membrane channel protein TolC | - |
| OT483_RS03425 (693420) | 693420..694052 | + | 633 | WP_002916848.1 | ADP-ribose diphosphatase | - |
| OT483_RS03430 (694049) | 694049..694471 | + | 423 | WP_002916847.1 | DUF1249 family protein | - |
| OT483_RS03435 (694496) | 694496..695323 | + | 828 | WP_002916846.1 | 3',5'-cyclic-AMP phosphodiesterase | - |
| OT483_RS03440 (695323) | 695323..695898 | + | 576 | WP_002916845.1 | esterase YqiA | - |
| OT483_RS03445 (695929) | 695929..697824 | + | 1896 | WP_002916844.1 | DNA topoisomerase IV subunit B | - |
| OT483_RS03450 (697897) | 697897..698211 | - | 315 | WP_002916842.1 | putative quinol monooxygenase | - |
| OT483_RS03455 (698292) | 698292..698873 | - | 582 | WP_002916840.1 | NAD(P)H-dependent oxidoreductase | - |
| OT483_RS03460 (698980) | 698980..700329 | - | 1350 | WP_002916838.1 | quorum sensing histidine kinase QseC | - |
| OT483_RS03465 (700326) | 700326..700985 | - | 660 | WP_002916836.1 | quorum sensing response regulator transcription factor QseB | - |
| OT483_RS03470 (701136) | 701136..701531 | + | 396 | WP_002916833.1 | YgiW/YdeI family stress tolerance OB fold protein | - |
| OT483_RS03475 (701609) | 701609..702478 | + | 870 | WP_002916831.1 | AraC family transcriptional regulator | - |
| OT483_RS03480 (702600) | 702600..704858 | + | 2259 | WP_002916828.1 | DNA topoisomerase IV subunit A | - |
| OT483_RS03485 (705050) | 705050..705787 | + | 738 | WP_002916826.1 | 1-acylglycerol-3-phosphate O-acyltransferase | - |
| OT483_RS03490 (705871) | 705871..707283 | + | 1413 | WP_004144547.1 | cell division protein FtsP | - |
| OT483_RS03495 (707317) | 707317..709648 | + | 2332 | Protein_685 | YgiQ family radical SAM protein | - |
| OT483_RS03500 (709648) | 709648..710175 | + | 528 | WP_004150920.1 | GNAT family N-acetyltransferase | - |
| OT483_RS03505 (710211) | 710211..711038 | - | 828 | WP_002916796.1 | 2,5-didehydrogluconate reductase DkgA | - |
| OT483_RS03510 (711184) | 711184..712347 | - | 1164 | WP_002916794.1 | alcohol dehydrogenase | - |
| OT483_RS03515 (712544) | 712544..713443 | + | 900 | WP_004144552.1 | AraC family transcriptional regulator | - |
| OT483_RS03520 (713494) | 713494..714153 | - | 660 | WP_002916791.1 | DedA family general envelope maintenance protein YghB | - |
| OT483_RS03525 (714285) | 714285..715472 | - | 1188 | WP_004149836.1 | cystathionine beta-lyase | - |
| OT483_RS03530 (715723) | 715723..716454 | + | 732 | WP_002916787.1 | tol-pal system-associated acyl-CoA thioesterase | - |
| OT483_RS03535 (716461) | 716461..716886 | + | 426 | WP_002916785.1 | TonB system transport protein ExbD | - |
| OT483_RS03540 (717091) | 717091..718509 | + | 1419 | WP_002916782.1 | MFS transporter | - |
| OT483_RS03545 (718523) | 718523..720046 | + | 1524 | WP_002916780.1 | glycoside hydrolase 43 family protein | - |
| OT483_RS03550 (720153) | 720153..720647 | + | 495 | WP_004105804.1 | TIGR00645 family protein | - |
| OT483_RS03555 (720769) | 720769..721656 | + | 888 | WP_004144560.1 | YghX family hydrolase | - |
| OT483_RS03560 (721735) | 721735..722022 | + | 288 | WP_002916743.1 | DUF2623 domain-containing protein | - |
| OT483_RS03565 (722095) | 722095..722961 | - | 867 | WP_002916742.1 | glutathione-dependent disulfide-bond oxidoreductase | - |
| OT483_RS03570 (723009) | 723009..723569 | - | 561 | WP_004150918.1 | thioredoxin domain-containing protein | - |
| OT483_RS03575 (723590) | 723590..723712 | + | 123 | WP_004217169.1 | hypothetical protein | - |
| OT483_RS03580 (723789) | 723789..725654 | + | 1866 | WP_002916740.1 | bifunctional glutathionylspermidine amidase/synthase | - |
| OT483_RS03585 (725800) | 725800..726981 | + | 1182 | WP_002916739.1 | PLP-dependent aminotransferase family protein | - |
| OT483_RS03590 (727158) | 727158..727346 | - | 189 | WP_002916738.1 | hypothetical protein | - |
| OT483_RS03595 (727546) | 727546..727890 | - | 345 | WP_004174409.1 | hypothetical protein | - |
| OT483_RS03600 (727977) | 727977..728579 | - | 603 | WP_002916735.1 | short chain dehydrogenase | - |
| OT483_RS03605 (728677) | 728677..729588 | + | 912 | WP_004188550.1 | LysR family transcriptional regulator | - |
| OT483_RS03610 (729589) | 729589..730737 | - | 1149 | WP_004150915.1 | PLP-dependent aspartate aminotransferase family protein | - |
| OT483_RS03615 (730748) | 730748..732118 | - | 1371 | WP_219716907.1 | cystathionine beta-synthase | - |
| OT483_RS03620 (732763) | 732763..733056 | + | 294 | WP_004150912.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| OT483_RS03625 (733053) | 733053..733538 | + | 486 | WP_004150910.1 | GNAT family N-acetyltransferase | Toxin Detail |
| OT483_RS03630 (734242) | 734242..734835 | + | 594 | WP_004188553.1 | hypothetical protein | - |
| OT483_RS03635 (734932) | 734932..735148 | + | 217 | Protein_713 | IS3 family transposase ISYpe1 | Transposase |
| OT483_RS03640 (735754) | 735754..736626 | + | 873 | WP_004188557.1 | ParA family protein | - |
| OT483_RS03645 (736626) | 736626..737009 | + | 384 | WP_004150906.1 | hypothetical protein | - |
| OT483_RS03650 (737002) | 737002..738369 | + | 1368 | WP_004150905.1 | SPI-7-type island replicative DNA helicase | - |
| OT483_RS03655 (738366) | 738366..739988 | + | 1623 | WP_004150904.1 | transcriptional regulator | - |
| OT483_RS03660 (739988) | 739988..740572 | + | 585 | WP_004150903.1 | DUF2857 domain-containing protein | - |
| OT483_RS03665 (740572) | 740572..741789 | + | 1218 | WP_004150902.1 | STY4528 family pathogenicity island replication protein | - |
| OT483_RS03670 (741874) | 741874..742749 | - | 876 | WP_004150901.1 | hypothetical protein | - |
| OT483_RS03675 (742931) | 742931..744259 | + | 1329 | WP_004150900.1 | WG repeat-containing protein | - |
| OT483_RS03680 (744650) | 744650..744841 | + | 192 | Protein_722 | DUF2321 domain-containing protein | - |
| OT483_RS03685 (744920) | 744920..745405 | + | 486 | WP_004150899.1 | hypothetical protein | - |
| OT483_RS03690 (745481) | 745481..746182 | - | 702 | WP_004227625.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| OT483_RS03695 (746347) | 746347..747432 | - | 1086 | WP_004150897.1 | type IV toxin-antitoxin system AbiEi family antitoxin | - |
| OT483_RS03700 (747826) | 747826..748548 | + | 723 | WP_004150896.1 | TIGR03761 family integrating conjugative element protein | - |
| OT483_RS03705 (748541) | 748541..748678 | + | 138 | WP_014343427.1 | hypothetical protein | - |
| OT483_RS03710 (749265) | 749265..749717 | + | 453 | WP_004150895.1 | STY4534 family ICE replication protein | - |
| OT483_RS03715 (749841) | 749841..750410 | + | 570 | WP_004150894.1 | PilL N-terminal domain-containing protein | - |
| OT483_RS03720 (750410) | 750410..751150 | + | 741 | WP_004150893.1 | hypothetical protein | - |
| OT483_RS03725 (751264) | 751264..751881 | + | 618 | WP_004153005.1 | TIGR03759 family integrating conjugative element protein | - |
| OT483_RS03730 (751860) | 751860..752429 | + | 570 | WP_004150891.1 | transglycosylase SLT domain-containing protein | - |
| OT483_RS03735 (752426) | 752426..752938 | + | 513 | WP_004153655.1 | integrating conjugative element protein | - |
| OT483_RS03740 (752976) | 752976..755075 | + | 2100 | WP_004150889.1 | type IV conjugative transfer system coupling protein TraD | - |
| OT483_RS03745 (755072) | 755072..755335 | + | 264 | WP_004150888.1 | hypothetical protein | - |
| OT483_RS03750 (755335) | 755335..756093 | + | 759 | WP_004150887.1 | TIGR03747 family integrating conjugative element membrane protein | - |
| OT483_RS03755 (756195) | 756195..756671 | + | 477 | WP_004150886.1 | hypothetical protein | - |
| OT483_RS03760 (756931) | 756931..757605 | - | 675 | WP_004217767.1 | hypothetical protein | - |
| OT483_RS03765 (758054) | 758054..758371 | + | 318 | WP_004150884.1 | RAQPRD family integrative conjugative element protein | - |
| OT483_RS03770 (758368) | 758368..758604 | + | 237 | WP_004150883.1 | TIGR03758 family integrating conjugative element protein | - |
| OT483_RS03775 (758619) | 758619..758972 | + | 354 | WP_004150882.1 | TIGR03745 family integrating conjugative element membrane protein | - |
| OT483_RS03780 (758982) | 758982..759353 | + | 372 | WP_004150881.1 | TIGR03750 family conjugal transfer protein | - |
| OT483_RS03785 (759350) | 759350..760003 | + | 654 | WP_004150880.1 | TIGR03746 family integrating conjugative element protein | - |
| OT483_RS03790 (760003) | 760003..760848 | + | 846 | WP_004150879.1 | TIGR03749 family integrating conjugative element protein | - |
| OT483_RS03795 (760845) | 760845..762329 | + | 1485 | WP_004217763.1 | TIGR03752 family integrating conjugative element protein | - |
| OT483_RS03800 (762343) | 762343..762741 | + | 399 | WP_004150877.1 | TIGR03751 family conjugal transfer lipoprotein | - |
| OT483_RS03805 (762738) | 762738..765515 | + | 2778 | WP_004188577.1 | conjugative transfer ATPase | - |
| OT483_RS03810 (766017) | 766017..766508 | - | 492 | WP_251919674.1 | hypothetical protein | - |
| OT483_RS03815 (767017) | 767017..767018 | - | 2 | WP_244428432.1 | IS1-like element IS1B family transposase | - |
| OT483_RS03820 (767345) | 767345..768711 | - | 1367 | Protein_750 | glycosaminoglycan attachment protein | - |
| OT483_RS03825 (768921) | 768921..769934 | - | 1014 | WP_267717517.1 | hypothetical protein | - |
| OT483_RS03830 (770149) | 770149..770760 | + | 612 | WP_171487584.1 | SymE family type I addiction module toxin | - |
| OT483_RS03835 (770966) | 770966..771975 | + | 1010 | Protein_753 | hypothetical protein | - |
| OT483_RS03840 (772179) | 772179..773774 | + | 1596 | WP_267717519.1 | hypothetical protein | - |
| OT483_RS03845 (773892) | 773892..774287 | + | 396 | WP_004152606.1 | TIGR03757 family integrating conjugative element protein | - |
| OT483_RS03850 (774284) | 774284..775225 | + | 942 | WP_004152607.1 | TIGR03756 family integrating conjugative element protein | - |
| OT483_RS03855 (775241) | 775241..776662 | + | 1422 | WP_004153700.1 | integrating conjugative element protein | - |
| OT483_RS03860 (776659) | 776659..777000 | + | 342 | WP_004152609.1 | hypothetical protein | - |
| OT483_RS03865 (777003) | 777003..778532 | + | 1530 | WP_004152610.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| OT483_RS03870 (778576) | 778576..778875 | - | 300 | WP_004152611.1 | hypothetical protein | - |
| OT483_RS03875 (779100) | 779100..779351 | - | 252 | WP_004152612.1 | helix-turn-helix transcriptional regulator | - |
| OT483_RS03880 (779455) | 779455..779700 | + | 246 | WP_004155677.1 | helix-turn-helix transcriptional regulator | - |
| OT483_RS03885 (779779) | 779779..780234 | - | 456 | WP_004152613.1 | cold shock domain-containing protein | - |
| OT483_RS03890 (780375) | 780375..780635 | - | 261 | WP_004152614.1 | helix-turn-helix transcriptional regulator | - |
| OT483_RS03895 (780738) | 780738..780998 | + | 261 | WP_004152615.1 | helix-turn-helix transcriptional regulator | - |
| OT483_RS03900 (781049) | 781049..781426 | - | 378 | WP_004154982.1 | hypothetical protein | - |
| OT483_RS03905 (781678) | 781678..781986 | + | 309 | WP_202174770.1 | hypothetical protein | - |
| OT483_RS03910 (781990) | 781990..782130 | + | 141 | WP_004151757.1 | hypothetical protein | - |
| OT483_RS03915 (783144) | 783144..784037 | + | 894 | WP_004151758.1 | Holliday junction ATP-dependent DNA helicase RuvA ; Integrase | Integrase |
| OT483_RS03920 (784042) | 784042..784995 | - | 954 | WP_004151759.1 | hypothetical protein | - |
| OT483_RS03925 (785340) | 785340..785618 | + | 279 | WP_004151760.1 | hypothetical protein | - |
| OT483_RS03930 (785701) | 785701..786099 | + | 399 | WP_004151761.1 | antirestriction protein | - |
| OT483_RS03935 (786197) | 786197..786544 | + | 348 | WP_004151762.1 | hypothetical protein | - |
| OT483_RS03940 (786647) | 786647..787252 | + | 606 | WP_004151763.1 | DUF3085 domain-containing protein | - |
| OT483_RS03945 (787336) | 787336..788316 | + | 981 | WP_004151764.1 | zincin-like metallopeptidase domain-containing protein | - |
| OT483_RS03950 (788451) | 788451..789740 | + | 1290 | WP_004188585.1 | TraI domain-containing protein | - |
| OT483_RS03955 (789904) | 789904..790704 | + | 801 | WP_004217751.1 | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabL ; Integrase | Integrase |
| OT483_RS03960 (791055) | 791055..791897 | - | 843 | WP_064143480.1 | DUF4942 domain-containing protein | - |
| OT483_RS03965 (791982) | 791982..792179 | - | 198 | WP_023563519.1 | DUF957 domain-containing protein | - |
| OT483_RS03970 (792207) | 792207..792404 | - | 198 | Protein_780 | DUF5983 family protein | - |
| OT483_RS03975 (792401) | 792401..792778 | - | 378 | WP_064143481.1 | TA system toxin CbtA family protein | Toxin Detail |
| OT483_RS03980 (792825) | 792825..793202 | - | 378 | WP_064143482.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin Detail |
| OT483_RS03985 (793282) | 793282..793503 | - | 222 | WP_000692312.1 | DUF987 domain-containing protein | - |
| OT483_RS03990 (793566) | 793566..794042 | - | 477 | WP_064143483.1 | RadC family protein | - |
| OT483_RS03995 (794058) | 794058..794543 | - | 486 | WP_000214414.1 | antirestriction protein | - |
| OT483_RS04000 (794635) | 794635..795423 | - | 789 | WP_064143484.1 | DUF932 domain-containing protein | - |
| OT483_RS04005 (795514) | 795514..795747 | - | 234 | WP_001117568.1 | DUF905 family protein | - |
| OT483_RS04010 (795818) | 795818..798664 | - | 2847 | WP_064143485.1 | Ag43/Cah family autotransporter adhesin | - |
| OT483_RS04015 (799036) | 799036..799908 | - | 873 | WP_023145612.1 | GTPase family protein | - |
| OT483_RS04020 (800018) | 800018..801037 | - | 1020 | WP_023145611.1 | hypothetical protein | - |
| OT483_RS04025 (802226) | 802226..802372 | - | 147 | Protein_791 | IS1 family transposase | - |
| OT483_RS04030 (802343) | 802343..802627 | + | 285 | WP_000453440.1 | hypothetical protein | - |
| OT483_RS04035 (802629) | 802629..803201 | - | 573 | WP_001170555.1 | hypothetical protein | - |
| OT483_RS04040 (803287) | 803287..803493 | - | 207 | WP_000856891.1 | AlpA family transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|