MGE detailed information
MGE type: Conjugative plasmid MGE length: 111292 bp
Accession: NZ_CP103509 Location: 1..111292 Organism: Escherichia coli O25b:H4-ST131 strain 5506 Replicon: plasmid pMB9366_1
Accession: NZ_CP103509 Location: 1..111292 Organism: Escherichia coli O25b:H4-ST131 strain 5506 Replicon: plasmid pMB9366_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T03_RS24510 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| M5T03_RS24515 (1263) | 1263..2003 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| M5T03_RS24520 (2124) | 2124..2312 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| M5T03_RS24525 (2679) | 2679..3848 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| M5T03_RS24530 (4074) | 4074..4249 | - | 176 | Protein_4 | IS3 family transposase | - |
| M5T03_RS24535 (4695) | 4695..4967 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| M5T03_RS24540 (5504) | 5504..5928 | - | 425 | Protein_6 | IS3 family transposase IS2 | Transposase |
| M5T03_RS24545 (6210) | 6210..8180 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| M5T03_RS24550 (8187) | 8187..8978 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| M5T03_RS24555 (9041) | 9041..9649 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| M5T03_RS24560 (9717) | 9717..10499 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| M5T03_RS24565 (10496) | 10496..11518 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| M5T03_RS24570 (11604) | 11604..12549 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| M5T03_RS24575 (12598) | 12598..12945 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| M5T03_RS24580 (12942) | 12942..13346 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| M5T03_RS24585 (13426) | 13426..13764 | - | 339 | Protein_15 | IS3 family transposase IS629 | Transposase |
| M5T03_RS24590 (13848) | 13848..15356 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| M5T03_RS24595 (16029) | 16029..16768 | - | 740 | Protein_17 | IS3 family transposase IS629 | Transposase |
| M5T03_RS24600 (16794) | 16794..17099 | + | 306 | Protein_18 | IS91 family transposase ISSbo1 | Transposase |
| M5T03_RS24605 (17622) | 17622..18797 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| M5T03_RS24610 (18866) | 18866..21127 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| M5T03_RS24615 (21296) | 21296..22072 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| M5T03_RS24620 (22080) | 22080..22955 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| M5T03_RS24625 (23329) | 23329..23954 | - | 626 | Protein_23 | replication initiation protein | - |
| M5T03_RS24630 (25406) | 25406..25741 | - | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| M5T03_RS24635 (25870) | 25870..26217 | + | 348 | WP_000142452.1 | DUF6404 family protein | - |
| M5T03_RS24640 (26237) | 26237..26746 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| M5T03_RS24645 (26743) | 26743..27003 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| M5T03_RS24650 (27105) | 27105..27844 | + | 740 | Protein_28 | IS3 family transposase IS629 | Transposase |
| M5T03_RS24655 (28517) | 28517..28831 | + | 315 | Protein_29 | IS5 family transposase ISKpn26 | Transposase |
| M5T03_RS24660 (28832) | 28832..29005 | + | 174 | Protein_30 | IS5 family transposase ISKpn26 | Transposase |
| M5T03_RS24665 (29155) | 29155..29788 | - | 634 | Protein_31 | histidine-type phosphatase | - |
| M5T03_RS24670 (29910) | 29910..30395 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| M5T03_RS24675 (30420) | 30420..30905 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| M5T03_RS24680 (30892) | 30892..31587 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| M5T03_RS24685 (31592) | 31592..32722 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| M5T03_RS24690 (32712) | 32712..33995 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| M5T03_RS24695 (33998) | 33998..35377 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| M5T03_RS24700 (35481) | 35481..36008 | - | 528 | WP_000178050.1 | iron transporter | - |
| M5T03_RS24705 (36049) | 36049..37935 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| M5T03_RS24710 (38282) | 38282..39043 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| M5T03_RS24715 (39280) | 39280..39786 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| M5T03_RS24720 (39776) | 39776..39946 | - | 171 | Protein_42 | DsbA family protein | - |
| M5T03_RS24725 (40084) | 40084..40197 | - | 114 | Protein_43 | IS6 family transposase | - |
| M5T03_RS24730 (40397) | 40397..41082 | + | 686 | Protein_44 | IS1 family transposase IS1R | Transposase |
| M5T03_RS24735 (41136) | 41136..41840 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T03_RS24740 (41961) | 41961..42821 | + | 861 | WP_259425961.1 | Beta-lactamase TEM | ARG |
| M5T03_RS24745 (42971) | 42971..43069 | - | 99 | Protein_47 | IS1 family transposase | - |
| M5T03_RS24750 (43098) | 43098..44408 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| M5T03_RS24755 (44693) | 44693..45094 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5T03_RS24760 (45027) | 45027..45284 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5T03_RS24765 (45377) | 45377..46030 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5T03_RS24770 (46970) | 46970..47827 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| M5T03_RS24775 (47820) | 47820..47894 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| M5T03_RS24780 (47894) | 47894..48025 | - | 132 | Protein_54 | protein CopA/IncA | - |
| M5T03_RS24785 (48131) | 48131..48385 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| M5T03_RS24790 (48682) | 48682..48816 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (48861) | 48861..48921 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (48861) | 48861..48921 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (48861) | 48861..48921 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (48861) | 48861..48921 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| M5T03_RS24795 (48888) | 48888..49174 | - | 287 | Protein_57 | DUF2726 domain-containing protein | - |
| M5T03_RS24800 (49252) | 49252..50865 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| M5T03_RS24805 (50896) | 50896..51246 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| M5T03_RS24810 (51243) | 51243..51668 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| M5T03_RS24815 (52227) | 52227..52439 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| M5T03_RS24820 (52570) | 52570..53130 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| M5T03_RS24825 (53185) | 53185..53931 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| M5T03_RS24830 (53951) | 53951..59221 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5T03_RS24835 (59221) | 59221..61437 | - | 2217 | WP_023356304.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5T03_RS24840 (61434) | 61434..62213 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| M5T03_RS24845 (62416) | 62416..63147 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| M5T03_RS24850 (63179) | 63179..63646 | - | 468 | WP_259425962.1 | entry exclusion protein | - |
| M5T03_RS24855 (63696) | 63696..64393 | + | 698 | WP_223216367.1 | IS1 family transposase IS1G | Transposase |
| M5T03_RS24860 (64387) | 64387..64731 | - | 345 | WP_259425959.1 | P-type conjugative transfer protein TrbJ | - |
| M5T03_RS24865 (64661) | 64661..65206 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5T03_RS24870 (65193) | 65193..65477 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5T03_RS24875 (65604) | 65604..65924 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| M5T03_RS24885 (66703) | 66703..66954 | - | 252 | WP_123058820.1 | hypothetical protein | - |
| M5T03_RS24890 (66984) | 66984..67976 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| M5T03_RS24895 (67973) | 67973..68605 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| M5T03_RS24900 (68602) | 68602..68988 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| M5T03_RS24905 (68985) | 68985..71612 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| M5T03_RS24910 (71772) | 71772..71993 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| M5T03_RS24915 (72128) | 72128..72643 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5T03_RS24920 (72643) | 72643..72954 | - | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| M5T03_RS24925 (72941) | 72941..73507 | - | 567 | WP_001617877.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M5T03_RS24930 (73497) | 73497..74948 | - | 1452 | WP_000146687.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5T03_RS24935 (74948) | 74948..75676 | - | 729 | WP_001230808.1 | type-F conjugative transfer system secretin TraK | - |
| M5T03_RS24940 (75663) | 75663..76229 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| M5T03_RS24945 (76251) | 76251..76562 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| M5T03_RS24950 (76567) | 76567..76929 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| M5T03_RS24955 (76963) | 76963..77190 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| M5T03_RS24960 (77278) | 77278..77955 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| M5T03_RS24965 (78089) | 78089..78472 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5T03_RS24970 (78803) | 78803..79405 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| M5T03_RS24975 (79702) | 79702..80523 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| M5T03_RS24980 (80642) | 80642..80930 | - | 289 | Protein_94 | hypothetical protein | - |
| M5T03_RS24985 (80955) | 80955..81161 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| M5T03_RS24990 (81231) | 81231..81404 | + | 174 | Protein_96 | hypothetical protein | - |
| M5T03_RS24995 (81402) | 81402..81632 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| M5T03_RS25000 (81852) | 81852..81977 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M5T03_RS25005 (81919) | 81919..82068 | - | 150 | Protein_99 | plasmid maintenance protein Mok | - |
| - (82054) | 82054..82094 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (82054) | 82054..82094 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (82054) | 82054..82094 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (82054) | 82054..82094 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - (83538) | 83538..83724 | - | 187 | NuclAT_0 | - | - |
| - (83538) | 83538..83724 | - | 187 | NuclAT_0 | - | - |
| - (83538) | 83538..83724 | - | 187 | NuclAT_0 | - | - |
| - (83538) | 83538..83724 | - | 187 | NuclAT_0 | - | - |
| M5T03_RS25015 (83693) | 83693..84455 | - | 763 | Protein_101 | plasmid SOS inhibition protein A | - |
| M5T03_RS25020 (84452) | 84452..84886 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| M5T03_RS25025 (84941) | 84941..86899 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| M5T03_RS25030 (86965) | 86965..87198 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| M5T03_RS25035 (87261) | 87261..87758 | - | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| M5T03_RS25040 (87908) | 87908..89809 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| M5T03_RS25045 (90487) | 90487..90693 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| M5T03_RS25050 (90606) | 90606..90941 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| M5T03_RS25055 (90934) | 90934..91191 | - | 258 | WP_023147917.1 | hypothetical protein | - |
| M5T03_RS25060 (91104) | 91104..91316 | - | 213 | WP_001348622.1 | hypothetical protein | - |
| M5T03_RS25065 (91342) | 91342..91905 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| M5T03_RS25070 (91953) | 91953..93314 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| M5T03_RS25075 (93366) | 93366..93596 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T03_RS25080 (94631) | 94631..94822 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| M5T03_RS25085 (94819) | 94819..95241 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| M5T03_RS25090 (95288) | 95288..95713 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| M5T03_RS25095 (96130) | 96130..96906 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| M5T03_RS25100 (96957) | 96957..97475 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| M5T03_RS25105 (97405) | 97405..97626 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| M5T03_RS25110 (97627) | 97627..98310 | - | 684 | WP_000086185.1 | DNA methylase | - |
| M5T03_RS25115 (98387) | 98387..98698 | - | 312 | WP_032143366.1 | hypothetical protein | - |
| M5T03_RS25120 (98695) | 98695..99597 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| M5T03_RS25125 (100464) | 100464..101435 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5T03_RS25130 (101435) | 101435..102601 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| M5T03_RS25135 (103189) | 103189..103944 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| M5T03_RS25140 (104718) | 104718..105524 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| M5T03_RS25145 (105525) | 105525..105830 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| M5T03_RS25150 (105832) | 105832..106050 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| M5T03_RS25155 (106758) | 106758..107753 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| M5T03_RS25160 (107796) | 107796..108410 | + | 615 | WP_259425960.1 | S-4TM family putative pore-forming effector | - |
| M5T03_RS25170 (109249) | 109249..109407 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| M5T03_RS25175 (109566) | 109566..110537 | - | 972 | Protein_133 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|