NZ_CP0950841..144934

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 144934 bp
Accession: NZ_CP095084        Location: 1..144934         Organism: Escherichia coli strain EC6868       Replicon: plasmid pEC6868-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUK76_RS25600 (2170) 2170..2388 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA -
MUK76_RS25605 (2390) 2390..2693 + 304 Protein_1 type II toxin-antitoxin system toxin CcdB -
MUK76_RS25610 (2694) 2694..3503 + 810 WP_000016979.1 site-specific integrase -
MUK76_RS25615 (3641) 3641..3916 - 276 WP_000239529.1 hypothetical protein -
MUK76_RS25620 (3910) 3910..4576 - 667 Protein_4 division plane positioning ATPase MipZ -
MUK76_RS25625 (4808) 4808..5777 + 970 Protein_5 plasmid segregation protein ParM -
MUK76_RS25630 (5782) 5782..6174 + 393 WP_000340835.1 plasmid partitioning/stability family protein -
MUK76_RS25635 (6179) 6179..6430 - 252 Protein_7 DUF4113 domain-containing protein -
MUK76_RS25640 (6492) 6492..7288 - 797 Protein_8 IS21 family transposase IS21 Transposase
MUK76_RS25645 (7288) 7288..8460 - 1173 WP_000952372.1 IS21 family transposase IS21 Transposase
MUK76_RS25650 (8562) 8562..9583 - 1022 Protein_10 translesion error-prone DNA polymerase V subunit UmuC -
MUK76_RS25655 (9583) 9583..10021 - 439 Protein_11 translesion error-prone DNA polymerase V autoproteolytic subunit -
MUK76_RS25660 (10018) 10018..10266 - 249 WP_000619112.1 DinI-like family protein -
MUK76_RS25665 (10401) 10401..10919 + 519 WP_000115885.1 hypothetical protein VF
MUK76_RS25670 (10938) 10938..12155 + 1218 Protein_14 ISL3-like element ISEc53 family transposase -
MUK76_RS25675 (12551) 12551..13477 + 927 Protein_15 DUF1281 domain-containing protein -
MUK76_RS25680 (13474) 13474..13785 + 312 WP_001310011.1 hypothetical protein -
MUK76_RS25685 (13861) 13861..14544 + 684 WP_000086169.1 DNA methylase -
MUK76_RS25690 (14545) 14545..14766 + 222 WP_001104873.1 hypothetical protein -
MUK76_RS25695 (14696) 14696..15214 + 519 WP_223364201.1 DUF1380 family protein -
MUK76_RS25700 (15259) 15259..16005 + 747 Protein_20 hypothetical protein -
MUK76_RS25705 (16441) 16441..16865 + 425 Protein_21 antirestriction protein -
MUK76_RS25710 (16912) 16912..17334 + 423 Protein_22 hypothetical protein -
MUK76_RS25715 (17331) 17331..17522 + 192 WP_001027516.1 hypothetical protein -
MUK76_RS25720 (17499) 17499..17971 - 473 Protein_24 hypothetical protein -
MUK76_RS25725 (18483) 18483..18713 + 231 WP_000155844.1 hypothetical protein -
MUK76_RS25730 (18765) 18765..20133 + 1369 Protein_26 DUF3560 domain-containing protein -
MUK76_RS25735 (20180) 20180..20744 + 565 Protein_27 class I SAM-dependent methyltransferase -
MUK76_RS25740 (20829) 20829..21281 - 453 WP_024185774.1 hypothetical protein -
MUK76_RS25745 (21583) 21583..22110 + 528 WP_000290833.1 single-stranded DNA-binding protein -
MUK76_RS25750 (22167) 22167..22400 + 234 WP_000006018.1 DUF905 domain-containing protein -
MUK76_RS25755 (22459) 22459..24420 + 1962 WP_244750114.1 ParB/RepB/Spo0J family partition protein -
MUK76_RS25760 (24475) 24475..24909 + 435 WP_000845910.1 conjugation system SOS inhibitor PsiB -
MUK76_RS25765 (24906) 24906..25666 + 761 Protein_33 plasmid SOS inhibition protein A -
- (25634) 25634..25833 + 200 NuclAT_0 - Antitoxin Detail
- (25634) 25634..25833 + 200 NuclAT_0 - Antitoxin Detail
- (25634) 25634..25833 + 200 NuclAT_0 - Antitoxin Detail
- (25634) 25634..25833 + 200 NuclAT_0 - Antitoxin Detail
MUK76_RS25770 (25840) 25840..25989 + 150 Protein_34 DUF5431 family protein -
MUK76_RS25775 (25931) 25931..26056 + 126 WP_096937776.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
MUK76_RS25780 (26373) 26373..26670 - 298 Protein_36 hypothetical protein -
MUK76_RS25785 (26971) 26971..27258 + 288 WP_000107526.1 hypothetical protein -
MUK76_RS25790 (27377) 27377..28199 + 823 Protein_38 DUF932 domain-containing protein -
MUK76_RS25795 (28493) 28493..29001 - 509 Protein_39 hypothetical protein VF
MUK76_RS25800 (29423) 29423..29806 + 384 WP_001151562.1 conjugal transfer relaxosome DNA-binding protein TraM -
MUK76_RS25805 (29999) 29999..30683 + 685 Protein_41 PAS domain-containing protein -
MUK76_RS25810 (30777) 30777..31004 + 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
MUK76_RS25815 (31038) 31038..31397 + 360 WP_001098988.1 type IV conjugative transfer system pilin TraA -
MUK76_RS25820 (31412) 31412..31723 + 312 WP_000012100.1 type IV conjugative transfer system protein TraL -
MUK76_RS25825 (31745) 31745..32311 + 567 WP_000399776.1 type IV conjugative transfer system protein TraE -
MUK76_RS25830 (32298) 32298..33024 + 727 Protein_46 type-F conjugative transfer system secretin TraK -
MUK76_RS25835 (33024) 33024..34451 + 1428 Protein_47 F-type conjugal transfer pilus assembly protein TraB -
MUK76_RS25840 (34557) 34557..35013 + 457 Protein_48 conjugal transfer pilus-stabilizing protein TraP -
MUK76_RS25845 (34982) 34982..35334 + 353 Protein_49 DUF2689 domain-containing protein -
MUK76_RS25850 (35327) 35327..35579 + 253 Protein_50 conjugal transfer protein TrbG -
MUK76_RS25855 (35576) 35576..36091 + 516 Protein_51 type IV conjugative transfer system lipoprotein TraV -
MUK76_RS25860 (36226) 36226..36446 + 221 Protein_52 conjugal transfer protein TraR -
MUK76_RS25865 (36439) 36439..36912 + 474 WP_000549566.1 hypothetical protein -
MUK76_RS25870 (36992) 36992..37210 + 219 WP_000556746.1 hypothetical protein -
MUK76_RS25875 (37575) 37575..40199 + 2625 Protein_55 type IV secretion system protein TraC -
MUK76_RS25880 (40196) 40196..40582 + 387 WP_000214084.1 type-F conjugative transfer system protein TrbI -
MUK76_RS25885 (40579) 40579..41210 + 632 Protein_57 type-F conjugative transfer system protein TraW -
MUK76_RS25890 (41207) 41207..42196 + 990 Protein_58 conjugal transfer pilus assembly protein TraU -
MUK76_RS25895 (42226) 42226..42531 + 306 WP_000224416.1 hypothetical protein -
MUK76_RS25900 (42540) 42540..43177 + 638 Protein_60 type-F conjugative transfer system pilin assembly protein TrbC -
MUK76_RS25905 (43174) 43174..45021 + 1848 Protein_61 type-F conjugative transfer system mating-pair stabilization protein TraN -
MUK76_RS25910 (45048) 45048..45304 + 257 Protein_62 conjugal transfer protein TrbE -
MUK76_RS25915 (45297) 45297..46034 + 738 Protein_63 type-F conjugative transfer system pilin assembly protein TraF -
MUK76_RS25920 (46048) 46048..46388 + 341 Protein_64 conjugal transfer protein TrbA -
MUK76_RS25925 (46784) 46784..47066 + 283 Protein_65 type-F conjugative transfer system pilin chaperone TraQ -
MUK76_RS25930 (47053) 47053..47596 + 544 Protein_66 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
MUK76_RS25935 (47526) 47526..47872 + 347 Protein_67 P-type conjugative transfer protein TrbJ -
MUK76_RS25940 (47853) 47853..48238 + 386 Protein_68 F-type conjugal transfer protein TrbF -
MUK76_RS25945 (48309) 48309..49304 + 996 Protein_69 conjugal transfer protein TraH -
MUK76_RS25950 (49277) 49277..49591 + 315 WP_231529599.1 hypothetical protein -
MUK76_RS25955 (49588) 49588..52404 + 2817 Protein_71 conjugal transfer mating-pair stabilization protein TraG -
MUK76_RS25960 (52419) 52419..52922 + 504 WP_000605510.1 hypothetical protein -
MUK76_RS25965 (52971) 52971..53684 + 714 WP_000989337.1 conjugal transfer complement resistance protein TraT -
MUK76_RS25970 (53887) 53887..54622 + 736 Protein_74 hypothetical protein -
MUK76_RS25975 (54673) 54673..57144 + 2472 Protein_75 type IV conjugative transfer system coupling protein TraD -
MUK76_RS25980 (57144) 57144..62414 + 5271 Protein_76 Multifunctional conjugation protein TraI Relaxase
MUK76_RS25985 (62434) 62434..63181 + 748 Protein_77 conjugal transfer pilus acetylase TraX -
MUK76_RS25990 (63236) 63236..63792 + 557 Protein_78 fertility inhibition protein FinO -
MUK76_RS25995 (63944) 63944..64147 + 204 WP_001336517.1 hypothetical protein -
MUK76_RS26000 (64899) 64899..65348 + 450 WP_115254630.1 thermonuclease family protein -
MUK76_RS26005 (65618) 65618..65836 + 219 WP_113365647.1 hypothetical protein -
MUK76_RS26010 (65989) 65989..66426 + 438 WP_000872609.1 hypothetical protein -
- (66521) 66521..66577 - 57 NuclAT_1 - -
- (66521) 66521..66577 - 57 NuclAT_1 - -
- (66521) 66521..66577 - 57 NuclAT_1 - -
- (66521) 66521..66577 - 57 NuclAT_1 - -
MUK76_RS26015 (66625) 66625..66774 + 150 WP_001336447.1 Hok/Gef family protein -
MUK76_RS26020 (67059) 67059..67316 + 258 WP_000084404.1 replication regulatory protein RepA -
MUK76_RS26025 (67551) 67551..67625 + 75 WP_001365705.1 RepA leader peptide Tap -
MUK76_RS26030 (67618) 67618..68472 + 855 Protein_86 incFII family plasmid replication initiator RepA -
MUK76_RS26035 (69411) 69411..70064 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
MUK76_RS26040 (70157) 70157..70414 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
MUK76_RS26045 (70347) 70347..70748 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
MUK76_RS26050 (70997) 70997..71412 + 416 Protein_90 IS1-like element IS1B family transposase -
MUK76_RS26055 (71448) 71448..71993 - 546 Protein_91 Tn3 family transposase TnpA_Tn3 Transposase
MUK76_RS26060 (72059) 72059..72762 - 704 Protein_92 IS6 family transposase IS15DI Transposase
MUK76_RS26065 (72897) 72897..72992 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
MUK76_RS26070 (73118) 73118..73854 + 737 Protein_94 rRNA adenine N-6-methyltransferase ARG
MUK76_RS26075 (74479) 74479..74928 + 450 WP_013362817.1 hypothetical protein -
MUK76_RS26080 (74889) 74889..75428 + 540 WP_244750116.1 60 kDa chaperonin VF
MUK76_RS26085 (75504) 75504..76913 + 1410 Protein_97 IS91 family transposase ISVsa3 Transposase
MUK76_RS26090 (77309) 77309..78013 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
MUK76_RS26095 (78078) 78078..78255 + 178 Protein_99 IS1380 family transposase -
MUK76_RS26100 (78503) 78503..79373 + 871 Protein_100 Beta-lactamase CTX-M-97 ARG
MUK76_RS26105 (79408) 79408..80375 + 968 Protein_101 IS5-like element IS903B family transposase -
MUK76_RS26110 (80432) 80432..81527 + 1096 Protein_102 TonB-dependent receptor -
MUK76_RS26115 (81593) 81593..81904 - 312 Protein_103 Tn3 family transposase TnpA_Tn3 Transposase
MUK76_RS26120 (81964) 81964..82665 + 702 WP_244750108.1 IS6 family transposase IS15DI Transposase
MUK76_RS26125 (82718) 82718..83224 + 507 Protein_105 DNA-binding domain-containing protein -
MUK76_RS26130 (83233) 83233..84093 + 861 WP_000493383.1 EamA family transporter -
MUK76_RS26135 (84125) 84125..85321 - 1197 Protein_107 tetracycline efflux MFS transporter Tet(A) -
MUK76_RS26140 (85427) 85427..86052 + 626 Protein_108 tetracycline resistance transcriptional repressor TetR(A) -
MUK76_RS26145 (86084) 86084..86320 - 237 WP_042005022.1 hypothetical protein -
MUK76_RS26150 (86374) 86374..87210 - 837 Protein_110 hypothetical protein ARG
MUK76_RS26155 (87210) 87210..88013 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
MUK76_RS26160 (88074) 88074..88889 - 816 WP_001043260.1 Dihydropteroate synthase ARG
MUK76_RS26165 (89195) 89195..89371 - 177 Protein_113 replication protein C, IncQ-type -
MUK76_RS26170 (89432) 89432..90136 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
MUK76_RS26175 (90258) 90258..91162 + 905 Protein_115 hypothetical protein ARG
MUK76_RS26180 (91159) 91159..92397 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
MUK76_RS26185 (92397) 92397..92981 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
MUK76_RS26190 (93474) 93474..94235 - 762 Protein_118 IS6-like element IS6100 family transposase -
MUK76_RS26195 (94353) 94353..94418 - 66 Protein_119 EAL domain-containing protein -
MUK76_RS26200 (94462) 94462..94763 - 302 Protein_120 hypothetical protein Relaxase
MUK76_RS26205 (94774) 94774..95977 - 1204 Protein_121 chromate efflux transporter -
MUK76_RS26210 (96133) 96133..96336 - 204 WP_000376616.1 hypothetical protein -
MUK76_RS26215 (96464) 96464..97303 - 840 WP_000259031.1 Dihydropteroate synthase ARG
MUK76_RS26220 (97297) 97297..97644 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
MUK76_RS26225 (97850) 97850..98638 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
MUK76_RS26230 (98769) 98769..99240 - 472 Protein_126 trimethoprim-resistant dihydrofolate reductase DfrA17 -
MUK76_RS26235 (99393) 99393..100136 + 744 Protein_127 IS91 family transposase ISAzo26 Transposase
MUK76_RS26240 (100195) 100195..100898 + 704 Protein_128 IS6 family transposase IS15DI Transposase
MUK76_RS26245 (100948) 100948..101202 - 255 Protein_129 IS1 family transposase IS1R Transposase
MUK76_RS26250 (101197) 101197..101876 - 680 Protein_130 IS1 family transposase IS1R Transposase
MUK76_RS26255 (102076) 102076..102189 + 114 Protein_131 IS6 family transposase IS15DI Transposase
MUK76_RS26260 (102332) 102332..102496 + 165 Protein_132 DsbA family protein -
MUK76_RS26265 (102486) 102486..102991 + 506 Protein_133 protein disulfide oxidoreductase -
MUK76_RS26270 (103228) 103228..103989 + 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
MUK76_RS26275 (104094) 104094..104797 - 704 Protein_135 IS6 family transposase IS15DI Transposase
MUK76_RS26280 (105162) 105162..107047 + 1886 Protein_136 FTR1 family protein -
MUK76_RS26285 (107088) 107088..107615 + 528 WP_000178050.1 iron transporter -
MUK76_RS26290 (107719) 107719..109097 + 1379 Protein_138 Fe-S-containing protein -
MUK76_RS26295 (109100) 109100..110380 + 1281 Protein_139 ABC transporter permease -
MUK76_RS26300 (110370) 110370..111504 + 1135 Protein_140 ABC transporter permease -
MUK76_RS26305 (111509) 111509..112203 + 695 Protein_141 Lipoprotein-releasing system ATP-binding protein LolD VF
MUK76_RS26310 (112190) 112190..112676 + 487 Protein_142 TlpA disulfide reductase family protein -
MUK76_RS26315 (112701) 112701..113186 + 486 WP_000874189.1 hypothetical protein -
MUK76_RS26320 (113307) 113307..113940 + 634 Protein_144 histidine-type phosphatase -
MUK76_RS26325 (114090) 114090..114263 - 174 Protein_145 IS5 family transposase ISKpn26 Transposase
MUK76_RS26330 (114264) 114264..114578 - 315 Protein_146 IS5 family transposase ISKpn26 Transposase
MUK76_RS26335 (115251) 115251..115987 - 737 Protein_147 IS3 family transposase IS629 Transposase
MUK76_RS26340 (116088) 116088..116353 + 266 Protein_148 hypothetical protein -
MUK76_RS26345 (116343) 116343..116858 + 516 Protein_149 hypothetical protein -
MUK76_RS26350 (116878) 116878..117184 - 307 Protein_150 DUF6404 family protein -
MUK76_RS26355 (117251) 117251..117424 + 174 WP_244750109.1 hypothetical protein -
MUK76_RS26360 (119118) 119118..119743 + 626 Protein_152 replication initiation protein -
MUK76_RS26365 (120117) 120117..120989 + 873 Protein_153 ChaN family lipoprotein -
MUK76_RS26370 (120997) 120997..121359 + 363 WP_244750110.1 hypothetical protein -
MUK76_RS26375 (121437) 121437..121772 + 336 WP_231553384.1 energy transducer TonB -
MUK76_RS26380 (122176) 122176..122547 + 372 WP_244750115.1 putative TonB-dependent receptor VF
MUK76_RS26385 (122688) 122688..124199 + 1512 WP_244750111.1 TonB-dependent receptor -
MUK76_RS26390 (124268) 124268..125443 + 1176 WP_001020413.1 putative protein YncE VF
MUK76_RS26395 (125966) 125966..126269 - 304 Protein_159 IS91 family transposase ISSbo1 Transposase
MUK76_RS26400 (126295) 126295..127034 + 740 Protein_160 IS3 family transposase IS629 Transposase
MUK76_RS26405 (127706) 127706..129214 + 1509 WP_001189113.1 group II intron reverse transcriptase/maturase -
MUK76_RS26410 (129296) 129296..129634 + 339 Protein_162 IS3 family transposase IS629 Transposase
MUK76_RS26415 (129776) 129776..129991 + 216 WP_001434052.1 IS3 family transposase IS629 Transposase
MUK76_RS26420 (130113) 130113..130460 + 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
MUK76_RS26425 (130509) 130509..131448 + 940 Protein_165 IS66 family transposase ISEc8 Transposase
MUK76_RS26430 (131534) 131534..132556 + 1023 WP_001310017.1 IS21 family transposase IS100kyp Transposase
MUK76_RS26435 (132553) 132553..133333 + 781 Protein_167 IS21 family transposase IS100kyp Transposase
MUK76_RS26440 (133401) 133401..134009 + 609 Protein_168 IS66 family transposase ISEc22 Transposase
MUK76_RS26445 (134072) 134072..134861 - 790 Protein_169 DUF4198 domain-containing protein -
MUK76_RS26450 (134868) 134868..136824 - 1957 Protein_170 TonB-dependent receptor -
MUK76_RS26455 (137110) 137110..137534 + 425 Protein_171 IS3 family transposase IS2 Transposase
MUK76_RS26460 (138188) 138188..138339 + 152 Protein_172 hypothetical protein VF
MUK76_RS26465 (138820) 138820..138963 + 144 Protein_173 IS3 family transposase -
MUK76_RS26470 (140718) 140718..140906 + 189 WP_001309252.1 hypothetical protein -
MUK76_RS26475 (141027) 141027..141766 + 740 Protein_175 tyrosine-type recombinase/integrase -
MUK76_RS26480 (142007) 142007..142978 - 972 WP_244750112.1 RepB family plasmid replication initiator protein -
MUK76_RS26485 (144199) 144199..144789 - 591 WP_244750113.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance