MGE detailed information

MGE type: Conjugative plasmid        MGE length: 161701 bp
Accession: NZ_CP085061        Location: 1..161701         Organism: Escherichia coli strain P30_L1_05.20       Replicon: plasmid pNDM_P30_L1_05.20


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH369_RS23455 (1) 1..978 + 978 WP_000361615.1 RepB family plasmid replication initiator protein -
LH369_RS23460 (1256) 1256..1996 - 741 WP_001066941.1 tyrosine-type recombinase/integrase -
LH369_RS23465 (2117) 2117..2299 - 183 WP_050488504.1 hypothetical protein -
LH369_RS23470 (2366) 2366..2656 - 291 Protein_3 type II toxin-antitoxin system RelE/ParE family toxin -
LH369_RS23475 (2643) 2643..2899 - 257 Protein_4 type II toxin-antitoxin system ParD family antitoxin -
LH369_RS23480 (3431) 3431..4600 + 1170 WP_001403369.1 hypothetical protein -
LH369_RS23485 (4633) 4633..4761 + 129 Protein_6 IS481 family transposase -
LH369_RS23490 (4886) 4886..5089 - 204 Protein_7 hypothetical protein -
LH369_RS23495 (5195) 5195..5470 - 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LH369_RS23500 (5470) 5470..5754 - 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LH369_RS23505 (6359) 6359..7111 + 753 WP_001403368.1 IclR family transcriptional regulator -
LH369_RS23510 (7157) 7157..8122 - 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
LH369_RS23515 (8155) 8155..8535 - 381 WP_000710783.1 Rid family detoxifying hydrolase -
LH369_RS23520 (8560) 8560..9450 - 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
LH369_RS23525 (9804) 9804..10370 + 567 Protein_14 zinc-binding dehydrogenase -
LH369_RS23530 (10501) 10501..11379 + 879 WP_000338039.1 sugar ABC transporter permease -
LH369_RS23535 (11369) 11369..12256 + 888 WP_001271561.1 carbohydrate ABC transporter permease -
LH369_RS23540 (12267) 12267..13091 + 825 WP_000922702.1 phosphodiesterase -
LH369_RS23545 (13097) 13097..14170 + 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
LH369_RS23550 (14163) 14163..15473 + 1311 WP_000476108.1 ABC transporter substrate-binding protein -
LH369_RS23555 (15532) 15532..15840 - 309 Protein_20 IS4 family transposase ISEc13 Transposase
LH369_RS23560 (15917) 15917..16132 - 216 Protein_21 transposase -
LH369_RS23565 (16187) 16187..16926 + 740 Protein_22 IS3 family transposase IS629 Transposase
LH369_RS24910 (17438) 17438..17560 + 123 WP_001406634.1 hypothetical protein -
LH369_RS23570 (17599) 17599..19107 + 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
LH369_RS23575 (19191) 19191..19671 + 481 Protein_25 IS3 family transposase IS629 Transposase
LH369_RS23580 (19724) 19724..20761 - 1038 WP_032248218.1 LacI family DNA-binding transcriptional regulator -
LH369_RS23585 (21297) 21297..22364 + 1068 WP_032248209.1 cellulase family glycosylhydrolase -
LH369_RS23590 (22482) 22482..23846 + 1365 WP_077758488.1 MFS transporter -
LH369_RS23595 (24226) 24226..25734 - 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
LH369_RS24915 (25773) 25773..25895 - 123 WP_001406634.1 hypothetical protein -
LH369_RS23600 (26407) 26407..27146 - 740 Protein_31 IS3 family transposase IS629 Transposase
LH369_RS23605 (27253) 27253..27387 - 135 Protein_32 hypothetical protein -
LH369_RS23610 (27620) 27620..28798 + 1179 WP_001403462.1 MalY/PatB family protein -
LH369_RS23615 (28791) 28791..30242 + 1452 WP_001403463.1 Na+/H+ antiporter NhaC -
LH369_RS23620 (30317) 30317..30450 - 134 Protein_35 phosphate-starvation-inducible protein PsiE -
LH369_RS23625 (30499) 30499..32118 - 1620 WP_077885511.1 ISL3 family transposase ISEc38 Transposase
LH369_RS23630 (32215) 32215..32722 + 508 Protein_37 IS3 family transposase IS2 Transposase
LH369_RS23635 (32798) 32798..32977 + 180 Protein_38 polysaccharide deacetylase family protein -
LH369_RS23640 (32984) 32984..33364 - 381 WP_032269702.1 aspartate 1-decarboxylase -
LH369_RS23645 (33637) 33637..33768 + 132 Protein_40 Rpn family recombination-promoting nuclease/putative transposase -
LH369_RS23650 (33966) 33966..35360 + 1395 WP_001402894.1 MFS transporter -
LH369_RS23655 (35466) 35466..36497 + 1032 WP_001402895.1 LacI family DNA-binding transcriptional regulator -
LH369_RS23660 (36472) 36472..37491 + 1020 WP_024200979.1 nucleoside hydrolase -
LH369_RS23665 (37555) 37555..38268 + 714 WP_033553771.1 Protein SapB VF
LH369_RS23670 (38459) 38459..39163 + 705 WP_098986935.1 IS6 family transposase IS26 Transposase
LH369_RS23675 (39317) 39317..39487 + 171 Protein_46 DsbA family protein -
LH369_RS23680 (39477) 39477..39983 + 507 WP_000949451.1 protein disulfide oxidoreductase -
LH369_RS23690 (40996) 40996..41757 + 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
LH369_RS23695 (42104) 42104..43990 + 1887 WP_001332815.1 FTR1 family protein -
LH369_RS23700 (44031) 44031..44558 + 528 WP_000178050.1 iron transporter -
LH369_RS23705 (44662) 44662..46041 + 1380 WP_033553992.1 Fe-S-containing protein -
LH369_RS23710 (46044) 46044..47327 + 1284 WP_000964653.1 ABC transporter permease -
LH369_RS23715 (47317) 47317..48447 + 1131 WP_000729219.1 ABC transporter permease -
LH369_RS23720 (48452) 48452..49147 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
LH369_RS23725 (49134) 49134..49619 + 486 WP_001554949.1 TlpA disulfide reductase family protein -
LH369_RS23730 (49644) 49644..50129 + 486 WP_000874189.1 hypothetical protein -
LH369_RS23735 (50251) 50251..50511 + 261 Protein_58 bifunctional glucose-1-phosphatase/inositol phosphatase -
LH369_RS23740 (50565) 50565..51269 - 705 WP_098986935.1 IS6 family transposase IS26 Transposase
LH369_RS23745 (51448) 51448..51798 - 351 WP_000454193.1 DUF3330 domain-containing protein -
LH369_RS23750 (52001) 52001..53014 - 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
LH369_RS23755 (53159) 53159..53656 + 498 WP_001083725.1 Dihydrofolate reductase ARG
LH369_RS23760 (53768) 53768..54058 + 291 WP_001336345.1 DUF1010 domain-containing protein -
LH369_RS23765 (54064) 54064..54902 + 839 Protein_64 Streptomycin 3''-adenylyltransferase ARG
LH369_RS23770 (55019) 55019..55366 + 348 WP_000679427.1 Endonuclease YhcR ARG
LH369_RS23775 (55360) 55360..56199 + 840 WP_000259031.1 hypothetical protein ARG
LH369_RS23780 (56604) 56604..58145 + 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
LH369_RS23785 (58458) 58458..58832 + 375 Protein_68 protein-disulfide reductase DsbD family protein -
LH369_RS23790 (58932) 58932..59489 + 558 Protein_69 twin-arginine translocation (TAT) pathway signal sequence domain protein -
LH369_RS23795 (59500) 59500..60138 - 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
LH369_RS23800 (60143) 60143..60508 - 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
LH369_RS23805 (60512) 60512..61324 - 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
LH369_RS23810 (61425) 61425..61718 - 294 Protein_73 IS30 family transposase -
LH369_RS23815 (61883) 61883..62587 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LH369_RS23820 (62781) 62781..63131 - 351 Protein_75 60 kDa chaperonin VF
LH369_RS23825 (63194) 63194..63742 + 549 WP_014342204.1 cation:proton antiporter -
LH369_RS23830 (63823) 63823..64578 - 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
LH369_RS23835 (64748) 64748..65608 - 861 WP_000027057.1 Beta-lactamase TEM ARG
LH369_RS23840 (65791) 65791..66348 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
LH369_RS23845 (66650) 66650..67414 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
LH369_RS23850 (67907) 67907..68491 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
LH369_RS23855 (68491) 68491..69729 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
LH369_RS23860 (69726) 69726..70640 - 915 WP_023063803.1 hypothetical protein ARG
LH369_RS23865 (70762) 70762..71466 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LH369_RS23870 (71601) 71601..71696 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
LH369_RS23875 (71822) 71822..72559 + 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
LH369_RS23880 (73189) 73189..73638 + 450 WP_013362817.1 hypothetical protein -
LH369_RS23885 (73599) 73599..73940 + 342 WP_023909256.1 60 kDa chaperonin 2 VF
LH369_RS23890 (74215) 74215..75606 + 1392 Protein_89 IS91 family transposase ISVsa3 Transposase
LH369_RS23895 (75660) 75660..76364 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LH369_RS23900 (76430) 76430..76975 + 546 Protein_91 Tn3 family transposase TnpA_Tn3 Transposase
LH369_RS23905 (77011) 77011..77426 - 416 Protein_92 IS1-like element IS1B family transposase -
LH369_RS23910 (77675) 77675..78076 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LH369_RS23915 (78009) 78009..78266 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LH369_RS23920 (78359) 78359..79012 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LH369_RS23925 (79952) 79952..80809 - 858 WP_032265352.1 incFII family plasmid replication initiator RepA -
LH369_RS23935 (80828) 80828..81007 - 180 Protein_97 plasmid copy control protein CopA -
LH369_RS23940 (81114) 81114..81368 - 255 WP_000083830.1 replication regulatory protein RepA -
LH369_RS23945 (81608) 81608..82198 - 591 WP_000766807.1 DUF2726 domain-containing protein -
LH369_RS23950 (82236) 82236..82445 - 210 WP_001298565.1 hemolysin expression modulator Hha -
LH369_RS23955 (82547) 82547..83224 + 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
LH369_RS23960 (83224) 83224..83571 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
LH369_RS23965 (83591) 83591..85162 + 1572 WP_029392005.1 IS66 family transposase ISCro1 Transposase
LH369_RS23970 (85198) 85198..85659 - 462 WP_001233838.1 thermonuclease family protein -
LH369_RS23975 (85904) 85904..86116 - 213 WP_001309245.1 ANR family transcriptional regulator -
LH369_RS23980 (86245) 86245..86805 - 561 WP_000139323.1 fertility inhibition protein FinO -
LH369_RS23985 (86908) 86908..87768 - 861 WP_000704523.1 putative protein YcjY VF
LH369_RS23990 (87827) 87827..88573 - 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
LH369_RS23995 (88593) 88593..93863 - 5271 WP_000948354.1 Multifunctional conjugation protein TraI Relaxase
LH369_RS24000 (93863) 93863..95833 - 1971 Protein_110 Coupling protein TraD VF
LH369_RS24005 (95919) 95919..96665 - 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
LH369_RS24010 (96680) 96680..98221 - 1542 WP_002431311.1 IS21 family transposase ISEc12 Transposase
LH369_RS24015 (98414) 98414..98737 - 324 Protein_113 conjugal transfer protein TraD -
LH369_RS24020 (98788) 98788..99525 - 738 WP_000199905.1 hypothetical protein -
LH369_RS24025 (99728) 99728..100459 - 732 WP_000850429.1 conjugal transfer complement resistance protein TraT -
LH369_RS24030 (100490) 100490..100993 - 504 WP_000605509.1 hypothetical protein -
LH369_RS24035 (101008) 101008..103830 - 2823 WP_069067318.1 conjugal transfer mating-pair stabilization protein TraG -
LH369_RS24040 (103827) 103827..105200 - 1374 WP_001137364.1 conjugal transfer pilus assembly protein TraH -
LH369_RS24045 (105187) 105187..105579 - 393 WP_001744736.1 F-type conjugal transfer protein TrbF -
LH369_RS24050 (105560) 105560..105901 - 342 WP_001448115.1 P-type conjugative transfer protein TrbJ -
LH369_RS24055 (105831) 105831..106376 - 546 WP_000059832.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LH369_RS24060 (106363) 106363..106647 - 285 WP_000623730.1 type-F conjugative transfer system pilin chaperone TraQ -
LH369_RS24065 (106774) 106774..107112 - 339 WP_069067319.1 conjugal transfer protein TrbA -
LH369_RS24070 (107128) 107128..107871 - 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
LH369_RS24075 (107864) 107864..108121 - 258 WP_000864329.1 conjugal transfer protein TrbE -
LH369_RS24080 (108148) 108148..109998 - 1851 WP_063610838.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LH369_RS24085 (109995) 109995..110633 - 639 WP_127525951.1 type-F conjugative transfer system pilin assembly protein TrbC -
LH369_RS24090 (110642) 110642..110947 - 306 WP_069067320.1 hypothetical protein -
LH369_RS24095 (110977) 110977..111969 - 993 WP_069067321.1 conjugal transfer pilus assembly protein TraU -
LH369_RS24100 (111966) 111966..112598 - 633 WP_001203727.1 type-F conjugative transfer system protein TraW -
LH369_RS24105 (112595) 112595..112981 - 387 WP_000214082.1 type-F conjugative transfer system protein TrbI -
LH369_RS24110 (112978) 112978..115608 - 2631 WP_069067322.1 type IV secretion system protein TraC -
LH369_RS24115 (115735) 115735..116097 - 363 WP_069067323.1 hypothetical protein -
LH369_RS24120 (116125) 116125..116340 - 216 WP_000556747.1 hypothetical protein -
LH369_RS24125 (116420) 116420..116896 - 477 WP_069067324.1 hypothetical protein -
LH369_RS24130 (116960) 116960..117657 + 698 WP_094096600.1 IS1 family transposase IS1A Transposase
LH369_RS24135 (117668) 117668..117886 - 219 WP_074447208.1 conjugal transfer protein TraR -
LH369_RS24140 (118021) 118021..118536 - 516 WP_001681800.1 type IV conjugative transfer system lipoprotein TraV -
LH369_RS24145 (118533) 118533..118853 - 321 WP_069067340.1 conjugal transfer protein TrbD -
LH369_RS24150 (118840) 118840..119406 - 567 WP_001526038.1 conjugal transfer pilus-stabilizing protein TraP -
LH369_RS24155 (119396) 119396..120847 - 1452 WP_098986942.1 F-type conjugal transfer pilus assembly protein TraB -
LH369_RS24160 (120847) 120847..121575 - 729 WP_001230772.1 type-F conjugative transfer system secretin TraK -
LH369_RS24165 (121562) 121562..122128 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
LH369_RS24170 (122150) 122150..122461 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LH369_RS24175 (122466) 122466..122828 - 363 WP_069067339.1 type IV conjugative transfer system pilin TraA -
LH369_RS24180 (122862) 122862..123089 - 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
LH369_RS24185 (123177) 123177..123869 - 693 WP_069067593.1 PAS domain-containing protein -
LH369_RS24190 (124063) 124063..124446 - 384 WP_069067309.1 conjugal transfer relaxosome DNA-binding protein TraM -
LH369_RS24195 (124777) 124777..125379 + 603 WP_000243712.1 hypothetical protein VF
LH369_RS24200 (125676) 125676..126497 - 822 WP_001234469.1 DUF932 domain-containing protein -
LH369_RS24205 (126616) 126616..126903 - 288 WP_033553574.1 hypothetical protein -
LH369_RS24210 (126928) 126928..127134 - 207 WP_033553572.1 hypothetical protein -
LH369_RS24215 (127204) 127204..127376 + 173 Protein_153 hypothetical protein -
LH369_RS24220 (127374) 127374..127604 - 231 WP_001426396.1 hypothetical protein -
LH369_RS24225 (127824) 127824..127949 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LH369_RS24230 (127891) 127891..128040 - 150 Protein_156 plasmid maintenance protein Mok -
- (128026) 128026..128250 - 225 NuclAT_0 - -
- (128026) 128026..128250 - 225 NuclAT_0 - -
- (128026) 128026..128250 - 225 NuclAT_0 - -
- (128026) 128026..128250 - 225 NuclAT_0 - -
LH369_RS24235 (128062) 128062..128250 + 189 WP_001299721.1 hypothetical protein -
LH369_RS24240 (128219) 128219..128981 - 763 Protein_158 plasmid SOS inhibition protein A -
LH369_RS24245 (128978) 128978..129412 - 435 WP_001470779.1 conjugation system SOS inhibitor PsiB -
LH369_RS24250 (129467) 129467..131425 - 1959 WP_033553971.1 ParB/RepB/Spo0J family partition protein -
LH369_RS24255 (131491) 131491..131724 - 234 Protein_161 DUF905 domain-containing protein -
LH369_RS24260 (131787) 131787..132326 - 540 WP_033553973.1 single-stranded DNA-binding protein -
LH369_RS24265 (132352) 132352..132558 - 207 WP_050516944.1 hypothetical protein -
LH369_RS24270 (132798) 132798..133052 - 255 WP_001366172.1 hypothetical protein -
LH369_RS24275 (132968) 132968..133177 - 210 WP_032151920.1 hypothetical protein -
LH369_RS24280 (133203) 133203..133766 - 564 WP_001315564.1 class I SAM-dependent methyltransferase -
LH369_RS24285 (133814) 133814..135175 - 1362 WP_033554272.1 DUF3560 domain-containing protein -
LH369_RS24290 (135227) 135227..135457 - 231 WP_000218651.1 hypothetical protein -
LH369_RS24295 (136122) 136122..136277 - 156 WP_001744062.1 hypothetical protein -
LH369_RS24300 (136491) 136491..136682 - 192 WP_033553997.1 hypothetical protein -
LH369_RS24305 (136679) 136679..137101 - 423 WP_069067308.1 DUF1380 family protein -
LH369_RS24310 (137148) 137148..137573 - 426 WP_001198928.1 antirestriction protein -
LH369_RS24315 (138032) 138032..139144 + 1113 WP_001300563.1 IS4 family transposase IS421 Transposase
LH369_RS24320 (139335) 139335..140111 - 777 WP_001005023.1 hypothetical protein -
LH369_RS24325 (140157) 140157..140624 - 468 WP_224219389.1 DUF1380 family protein -
LH369_RS24330 (140605) 140605..140826 - 222 WP_001104879.1 hypothetical protein -
LH369_RS24335 (140827) 140827..141510 - 684 WP_000086148.1 DNA methylase -
LH369_RS24340 (141586) 141586..141897 - 312 WP_033554393.1 hypothetical protein -
LH369_RS24345 (141894) 141894..142795 - 902 Protein_179 DUF1281 domain-containing protein -
LH369_RS24350 (143489) 143489..144460 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
LH369_RS24355 (144460) 144460..145626 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
LH369_RS24360 (146214) 146214..146969 - 756 WP_000852146.1 replication initiation protein RepE -
LH369_RS24365 (147743) 147743..148549 - 807 WP_000016982.1 site-specific integrase -
LH369_RS24370 (148550) 148550..148855 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LH369_RS24375 (148857) 148857..149075 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LH369_RS24380 (149655) 149655..150743 + 1089 WP_033554392.1 transcriptional repressor PifC -
LH369_RS24385 (150745) 150745..152970 + 2226 WP_033554391.1 P-loop NTPase fold protein -
LH369_RS24390 (153020) 153020..153919 - 900 WP_032173297.1 nucleotide-binding protein -
LH369_RS24395 (153909) 153909..154199 - 291 WP_032173296.1 hypothetical protein -
LH369_RS24400 (155029) 155029..156050 - 1022 Protein_190 IS110 family transposase ISSm1 Transposase
LH369_RS24405 (157681) 157681..158298 + 618 WP_033554390.1 hypothetical protein -
LH369_RS24410 (158328) 158328..159938 - 1611 Protein_192 IS66 family transposase ISEc23 Transposase
LH369_RS24415 (159969) 159969..160319 - 351 WP_033554029.1 IS66 family transposase ISEc23 Transposase
LH369_RS24420 (160316) 160316..160741 - 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
LH369_RS24425 (160823) 160823..161050 - 228 WP_072023938.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance