MGE detailed information
MGE type: Conjugative plasmid MGE length: 91844 bp
Accession: NZ_CP080129 Location: 1..91844 Organism: Escherichia coli strain PK8568 Replicon: plasmid pPK8568-tetX
Accession: NZ_CP080129 Location: 1..91844 Organism: Escherichia coli strain PK8568 Replicon: plasmid pPK8568-tetX
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZY03_RS24070 () | 251..679 | - | 429 | WP_232377371.1 | Methyl-accepting chemotaxis protein McpU | VF |
| KZY03_RS24075 () | 676..3708 | - | 3033 | WP_039022048.1 | Tn3 family transposase ISPsy42 | Transposase |
| KZY03_RS24080 () | 3712..3810 | - | 99 | Protein_2 | helix-turn-helix domain-containing protein | - |
| KZY03_RS24085 () | 3863..4567 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KZY03_RS24090 () | 4614..6122 | - | 1509 | WP_219795205.1 | IS91 family transposase ISVsa3 | Transposase |
| KZY03_RS24095 () | 6461..7618 | - | 1158 | WP_094309310.1 | Kynurenine 3-monooxygenase | ARG |
| KZY03_RS24100 () | 7608..8525 | - | 918 | WP_094309312.1 | macrolide hydrolase EstT | - |
| KZY03_RS24105 () | 9237..10730 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| KZY03_RS24110 () | 10842..11147 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| KZY03_RS24115 () | 11175..12389 | - | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| KZY03_RS24120 () | 12606..13169 | - | 564 | WP_232379271.1 | DUF3363 domain-containing protein | - |
| KZY03_RS24125 () | 13138..13242 | - | 105 | WP_219805143.1 | DUF3363 domain-containing protein | - |
| KZY03_RS24130 () | 13586..14290 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KZY03_RS24135 () | 14596..15045 | + | 450 | WP_023281052.1 | helix-turn-helix domain-containing protein | - |
| KZY03_RS24140 () | 15024..15173 | + | 150 | WP_152930637.1 | hypothetical protein | - |
| KZY03_RS24145 () | 15693..16232 | + | 540 | WP_039021305.1 | hypothetical protein | - |
| KZY03_RS24150 () | 16243..16692 | + | 450 | WP_039021304.1 | hypothetical protein | - |
| KZY03_RS24155 () | 16676..17218 | + | 543 | WP_039021303.1 | hypothetical protein | - |
| KZY03_RS24160 () | 17290..17736 | + | 447 | WP_210388693.1 | hypothetical protein | - |
| KZY03_RS24165 () | 17727..17930 | + | 204 | WP_001567330.1 | hypothetical protein | - |
| KZY03_RS24170 () | 18179..20227 | + | 2049 | WP_023281053.1 | site-specific DNA-methyltransferase | - |
| KZY03_RS24175 () | 20232..22868 | + | 2637 | WP_023281054.1 | DEAD/DEAH box helicase family protein | - |
| KZY03_RS24180 () | 22911..23003 | - | 93 | Protein_22 | tRNA modification GTPase | - |
| KZY03_RS24185 () | 23152..24012 | - | 861 | WP_015058868.1 | Beta-lactamase TEM | ARG |
| KZY03_RS24190 () | 24147..24851 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KZY03_RS24195 () | 25667..25915 | + | 249 | Protein_25 | IS1380 family transposase ISEcp1 | Transposase |
| KZY03_RS25175 () | 25918..26004 | + | 87 | Protein_26 | hypothetical protein | - |
| KZY03_RS24200 () | 26035..26376 | + | 342 | WP_004202492.1 | Multiple antibiotic resistance protein MarA | VF |
| KZY03_RS25180 () | 26394..26618 | - | 225 | WP_232379272.1 | DUF1158 domain-containing protein | - |
| KZY03_RS24205 () | 26595..26897 | - | 303 | Protein_29 | hypothetical protein | - |
| KZY03_RS24210 () | 26935..27144 | - | 210 | Protein_30 | IS6 family transposase | - |
| KZY03_RS24215 () | 27210..28724 | + | 1515 | Protein_31 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KZY03_RS24220 () | 28793..29677 | + | 885 | WP_001345827.1 | hypothetical protein | - |
| KZY03_RS24225 () | 29673..29842 | + | 170 | Protein_33 | resolvase | - |
| KZY03_RS24230 () | 29849..30016 | - | 168 | WP_001430249.1 | hypothetical protein | - |
| KZY03_RS24235 () | 30188..32863 | - | 2676 | WP_015059139.1 | hypothetical protein | - |
| KZY03_RS24240 () | 33166..34167 | + | 1002 | WP_000138753.1 | DUF4238 domain-containing protein | - |
| KZY03_RS24245 () | 34392..34802 | - | 411 | WP_001430251.1 | hypothetical protein | - |
| KZY03_RS24250 () | 34963..35313 | - | 351 | WP_001430247.1 | plasmid partitioning/stability family protein | - |
| KZY03_RS24255 () | 35316..36278 | - | 963 | WP_000959875.1 | plasmid segregation protein ParM | - |
| KZY03_RS24260 () | 36410..36718 | + | 309 | WP_039021875.1 | hypothetical protein | - |
| KZY03_RS24265 () | 36795..37478 | + | 684 | WP_000085889.1 | DNA methylase | - |
| KZY03_RS24270 () | 37479..37700 | + | 222 | WP_001104902.1 | hypothetical protein | - |
| KZY03_RS24275 () | 37594..38147 | + | 554 | Protein_43 | DUF1380 family protein | - |
| KZY03_RS24280 () | 38192..38962 | + | 771 | WP_001006207.1 | hypothetical protein | - |
| KZY03_RS24285 () | 39322..39747 | + | 426 | WP_001470882.1 | antirestriction protein | - |
| KZY03_RS24290 () | 39794..40216 | + | 423 | WP_000271684.1 | DUF1380 family protein | - |
| KZY03_RS24295 () | 40213..40404 | + | 192 | WP_039021874.1 | hypothetical protein | - |
| KZY03_RS24300 () | 41441..41671 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| KZY03_RS24305 () | 41723..43084 | + | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| KZY03_RS24310 () | 43130..43693 | + | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| KZY03_RS25185 () | 43693..43953 | + | 261 | WP_021536188.1 | hypothetical protein | - |
| KZY03_RS24315 () | 43845..44123 | + | 279 | WP_072127934.1 | hypothetical protein | - |
| KZY03_RS24320 () | 44364..44570 | + | 207 | WP_000275858.1 | hypothetical protein | - |
| KZY03_RS24325 () | 44596..45135 | + | 540 | WP_001825195.1 | single-stranded DNA-binding protein | - |
| KZY03_RS24330 () | 45198..45431 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| KZY03_RS24335 () | 45497..47455 | + | 1959 | WP_001825193.1 | ParB/RepB/Spo0J family partition protein | - |
| KZY03_RS24340 () | 47510..47944 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| KZY03_RS24345 () | 47941..48703 | + | 763 | Protein_58 | plasmid SOS inhibition protein A | - |
| KZY03_RS24350 () | 48672..48860 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 48672..48896 | + | 225 | NuclAT_0 | - | - |
| - () | 48672..48896 | + | 225 | NuclAT_0 | - | - |
| - () | 48672..48896 | + | 225 | NuclAT_0 | - | - |
| - () | 48672..48896 | + | 225 | NuclAT_0 | - | - |
| - | 48829..48894 | - | 66 | - | - | Antitoxin Detail |
| KZY03_RS25190 () | 48882..49031 | + | 150 | Protein_60 | plasmid maintenance protein Mok | - |
| KZY03_RS24355 () | 48973..49098 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KZY03_RS25195 () | 49318..49548 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| KZY03_RS25200 () | 49546..49719 | - | 174 | Protein_63 | hypothetical protein | - |
| KZY03_RS25205 () | 49789..49995 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| KZY03_RS24360 () | 50020..50307 | + | 288 | WP_000107544.1 | hypothetical protein | - |
| KZY03_RS24365 () | 50428..51249 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KZY03_RS24370 () | 51546..52193 | - | 648 | WP_031943493.1 | hypothetical protein | VF |
| KZY03_RS24375 () | 52470..52853 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KZY03_RS24380 () | 53044..53730 | + | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| KZY03_RS24385 () | 53824..54051 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| KZY03_RS24390 () | 54085..54444 | + | 360 | WP_210388694.1 | type IV conjugative transfer system pilin TraA | - |
| KZY03_RS24395 () | 54459..54770 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KZY03_RS24400 () | 54792..55358 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KZY03_RS24405 () | 55345..56073 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KZY03_RS24410 () | 56073..57500 | + | 1428 | WP_011117353.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KZY03_RS24415 () | 57490..58080 | + | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KZY03_RS24420 () | 58067..58387 | + | 321 | WP_220176225.1 | conjugal transfer protein TrbD | - |
| KZY03_RS24425 () | 58380..58631 | + | 252 | WP_032198481.1 | conjugal transfer protein TrbG | - |
| KZY03_RS24430 () | 58628..59143 | + | 516 | WP_039021963.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KZY03_RS24435 () | 59278..59499 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KZY03_RS24440 () | 59659..62286 | + | 2628 | WP_039021964.1 | type IV secretion system protein TraC | - |
| KZY03_RS24445 () | 62283..62669 | + | 387 | WP_000214096.1 | type-F conjugative transfer system protein TrbI | - |
| KZY03_RS24450 () | 62666..63298 | + | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| KZY03_RS24455 () | 63295..64287 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| KZY03_RS24460 () | 64313..64774 | + | 462 | WP_000277845.1 | hypothetical protein | - |
| KZY03_RS24465 () | 64804..65256 | + | 453 | WP_039021965.1 | hypothetical protein | - |
| KZY03_RS24470 () | 65284..65922 | + | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KZY03_RS24475 () | 65919..67727 | + | 1809 | WP_219805138.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KZY03_RS24480 () | 67754..68011 | + | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| KZY03_RS24485 () | 68004..68747 | + | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KZY03_RS24490 () | 68763..69110 | + | 348 | WP_001287902.1 | conjugal transfer protein TrbA | - |
| KZY03_RS24495 () | 69229..69513 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KZY03_RS24500 () | 69500..70045 | + | 546 | WP_039021966.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KZY03_RS24505 () | 69975..70337 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| KZY03_RS24510 () | 70337..71710 | + | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| KZY03_RS24515 () | 71707..74532 | + | 2826 | WP_001007045.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KZY03_RS24520 () | 74529..75038 | + | 510 | WP_031943494.1 | conjugal transfer entry exclusion protein TraS | - |
| KZY03_RS24525 () | 75052..75783 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| KZY03_RS24530 () | 76036..78234 | + | 2199 | WP_001496532.1 | type IV conjugative transfer system coupling protein TraD | - |
| KZY03_RS24535 () | 78243..78641 | - | 399 | WP_000911324.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KZY03_RS24540 () | 78641..78868 | - | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | - |
| KZY03_RS24545 () | 78950..84220 | + | 5271 | WP_039021708.1 | Multifunctional conjugation protein TraI | Relaxase |
| KZY03_RS24550 () | 84240..84986 | + | 747 | WP_219805142.1 | conjugal transfer pilus acetylase TraX | - |
| KZY03_RS24555 () | 85041..85601 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| KZY03_RS25210 () | 85732..85945 | + | 214 | Protein_105 | ANR family transcriptional regulator | - |
| KZY03_RS24560 () | 86231..86908 | + | 678 | WP_000392235.1 | PIN domain-containing protein | - |
| KZY03_RS24565 () | 87562..87774 | + | 213 | Protein_107 | ANR family transcriptional regulator | - |
| KZY03_RS24570 () | 88018..88479 | + | 462 | WP_015059120.1 | thermonuclease family protein | - |
| KZY03_RS24575 () | 88525..88734 | + | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| KZY03_RS24580 () | 88772..89345 | + | 574 | Protein_110 | DUF2726 domain-containing protein | - |
| KZY03_RS24585 () | 89585..89839 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| KZY03_RS24590 () | 90077..90151 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| KZY03_RS24595 () | 90144..91001 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|