MGE detailed information
MGE type: Conjugative plasmid MGE length: 153041 bp
Accession: NZ_CP076275 Location: 1..153041 Organism: Escherichia coli strain P393-F10 Replicon: plasmid pP393F10IncF
Accession: NZ_CP076275 Location: 1..153041 Organism: Escherichia coli strain P393-F10 Replicon: plasmid pP393F10IncF
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A7A10_RS25215 (2487) | 2487..3707 | + | 1221 | WP_000040077.1 | autotransporter strand-loop-strand O-heptosyltransferase | - |
| A7A10_RS25220 (3700) | 3700..8457 | + | 4758 | WP_257185959.1 | hypothetical protein | VF |
| A7A10_RS25225 (8765) | 8765..9034 | + | 270 | WP_000976359.1 | hypothetical protein | - |
| A7A10_RS25230 (9208) | 9208..9484 | - | 277 | Protein_4 | IS3 family transposase IS1351 | Transposase |
| A7A10_RS25235 (9891) | 9891..10727 | - | 837 | WP_000149836.1 | HTH-type transcriptional activator RhaR | VF |
| A7A10_RS25240 (11041) | 11041..12065 | - | 1025 | Protein_6 | IS3 family transposase | - |
| A7A10_RS25245 (12466) | 12466..13480 | + | 1015 | Protein_7 | integrase core domain-containing protein | - |
| A7A10_RS25255 (14282) | 14282..15229 | + | 948 | WP_001253824.1 | DMT family transporter | - |
| A7A10_RS25260 (15570) | 15570..15725 | + | 156 | Protein_9 | IS110 family transposase | - |
| A7A10_RS25265 (15986) | 15986..18994 | - | 3009 | Protein_10 | Tn3 family transposase ISEc63 | Transposase |
| A7A10_RS25270 (19158) | 19158..19709 | + | 552 | WP_053516395.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| A7A10_RS25275 (19960) | 19960..20163 | + | 204 | WP_072056988.1 | microcin B17 family TOMM | - |
| A7A10_RS25280 (20222) | 20222..21076 | + | 855 | WP_053516397.1 | McbB family protein | - |
| A7A10_RS25285 (21078) | 21078..21884 | + | 807 | WP_257115032.1 | SagB/ThcOx family dehydrogenase | - |
| A7A10_RS25290 (21877) | 21877..23064 | + | 1188 | WP_053516415.1 | YcaO-like family protein | - |
| A7A10_RS25295 (23074) | 23074..23799 | + | 726 | WP_160521638.1 | protein mcbE | - |
| A7A10_RS25300 (23796) | 23796..24524 | + | 729 | WP_065809879.1 | ATP-binding cassette domain-containing protein | - |
| A7A10_RS25305 (24528) | 24528..25088 | + | 561 | WP_064181638.1 | pentapeptide repeat-containing protein | - |
| A7A10_RS25310 (25639) | 25639..25890 | - | 252 | WP_001315600.1 | HTH domain-containing protein | - |
| A7A10_RS25315 (26328) | 26328..28505 | - | 2178 | WP_257115034.1 | UvrABC system protein A | VF |
| A7A10_RS25320 (28505) | 28505..29758 | - | 1254 | WP_257115056.1 | HlyD family secretion protein | - |
| A7A10_RS25325 (29842) | 29842..30450 | - | 609 | WP_257185963.1 | type II CAAX endopeptidase family protein | - |
| A7A10_RS25330 (30690) | 30690..31055 | - | 366 | WP_220393360.1 | hypothetical protein | - |
| A7A10_RS25335 (31188) | 31188..31841 | - | 654 | WP_257115036.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| A7A10_RS25340 (32010) | 32010..34997 | + | 2988 | WP_257185964.1 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| A7A10_RS25345 (35596) | 35596..36870 | + | 1275 | WP_257115038.1 | HlyD family secretion protein | - |
| A7A10_RS25350 (36863) | 36863..38959 | + | 2097 | WP_257115040.1 | peptidase domain-containing ABC transporter | - |
| A7A10_RS25355 (39129) | 39129..39440 | - | 312 | WP_001259758.1 | colicin V | - |
| A7A10_RS25360 (39418) | 39418..39654 | - | 237 | WP_032257624.1 | colicin V immunity protein | - |
| A7A10_RS25365 (40167) | 40167..40301 | - | 135 | WP_225381043.1 | colicin release lysis protein | - |
| A7A10_RS25370 (40346) | 40346..41462 | - | 1117 | Protein_31 | IS66 family transposase ISEc8 | Transposase |
| A7A10_RS25375 (41619) | 41619..41876 | - | 258 | Protein_32 | cloacin immunity family protein | - |
| A7A10_RS25380 (41886) | 41886..42041 | - | 156 | Protein_33 | colicin E3/pyocin S6 family cytotoxin | - |
| A7A10_RS25385 (42267) | 42267..42515 | - | 249 | WP_257115041.1 | hypothetical protein | - |
| A7A10_RS25390 (42607) | 42607..42882 | - | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| A7A10_RS25395 (42882) | 42882..43166 | - | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| A7A10_RS25400 (44079) | 44079..44936 | - | 858 | WP_000131011.1 | incFII family plasmid replication initiator RepA | - |
| A7A10_RS25405 (44929) | 44929..45003 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| A7A10_RS25410 (45052) | 45052..45177 | + | 126 | WP_001436741.1 | hypothetical protein | - |
| A7A10_RS25415 (45250) | 45250..45498 | - | 249 | WP_257185968.1 | replication regulatory protein RepA | - |
| A7A10_RS25420 (45782) | 45782..45931 | - | 150 | WP_001300273.1 | Hok/Gef family protein | Toxin Detail |
| - (45975) | 45975..46036 | + | 62 | NuclAT_1 | - | - |
| - (45975) | 45975..46036 | + | 62 | NuclAT_1 | - | - |
| - (45975) | 45975..46036 | + | 62 | NuclAT_1 | - | - |
| - (45975) | 45975..46036 | + | 62 | NuclAT_1 | - | - |
| A7A10_RS25425 (46211) | 46211..46345 | - | 135 | WP_001058542.1 | hypothetical protein | - |
| A7A10_RS25430 (46696) | 46696..47156 | - | 461 | Protein_43 | thermonuclease family protein | - |
| A7A10_RS25435 (47186) | 47186..48799 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| A7A10_RS25440 (48830) | 48830..49180 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| A7A10_RS25445 (49177) | 49177..49602 | - | 426 | WP_257115045.1 | IS66 family transposase ISEc23 | Transposase |
| A7A10_RS25450 (50442) | 50442..50645 | - | 204 | WP_001327131.1 | hypothetical protein | - |
| A7A10_RS25455 (50800) | 50800..51357 | - | 558 | WP_000139319.1 | fertility inhibition protein FinO | - |
| A7A10_RS25460 (51460) | 51460..52320 | - | 861 | WP_257115044.1 | alpha/beta hydrolase | - |
| A7A10_RS25465 (52379) | 52379..53119 | - | 741 | Protein_50 | conjugal transfer pilus acetylase TraX | - |
| A7A10_RS25470 (53139) | 53139..58409 | - | 5271 | WP_257185969.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| A7A10_RS25475 (58491) | 58491..58718 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| A7A10_RS25480 (58718) | 58718..59116 | + | 399 | WP_000911315.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| A7A10_RS25485 (59125) | 59125..61323 | - | 2199 | WP_257185970.1 | type IV conjugative transfer system coupling protein TraD | - |
| A7A10_RS25490 (61575) | 61575..62285 | - | 711 | WP_042032882.1 | conjugal transfer complement resistance protein TraT | - |
| A7A10_RS25495 (62331) | 62331..62852 | - | 522 | WP_000632670.1 | conjugal transfer entry exclusion protein TraS | - |
| A7A10_RS25500 (62885) | 62885..65701 | - | 2817 | WP_001007052.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| A7A10_RS25505 (65698) | 65698..67071 | - | 1374 | WP_170926168.1 | conjugal transfer pilus assembly protein TraH | - |
| A7A10_RS25510 (67071) | 67071..67451 | - | 381 | WP_042054351.1 | F-type conjugal transfer protein TrbF | - |
| A7A10_RS25515 (67438) | 67438..67779 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| A7A10_RS25520 (67709) | 67709..68254 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| A7A10_RS25525 (68241) | 68241..68525 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| A7A10_RS25530 (68606) | 68606..68842 | + | 237 | WP_001352846.1 | hypothetical protein | - |
| A7A10_RS25535 (68922) | 68922..69269 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| A7A10_RS25540 (69285) | 69285..70028 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| A7A10_RS25545 (70021) | 70021..70278 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| A7A10_RS25550 (70305) | 70305..72113 | - | 1809 | WP_257185972.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| A7A10_RS25555 (72110) | 72110..72748 | - | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| A7A10_RS25560 (72757) | 72757..73749 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| A7A10_RS25565 (73746) | 73746..74378 | - | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| A7A10_RS25570 (74375) | 74375..74761 | - | 387 | WP_000099691.1 | type-F conjugative transfer system protein TrbI | - |
| A7A10_RS25575 (74758) | 74758..77382 | - | 2625 | WP_257185973.1 | type IV secretion system protein TraC | - |
| A7A10_RS25580 (77542) | 77542..77763 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| A7A10_RS25585 (77898) | 77898..78413 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| A7A10_RS25590 (78410) | 78410..78661 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| A7A10_RS25595 (78673) | 78673..78870 | - | 198 | WP_024179215.1 | conjugal transfer protein TrbD | - |
| A7A10_RS25600 (78857) | 78857..79447 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| A7A10_RS25605 (79437) | 79437..80864 | - | 1428 | WP_000146684.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| A7A10_RS25610 (80864) | 80864..81592 | - | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| A7A10_RS25615 (81579) | 81579..82145 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| A7A10_RS25620 (82167) | 82167..82478 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| A7A10_RS25625 (82493) | 82493..82858 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| A7A10_RS25630 (82901) | 82901..83116 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| A7A10_RS25635 (83252) | 83252..83899 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| A7A10_RS25640 (84091) | 84091..84474 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| A7A10_RS25645 (84854) | 84854..85444 | + | 591 | WP_001375132.1 | hypothetical protein | VF |
| A7A10_RS25650 (85740) | 85740..86561 | - | 822 | WP_257185976.1 | DUF932 domain-containing protein | - |
| A7A10_RS25655 (86680) | 86680..86967 | - | 288 | WP_000107542.1 | hypothetical protein | - |
| A7A10_RS25660 (86992) | 86992..87198 | - | 207 | WP_000547965.1 | hypothetical protein | - |
| A7A10_RS25665 (87268) | 87268..87565 | + | 298 | Protein_90 | hypothetical protein | - |
| A7A10_RS25670 (87866) | 87866..87991 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| A7A10_RS25675 (87933) | 87933..88082 | - | 150 | Protein_92 | DUF5431 family protein | - |
| - (88089) | 88089..88287 | - | 199 | NuclAT_0 | - | - |
| - (88089) | 88089..88287 | - | 199 | NuclAT_0 | - | - |
| - (88089) | 88089..88287 | - | 199 | NuclAT_0 | - | - |
| - (88089) | 88089..88287 | - | 199 | NuclAT_0 | - | - |
| A7A10_RS25680 (88256) | 88256..89018 | - | 763 | Protein_93 | plasmid SOS inhibition protein A | - |
| A7A10_RS25685 (89015) | 89015..89449 | - | 435 | WP_257185946.1 | conjugation system SOS inhibitor PsiB | - |
| A7A10_RS25690 (89504) | 89504..91462 | - | 1959 | WP_257185947.1 | ParB/RepB/Spo0J family partition protein | - |
| A7A10_RS25695 (91528) | 91528..91761 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| A7A10_RS25700 (91824) | 91824..92363 | - | 540 | WP_000290838.1 | single-stranded DNA-binding protein | - |
| A7A10_RS25705 (92681) | 92681..93190 | + | 510 | WP_071532140.1 | hypothetical protein | - |
| A7A10_RS25710 (93160) | 93160..93351 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| A7A10_RS25715 (93348) | 93348..93770 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| A7A10_RS25720 (93817) | 93817..94242 | - | 426 | WP_257185952.1 | antirestriction protein | - |
| A7A10_RS25725 (94656) | 94656..95432 | - | 777 | WP_001005032.1 | hypothetical protein | - |
| A7A10_RS25730 (95478) | 95478..96032 | - | 555 | WP_001358893.1 | DUF1380 family protein | - |
| A7A10_RS25735 (95926) | 95926..96147 | - | 222 | WP_001104904.1 | hypothetical protein | - |
| A7A10_RS25740 (96148) | 96148..96831 | - | 684 | WP_000085939.1 | DNA methylase | - |
| A7A10_RS25745 (96908) | 96908..97213 | - | 306 | WP_257185953.1 | hypothetical protein | - |
| A7A10_RS25750 (97217) | 97217..98118 | - | 902 | Protein_107 | DUF1281 domain-containing protein | - |
| A7A10_RS25755 (98985) | 98985..99956 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| A7A10_RS25760 (99956) | 99956..101122 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| A7A10_RS25765 (101710) | 101710..102465 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| A7A10_RS25770 (103187) | 103187..103993 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| A7A10_RS25775 (103994) | 103994..104299 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| A7A10_RS25780 (104301) | 104301..104519 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| A7A10_RS25785 (105099) | 105099..106187 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| A7A10_RS25790 (106189) | 106189..107619 | + | 1431 | WP_251003572.1 | P-loop NTPase fold protein | - |
| A7A10_RS25795 (107695) | 107695..108075 | + | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| A7A10_RS25800 (108072) | 108072..108419 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| A7A10_RS25805 (108469) | 108469..109909 | + | 1441 | Protein_118 | IS66 family transposase ISEc8 | Transposase |
| A7A10_RS25810 (109950) | 109950..110295 | + | 346 | Protein_119 | Tn3 family transposase | - |
| A7A10_RS25815 (110362) | 110362..111192 | - | 831 | WP_257185954.1 | polysaccharide deacetylase family protein | - |
| A7A10_RS25820 (112653) | 112653..113990 | + | 1338 | WP_257115016.1 | MFS transporter | - |
| A7A10_RS25825 (114001) | 114001..114336 | - | 336 | WP_257115017.1 | SMR family transporter | - |
| A7A10_RS25830 (114662) | 114662..115573 | - | 912 | WP_257185955.1 | VirK/YbjX family protein | - |
| A7A10_RS25835 (116488) | 116488..117609 | + | 1122 | WP_257115020.1 | D-inositol-3-phosphate glycosyltransferase | VF |
| A7A10_RS25840 (117835) | 117835..118078 | - | 244 | Protein_125 | integrase core domain-containing protein | - |
| A7A10_RS25845 (118113) | 118113..120187 | - | 2075 | Protein_126 | Tn3 family transposase | - |
| A7A10_RS25850 (120232) | 120232..120360 | + | 129 | WP_257115021.1 | IS3 family transposase ISEc24 | Transposase |
| A7A10_RS25855 (120545) | 120545..121696 | + | 1152 | WP_257185956.1 | IS30 family transposase IS30D | Transposase |
| A7A10_RS25860 (121808) | 121808..121914 | + | 107 | Protein_129 | ATP-binding protein | - |
| A7A10_RS25865 (122331) | 122331..123232 | - | 902 | Protein_130 | DUF4158 domain-containing protein | - |
| A7A10_RS25870 (123882) | 123882..124376 | - | 495 | Protein_131 | IS21 family transposase | - |
| A7A10_RS25875 (125083) | 125083..125490 | + | 408 | WP_257115029.1 | hypothetical protein | - |
| A7A10_RS25880 (125496) | 125496..126086 | + | 591 | WP_257185957.1 | hypothetical protein | - |
| A7A10_RS25885 (126238) | 126238..126771 | + | 534 | WP_257115027.1 | hypothetical protein | VF |
| A7A10_RS25890 (126831) | 126831..127508 | + | 678 | WP_257185958.1 | hypothetical protein | VF |
| A7A10_RS25895 (127462) | 127462..130041 | + | 2580 | WP_257115025.1 | hypothetical protein | VF |
| A7A10_RS25900 (130647) | 130647..131621 | + | 975 | WP_257115024.1 | fimbrial protein | - |
| A7A10_RS25905 (131902) | 131902..134538 | + | 2637 | Protein_138 | Tn3 family transposase TnpA_Tn3 | Transposase |
| A7A10_RS25910 (135059) | 135059..135316 | + | 258 | WP_257115022.1 | biofilm development regulator YmgB/AriR family protein | - |
| A7A10_RS25915 (135395) | 135395..135661 | - | 267 | Protein_140 | IS1 family transposase | - |
| A7A10_RS25920 (135842) | 135842..136738 | - | 897 | Protein_141 | IS3 family transposase ISSd1 | Transposase |
| A7A10_RS25925 (136745) | 136745..137896 | - | 1152 | WP_257185956.1 | IS30 family transposase IS30D | Transposase |
| A7A10_RS25930 (137961) | 137961..138140 | - | 180 | Protein_143 | IS3 family transposase | - |
| A7A10_RS25935 (138263) | 138263..138514 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| A7A10_RS25940 (138511) | 138511..138798 | + | 288 | WP_001270417.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| A7A10_RS25945 (138800) | 138800..139211 | + | 412 | Protein_146 | DDE-type integrase/transposase/recombinase | - |
| A7A10_RS25950 (139856) | 139856..140833 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| A7A10_RS25955 (141118) | 141118..141858 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| A7A10_RS25960 (141979) | 141979..142167 | - | 189 | WP_172944323.1 | serine/threonine protein kinase | - |
| A7A10_RS25965 (142542) | 142542..143444 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| A7A10_RS25970 (143513) | 143513..144622 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| A7A10_RS25975 (145055) | 145055..146008 | - | 954 | WP_000280980.1 | hypothetical protein | VF |
| A7A10_RS25980 (147261) | 147261..147661 | - | 401 | Protein_153 | integrase core domain-containing protein | - |
| A7A10_RS25985 (147735) | 147735..147992 | + | 258 | Protein_154 | IS3 family transposase IS911 | Transposase |
| A7A10_RS25990 (148060) | 148060..149211 | + | 1152 | WP_257185956.1 | IS30 family transposase IS30D | Transposase |
| A7A10_RS25995 (149221) | 149221..150123 | + | 903 | Protein_156 | IS3 family transposase ISLad1 | Transposase |
| A7A10_RS26000 (150132) | 150132..150718 | + | 587 | Protein_157 | IS3 family transposase IS1351 | Transposase |
| A7A10_RS26005 (151096) | 151096..152385 | + | 1290 | WP_187225008.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|