MGE detailed information

MGE type: Conjugative plasmid        MGE length: 71222 bp
Accession: NZ_CP053082        Location: 1..71222         Organism: Escherichia coli strain HB37       Replicon: plasmid pHB37-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKW69_RS26090 () 109..357 + 249 WP_000083837.1 replication regulatory protein RepA -
HKW69_RS26095 () 602..676 + 75 WP_001375168.1 RepA leader peptide Tap -
HKW69_RS26100 () 669..1526 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
HKW69_RS26105 () 2227..2367 + 141 WP_001333237.1 hypothetical protein -
HKW69_RS26110 () 2465..3107 + 643 Protein_4 CPBP family intramembrane metalloprotease -
HKW69_RS26115 () 3200..3457 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
HKW69_RS26120 () 3390..3791 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
HKW69_RS26125 () 4040..4455 + 416 Protein_7 IS1 family transposase IS1R Transposase
HKW69_RS26130 () 4491..5036 - 546 Protein_8 Tn3 family transposase TnpA_Tn3 Transposase
HKW69_RS26135 () 5102..5806 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HKW69_RS26140 () 6262..7461 - 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
HKW69_RS26145 () 7471..7659 - 189 WP_000957857.1 hypothetical protein -
HKW69_RS26150 () 7751..8287 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
HKW69_RS26155 () 8470..9330 + 861 WP_000027057.1 Beta-lactamase TEM ARG
HKW69_RS26160 () 9500..10255 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
HKW69_RS26165 () 10336..10617 - 282 WP_015059004.1 sodium/hydrogen exchanger -
HKW69_RS26170 () 10705..11409 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
HKW69_RS26175 () 11475..11540 + 66 Protein_17 IS1 family transposase -
HKW69_RS26180 () 12989..13223 + 235 Protein_18 type II toxin-antitoxin system RelE/ParE family toxin -
HKW69_RS26185 () 13351..13632 + 282 WP_001333089.1 hypothetical protein -
HKW69_RS26190 () 13769..14104 - 336 WP_099723228.1 plasmid partitioning/stability family protein -
HKW69_RS26195 () 14107..15069 - 963 WP_000959884.1 plasmid segregation protein ParM -
HKW69_RS26200 () 15216..15509 + 294 WP_032146011.1 hypothetical protein -
HKW69_RS26205 () 15586..16269 + 684 WP_000085883.1 DNA methylase -
HKW69_RS26210 () 16270..16491 + 222 WP_001104881.1 hypothetical protein -
HKW69_RS26215 () 16505..16939 + 435 WP_000274503.1 DUF1380 family protein -
HKW69_RS26220 () 16990..17766 + 777 WP_001383963.1 hypothetical protein -
HKW69_RS26230 () 18307..18609 + 303 WP_001671341.1 antirestriction protein -
HKW69_RS26235 () 18656..19078 + 423 WP_000271762.1 DUF1380 family protein -
HKW69_RS26240 () 19075..19266 + 192 WP_001027493.1 hypothetical protein -
HKW69_RS26245 () 19580..21247 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
HKW69_RS26250 () 22647..22877 + 231 WP_000218642.1 hypothetical protein -
HKW69_RS26255 () 22929..24290 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
HKW69_RS26260 () 24336..24899 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
HKW69_RS26265 () 24985..25446 - 462 WP_001479900.1 hypothetical protein -
HKW69_RS26270 () 25748..26275 + 528 WP_000290834.1 single-stranded DNA-binding protein -
HKW69_RS26275 () 26333..26566 + 234 WP_000006003.1 DUF905 family protein -
HKW69_RS26280 () 26627..28650 + 2024 Protein_37 ParB/RepB/Spo0J family partition protein -
HKW69_RS26285 () 28719..29153 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
HKW69_RS26290 () 29150..29869 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- () 29881..30105 + 225 NuclAT_0 - -
- () 29881..30105 + 225 NuclAT_0 - -
- () 29881..30105 + 225 NuclAT_0 - -
- () 29881..30105 + 225 NuclAT_0 - -
HKW69_RS26295 () 29890..30069 - 180 WP_001309233.1 hypothetical protein -
- () 30038..30103 + 66 - - Antitoxin Detail
HKW69_RS26300 () 30149..30307 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
HKW69_RS26960 () 30545..30922 - 378 Protein_42 hypothetical protein -
HKW69_RS26310 () 31222..31518 + 297 WP_001272251.1 hypothetical protein -
HKW69_RS26315 () 31629..32450 + 822 WP_001234445.1 DUF945 domain-containing protein -
HKW69_RS26320 () 32747..33394 - 648 WP_015059008.1 hypothetical protein VF
HKW69_RS26325 () 33671..34054 + 384 WP_000124981.1 relaxosome protein TraM -
HKW69_RS26330 () 34245..34931 + 687 WP_015059009.1 PAS domain-containing protein -
HKW69_RS26335 () 35025..35252 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
HKW69_RS26340 () 35286..35651 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
HKW69_RS26345 () 35666..35977 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
HKW69_RS26350 () 35999..36565 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
HKW69_RS26355 () 36576..37280 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
HKW69_RS26360 () 37280..38707 + 1428 WP_032297072.1 conjugal transfer protein TraB -
HKW69_RS26365 () 38697..39287 + 591 WP_000002778.1 conjugal transfer protein TraP -
HKW69_RS26370 () 39241..39471 + 231 WP_001352845.1 conjugal transfer protein TrbD -
HKW69_RS26375 () 39483..39734 + 252 WP_001038341.1 conjugal transfer protein TrbG -
HKW69_RS26380 () 39731..40246 + 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
HKW69_RS26385 () 40381..40602 + 222 WP_001278692.1 conjugal transfer protein TraR -
HKW69_RS26390 () 40762..43389 + 2628 WP_015059012.1 type IV secretion system protein TraC -
HKW69_RS26395 () 43386..43772 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
HKW69_RS26400 () 43769..44401 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
HKW69_RS26405 () 44398..45390 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
HKW69_RS26410 () 45417..45725 + 309 WP_000412447.1 hypothetical protein -
HKW69_RS26415 () 45788..46309 + 522 WP_015059014.1 hypothetical protein -
HKW69_RS26420 () 46336..46974 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
HKW69_RS26425 () 46971..47342 + 372 WP_000056336.1 hypothetical protein -
HKW69_RS26430 () 47368..47790 + 423 WP_001229309.1 HNH endonuclease -
HKW69_RS26435 () 47787..48923 + 1137 Protein_68 conjugal transfer protein TraN -
HKW69_RS26440 () 49011..50239 + 1229 WP_166738926.1 IS3 family transposase IS2 Transposase
HKW69_RS26445 () 50260..50973 + 714 Protein_70 conjugal transfer protein TraN -
HKW69_RS26450 () 51000..51257 + 258 WP_053913405.1 conjugal transfer protein TrbE -
HKW69_RS26455 () 51250..51993 + 744 WP_015059017.1 type-F conjugative transfer system pilin assembly protein TraF -
HKW69_RS26460 () 52109..52390 + 282 WP_000549793.1 type-F conjugative transfer system pilin chaperone TraQ -
HKW69_RS26465 () 52377..52925 + 549 Protein_74 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HKW69_RS26470 () 52915..53229 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
HKW69_RS26475 () 53563..54937 + 1375 Protein_76 conjugal transfer protein TraH -
HKW69_RS26480 () 54934..57750 + 2817 WP_015059018.1 conjugal transfer mating pair stabilization protein TraG -
HKW69_RS26485 () 57783..58304 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
HKW69_RS26490 () 58329..59060 + 732 WP_000850422.1 complement resistance protein TraT -
HKW69_RS26495 () 59263..60000 + 738 WP_015059020.1 hypothetical protein -
HKW69_RS26500 () 60051..62231 + 2181 WP_021518883.1 type IV conjugative transfer system coupling protein TraD -
HKW69_RS26505 () 62231..67501 + 5271 WP_015059021.1 Multifunctional conjugation protein TraI Relaxase
HKW69_RS26510 () 67521..68267 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
HKW69_RS26515 () 68322..68882 + 561 WP_000139328.1 fertility inhibition protein FinO -
HKW69_RS26520 () 69014..69214 + 201 WP_015059022.1 hypothetical protein -
HKW69_RS26525 () 69600..70199 + 600 WP_032083981.1 hypothetical protein -
HKW69_RS26530 () 70363..70593 + 231 WP_001736714.1 hypothetical protein -
- () 70794..70853 - 60 NuclAT_1 - -
- () 70794..70853 - 60 NuclAT_1 - -
- () 70794..70853 - 60 NuclAT_1 - -
- () 70794..70853 - 60 NuclAT_1 - -
HKW69_RS26535 () 70898..71047 + 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance