MGE detailed information
MGE type: Conjugative plasmid MGE length: 83548 bp
Accession: NZ_CP045943 Location: 1..83548 Organism: Shigella flexneri 2a strain AUSMDU00010535 Replicon: plasmid pAUSMDU00010535_02
Accession: NZ_CP045943 Location: 1..83548 Organism: Shigella flexneri 2a strain AUSMDU00010535 Replicon: plasmid pAUSMDU00010535_02
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GJE14_RS25045 (1) | 1..858 | + | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| GJE14_RS25050 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| GJE14_RS25055 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| GJE14_RS25060 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| GJE14_RS25065 (3383) | 3383..4080 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| GJE14_RS25070 (4159) | 4159..4856 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| GJE14_RS25075 (4983) | 4983..5360 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| GJE14_RS25080 (5427) | 5427..8393 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| GJE14_RS25085 (8396) | 8396..8836 | - | 441 | Protein_8 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| GJE14_RS25090 (8888) | 8888..9592 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GJE14_RS25095 (9762) | 9762..10043 | - | 282 | Protein_10 | transposase zinc-binding domain-containing protein | - |
| GJE14_RS25100 (10190) | 10190..11050 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| GJE14_RS25105 (11349) | 11349..12053 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GJE14_RS25110 (12252) | 12252..12602 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| GJE14_RS25115 (12805) | 12805..13818 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| GJE14_RS25120 (13976) | 13976..14449 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| GJE14_RS25125 (14580) | 14580..15368 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| GJE14_RS25130 (15574) | 15574..15921 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| GJE14_RS25135 (15915) | 15915..16754 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| GJE14_RS25140 (16882) | 16882..17085 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| GJE14_RS25145 (17241) | 17241..18446 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| GJE14_RS25150 (18457) | 18457..18762 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| GJE14_RS25925 (18806) | 18806..18871 | + | 66 | Protein_22 | EAL domain-containing protein | - |
| GJE14_RS25155 (18989) | 18989..19753 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| GJE14_RS25160 (20246) | 20246..20830 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| GJE14_RS25165 (20830) | 20830..22068 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| GJE14_RS25170 (22065) | 22065..22970 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| GJE14_RS25175 (23092) | 23092..23796 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GJE14_RS25180 (23931) | 23931..24026 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| GJE14_RS25185 (24152) | 24152..24889 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| GJE14_RS25195 (25652) | 25652..26349 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| GJE14_RS25200 (26386) | 26386..26620 | + | 235 | Protein_31 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GJE14_RS25205 (26748) | 26748..27029 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| GJE14_RS25210 (27152) | 27152..27502 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| GJE14_RS25215 (27505) | 27505..28467 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| GJE14_RS25220 (28614) | 28614..28907 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| GJE14_RS25225 (28984) | 28984..29667 | + | 684 | WP_000085883.1 | DNA methylase | - |
| GJE14_RS25230 (29668) | 29668..29889 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| GJE14_RS25235 (29903) | 29903..30337 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| GJE14_RS25935 (30388) | 30388..31164 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| GJE14_RS25250 (31582) | 31582..32007 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| GJE14_RS25255 (32054) | 32054..32476 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| GJE14_RS25260 (32473) | 32473..32664 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| GJE14_RS25265 (33702) | 33702..33932 | + | 231 | WP_000218647.1 | hypothetical protein | - |
| GJE14_RS25270 (33984) | 33984..35345 | + | 1362 | WP_000170671.1 | DUF3560 domain-containing protein | - |
| GJE14_RS25275 (35392) | 35392..35955 | + | 564 | WP_016240496.1 | class I SAM-dependent methyltransferase | - |
| GJE14_RS26525 (36041) | 36041..36484 | - | 444 | Protein_46 | hypothetical protein | - |
| GJE14_RS25285 (36786) | 36786..37307 | + | 522 | WP_033807850.1 | single-stranded DNA-binding protein | - |
| GJE14_RS25290 (37363) | 37363..37596 | + | 234 | WP_000005971.1 | DUF905 domain-containing protein | - |
| GJE14_RS25295 (37660) | 37660..39618 | + | 1959 | WP_112324844.1 | ParB/RepB/Spo0J family partition protein | - |
| GJE14_RS25300 (39673) | 39673..40107 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| GJE14_RS25305 (40104) | 40104..40866 | + | 763 | Protein_51 | plasmid SOS inhibition protein A | - |
| GJE14_RS25310 (40844) | 40844..41023 | - | 180 | WP_001334662.1 | hypothetical protein | - |
| - (40835) | 40835..41059 | + | 225 | NuclAT_0 | - | - |
| - (40835) | 40835..41059 | + | 225 | NuclAT_0 | - | - |
| - (40835) | 40835..41059 | + | 225 | NuclAT_0 | - | - |
| - (40835) | 40835..41059 | + | 225 | NuclAT_0 | - | - |
| GJE14_RS26530 (41045) | 41045..41194 | + | 150 | Protein_53 | plasmid maintenance protein Mok | - |
| GJE14_RS25315 (41136) | 41136..41261 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| GJE14_RS25320 (41580) | 41580..41876 | - | 297 | Protein_55 | hypothetical protein | - |
| GJE14_RS25330 (42176) | 42176..42472 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| GJE14_RS25335 (42583) | 42583..43404 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| GJE14_RS25340 (43701) | 43701..44291 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| GJE14_RS25345 (44624) | 44624..45007 | + | 384 | WP_001151529.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| GJE14_RS25350 (45199) | 45199..45846 | + | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| GJE14_RS25355 (45966) | 45966..46193 | + | 228 | WP_000589556.1 | conjugal transfer relaxosome protein TraY | - |
| GJE14_RS25360 (46227) | 46227..46586 | + | 360 | WP_001098994.1 | type IV conjugative transfer system pilin TraA | - |
| GJE14_RS25365 (46601) | 46601..46912 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| GJE14_RS25370 (46934) | 46934..47500 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| GJE14_RS25375 (47487) | 47487..48215 | + | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| GJE14_RS25380 (48215) | 48215..49642 | + | 1428 | WP_033807957.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| GJE14_RS25385 (49632) | 49632..50222 | + | 591 | WP_000002784.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| GJE14_RS25390 (50209) | 50209..50529 | + | 321 | WP_012881128.1 | conjugal transfer protein TrbD | - |
| GJE14_RS25395 (50526) | 50526..51041 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GJE14_RS25400 (51176) | 51176..51397 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| GJE14_RS25405 (51390) | 51390..51803 | + | 414 | WP_000549589.1 | hypothetical protein | - |
| GJE14_RS25410 (51796) | 51796..52269 | + | 474 | WP_033807958.1 | hypothetical protein | - |
| GJE14_RS25415 (52368) | 52368..52586 | + | 219 | WP_033807959.1 | hypothetical protein | - |
| GJE14_RS25420 (52614) | 52614..52961 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| GJE14_RS25425 (53087) | 53087..55717 | + | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| GJE14_RS25430 (55714) | 55714..56100 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| GJE14_RS25435 (56097) | 56097..56729 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| GJE14_RS25440 (56726) | 56726..57718 | + | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| GJE14_RS25445 (57748) | 57748..58053 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| GJE14_RS25450 (58062) | 58062..58700 | + | 639 | WP_033807960.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GJE14_RS25455 (58697) | 58697..59077 | + | 381 | WP_001462111.1 | hypothetical protein | - |
| GJE14_RS25460 (59313) | 59313..61217 | + | 1905 | WP_225620370.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GJE14_RS25465 (61244) | 61244..61501 | + | 258 | WP_033807961.1 | conjugal transfer protein TrbE | - |
| GJE14_RS25470 (61494) | 61494..62237 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GJE14_RS25475 (62251) | 62251..62592 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| GJE14_RS25480 (62573) | 62573..62908 | - | 336 | WP_001620807.1 | hypothetical protein | - |
| GJE14_RS25485 (62989) | 62989..63273 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GJE14_RS25490 (63260) | 63260..63805 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GJE14_RS25495 (63735) | 63735..64082 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| GJE14_RS25500 (64063) | 64063..64455 | + | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| GJE14_RS25505 (64442) | 64442..65815 | + | 1374 | WP_033807962.1 | conjugal transfer pilus assembly protein TraH | - |
| GJE14_RS25510 (65812) | 65812..68637 | + | 2826 | WP_033807963.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| GJE14_RS25515 (68634) | 68634..69143 | + | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| GJE14_RS25520 (69157) | 69157..69888 | + | 732 | WP_012881123.1 | conjugal transfer complement resistance protein TraT | - |
| GJE14_RS25525 (70091) | 70091..70828 | + | 738 | WP_012881122.1 | hypothetical protein | - |
| GJE14_RS25530 (70879) | 70879..73095 | + | 2217 | WP_033807964.1 | type IV conjugative transfer system coupling protein TraD | - |
| GJE14_RS25535 (73095) | 73095..78365 | + | 5271 | WP_033807965.1 | Multifunctional conjugation protein TraI | Relaxase |
| GJE14_RS25540 (78385) | 78385..79131 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| GJE14_RS25545 (79186) | 79186..79746 | + | 561 | WP_033807966.1 | fertility inhibition protein FinO | - |
| GJE14_RS25550 (79878) | 79878..80090 | + | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| GJE14_RS25555 (80336) | 80336..80797 | + | 462 | WP_001233850.1 | thermonuclease family protein | - |
| GJE14_RS25560 (80843) | 80843..81052 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| GJE14_RS25565 (81090) | 81090..81680 | + | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| GJE14_RS25570 (81835) | 81835..82308 | + | 474 | WP_016240489.1 | hypothetical protein | - |
| - (82451) | 82451..82510 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (82451) | 82451..82510 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (82451) | 82451..82510 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (82451) | 82451..82510 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| GJE14_RS25575 (82555) | 82555..82704 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| GJE14_RS25580 (82989) | 82989..83237 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| GJE14_RS26535 (83352) | 83352..83536 | + | 185 | Protein_107 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|