MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 127353 bp
Accession: NZ_CP045692 Location: 1..127353 Organism: Klebsiella pneumoniae strain TK421 Replicon: plasmid pTK421_2
Accession: NZ_CP045692 Location: 1..127353 Organism: Klebsiella pneumoniae strain TK421 Replicon: plasmid pTK421_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GHA50_RS00770 () | 1..1011 | + | 1011 | WP_004211839.1 | RepB family plasmid replication initiator protein | - |
| GHA50_RS00775 () | 1757..2496 | - | 740 | Protein_1 | tyrosine-type recombinase/integrase | - |
| GHA50_RS00780 () | 2844..3117 | + | 274 | Protein_2 | IS3 family transposase | - |
| GHA50_RS00785 () | 3255..3791 | - | 537 | WP_153459061.1 | plasmid transfer protein | - |
| GHA50_RS00790 () | 4002..4984 | - | 983 | Protein_4 | IS3 family transposase | - |
| GHA50_RS00795 () | 5051..6067 | + | 1017 | WP_153459062.1 | IS110 family transposase ISKpn2 | Transposase |
| GHA50_RS00800 () | 6291..6407 | - | 117 | Protein_6 | IS3 family transposase ISYpe1 | Transposase |
| GHA50_RS00805 () | 6557..6825 | - | 269 | Protein_7 | IS3 family transposase ISEc14 | Transposase |
| GHA50_RS00810 () | 6849..7817 | - | 969 | WP_153459063.1 | IS110 family transposase ISSm3 | Transposase |
| GHA50_RS00815 () | 7995..8111 | - | 117 | Protein_9 | transposase | - |
| GHA50_RS00820 () | 8144..8749 | + | 606 | WP_194285406.1 | hypothetical protein | - |
| GHA50_RS00825 () | 8736..8978 | + | 243 | WP_032720855.1 | hypothetical protein | - |
| GHA50_RS00830 () | 9026..9493 | + | 468 | WP_153459064.1 | hypothetical protein | - |
| GHA50_RS00835 () | 9503..9910 | + | 408 | WP_032720853.1 | hypothetical protein | - |
| GHA50_RS00840 () | 9953..10912 | + | 960 | WP_153459065.1 | DNA replication protein | - |
| GHA50_RS00845 () | 10909..11667 | + | 759 | WP_153459066.1 | hypothetical protein | - |
| GHA50_RS00850 () | 12201..12518 | + | 318 | WP_012540152.1 | hypothetical protein | - |
| GHA50_RS00855 () | 12584..13720 | - | 1137 | WP_004150541.1 | tyrosine-type recombinase/integrase | - |
| GHA50_RS00860 () | 13898..14152 | + | 255 | WP_025862222.1 | hypothetical protein | - |
| GHA50_RS00865 () | 14239..15266 | + | 1028 | Protein_19 | hypothetical protein | - |
| GHA50_RS00870 () | 15306..16426 | + | 1121 | WP_153459067.1 | IS3 family transposase ISKpn34 | Transposase |
| GHA50_RS00875 () | 16539..17063 | + | 525 | Protein_21 | IS481 family transposase ISErsp1 | Transposase |
| GHA50_RS00880 () | 17123..17446 | - | 324 | WP_153459068.1 | hypothetical protein | - |
| GHA50_RS00885 () | 17475..17681 | - | 207 | Protein_23 | molybdopterin-dependent oxidoreductase | - |
| GHA50_RS00890 () | 17635..18144 | - | 510 | WP_025862333.1 | cytochrome b/b6 domain-containing protein | - |
| GHA50_RS00895 () | 18367..19064 | + | 698 | WP_171893191.1 | IS1 family transposase IS1X2 | Transposase |
| GHA50_RS00900 () | 19133..20074 | + | 942 | WP_153459069.1 | Recombination-promoting nuclease RpnA | VF |
| GHA50_RS00905 () | 20071..20367 | - | 297 | Protein_27 | hypothetical protein | - |
| GHA50_RS00910 () | 20754..21059 | - | 306 | Protein_28 | Tn3 family transposase ISEc63 | Transposase |
| GHA50_RS00915 () | 21251..21640 | + | 390 | WP_142988532.1 | IS66 family transposase ISEc8 | Transposase |
| GHA50_RS00920 () | 21724..22419 | + | 696 | Protein_30 | IS1 family transposase IS1S | Transposase |
| GHA50_RS00925 () | 22431..26315 | - | 3885 | Protein_31 | Multifunctional conjugation protein TraI | Relaxase |
| GHA50_RS00930 () | 26317..28305 | - | 1989 | WP_153459070.1 | type IV conjugative transfer system coupling protein TraD | - |
| GHA50_RS00935 () | 28605..28928 | - | 324 | WP_032440442.1 | hypothetical protein | - |
| GHA50_RS00940 () | 29177..30487 | - | 1311 | WP_153459071.1 | hypothetical protein | - |
| GHA50_RS00945 () | 30495..32048 | - | 1554 | WP_153459072.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| GHA50_RS00950 () | 32051..33415 | - | 1365 | WP_115195638.1 | conjugal transfer protein TraH | - |
| GHA50_RS00955 () | 33412..33965 | - | 554 | Protein_37 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GHA50_RS00960 () | 34010..34717 | - | 708 | Protein_38 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GHA50_RS00965 () | 34810..36038 | + | 1229 | WP_194285404.1 | IS3 family transposase IS2 | Transposase |
| GHA50_RS00970 () | 36971..37837 | - | 867 | WP_153459074.1 | replication initiation protein | - |
| GHA50_RS00975 () | 38610..39020 | - | 411 | Protein_41 | IS91 family transposase ISShvi3 | Transposase |
| GHA50_RS00980 () | 39102..39623 | - | 522 | WP_153459100.1 | hypothetical protein | - |
| GHA50_RS00985 () | 39681..40073 | - | 393 | WP_194285405.1 | hypothetical protein | - |
| GHA50_RS00990 () | 40110..41054 | - | 945 | WP_114499703.1 | hypothetical protein | - |
| GHA50_RS26745 () | 41215..41460 | - | 246 | Protein_45 | hypothetical protein | - |
| GHA50_RS00995 () | 41847..42221 | + | 375 | WP_153459075.1 | TIR domain-containing protein | - |
| GHA50_RS01000 () | 42231..43184 | + | 954 | WP_153459076.1 | caspase family protein | - |
| GHA50_RS01005 () | 43427..43918 | + | 492 | WP_153459077.1 | toll/interleukin-1 receptor domain-containing protein | - |
| GHA50_RS01010 () | 44378..44959 | + | 582 | WP_153459078.1 | hypothetical protein | - |
| GHA50_RS01015 () | 45113..46114 | + | 1002 | WP_153459079.1 | Abi family protein | - |
| GHA50_RS01020 () | 46322..46762 | - | 441 | WP_153459080.1 | hypothetical protein | - |
| GHA50_RS01025 () | 46781..47374 | - | 594 | WP_153459081.1 | hypothetical protein | - |
| GHA50_RS01030 () | 47605..47928 | + | 324 | WP_134864049.1 | hypothetical protein | - |
| GHA50_RS01035 () | 47918..48211 | - | 294 | WP_153459082.1 | korC | - |
| GHA50_RS01040 () | 48227..49360 | - | 1134 | WP_153459083.1 | DUF3800 domain-containing protein | - |
| GHA50_RS01045 () | 49446..50210 | - | 765 | WP_153459084.1 | hypothetical protein | - |
| GHA50_RS01050 () | 50223..50723 | - | 501 | WP_153459085.1 | hypothetical protein | - |
| GHA50_RS01055 () | 51199..52218 | + | 1020 | WP_153459007.1 | IS110 family transposase ISEc11 | Transposase |
| GHA50_RS01060 () | 52497..52766 | + | 270 | WP_153459086.1 | hypothetical protein | - |
| GHA50_RS01065 () | 52754..53329 | + | 576 | WP_153459087.1 | hypothetical protein | - |
| GHA50_RS01070 () | 53360..53833 | + | 474 | Protein_61 | DNA-binding protein | - |
| GHA50_RS01075 () | 54036..54650 | - | 615 | WP_080528809.1 | hypothetical protein | - |
| GHA50_RS01080 () | 54958..56003 | + | 1046 | Protein_63 | ISNCY family transposase ISLad2 | Transposase |
| GHA50_RS01085 () | 56662..57684 | - | 1023 | WP_153459088.1 | porphobilinogen synthase | - |
| GHA50_RS01090 () | 57833..58615 | - | 783 | Protein_65 | M14 family metallocarboxypeptidase | - |
| GHA50_RS01095 () | 58608..60137 | - | 1530 | Protein_66 | threonine--tRNA ligase | - |
| GHA50_RS01100 () | 60364..61308 | - | 945 | WP_044246536.1 | GTP cyclohydrolase I FolE2 | - |
| GHA50_RS01105 () | 61371..61793 | - | 423 | WP_004150723.1 | RNA polymerase-binding protein DksA | - |
| GHA50_RS01110 () | 61864..63063 | - | 1200 | WP_115223778.1 | GTP-binding protein | - |
| GHA50_RS01115 () | 63161..63613 | + | 453 | WP_153459089.1 | transcriptional repressor | - |
| GHA50_RS01120 () | 63762..64031 | + | 270 | Protein_71 | IS3 family transposase IS2 | Transposase |
| GHA50_RS01125 () | 64382..64699 | + | 318 | WP_153459090.1 | c-type lysozyme inhibitor | - |
| GHA50_RS01130 () | 65050..65220 | - | 171 | Protein_73 | iron dicitrate transport regulator FecR | - |
| GHA50_RS01135 () | 65249..65758 | - | 510 | WP_153459091.1 | peptide deformylase | - |
| GHA50_RS01140 () | 65996..66193 | - | 198 | Protein_75 | IS630 family transposase IS630 | Transposase |
| GHA50_RS01145 () | 66126..66770 | - | 645 | WP_153459092.1 | hypothetical protein | - |
| GHA50_RS01150 () | 66782..67213 | - | 432 | WP_115195597.1 | hypothetical protein | - |
| GHA50_RS01155 () | 67219..67575 | - | 357 | WP_032105368.1 | hypothetical protein | - |
| GHA50_RS01160 () | 68624..69823 | - | 1200 | WP_108523659.1 | MFS transporter | - |
| GHA50_RS01165 () | 69980..71704 | + | 1725 | WP_153459093.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| GHA50_RS01170 () | 71705..72652 | + | 948 | WP_016528828.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| GHA50_RS01175 () | 72652..74385 | + | 1734 | WP_040174938.1 | Aerobactin synthase | VF |
| GHA50_RS01180 () | 74389..75723 | + | 1335 | WP_016528830.1 | L-lysine N6-monooxygenase | VF |
| GHA50_RS01185 () | 75749..77950 | + | 2202 | WP_032105370.1 | Ferric aerobactin receptor | VF |
| GHA50_RS01190 () | 78616..78876 | + | 261 | WP_004145307.1 | DUF1471 domain-containing protein | - |
| GHA50_RS01195 () | 78919..79479 | + | 561 | WP_016529247.1 | TetR/AcrR family transcriptional regulator | - |
| GHA50_RS01200 () | 79516..79944 | + | 429 | WP_004902152.1 | DUF417 family protein | - |
| GHA50_RS01205 () | 80032..80307 | + | 276 | WP_115195602.1 | carboxymuconolactone decarboxylase family protein | - |
| GHA50_RS01210 () | 80370..80861 | + | 492 | WP_011251327.1 | DM13 domain-containing protein | - |
| GHA50_RS01215 () | 80910..81827 | + | 918 | WP_115195601.1 | DUF1471 domain-containing protein | - |
| GHA50_RS01220 () | 81918..82347 | + | 430 | Protein_91 | GAF domain-containing protein | - |
| GHA50_RS01225 () | 82376..83071 | + | 696 | Protein_92 | IS1 family transposase IS1S | Transposase |
| GHA50_RS26750 () | 83297..83419 | + | 123 | Protein_93 | DUF4158 domain-containing protein | - |
| GHA50_RS01230 () | 83429..83623 | + | 195 | Protein_94 | Tn3 family transposase | - |
| GHA50_RS01235 () | 83650..84738 | + | 1089 | Protein_95 | ISNCY family transposase ISKpn21 | Transposase |
| GHA50_RS01240 () | 84769..85356 | - | 588 | Protein_96 | hypothetical protein | - |
| GHA50_RS01245 () | 85357..86190 | - | 834 | Protein_97 | nucleotidyltransferase | - |
| GHA50_RS01250 () | 86557..86723 | + | 167 | Protein_98 | IS3 family transposase | - |
| GHA50_RS01255 () | 86837..87979 | + | 1143 | WP_016529303.1 | Histidine decarboxylase | VF |
| GHA50_RS01260 () | 88076..88303 | - | 228 | Protein_100 | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsE | VF |
| GHA50_RS01265 () | 90068..90238 | - | 171 | WP_142743642.1 | small membrane protein | - |
| GHA50_RS01270 () | 90283..90656 | - | 374 | Protein_102 | response regulator | - |
| GHA50_RS01275 () | 91639..92502 | - | 864 | WP_115195626.1 | incFII family plasmid replication initiator RepA | - |
| GHA50_RS01280 () | 92495..92572 | - | 78 | WP_115195650.1 | RepA leader peptide Tap | - |
| GHA50_RS01285 () | 92702..93822 | + | 1121 | WP_153459067.1 | IS3 family transposase ISKpn34 | Transposase |
| GHA50_RS01290 () | 93852..94679 | - | 828 | Protein_106 | IS5 family transposase ISKpn26 | Transposase |
| GHA50_RS01295 () | 95139..95836 | + | 698 | Protein_107 | IS1 family transposase IS1X4 | Transposase |
| GHA50_RS01300 () | 95836..96300 | - | 465 | Protein_108 | hypothetical protein | - |
| GHA50_RS01305 () | 96369..96665 | - | 297 | WP_094313394.1 | hydrogenase expression/formation protein HypD | - |
| GHA50_RS01310 () | 96899..97296 | + | 398 | Protein_110 | phosphonate ABC transporter substrate-binding protein | - |
| GHA50_RS01320 () | 97784..97942 | - | 159 | WP_115195635.1 | type I toxin-antitoxin system Hok family toxin | - |
| GHA50_RS01325 () | 98617..98925 | + | 309 | WP_052463135.1 | hypothetical protein | - |
| GHA50_RS01330 () | 99036..99506 | - | 471 | WP_004144067.1 | RES family NAD+ phosphorylase | Toxin Detail |
| GHA50_RS01335 () | 99503..99946 | - | 444 | WP_016528982.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| GHA50_RS01340 () | 100047..100554 | - | 508 | Protein_115 | DUF4113 domain-containing protein | - |
| GHA50_RS01345 () | 100663..100884 | - | 222 | WP_016528984.1 | DUF2188 domain-containing protein | - |
| GHA50_RS01350 () | 101029..101184 | - | 156 | WP_016528985.1 | hypothetical protein | - |
| GHA50_RS01355 () | 101259..101636 | - | 378 | Protein_118 | TonB-dependent receptor | - |
| GHA50_RS01360 () | 101633..101995 | - | 363 | Protein_119 | RNA polymerase subunit sigma | - |
| GHA50_RS01375 () | 103870..104064 | + | 195 | Protein_121 | IS66 family transposase ISEc23 | Transposase |
| GHA50_RS01380 () | 104219..105451 | + | 1233 | WP_016529501.1 | phosphoadenosine phosphosulfate reductase | - |
| GHA50_RS01385 () | 105436..106080 | + | 645 | WP_153459096.1 | ParB N-terminal domain-containing protein | - |
| GHA50_RS01390 () | 106122..106333 | + | 212 | Protein_124 | IS110 family transposase ISCps4 | Transposase |
| GHA50_RS01395 () | 106430..107545 | + | 1116 | WP_016529499.1 | Elloramycin glycosyltransferase ElmGT | VF |
| GHA50_RS01400 () | 107691..111335 | + | 3645 | WP_153459097.1 | Multidrug efflux ATP-binding/permease protein | VF |
| GHA50_RS01405 () | 111441..112670 | + | 1230 | WP_115223709.1 | Enterochelin esterase | VF |
| GHA50_RS01410 () | 113130..115304 | + | 2175 | WP_153459098.1 | Ferric enterobactin receptor | VF |
| GHA50_RS01415 () | 115737..116630 | - | 894 | WP_153459099.1 | DMT family transporter | - |
| GHA50_RS01420 () | 116703..117253 | - | 551 | Protein_130 | DNA-binding response regulator | - |
| GHA50_RS01425 () | 117647..118276 | - | 630 | Protein_131 | mucoid phenotype A regulator RmpA | - |
| GHA50_RS01430 () | 118817..119470 | + | 654 | WP_011251259.1 | class I SAM-dependent methyltransferase | - |
| GHA50_RS01435 () | 119547..119813 | - | 267 | Protein_133 | IS3 family transposase ISEcB1 | Transposase |
| GHA50_RS01440 () | 119824..120512 | - | 689 | Protein_134 | IS1 family transposase | - |
| GHA50_RS01445 () | 120644..120760 | + | 117 | Protein_135 | IS3 family transposase ISYpe1 | Transposase |
| GHA50_RS01450 () | 120984..122000 | - | 1017 | WP_153459062.1 | IS110 family transposase ISKpn2 | Transposase |
| GHA50_RS01455 () | 122067..122995 | + | 929 | Protein_137 | IS3 family transposase | - |
| GHA50_RS01460 () | 122949..123580 | + | 632 | Protein_138 | DUF4113 domain-containing protein | - |
| GHA50_RS01465 () | 123659..123887 | + | 229 | Protein_139 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| GHA50_RS01470 () | 124487..125458 | - | 972 | WP_004117790.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| GHA50_RS01475 () | 125458..126624 | - | 1167 | WP_023287153.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|