MGE detailed information

MGE type: Conjugative plasmid        MGE length: 179179 bp
Accession: NZ_CP043935        Location: 1..179179         Organism: Klebsiella pneumoniae strain 555       Replicon: plasmid pSCKLB555-3


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F2X40_RS28310 () 13..774 - 762 Protein_1 ATP-binding cassette domain-containing protein -
F2X40_RS28315 () 1037..1373 - 337 Protein_2 hypothetical protein -
F2X40_RS30615 () 1617..1871 - 255 Protein_3 hypothetical protein -
F2X40_RS28330 () 2452..2934 + 483 WP_150102520.1 hypothetical protein -
F2X40_RS28335 () 2952..3233 + 282 WP_150102521.1 hypothetical protein -
F2X40_RS28340 () 3245..3430 + 186 WP_150102522.1 hypothetical protein -
F2X40_RS28345 () 3789..4334 + 546 WP_001165114.1 hypothetical protein -
F2X40_RS28350 () 4491..4905 - 415 Protein_8 type II toxin-antitoxin system VapC family toxin -
F2X40_RS28355 () 4883..5125 - 243 Protein_9 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
F2X40_RS28360 () 5408..6969 + 1562 Protein_10 AAA family ATPase -
F2X40_RS28365 () 7026..7895 - 870 WP_000253407.1 hypothetical protein -
F2X40_RS28370 () 7897..8978 - 1082 Protein_12 transcriptional regulator -
F2X40_RS28375 () 9276..10208 - 933 WP_000991830.1 hypothetical protein -
F2X40_RS28380 () 10212..11203 - 992 Protein_14 nucleotidyltransferase -
F2X40_RS28390 () 11882..12232 + 351 WP_000493378.1 hypothetical protein -
F2X40_RS28400 () 13012..13788 + 777 WP_000015958.1 site-specific integrase -
F2X40_RS30620 () 14227..14330 - 104 Protein_17 hypothetical protein -
F2X40_RS28410 () 14544..14732 + 189 WP_000957857.1 hypothetical protein -
F2X40_RS28415 () 14732..15925 + 1194 Protein_19 IS91 family transposase -
F2X40_RS28420 () 16408..16794 - 387 WP_190294488.1 DNA distortion polypeptide 3 -
F2X40_RS28425 () 16830..17797 + 968 Protein_21 IS5 family transposase IS903B Transposase
F2X40_RS28430 () 17963..18407 - 445 Protein_22 hypothetical protein -
F2X40_RS28435 () 18411..19247 - 837 Protein_23 replication initiation protein -
F2X40_RS28440 () 19268..20102 - 835 Protein_24 replication initiation protein -
F2X40_RS28450 () 21335..21586 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin Detail
F2X40_RS28455 () 21576..21857 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
F2X40_RS28460 () 22095..22187 - 93 Protein_27 IS6 family transposase -
F2X40_RS28465 () 22353..23558 - 1206 Protein_28 IS91 family transposase IS1294 Transposase
F2X40_RS28470 () 23558..23746 - 189 WP_000957857.1 hypothetical protein -
F2X40_RS28475 () 23866..25294 + 1429 Protein_30 IS4-like element IS50R family transposase -
F2X40_RS28480 () 25323..26117 + 795 WP_000572405.1 Aminoglycoside 3'-phosphotransferase ARG
F2X40_RS28485 () 26138..26374 + 237 Protein_32 hypothetical protein -
F2X40_RS28490 () 26424..27128 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
F2X40_RS28495 () 27217..27696 + 480 WP_000888203.1 Rrf2 family transcriptional regulator -
F2X40_RS28500 () 27727..30903 - 3177 Protein_35 multidrug efflux RND transporter permease subunit OqxB -
F2X40_RS28505 () 30927..32094 - 1168 Protein_36 multidrug efflux RND transporter periplasmic adaptor subunit OqxA -
F2X40_RS28510 () 32413..33114 + 702 Protein_37 IS6 family transposase IS15DI Transposase
F2X40_RS28520 () 33166..34924 + 1759 Protein_38 Tn3 family transposase TnpA_ISPa38 Transposase
F2X40_RS28525 () 35003..36004 + 1002 Protein_39 IS110 family transposase IS5075 Transposase
F2X40_RS28530 () 36186..36326 - 141 WP_150102523.1 DUF4102 domain-containing protein -
F2X40_RS28540 () 36689..37502 + 814 Protein_41 Dihydropteroate synthase ARG
F2X40_RS28545 () 37563..38364 + 802 Protein_42 aminoglycoside O-phosphotransferase APH(3'')-Ib -
F2X40_RS28550 () 38364..39200 + 837 WP_000480968.1 aminoglycoside O-phosphotransferase APH(6)-Id -
F2X40_RS28560 () 39506..39751 + 246 WP_058914914.1 hypothetical protein -
F2X40_RS28565 () 39780..40430 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
F2X40_RS28570 () 40553..41734 + 1182 WP_150102524.1 Tetracycline resistance protein, class C ARG
F2X40_RS28575 () 41701..41889 - 189 Protein_47 IS91 family transposase -
F2X40_RS28580 () 42001..42306 - 306 WP_001255015.1 HTH-type transcriptional regulator CynR VF
F2X40_RS28585 () 42334..43545 - 1212 WP_150102525.1 Bicyclomycin resistance protein ARG
F2X40_RS28590 () 43761..44645 - 885 WP_021598067.1 DUF3363 domain-containing protein -
F2X40_RS28595 () 44676..46169 - 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
F2X40_RS28600 () 46380..46604 - 225 WP_000743213.1 hypothetical protein -
F2X40_RS28605 () 46601..47338 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
F2X40_RS30625 () 47824..47964 - 141 WP_001044210.1 hypothetical protein -
F2X40_RS28615 () 47970..48673 - 704 Protein_55 IS6 family transposase IS15DI Transposase
F2X40_RS28620 () 48945..49622 + 678 Protein_56 IS91 family transposase ISAzo26 Transposase
F2X40_RS28625 () 49674..49801 + 128 Protein_57 IS6 family transposase -
F2X40_RS28630 () 49970..50440 + 471 Protein_58 Tn3 family transposase TnpA_Tn3 Transposase
F2X40_RS28635 () 50476..50891 - 416 Protein_59 IS1 family transposase IS1R Transposase
F2X40_RS28640 () 51140..51541 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
F2X40_RS28645 () 51474..51731 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
F2X40_RS28650 () 51824..52477 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
F2X40_RS28660 () 53416..54273 - 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
F2X40_RS28665 () 54266..54340 - 75 WP_001375168.1 RepA leader peptide Tap -
F2X40_RS28675 () 54585..54833 - 249 WP_000083837.1 replication regulatory protein RepA -
F2X40_RS28680 () 55117..55266 - 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 55311..55370 + 60 NuclAT_1 - -
- () 55311..55370 + 60 NuclAT_1 - -
- () 55311..55370 + 60 NuclAT_1 - -
- () 55311..55370 + 60 NuclAT_1 - -
F2X40_RS28690 () 55571..55801 - 231 WP_001736714.1 hypothetical protein -
F2X40_RS28695 () 55965..56564 - 600 WP_032083981.1 hypothetical protein -
F2X40_RS28700 () 56950..57150 - 201 WP_015059022.1 hypothetical protein -
F2X40_RS28705 () 57282..57842 - 561 WP_000139328.1 fertility inhibition protein FinO -
F2X40_RS28710 () 57897..58643 - 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
F2X40_RS28715 () 58663..63933 - 5271 WP_072740640.1 Multifunctional conjugation protein TraI Relaxase
F2X40_RS28720 () 63933..66176 - 2244 WP_072646483.1 type IV conjugative transfer system coupling protein TraD -
F2X40_RS28725 () 66227..66964 - 738 WP_015059020.1 hypothetical protein -
F2X40_RS28730 () 67167..67898 - 732 WP_021559024.1 complement resistance protein TraT -
F2X40_RS28735 () 67923..68444 - 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
F2X40_RS28740 () 68477..71293 - 2817 WP_015059018.1 conjugal transfer mating pair stabilization protein TraG -
F2X40_RS28745 () 71290..72663 - 1374 WP_000944325.1 conjugal transfer protein TraH -
F2X40_RS28750 () 72650..73042 - 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
F2X40_RS28755 () 72996..73370 - 375 WP_071776752.1 P-type conjugative transfer protein TrbJ -
F2X40_RS28760 () 73300..73845 - 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
F2X40_RS28765 () 73832..74113 - 282 WP_000549793.1 type-F conjugative transfer system pilin chaperone TraQ -
F2X40_RS28770 () 74229..74978 - 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
F2X40_RS28775 () 74965..75222 - 258 WP_053913405.1 conjugal transfer protein TrbE -
F2X40_RS28780 () 75249..77099 - 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
F2X40_RS28785 () 77096..77518 - 423 WP_001229309.1 HNH endonuclease -
F2X40_RS28790 () 77544..77915 - 372 WP_000056336.1 hypothetical protein -
F2X40_RS28795 () 77912..78550 - 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
F2X40_RS28800 () 78577..79098 - 522 WP_015059014.1 hypothetical protein -
F2X40_RS28805 () 79161..79469 - 309 WP_000412447.1 hypothetical protein -
F2X40_RS28810 () 79496..80488 - 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
F2X40_RS28815 () 80485..81117 - 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
F2X40_RS28820 () 81114..81500 - 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
F2X40_RS28825 () 81497..84124 - 2628 WP_015059012.1 type IV secretion system protein TraC -
F2X40_RS28830 () 84284..84505 - 222 WP_001278692.1 conjugal transfer protein TraR -
F2X40_RS28835 () 84640..85155 - 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
F2X40_RS28840 () 85152..85403 - 252 WP_001038341.1 conjugal transfer protein TrbG -
F2X40_RS28845 () 85415..85645 - 231 WP_001352845.1 conjugal transfer protein TrbD -
F2X40_RS28850 () 85599..86189 - 591 WP_000002778.1 conjugal transfer protein TraP -
F2X40_RS28855 () 86179..86916 - 738 Protein_100 F-type conjugal transfer pilus assembly protein TraB -
F2X40_RS28860 () 86982..87685 + 704 Protein_101 IS6 family transposase IS15DI Transposase
F2X40_RS28865 () 87738..88433 - 696 Protein_102 conjugal transfer protein TraB -
F2X40_RS28870 () 88433..89137 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
F2X40_RS28875 () 89148..89714 - 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
F2X40_RS28880 () 89736..90047 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
F2X40_RS28885 () 90062..90427 - 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
F2X40_RS28890 () 90461..90688 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
F2X40_RS28895 () 90782..91468 - 687 WP_015059009.1 PAS domain-containing protein -
F2X40_RS28900 () 91659..92042 - 384 WP_000124981.1 relaxosome protein TraM -
F2X40_RS28905 () 92319..92966 + 648 WP_015059008.1 hypothetical protein VF
F2X40_RS28910 () 93263..94084 - 822 WP_001234445.1 DUF945 domain-containing protein -
F2X40_RS28915 () 94195..94491 - 297 WP_001272251.1 hypothetical protein -
F2X40_RS30630 () 94791..95168 + 378 Protein_113 hypothetical protein -
F2X40_RS28935 () 95406..95564 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 95608..95832 - 225 NuclAT_0 - -
- () 95608..95832 - 225 NuclAT_0 - -
- () 95608..95832 - 225 NuclAT_0 - -
- () 95608..95832 - 225 NuclAT_0 - -
F2X40_RS28940 () 95844..96563 - 720 WP_001276217.1 plasmid SOS inhibition protein A -
F2X40_RS28945 () 96560..96994 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
F2X40_RS28950 () 97063..99086 - 2024 Protein_117 ParB/RepB/Spo0J family partition protein -
F2X40_RS28955 () 99147..99380 - 234 WP_000006003.1 DUF905 family protein -
F2X40_RS28960 () 99438..99965 - 528 WP_000290834.1 single-stranded DNA-binding protein -
F2X40_RS28985 () 100796..101359 - 564 WP_015059007.1 class I SAM-dependent methyltransferase -
F2X40_RS28990 () 101406..102767 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
F2X40_RS28995 () 102819..103049 - 231 WP_000218642.1 hypothetical protein -
F2X40_RS29005 () 104449..106116 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
F2X40_RS29010 () 106430..106621 - 192 WP_001027493.1 hypothetical protein -
F2X40_RS29015 () 106618..107040 - 423 WP_000271762.1 DUF1380 family protein -
F2X40_RS29020 () 107087..107512 - 426 WP_001198928.1 antirestriction protein -
F2X40_RS30635 () 107930..108706 - 777 WP_001383963.1 hypothetical protein -
F2X40_RS29035 () 108757..109191 - 435 WP_000274503.1 DUF1380 family protein -
F2X40_RS29040 () 109205..109426 - 222 WP_001104881.1 hypothetical protein -
F2X40_RS29045 () 109427..110110 - 684 WP_000085883.1 DNA methylase -
F2X40_RS29055 () 110187..110480 - 294 WP_032146011.1 hypothetical protein -
F2X40_RS29060 () 110627..111589 + 963 WP_000959884.1 plasmid segregation protein ParM -
F2X40_RS29065 () 111592..111942 + 351 WP_000361389.1 plasmid partitioning/stability family protein -
F2X40_RS29070 () 112065..112346 - 282 WP_001333089.1 hypothetical protein -
F2X40_RS29075 () 112474..112708 - 235 Protein_135 type II toxin-antitoxin system RelE/ParE family toxin -
F2X40_RS30640 () 114157..114222 - 66 Protein_136 IS1 family transposase -
F2X40_RS29095 () 114288..114992 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
F2X40_RS29100 () 115414..116289 + 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
F2X40_RS29105 () 116336..116812 - 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
F2X40_RS29110 () 117071..117814 - 744 Protein_140 Beta-lactamase TEM ARG
F2X40_RS29115 () 117864..118566 - 703 Protein_141 IS6 family transposase IS15DI Transposase
F2X40_RS29120 () 118952..119368 + 417 WP_014839980.1 Glutathione transferase FosA ARG
F2X40_RS29125 () 119373..119891 - 519 WP_014839979.1 hypothetical protein -
F2X40_RS29130 () 119891..120679 - 789 WP_014839978.1 winged helix-turn-helix domain-containing protein -
F2X40_RS29135 () 120699..121169 - 471 WP_049824851.1 TetR family transcriptional regulator -
F2X40_RS29145 () 121179..121881 - 703 Protein_146 IS6-like element IS26 family transposase -
F2X40_RS29155 () 122118..122441 - 324 WP_001175594.1 helix-turn-helix domain-containing protein -
F2X40_RS29160 () 122546..122656 + 111 Protein_148 permease -
F2X40_RS29165 () 122688..123655 + 968 Protein_149 IS5 family transposase IS903B Transposase
F2X40_RS29170 () 123713..124648 + 936 Protein_150 permease -
F2X40_RS29175 () 124941..125558 - 618 WP_000521603.1 hypothetical protein -
F2X40_RS29180 () 125749..127305 - 1557 WP_024126035.1 AAA family ATPase -
F2X40_RS29185 () 127567..128157 - 591 WP_000194575.1 hypothetical protein -
F2X40_RS29190 () 128157..128414 - 258 WP_000343085.1 hypothetical protein -
F2X40_RS29195 () 128768..130906 + 2139 WP_000350635.1 AAA family ATPase -
F2X40_RS29200 () 131068..131484 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
F2X40_RS29205 () 131481..131711 - 231 WP_001261287.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
F2X40_RS29215 () 132019..133584 + 1566 WP_000741348.1 ATP-binding protein -
F2X40_RS29220 () 133641..134508 - 868 Protein_159 hypothetical protein -
F2X40_RS29225 () 134510..135598 - 1089 WP_000952231.1 hypothetical protein -
F2X40_RS29230 () 135895..136814 - 920 Protein_161 hypothetical protein -
F2X40_RS29235 () 136818..137812 - 995 Protein_162 nucleotidyltransferase -
F2X40_RS29245 () 138492..138839 + 348 Protein_163 hypothetical protein -
F2X40_RS29250 () 138890..139633 + 744 WP_000129823.1 hypothetical protein -
F2X40_RS29255 () 139630..140406 + 777 WP_000015958.1 site-specific integrase -
F2X40_RS29260 () 140464..140721 - 258 WP_000764642.1 hypothetical protein -
F2X40_RS30645 () 140850..140954 - 105 WP_032409716.1 hypothetical protein -
F2X40_RS29265 () 141184..141372 + 189 WP_000957857.1 hypothetical protein -
F2X40_RS29270 () 141382..142577 + 1196 Protein_169 IS91 family transposase ISSbo1 Transposase
F2X40_RS29275 () 143063..143447 - 385 Protein_170 DNA distortion polypeptide 3 -
F2X40_RS29280 () 143483..144447 + 965 Protein_171 IS5 family transposase IS903B Transposase
F2X40_RS29285 () 144611..145057 - 447 WP_001074384.1 hypothetical protein -
F2X40_RS29290 () 145061..145903 - 843 WP_000435064.1 replication initiation protein -
F2X40_RS29295 () 145924..146762 - 839 Protein_174 replication initiation protein -
F2X40_RS29315 () 148225..148506 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin -
F2X40_RS29320 () 148745..148837 - 93 Protein_176 IS6 family transposase -
F2X40_RS29325 () 149003..150199 - 1197 Protein_177 IS91 family transposase ISSbo1 Transposase
F2X40_RS29330 () 150209..150397 - 189 WP_000957857.1 hypothetical protein -
F2X40_RS29335 () 150514..151943 + 1430 Protein_179 IS4 family transposase IS50R Transposase
F2X40_RS29340 () 151972..152766 + 795 WP_150102527.1 Aminoglycoside 3'-phosphotransferase ARG
F2X40_RS29345 () 152787..153019 + 233 Protein_181 hypothetical protein -
F2X40_RS29350 () 153069..153670 + 602 Protein_182 IS6 family transposase IS15DI Transposase
F2X40_RS29355 () 153852..154329 + 478 Protein_183 Rrf2 family transcriptional regulator -
F2X40_RS29360 () 154399..157549 - 3151 Protein_184 Efflux pump membrane transporter BepE VF
F2X40_RS29365 () 157573..158748 - 1176 WP_063865358.1 Efflux pump periplasmic linker BepF VF
F2X40_RS29370 () 159067..159769 + 703 Protein_186 IS6 family transposase -
F2X40_RS29380 () 159821..161587 + 1767 Protein_187 Tn3 family transposase TnpA_ISPa38 Transposase
F2X40_RS29385 () 161666..162668 + 1003 Protein_188 IS110 family transposase IS5075 Transposase
F2X40_RS29390 () 162850..163026 - 177 WP_000954592.1 Arm DNA-binding domain-containing protein -
F2X40_RS29400 () 163356..164171 + 816 WP_001043260.1 Dihydropteroate synthase ARG
F2X40_RS29405 () 164232..165033 + 802 Protein_191 Aminoglycoside 3'-phosphotransferase ARG
F2X40_RS29410 () 165033..165868 + 836 Protein_192 hypothetical protein ARG
F2X40_RS29420 () 166165..166410 + 246 WP_150102528.1 relaxase -
F2X40_RS29425 () 166439..167089 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
F2X40_RS29430 () 167195..168388 + 1194 WP_150102529.1 Tetracycline resistance protein, class C ARG
F2X40_RS29435 () 168355..168543 - 189 Protein_196 IS91 family transposase -
F2X40_RS29440 () 168655..168960 - 306 WP_001255015.1 HTH-type transcriptional regulator CynR VF
F2X40_RS29445 () 168988..170200 - 1213 Protein_198 Inner membrane transport protein YdhC ARG
F2X40_RS29450 () 170417..171180 - 764 Protein_199 DUF3363 domain-containing protein -
F2X40_RS29455 () 171323..172385 - 1063 Protein_200 IS91 family transposase ISVsa3 Transposase
F2X40_RS29460 () 172283..172802 - 520 Protein_201 transposase zinc-binding domain-containing protein -
F2X40_RS29465 () 173043..173230 - 188 Protein_202 hypothetical protein -
F2X40_RS29470 () 173227..173957 - 731 Protein_203 Tn3 family transposase TnpR_TnEc1 Transposase
F2X40_RS29475 () 174059..174549 + 491 Protein_204 hypothetical protein -
F2X40_RS29480 () 174625..175276 - 652 Protein_205 IS6 family transposase -
F2X40_RS30650 () 175548..176219 + 672 Protein_206 integron integrase -
F2X40_RS29495 () 176284..176959 + 676 Protein_207 IS6 family transposase -
F2X40_RS29500 () 177025..177516 + 492 Protein_208 Tn3 family transposase -
F2X40_RS29505 () 177584..177995 - 412 Protein_209 IS1 family transposase -
F2X40_RS29510 () 178231..178624 - 394 Protein_210 type II toxin-antitoxin system toxin endoribonuclease PemK -
F2X40_RS29515 () 178557..178775 - 219 WP_001340587.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance