MGE detailed information
MGE type: Conjugative plasmid MGE length: 145329 bp
Accession: NZ_CP038326 Location: 1..145329 Organism: Escherichia coli O157:H7 strain NE 1169-1 Replicon: plasmid pNE1169-3
Accession: NZ_CP038326 Location: 1..145329 Organism: Escherichia coli O157:H7 strain NE 1169-1 Replicon: plasmid pNE1169-3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4U74_RS27175 () | 27..1520 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| E4U74_RS27180 () | 1731..1955 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| E4U74_RS27185 () | 1952..2689 | - | 738 | WP_001366550.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| E4U74_RS27190 () | 3175..3315 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| E4U74_RS27195 () | 3321..4025 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4U74_RS27200 () | 4091..4312 | + | 222 | Protein_5 | IS6 family transposase IS15 | Transposase |
| E4U74_RS27205 () | 4609..5166 | + | 558 | WP_001162012.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| E4U74_RS27210 () | 5169..8141 | + | 2973 | WP_001138073.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| E4U74_RS27215 () | 8366..8575 | + | 210 | Protein_8 | hypothetical protein | - |
| E4U74_RS27220 () | 8633..8980 | + | 348 | WP_042849136.1 | hypothetical protein | - |
| E4U74_RS27225 () | 8980..9540 | + | 561 | WP_001143450.1 | Dihydrofolate reductase | ARG |
| E4U74_RS27230 () | 9521..9967 | + | 447 | WP_001274976.1 | hypothetical protein | - |
| E4U74_RS27235 () | 9993..10610 | + | 618 | WP_000256638.1 | ATP-dependent Clp protease proteolytic subunit | - |
| E4U74_RS27240 () | 10732..12273 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| E4U74_RS27245 () | 12678..13517 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| E4U74_RS27250 () | 13511..13858 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| E4U74_RS27255 () | 14022..14813 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| E4U74_RS27260 () | 14959..15756 | + | 798 | Protein_17 | IS91 family transposase ISAzo26 | Transposase |
| E4U74_RS27265 () | 15809..16513 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4U74_RS27270 () | 16820..16999 | + | 180 | Protein_19 | helix-turn-helix transcriptional regulator | - |
| E4U74_RS27275 () | 17064..17768 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4U74_RS27280 () | 17983..18480 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| E4U74_RS27285 () | 18483..18971 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| E4U74_RS27290 () | 19068..19403 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| E4U74_RS27295 () | 19418..19888 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| E4U74_RS27300 () | 19881..20252 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| E4U74_RS27305 () | 20263..20457 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| E4U74_RS27310 () | 20798..21346 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| E4U74_RS27315 () | 21509..21859 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| E4U74_RS27320 () | 21864..22166 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin Detail |
| E4U74_RS27325 () | 22193..22486 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| E4U74_RS27330 () | 22574..22846 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| E4U74_RS27335 () | 22904..23431 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| E4U74_RS27340 () | 23662..24519 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| E4U74_RS27345 () | 24506..24736 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| E4U74_RS27350 () | 24736..25254 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| E4U74_RS27355 () | 25251..25697 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| E4U74_RS27360 () | 25697..26056 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| E4U74_RS27365 () | 26113..26541 | - | 429 | WP_000591074.1 | hypothetical protein | - |
| E4U74_RS27370 () | 26575..27435 | - | 861 | WP_000139698.1 | DsbA family protein | - |
| E4U74_RS27375 () | 27451..28410 | - | 960 | WP_000829616.1 | S49 family peptidase | - |
| E4U74_RS27380 () | 28410..29264 | - | 855 | WP_000539392.1 | hypothetical protein | - |
| E4U74_RS27385 () | 29269..29562 | - | 294 | WP_001370730.1 | hypothetical protein | - |
| E4U74_RS27390 () | 29573..30046 | - | 474 | WP_000057877.1 | hypothetical protein | - |
| E4U74_RS27395 () | 30143..30664 | - | 522 | WP_000805800.1 | hypothetical protein | - |
| E4U74_RS27400 () | 30667..31188 | - | 522 | WP_000393785.1 | hypothetical protein | - |
| E4U74_RS27405 () | 31193..31801 | - | 609 | WP_000849071.1 | hypothetical protein | - |
| E4U74_RS27410 () | 32070..33185 | + | 1116 | WP_000946102.1 | phosphoadenosine phosphosulfate reductase family protein | - |
| E4U74_RS27415 () | 33203..33637 | + | 435 | WP_000883925.1 | hypothetical protein | - |
| E4U74_RS27420 () | 34674..35774 | - | 1101 | WP_000350011.1 | plasmid replication protein | - |
| E4U74_RS27425 () | 35759..36046 | - | 288 | WP_000127321.1 | hypothetical protein | - |
| E4U74_RS27430 () | 36051..36590 | - | 540 | WP_001447712.1 | hypothetical protein | - |
| E4U74_RS27435 () | 37089..38072 | + | 984 | WP_000077458.1 | ParM/StbA family protein | - |
| E4U74_RS27440 () | 38089..38382 | + | 294 | WP_000919078.1 | hypothetical protein | - |
| E4U74_RS27445 () | 38384..38803 | + | 420 | WP_000651490.1 | H-NS histone family protein | - |
| E4U74_RS27450 () | 38863..39414 | - | 552 | WP_001020646.1 | hypothetical protein | - |
| E4U74_RS27455 () | 39411..40019 | - | 609 | WP_000891157.1 | hypothetical protein | - |
| E4U74_RS27460 () | 40030..40563 | - | 534 | WP_032064504.1 | transglycosylase SLT domain-containing protein | - |
| E4U74_RS27465 () | 40563..40835 | - | 273 | WP_000356489.1 | helix-turn-helix domain-containing protein | - |
| E4U74_RS27470 () | 41551..41913 | + | 363 | WP_000683483.1 | hypothetical protein | - |
| E4U74_RS27475 () | 41951..45565 | - | 3615 | WP_000534551.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| E4U74_RS27480 () | 45578..47011 | - | 1434 | WP_000256129.1 | conjugal transfer protein TraH | - |
| E4U74_RS27485 () | 47013..48053 | - | 1041 | WP_001326396.1 | conjugal transfer protein TraF | - |
| E4U74_RS27490 () | 48164..49675 | - | 1512 | WP_000811656.1 | ATP-dependent helicase | - |
| E4U74_RS27495 () | 49962..51002 | - | 1041 | WP_000101568.1 | DNA-binding protein | - |
| E4U74_RS27500 () | 51155..52030 | - | 876 | WP_001097010.1 | DNA replication terminus site-binding protein | - |
| E4U74_RS27505 () | 52357..52848 | - | 492 | WP_000139717.1 | hypothetical protein | - |
| E4U74_RS27510 () | 52845..53714 | - | 870 | WP_000997323.1 | 3'-5' exonuclease | - |
| E4U74_RS27515 () | 53719..54729 | - | 1011 | WP_000543934.1 | IS91 family transposase ISWz1 | Transposase |
| E4U74_RS27520 () | 54732..55268 | - | 537 | WP_000949433.1 | hypothetical protein | - |
| E4U74_RS27525 () | 55567..55848 | - | 282 | WP_000575657.1 | hypothetical protein | - |
| E4U74_RS27530 () | 56110..56712 | + | 603 | WP_000278322.1 | hypothetical protein | - |
| E4U74_RS27535 () | 56728..57180 | - | 453 | WP_000791469.1 | hypothetical protein | - |
| E4U74_RS27540 () | 57347..57646 | - | 300 | WP_011872911.1 | hypothetical protein | - |
| E4U74_RS27545 () | 57694..57936 | - | 243 | WP_000750746.1 | hypothetical protein | - |
| E4U74_RS27550 () | 57941..58213 | - | 273 | WP_000787563.1 | MafI family immunity protein | - |
| E4U74_RS27555 () | 58210..62364 | - | 4155 | WP_014342219.1 | Putative deoxyribonuclease RhsC | VF |
| E4U74_RS27560 () | 62605..63330 | - | 726 | WP_000988732.1 | hypothetical protein | - |
| E4U74_RS27565 () | 63444..63818 | - | 375 | WP_000868821.1 | hypothetical protein | - |
| E4U74_RS27570 () | 63939..64055 | - | 117 | WP_000338626.1 | hypothetical protein | - |
| E4U74_RS27575 () | 64065..64304 | - | 240 | WP_000714162.1 | permease | - |
| E4U74_RS27580 () | 64377..64655 | - | 279 | WP_000268337.1 | hypothetical protein | - |
| E4U74_RS27585 () | 64642..66369 | - | 1728 | WP_000122923.1 | toprim domain-containing protein | - |
| E4U74_RS27590 () | 66547..66933 | - | 387 | WP_001077335.1 | hypothetical protein | - |
| E4U74_RS27595 () | 67391..68242 | - | 852 | WP_000595210.1 | hypothetical protein | - |
| E4U74_RS27600 () | 68317..68874 | - | 558 | WP_000064431.1 | pyruvate dehydrogenase | - |
| E4U74_RS27605 () | 68948..69166 | - | 219 | WP_000260293.1 | hypothetical protein | - |
| E4U74_RS27610 () | 69180..69449 | - | 270 | WP_000184110.1 | hypothetical protein | - |
| E4U74_RS27615 () | 69442..70047 | - | 606 | WP_000071870.1 | 5'-deoxynucleotidase | - |
| E4U74_RS27620 () | 70119..70322 | - | 204 | WP_000050848.1 | hypothetical protein | - |
| E4U74_RS27625 () | 70602..71930 | + | 1329 | WP_000547316.1 | IS4 family transposase IS4 | Transposase |
| E4U74_RS27630 () | 71962..74415 | - | 2454 | WP_001187970.1 | phosphoadenosine phosphosulfate reductase | - |
| E4U74_RS27635 () | 74503..74889 | - | 387 | WP_000042274.1 | hypothetical protein | - |
| E4U74_RS27640 () | 75122..75676 | - | 555 | WP_001093868.1 | hypothetical protein | - |
| E4U74_RS27645 () | 75750..76181 | - | 432 | WP_000687894.1 | hypothetical protein | - |
| E4U74_RS27650 () | 76242..77867 | - | 1626 | WP_000201432.1 | DNA cytosine methyltransferase | - |
| E4U74_RS27655 () | 77945..78247 | - | 303 | WP_000410925.1 | hypothetical protein | - |
| E4U74_RS27660 () | 78325..78669 | - | 345 | WP_000209093.1 | hypothetical protein | - |
| E4U74_RS27665 () | 78861..79238 | - | 378 | WP_001337696.1 | hypothetical protein | - |
| E4U74_RS27670 () | 79283..79474 | - | 192 | WP_000651508.1 | hypothetical protein | - |
| E4U74_RS27675 () | 79492..79734 | + | 243 | WP_002210529.1 | hypothetical protein | - |
| E4U74_RS27680 () | 79812..80264 | - | 453 | WP_001176699.1 | hypothetical protein | - |
| E4U74_RS27685 () | 80254..80643 | - | 390 | WP_000026577.1 | hypothetical protein | - |
| E4U74_RS27690 () | 80705..80929 | - | 225 | WP_001102700.1 | 2Fe-2S ferredoxin-like protein | - |
| E4U74_RS27695 () | 80995..81879 | - | 885 | WP_000477209.1 | hypothetical protein | - |
| E4U74_RS27700 () | 81953..82453 | - | 501 | WP_000793769.1 | hypothetical protein | - |
| E4U74_RS27705 () | 82544..83083 | - | 540 | WP_000018872.1 | hypothetical protein | - |
| E4U74_RS27710 () | 83348..83683 | - | 336 | WP_001071288.1 | hypothetical protein | - |
| E4U74_RS27715 () | 83745..85541 | - | 1797 | WP_021598075.1 | VWA domain-containing protein | - |
| E4U74_RS27720 () | 85626..86903 | - | 1278 | WP_000170086.1 | DUF3150 domain-containing protein | - |
| E4U74_RS27725 () | 87103..88113 | - | 1011 | WP_000706865.1 | YqaJ viral recombinase family protein | - |
| E4U74_RS27730 () | 88176..89165 | - | 990 | WP_001282585.1 | phage recombination protein Bet | - |
| E4U74_RS27735 () | 89260..89790 | - | 531 | WP_000987165.1 | single-stranded DNA-binding protein | - |
| E4U74_RS27740 () | 89851..90759 | - | 909 | WP_000739139.1 | hypothetical protein | - |
| E4U74_RS27745 () | 90770..91738 | - | 969 | WP_000085162.1 | CbbQ/NirQ/NorQ C-terminal domain-containing protein | - |
| E4U74_RS27750 () | 91958..92143 | - | 186 | WP_001186917.1 | hypothetical protein | - |
| E4U74_RS27755 () | 92447..92767 | - | 321 | WP_000547566.1 | hypothetical protein | - |
| E4U74_RS27760 () | 93061..93702 | + | 642 | WP_000796664.1 | hypothetical protein | - |
| E4U74_RS27765 () | 93825..94685 | + | 861 | WP_000709517.1 | hypothetical protein | - |
| E4U74_RS27770 () | 94724..97534 | - | 2811 | WP_001909286.1 | conjugal transfer mating pair stabilization protein TraN | - |
| E4U74_RS27775 () | 97638..98645 | - | 1008 | WP_000983283.1 | TraU family protein | - |
| E4U74_RS27780 () | 98642..99313 | - | 672 | WP_001337754.1 | EAL domain-containing protein | - |
| E4U74_RS27785 () | 99310..100575 | - | 1266 | WP_000621288.1 | conjugal transfer protein TraW | - |
| E4U74_RS27790 () | 100538..101068 | - | 531 | WP_001010738.1 | S26 family signal peptidase | - |
| E4U74_RS27795 () | 101065..101382 | - | 318 | WP_000351984.1 | hypothetical protein | - |
| E4U74_RS27800 () | 101397..103844 | - | 2448 | WP_000637386.1 | type IV secretion system protein TraC | - |
| E4U74_RS27805 () | 103841..104548 | - | 708 | WP_001259347.1 | DsbC family protein | - |
| E4U74_RS27810 () | 104697..110228 | - | 5532 | WP_000606833.1 | DUF4165 domain-containing protein | - |
| E4U74_RS27815 () | 110429..110821 | - | 393 | WP_000479535.1 | hypothetical protein | - |
| E4U74_RS27820 () | 110825..111403 | - | 579 | WP_000793435.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E4U74_RS27825 () | 111400..112713 | - | 1314 | WP_024131605.1 | conjugal transfer protein TraB | - |
| E4U74_RS27830 () | 112713..113630 | - | 918 | WP_000794249.1 | type-F conjugative transfer system secretin TraK | - |
| E4U74_RS27835 () | 113614..114240 | - | 627 | WP_001049716.1 | hypothetical protein | - |
| E4U74_RS27840 () | 114237..114518 | - | 282 | WP_000805625.1 | type IV conjugative transfer system protein TraL | - |
| E4U74_RS27845 () | 114663..115040 | - | 378 | WP_000509509.1 | hypothetical protein | - |
| E4U74_RS27850 () | 115364..116026 | - | 663 | WP_001231463.1 | hypothetical protein | - |
| E4U74_RS27855 () | 116026..116403 | - | 378 | WP_000869261.1 | hypothetical protein | - |
| E4U74_RS27860 () | 116413..116859 | - | 447 | WP_000122506.1 | hypothetical protein | - |
| E4U74_RS27865 () | 116869..117498 | - | 630 | WP_000743450.1 | DUF4400 domain-containing protein | - |
| E4U74_RS27870 () | 117455..118039 | - | 585 | WP_000332866.1 | hypothetical protein | - |
| E4U74_RS27875 () | 118050..119915 | - | 1866 | WP_000178856.1 | conjugative transfer system coupling protein TraD | - |
| E4U74_RS27880 () | 119912..122890 | - | 2979 | WP_001337757.1 | hypothetical protein | Relaxase |
| E4U74_RS27885 () | 123058..123675 | + | 618 | WP_001249396.1 | hypothetical protein | - |
| E4U74_RS27890 () | 123657..123890 | + | 234 | WP_001191892.1 | hypothetical protein | - |
| E4U74_RS27895 () | 123890..126082 | + | 2193 | WP_000366822.1 | DNA topoisomerase 3 | - |
| E4U74_RS27900 () | 126097..126585 | + | 489 | WP_000468105.1 | hypothetical protein | - |
| E4U74_RS27905 () | 126677..126976 | - | 300 | WP_000542259.1 | hypothetical protein | - |
| E4U74_RS27910 () | 127188..127805 | - | 618 | WP_000464631.1 | hypothetical protein | - |
| E4U74_RS27915 () | 127899..128117 | - | 219 | WP_000362482.1 | hypothetical protein | - |
| E4U74_RS27920 () | 128323..128979 | - | 657 | WP_000268551.1 | hypothetical protein | - |
| E4U74_RS27925 () | 128979..130406 | - | 1428 | WP_000936896.1 | DNA cytosine methyltransferase | - |
| E4U74_RS27930 () | 130410..130910 | - | 501 | WP_000647189.1 | hypothetical protein | - |
| E4U74_RS27935 () | 130919..131230 | - | 312 | WP_002210541.1 | hypothetical protein | - |
| E4U74_RS27940 () | 131236..131667 | - | 432 | WP_005507681.1 | hypothetical protein | - |
| E4U74_RS27945 () | 131735..132409 | - | 675 | WP_000344151.1 | thymidylate kinase | - |
| E4U74_RS27950 () | 132384..132665 | - | 282 | WP_000044824.1 | hypothetical protein | - |
| E4U74_RS27955 () | 132658..133035 | - | 378 | WP_001125905.1 | hypothetical protein | - |
| E4U74_RS27960 () | 133354..133497 | + | 144 | WP_000939033.1 | hypothetical protein | - |
| E4U74_RS27965 () | 133589..134224 | + | 636 | WP_000074431.1 | N-6 DNA methylase | - |
| E4U74_RS27970 () | 134277..134549 | - | 273 | WP_000703827.1 | helix-turn-helix domain-containing protein | - |
| E4U74_RS27975 () | 134598..135779 | - | 1182 | WP_001207227.1 | ParB/RepB/Spo0J family partition protein | - |
| E4U74_RS27980 () | 135783..136568 | - | 786 | WP_001151304.1 | Sporulation initiation inhibitor protein Soj | VF |
| E4U74_RS27985 () | 136742..137053 | - | 312 | WP_000338945.1 | hypothetical protein | - |
| E4U74_RS27990 () | 137360..138175 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| E4U74_RS27995 () | 138236..139039 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| E4U74_RS28000 () | 139039..139875 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| E4U74_RS28005 () | 140181..140423 | + | 243 | WP_000844627.1 | transposase | - |
| E4U74_RS28010 () | 140455..141105 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| E4U74_RS28015 () | 141211..142410 | + | 1200 | WP_000804063.1 | Tetracycline resistance protein, class C | ARG |
| E4U74_RS28020 () | 142377..142565 | - | 189 | Protein_169 | IS91 family transposase | - |
| E4U74_RS28025 () | 142677..142982 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| E4U74_RS28030 () | 143010..144224 | - | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
| E4U74_RS28035 () | 144441..145325 | - | 885 | WP_021598067.1 | DUF3363 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|