MGE detailed information

MGE type: Conjugative plasmid        MGE length: 122641 bp
Accession: NZ_CP023164        Location: 1..122641         Organism: Escherichia coli O22:H8 strain RM10809-3       Replicon: plasmid pRM10809-3


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLC88_RS00005 () 283..1086 - 804 WP_000899428.1 Outer membrane protein A VF
CLC88_RS00010 () 1111..5436 - 4326 WP_050864263.1 Autotransporter adhesin SadA VF
CLC88_RS00015 () 5572..5859 - 288 WP_050864264.1 Major pilu subunit operon regulatory protein PapB VF
CLC88_RS25565 () 5801..6052 + 252 WP_196497610.1 hypothetical protein -
CLC88_RS00020 () 6676..8232 + 1557 WP_050864262.1 L-lactate permease -
CLC88_RS00025 () 8282..9001 + 720 WP_044804124.1 (Fe-S)-binding protein -
CLC88_RS00030 () 9012..10427 + 1416 WP_000054160.1 iron-sulfur cluster-binding protein -
CLC88_RS00035 () 10432..11130 + 699 WP_000431492.1 lactate utilization protein C -
CLC88_RS00040 () 11171..11407 - 237 WP_001369996.1 hypothetical protein -
CLC88_RS00045 () 11475..11939 - 465 WP_077629759.1 IS3 family transposase ISKpn8 Transposase
CLC88_RS00050 () 12055..12366 - 312 WP_000204186.1 hypothetical protein -
CLC88_RS00055 () 12394..12585 - 192 WP_000264906.1 hypothetical protein -
CLC88_RS00060 () 12595..12960 - 366 WP_000997727.1 hypothetical protein -
CLC88_RS00065 () 13094..13303 + 210 WP_062896385.1 hypothetical protein -
CLC88_RS00070 () 13466..17367 - 3902 Protein_14 Serine protease EspP VF
CLC88_RS00075 () 17864..18250 - 387 WP_000598953.1 thermonuclease family protein -
CLC88_RS00080 () 18409..19086 + 678 WP_001158025.1 hypothetical protein -
CLC88_RS00085 () 19576..19896 - 321 WP_000220092.1 hypothetical protein -
CLC88_RS00090 () 19954..21116 - 1163 Protein_18 IS3-like element IS3 family transposase -
CLC88_RS25570 () 21183..21272 - 90 Protein_19 transposase -
CLC88_RS00095 () 21526..22908 + 1383 WP_136744503.1 autoagglutinating adhesin Saa -
CLC88_RS00100 () 23174..23323 + 150 WP_000539306.1 hypothetical protein -
CLC88_RS00105 () 23406..24521 + 1116 Protein_22 IS3 family transposase -
CLC88_RS00110 () 24829..26916 + 2088 WP_001223214.1 bifunctional siderophore receptor/adhesin Iha -
CLC88_RS00115 () 27177..27599 - 423 WP_001212725.1 Exc2 family lipoprotein -
CLC88_RS00120 () 27934..28116 - 183 Protein_25 IS110 family transposase -
CLC88_RS00125 () 28178..28366 + 189 Protein_26 IS66 family transposase IS682 Transposase
CLC88_RS00130 () 28420..28614 - 195 Protein_27 IS66 family transposase ISEc23 Transposase
CLC88_RS00135 () 29113..29301 - 189 WP_196497611.1 hypothetical protein -
CLC88_RS00140 () 29921..38734 - 8814 Protein_29 tRNA nuclease CdiA VF
CLC88_RS00145 () 38747..40513 - 1767 WP_050864233.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -
CLC88_RS00150 () 41128..41367 - 240 WP_000859018.1 MarR family transcriptional regulator -
CLC88_RS00155 () 42343..43200 - 858 WP_028985401.1 incFII family plasmid replication initiator RepA -
CLC88_RS00160 () 43193..43267 - 75 WP_062865987.1 RepA leader peptide Tap -
CLC88_RS00165 () 43503..43760 - 258 WP_000084404.1 replication regulatory protein RepA -
CLC88_RS00170 () 44044..44250 - 207 WP_032186826.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 44237..44298 + 62 NuclAT_1 - Antitoxin Detail
- () 44237..44298 + 62 NuclAT_1 - Antitoxin Detail
- () 44237..44298 + 62 NuclAT_1 - Antitoxin Detail
- () 44237..44298 + 62 NuclAT_1 - Antitoxin Detail
CLC88_RS25575 () 44473..44856 - 384 Protein_36 hypothetical protein -
CLC88_RS00180 () 44959..45418 - 460 Protein_37 thermonuclease family protein -
CLC88_RS00185 () 46161..46364 - 204 WP_032295436.1 hypothetical protein -
CLC88_RS00190 () 46519..47076 - 558 WP_028985402.1 fertility inhibition protein FinO -
CLC88_RS00195 () 47131..47877 - 747 WP_044804172.1 Multifunctional conjugation protein TraI Relaxase
CLC88_RS00205 () 47897..53164 - 5268 Protein_41 Multifunctional conjugation protein TraI Relaxase
CLC88_RS00210 () 53164..55369 - 2206 Protein_42 type IV conjugative transfer system coupling protein TraD -
CLC88_RS00215 () 55651..56130 - 480 WP_001473214.1 hypothetical protein -
CLC88_RS00220 () 56333..57064 - 732 WP_050878060.1 complement resistance protein TraT -
CLC88_RS00225 () 57577..60421 - 2845 Protein_45 conjugal transfer mating pair stabilization protein TraG -
CLC88_RS00230 () 60418..61791 - 1374 Protein_46 conjugal transfer protein TraH -
CLC88_RS00235 () 61778..62494 - 717 Protein_47 P-type conjugative transfer protein TrbJ -
CLC88_RS00240 () 62424..62969 - 546 WP_001457363.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CLC88_RS00245 () 62956..63246 - 291 WP_021521297.1 type-F conjugative transfer system pilin chaperone TraQ -
CLC88_RS00250 () 63642..63983 - 342 WP_000556797.1 conjugal transfer protein TrbA -
CLC88_RS00255 () 63997..64740 - 744 WP_001030373.1 type-F conjugative transfer system pilin assembly protein TraF -
CLC88_RS00260 () 64733..64990 - 258 WP_050878058.1 conjugal transfer protein TrbE -
CLC88_RS00265 () 65004..66838 - 1835 Protein_53 type-F conjugative transfer system mating-pair stabilization protein TraN -
CLC88_RS00270 () 66998..67378 - 381 WP_032206670.1 hypothetical protein -
CLC88_RS00275 () 67375..68013 - 639 WP_032305012.1 type-F conjugative transfer system pilin assembly protein TrbC -
CLC88_RS00280 () 68205..68444 + 240 WP_001066128.1 hypothetical protein -
CLC88_RS00285 () 68441..68620 - 180 WP_000970212.1 hypothetical protein -
CLC88_RS00290 () 68641..69633 - 993 WP_000817328.1 conjugal transfer pilus assembly protein TraU -
CLC88_RS00295 () 69630..70262 - 633 WP_001203739.1 type-F conjugative transfer system protein TraW -
CLC88_RS00300 () 70259..70645 - 387 WP_000214090.1 type-F conjugative transfer system protein TrbI -
CLC88_RS00305 () 70642..73271 - 2630 Protein_61 type IV secretion system protein TraC -
CLC88_RS00310 () 73395..73742 - 348 WP_052918901.1 hypothetical protein -
CLC88_RS00315 () 74068..74541 - 474 WP_000549599.1 hypothetical protein -
CLC88_RS00320 () 74552..74947 - 396 WP_000549593.1 hypothetical protein -
CLC88_RS00325 () 74940..75161 - 222 WP_001278977.1 conjugal transfer protein TraR -
CLC88_RS00330 () 75296..75809 - 514 Protein_66 type IV conjugative transfer system lipoprotein TraV -
CLC88_RS00335 () 75806..76056 - 251 Protein_67 conjugal transfer protein TrbG -
CLC88_RS00340 () 76170..76400 - 231 WP_155704887.1 conjugal transfer protein TrbD -
CLC88_RS00345 () 76354..76940 - 587 Protein_69 conjugal transfer protein TraP -
CLC88_RS00350 () 76930..78359 - 1430 Protein_70 conjugal transfer protein TraB -
CLC88_RS00355 () 78359..79087 - 729 WP_001365587.1 type-F conjugative transfer system secretin TraK -
CLC88_RS00360 () 79074..79640 - 567 WP_000399759.1 type IV conjugative transfer system protein TraE -
CLC88_RS00365 () 79662..79972 - 311 Protein_73 type IV conjugative transfer system protein TraL -
CLC88_RS00370 () 79987..80364 - 378 WP_155704889.1 type IV conjugative transfer system pilin TraA -
CLC88_RS00375 () 80391..80601 - 211 Protein_75 conjugal transfer relaxosome protein TraY -
CLC88_RS00380 () 81560..81931 - 372 Protein_76 relaxosome protein TraM -
CLC88_RS00385 () 82248..82850 + 603 WP_077698133.1 hypothetical protein VF
CLC88_RS25580 () 83146..83957 - 812 Protein_78 DUF945 domain-containing protein -
CLC88_RS25585 () 84071..84342 - 272 Protein_79 hypothetical protein -
CLC88_RS00400 () 84511..84812 - 302 Protein_80 hypothetical protein -
CLC88_RS25590 () 85105..85394 + 290 Protein_81 hypothetical protein -
CLC88_RS00410 () 85688..85849 - 162 WP_000775238.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 85907..86099 - 193 NuclAT_0 - Antitoxin Detail
- () 85907..86099 - 193 NuclAT_0 - Antitoxin Detail
- () 85907..86099 - 193 NuclAT_0 - Antitoxin Detail
- () 85907..86099 - 193 NuclAT_0 - Antitoxin Detail
CLC88_RS00415 () 86048..86361 - 314 Protein_83 theronine dehydrogenase -
CLC88_RS00420 () 86303..87068 - 766 Protein_84 plasmid SOS inhibition protein A -
CLC88_RS00425 () 87070..87496 - 427 Protein_85 conjugation system SOS inhibitor PsiB -
CLC88_RS00430 () 87551..89509 - 1959 WP_050864290.1 ParB/RepB/Spo0J family partition protein -
CLC88_RS00435 () 89573..89806 - 234 WP_000005988.1 DUF905 family protein -
CLC88_RS00440 () 89864..90384 - 521 Protein_88 single-stranded DNA-binding protein -
CLC88_RS00450 () 90727..91233 + 507 WP_148723668.1 hypothetical protein -
CLC88_RS00455 () 91214..91777 - 564 WP_050864291.1 class I SAM-dependent methyltransferase -
CLC88_RS00460 () 91823..93184 - 1362 WP_000175497.1 DUF3560 domain-containing protein -
CLC88_RS00465 () 93236..93465 - 230 Protein_92 hypothetical protein -
CLC88_RS25595 () 94141..94449 + 309 WP_071830340.1 pilus assembly protein -
CLC88_RS00475 () 94428..94619 - 192 WP_001027048.1 hypothetical protein -
CLC88_RS00480 () 94619..95038 - 420 WP_000271710.1 DUF1380 family protein -
CLC88_RS00485 () 95085..95387 - 303 WP_001364029.1 antirestriction protein -
CLC88_RS00495 () 95926..96697 - 772 Protein_97 hypothetical protein -
CLC88_RS00500 () 96747..97181 - 435 WP_000274460.1 DUF1380 family protein -
CLC88_RS00505 () 97195..97415 - 221 Protein_99 hypothetical protein -
CLC88_RS00510 () 97416..98068 - 653 Protein_100 DNA methylase -
CLC88_RS00515 () 98648..100347 + 1700 Protein_101 group II intron reverse transcriptase/maturase -
CLC88_RS00520 () 100591..100880 - 290 Protein_102 hypothetical protein -
CLC88_RS00525 () 100877..101775 - 899 Protein_103 DUF1281 domain-containing protein -
CLC88_RS00530 () 102194..102442 + 249 WP_000618108.1 DinI-like family protein -
CLC88_RS00535 () 102439..102876 + 438 WP_000109074.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CLC88_RS00540 () 102876..104146 + 1271 Protein_106 translesion error-prone DNA polymerase V subunit UmuC -
CLC88_RS00550 () 104151..104543 - 393 WP_000340836.1 plasmid partitioning/stability family protein -
CLC88_RS00555 () 104548..105519 - 972 WP_001103695.1 hypothetical protein -
CLC88_RS00560 () 105748..106392 + 645 WP_000633912.1 AAA family ATPase -
CLC88_RS00565 () 106386..106661 + 276 WP_000239527.1 hypothetical protein -
CLC88_RS00570 () 106799..107608 - 810 WP_000016958.1 site-specific integrase -
CLC88_RS00575 () 107609..107914 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
CLC88_RS00580 () 107916..108134 - 219 WP_000813639.1 type II toxin-antitoxin system antitoxin CcdA -
CLC88_RS00585 () 108730..108990 + 261 WP_000343084.1 hypothetical protein -
CLC88_RS00590 () 108987..109577 + 591 WP_000194564.1 hypothetical protein -
CLC88_RS00595 () 109595..109941 - 347 Protein_116 hypothetical protein -
CLC88_RS00600 () 110125..110403 + 279 WP_001365566.1 hypothetical protein -
CLC88_RS00605 () 110410..110745 - 336 Protein_118 colicin -
CLC88_RS00610 () 110840..111570 - 731 Protein_119 complement resistance protein TraT -
CLC88_RS25600 () 111847..111957 - 111 Protein_120 IS481 family transposase -
CLC88_RS00615 () 112741..113718 + 978 WP_050864229.1 RepB family plasmid replication initiator protein -
CLC88_RS00620 () 113957..114239 - 283 Protein_122 ISL3 family transposase ISEc53 Transposase
CLC88_RS00625 () 114396..114626 - 231 WP_032279745.1 hypothetical protein -
CLC88_RS00630 () 114756..115250 - 495 WP_050864230.1 Transcriptional repressor MprA VF
CLC88_RS00635 () 115371..116810 - 1440 WP_021293303.1 Hemolysin secretion protein D, chromosomal VF
CLC88_RS00640 () 116814..118934 - 2121 WP_072094473.1 Alpha-hemolysin translocation ATP-binding protein HlyB VF
CLC88_RS00645 () 118984..121980 - 2997 WP_000217728.1 Hemolysin, chromosomal VF
CLC88_RS00650 () 121982..122496 - 515 Protein_128 RTX-I toxin-activating lysine-acyltransferase ApxIC VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance