MGE detailed information
MGE type: Conjugative plasmid MGE length: 139450 bp
Accession: NZ_AP022327 Location: 1..139450 Organism: Escherichia coli O25:H4 strain 18044 Replicon: plasmid p18044_1
Accession: NZ_AP022327 Location: 1..139450 Organism: Escherichia coli O25:H4 strain 18044 Replicon: plasmid p18044_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECO25NV_RS24505 () | 101..1078 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| ECO25NV_RS24510 () | 1363..2103 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| ECO25NV_RS24515 () | 2224..2412 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| ECO25NV_RS24520 () | 2779..3948 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| ECO25NV_RS24525 () | 4174..4349 | - | 176 | Protein_4 | IS3 family transposase | - |
| ECO25NV_RS24530 () | 4795..5067 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| ECO25NV_RS24535 () | 5592..6028 | - | 437 | Protein_6 | transposase | - |
| ECO25NV_RS24540 () | 6310..8280 | + | 1971 | WP_001298664.1 | TonB-dependent hemoglobin/transferrin/lactoferrin family receptor | - |
| ECO25NV_RS24545 () | 8287..9078 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| ECO25NV_RS24550 () | 9141..9749 | - | 609 | Protein_9 | IS66 family transposase | - |
| ECO25NV_RS24555 () | 9817..10599 | - | 783 | WP_001300609.1 | IS21-like element IS100kyp family helper ATPase IstB | - |
| ECO25NV_RS24560 () | 10596..11618 | - | 1023 | WP_001310017.1 | IS21-like element IS100 family transposase | - |
| ECO25NV_RS24565 () | 11704..12649 | - | 946 | Protein_12 | IS66 family transposase | - |
| ECO25NV_RS24570 () | 12698..13045 | - | 348 | WP_000612626.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| ECO25NV_RS24575 () | 13042..13446 | - | 405 | WP_000839179.1 | IS66 family insertion sequence hypothetical protein | - |
| ECO25NV_RS24580 () | 13475..13837 | - | 363 | Protein_15 | DDE-type integrase/transposase/recombinase | - |
| ECO25NV_RS24585 () | 13947..15455 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| ECO25NV_RS24590 () | 16128..16867 | - | 740 | Protein_17 | IS3 family transposase | - |
| ECO25NV_RS24595 () | 16893..17198 | + | 306 | Protein_18 | IS91 family transposase | - |
| ECO25NV_RS24600 () | 17721..18896 | - | 1176 | WP_001020413.1 | enterotoxin production-related protein TieB | - |
| ECO25NV_RS24605 () | 18965..21226 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| ECO25NV_RS24610 () | 21395..22171 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| ECO25NV_RS24615 () | 22179..23054 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| ECO25NV_RS24620 () | 23386..23933 | - | 548 | Protein_23 | replication initiation protein | - |
| ECO25NV_RS24625 () | 25505..25840 | - | 336 | WP_001080732.1 | colicin transporter | - |
| ECO25NV_RS24630 () | 25969..26316 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| ECO25NV_RS24635 () | 26336..26845 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| ECO25NV_RS24640 () | 26842..27102 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| ECO25NV_RS24645 () | 27204..27943 | + | 740 | Protein_28 | IS3 family transposase | - |
| ECO25NV_RS24650 () | 28616..28930 | + | 315 | Protein_29 | hypothetical protein | - |
| ECO25NV_RS24655 () | 28931..29104 | + | 174 | Protein_30 | transposase | - |
| ECO25NV_RS24660 () | 29254..29887 | - | 634 | Protein_31 | histidine-type phosphatase | - |
| ECO25NV_RS24665 () | 30009..30494 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| ECO25NV_RS24670 () | 30519..31004 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| ECO25NV_RS24675 () | 30991..31686 | - | 696 | WP_000117262.1 | ABC transporter ATP-binding protein | - |
| ECO25NV_RS24680 () | 31691..32821 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| ECO25NV_RS24685 () | 32811..34094 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| ECO25NV_RS24690 () | 34097..35476 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| ECO25NV_RS24695 () | 35580..36107 | - | 528 | WP_000178050.1 | iron transporter | - |
| ECO25NV_RS24700 () | 36148..38034 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| ECO25NV_RS24705 () | 38381..39196 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| ECO25NV_RS24710 () | 39379..39885 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| ECO25NV_RS24715 () | 39875..40033 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| ECO25NV_RS24720 () | 40183..40296 | - | 114 | Protein_43 | IS6 family transposase | - |
| ECO25NV_RS24725 () | 40496..41169 | + | 674 | Protein_44 | IS1 family transposase | - |
| ECO25NV_RS24730 () | 41222..41926 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| ECO25NV_RS24735 () | 41985..42734 | - | 750 | Protein_46 | class 1 integron integrase IntI1 | - |
| ECO25NV_RS24740 () | 42892..43365 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| ECO25NV_RS24745 () | 43496..44284 | + | 789 | WP_000503573.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5 | - |
| ECO25NV_RS24750 () | 44490..44837 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| ECO25NV_RS24755 () | 44831..45670 | + | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| ECO25NV_RS24760 () | 45798..46001 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| ECO25NV_RS24765 () | 46157..47362 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| ECO25NV_RS24770 () | 47373..47678 | + | 306 | WP_000130000.1 | PadR family transcriptional regulator | - |
| ECO25NV_RS24775 () | 47722..47787 | + | 66 | Protein_54 | EAL domain-containing protein | - |
| ECO25NV_RS24780 () | 47905..48669 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| ECO25NV_RS24785 () | 49162..49746 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| ECO25NV_RS24790 () | 49746..50984 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| ECO25NV_RS24795 () | 50981..51886 | - | 906 | WP_000219391.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| ECO25NV_RS24800 () | 52008..52712 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| ECO25NV_RS24805 () | 52773..52949 | + | 177 | Protein_60 | replication protein C | - |
| ECO25NV_RS24810 () | 53257..54072 | + | 816 | WP_001043260.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| ECO25NV_RS24815 () | 54133..54936 | + | 804 | WP_001082319.1 | aminoglycoside O-phosphotransferase APH(3'')-Ib | - |
| ECO25NV_RS24820 () | 54936..55772 | + | 837 | WP_000480972.1 | aminoglycoside O-phosphotransferase APH(6)-Id | - |
| ECO25NV_RS24825 () | 55826..56062 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| ECO25NV_RS24830 () | 56094..56720 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| ECO25NV_RS24835 () | 56826..58025 | + | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| ECO25NV_RS24840 () | 58057..58917 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| ECO25NV_RS24845 () | 58926..59264 | - | 339 | Protein_68 | transposase | - |
| ECO25NV_RS24850 () | 59319..60023 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| ECO25NV_RS24855 () | 60322..61182 | + | 861 | WP_000027057.1 | class A broad-spectrum beta-lactamase TEM-1 | - |
| ECO25NV_RS24860 () | 61332..61430 | - | 99 | Protein_71 | IS1 family transposase | - |
| ECO25NV_RS24865 () | 61459..62769 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| ECO25NV_RS24870 () | 63054..63455 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ECO25NV_RS24875 () | 63388..63645 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ECO25NV_RS24880 () | 63738..64391 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| ECO25NV_RS24885 () | 65331..66188 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| ECO25NV_RS24890 () | 66181..66255 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| ECO25NV_RS24895 () | 66252..66386 | - | 135 | Protein_78 | protein CopA/IncA | - |
| ECO25NV_RS24900 () | 66492..66746 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| ECO25NV_RS24905 () | 67043..67177 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 67222..67282 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 67222..67282 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 67222..67282 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 67222..67282 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| ECO25NV_RS24910 () | 67249..67535 | - | 287 | Protein_81 | DUF2726 domain-containing protein | - |
| ECO25NV_RS24915 () | 67613..69226 | - | 1614 | WP_000080195.1 | IS66-like element ISEc23 family transposase | - |
| ECO25NV_RS24920 () | 69257..69607 | - | 351 | WP_000624722.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| ECO25NV_RS24925 () | 69604..70029 | - | 426 | WP_000422741.1 | IS66 family insertion sequence hypothetical protein | - |
| ECO25NV_RS24930 () | 70588..70800 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| ECO25NV_RS24935 () | 70931..71491 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| ECO25NV_RS24940 () | 71546..72292 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| ECO25NV_RS24945 () | 72312..77582 | - | 5271 | WP_001617867.1 | conjugative transfer relaxase/helicase TraI | - |
| ECO25NV_RS24950 () | 77582..79780 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECO25NV_RS24955 () | 79777..80556 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| ECO25NV_RS24960 () | 80759..81490 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| ECO25NV_RS24965 () | 81522..82019 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| ECO25NV_RS24970 () | 82038..83483 | - | 1446 | Protein_93 | conjugal transfer protein TraG | - |
| ECO25NV_RS24975 () | 83549..84253 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| ECO25NV_RS24980 () | 84308..85621 | - | 1314 | Protein_95 | conjugal transfer mating pair stabilization protein TraG | - |
| ECO25NV_RS24985 () | 85618..86991 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| ECO25NV_RS24990 () | 86978..87403 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| ECO25NV_RS24995 () | 87351..87698 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| ECO25NV_RS25000 () | 87628..88173 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECO25NV_RS25005 () | 88160..88444 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECO25NV_RS25010 () | 88571..88891 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| ECO25NV_RS25015 () | 88939..89636 | - | 698 | Protein_102 | IS1 family transposase | - |
| ECO25NV_RS25020 () | 89687..90256 | - | 570 | WP_199805750.1 | conjugal transfer protein TraP | - |
| ECO25NV_RS25025 () | 90225..91676 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| ECO25NV_RS25030 () | 91676..92380 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| ECO25NV_RS25035 () | 92391..92957 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| ECO25NV_RS25040 () | 92979..93290 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| ECO25NV_RS25045 () | 93295..93657 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| ECO25NV_RS25050 () | 93691..93918 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| ECO25NV_RS25055 () | 94006..94683 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| ECO25NV_RS25060 () | 94817..95200 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| ECO25NV_RS25065 () | 95531..96133 | + | 603 | WP_000243712.1 | transglycosylase SLT domain-containing protein | - |
| ECO25NV_RS25070 () | 96430..97251 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| ECO25NV_RS25075 () | 97370..97657 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| ECO25NV_RS25080 () | 97682..97888 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| ECO25NV_RS25085 () | 98084..98734 | + | 651 | WP_001487415.1 | IS66 family insertion sequence hypothetical protein | - |
| ECO25NV_RS25090 () | 98734..99081 | + | 348 | WP_000624618.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| ECO25NV_RS25095 () | 99101..100672 | + | 1572 | WP_199805184.1 | IS66 family transposase | - |
| ECO25NV_RS25100 () | 101291..101449 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 101493..101533 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 101493..101533 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 101493..101533 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 101493..101533 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 102977..103163 | - | 187 | NuclAT_0 | - | - |
| - () | 102977..103163 | - | 187 | NuclAT_0 | - | - |
| - () | 102977..103163 | - | 187 | NuclAT_0 | - | - |
| - () | 102977..103163 | - | 187 | NuclAT_0 | - | - |
| ECO25NV_RS25110 () | 103175..103894 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| ECO25NV_RS25115 () | 103891..104325 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| ECO25NV_RS25120 () | 104380..106338 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| ECO25NV_RS25125 () | 106404..106637 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| ECO25NV_RS25130 () | 106700..107239 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| ECO25NV_RS25135 () | 107384..107719 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| ECO25NV_RS25140 () | 107882..108142 | - | 261 | WP_024623314.1 | hypothetical protein | - |
| ECO25NV_RS25145 () | 108168..108731 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| ECO25NV_RS25150 () | 108779..110140 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| ECO25NV_RS25155 () | 110192..110422 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| ECO25NV_RS25160 () | 111457..111648 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| ECO25NV_RS25165 () | 111645..112067 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| ECO25NV_RS25170 () | 112114..112416 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| ECO25NV_RS25175 () | 112956..113732 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| ECO25NV_RS25180 () | 113783..114217 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| ECO25NV_RS25185 () | 114231..114452 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| ECO25NV_RS25190 () | 114453..115136 | - | 684 | WP_000086185.1 | DNA methylase | - |
| ECO25NV_RS25195 () | 115213..115517 | - | 305 | Protein_138 | hypothetical protein | - |
| ECO25NV_RS25200 () | 115521..116423 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| ECO25NV_RS25205 () | 117290..118261 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ECO25NV_RS25210 () | 118261..119427 | - | 1167 | WP_000772446.1 | plasmid-partitioning protein SopA | - |
| ECO25NV_RS25215 () | 120015..120770 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| ECO25NV_RS25220 () | 121544..122350 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| ECO25NV_RS25225 () | 122351..122656 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| ECO25NV_RS25230 () | 122658..122876 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| ECO25NV_RS25235 () | 123584..124579 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| ECO25NV_RS25240 () | 124583..125515 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| ECO25NV_RS25245 () | 125652..126349 | - | 698 | Protein_148 | IS1 family transposase | - |
| ECO25NV_RS25250 () | 126405..127529 | - | 1125 | Protein_149 | HsdR family type I site-specific deoxyribonuclease | - |
| ECO25NV_RS25255 () | 127651..128922 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| ECO25NV_RS25260 () | 128919..130475 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| ECO25NV_RS25265 () | 130658..130879 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| ECO25NV_RS25270 () | 130879..131259 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| ECO25NV_RS25275 () | 131264..131443 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| ECO25NV_RS25280 () | 131471..131830 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| ECO25NV_RS25285 () | 131754..132167 | + | 414 | Protein_156 | DDE-type integrase/transposase/recombinase | - |
| ECO25NV_RS25290 () | 132117..132434 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| ECO25NV_RS25295 () | 132662..133678 | - | 1017 | WP_012372828.1 | IS5-like element IS5 family transposase | - |
| ECO25NV_RS25300 () | 133886..135289 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| ECO25NV_RS25305 () | 135276..136208 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| ECO25NV_RS25310 () | 136317..136646 | - | 330 | Protein_161 | TOBE domain-containing protein | - |
| ECO25NV_RS25315 () | 136662..137359 | - | 698 | Protein_162 | IS1 family transposase | - |
| ECO25NV_RS25320 () | 137417..137665 | + | 249 | Protein_163 | abortive infection family protein | - |
| ECO25NV_RS25325 () | 138034..138765 | - | 732 | WP_001617898.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|