Francisellaceae


experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0147 experimental FTT1557c/FNU0663.2 (pmrA) T6SS00081 experimental protein TCS-RR Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 1618742..1619428 (-) 489108239 T6SS transcription (↓)
REG0173 experimental FTN_RS06610 (mglA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1362282..1362899 (+) 489124662 iglC transcription (↓); Unknown (↓)
REG0174 experimental FTN_RS02845 (SspA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 574840..575472 (+) 500053699 FTN_1465 (pmrA) (↓)
REG0175 experimental FTN_RS08805 (KdpD) T6SS00158 experimental protein TCS-HK Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1838601..1841282 (-) 489131611 FTN_1465 (pmrA) (↓)
REG0176 experimental FTN_1465 (pmrA) T6SS00158 experimental protein TCS-RR; TCS regulatory pathway Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1553358..1554044 (-) 489108239 FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimental FTN_RS06615 (mglB) T6SS00158 experimental protein Global regulator; TCS regulatory pathway Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1362901..1363308 (+) 489112095 IglA expression (↓); T6SS Transciption (↓)
REG0178 experimental FTN_0480 (fevR/PigR) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 486541..486876 (+) 489108070 T6SS Transciption (↓)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Effector ID Locus tag (Gene) Classification Cognate immunity protein Related T6SS Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
EFF01494 experimental FTN_1319 (pdpC) Tle - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1391204..1395181 (+) 118497899
EFF01487 experimental FTN_0131 (opiA) Tse - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 143587..144894 (-) 118496746
EFF01489 experimental FTN_1325 (pdpD) Tse - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1399803..1403540 (-) 118497905
EFF01491 experimental FTN_1069 (OpiB-1) Tse - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1128155..1130653 (-) 118497660
EFF01492 experimental FTN_1070 (OpiB-2) Tse - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1130861..1132213 (-) 118497661
EFF01493 experimental FTN_1071 (OpiB-3) Tse - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1132421..1133899 (-) 118497662
EFF00108 experimental FTT_1347 (VgrG) - - T6SS00080 experimental Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 1779388..1779882 (+) 56708711
EFF00109 experimental FTL_0118 (IglI) - - T6SS00080 experimental Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 1784240..1785391 (+) 56708716
EFF00110 experimental FTT_1347 (VgrG) - - T6SS00081 experimental Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 1386053..1386547 (+) 56708403
EFF00111 experimental FTL_0118 (IglI) - - T6SS00081 experimental Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 1390905..1392056 (+) 56708408
EFF00204 experimental FTN_1317 (IglI) - - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1389274..1390425 (+) 118497897
EFF00203 experimental FTN_1312 (VgrG) - - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1384422..1384916 (+) 118497892
EFF01488 experimental FTN_1309 (pdpA) - - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1378294..1380756 (+) 118497889
EFF01490 experimental FTN_1322 (iglC) - - T6SS00158 experimental Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1396989..1397618 (-) 118497902
EFF00563 experimental FTT_1347 (VgrG) - - T6SS00466 experimental Francisella tularensis subsp. holarctica LVS chromosome (NC_007880) 117678..118172 (-) 89255560
EFF00562 experimental FTL_0118 (IglI) - - T6SS00466 experimental Francisella tularensis subsp. holarctica LVS chromosome (NC_007880) 112168..113319 (-) 89255555
EFF00565 experimental FTT_1347 (VgrG) - - T6SS00467 experimental Francisella tularensis subsp. holarctica LVS chromosome (NC_007880) 1112317..1112811 (-) 89256491
EFF00564 experimental FTL_0118 (IglI) - - T6SS00467 experimental Francisella tularensis subsp. holarctica LVS chromosome (NC_007880) 1106807..1107958 (-) 89256486

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Immunity protein ID Locus tag (Gene) Related T6SS Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Cognate effector

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
ID           Locus tag (Gene) Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Response to T6SS attack Known or putative function

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Accessory protein ID Locus tag (Gene) Related T6SS Type             Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Related structure protein Related effector
ACP00019 experimental FTT_0682c (fipB/dsbA) T6SS00080 experimental structure affiliated protein Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 699171..700016 (-) 56707802 FTT_1713c (IglB2); FTT_1712c (IglC2) -
ACP00020 experimental FTT_0682c (fipB/dsbA) T6SS00081 experimental chaperone Francisella tularensis subsp. tularensis SCHU S4 chromosome (NC_006570) 699171..700016 (-) 56707802 FTT_1358c (IglB1); FTT_1357c (IglC1) -
ACP00023 experimental FTN_RS06580 (dnaK) T6SS00158 experimental chaperone Francisella tularensis subsp. novicida U112 chromosome (NC_008601) 1356202..1358130 (-) 489130276 FTN_RS08950 (ClpB) -