Regulator List



Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0001 experimental vfu_A02134 (ihfA) T6SS00529 insolico; T6SS00530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 chromosome (NC_016602) 2226951..2227244 (-) 490864172 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0002 experimental vfu_A02422 (ihfB) T6SS00529 insolico; T6SS00530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 chromosome (NC_016602) 2516092..2516376 (-) 490864456 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0003 experimental RT90_01105 (rcsC) T6SS01264 experimental protein TCS-HK Serratia marcescens strain RM66262 chromosome (JWLO01000001) 232638..235499 (+) 735006326 RT90_01115 (rcsB) (↑)
REG0004 experimental RT90_01115 (rcsB) T6SS01264 experimental protein TCS-RR Serratia marcescens strain RM66262 chromosome (JWLO01000001) 235561..236211 (-) 735006328 vgrG promoter (↓)
REG0005 experimental RT90_16255 (wecG) T6SS01264 experimental protein TCS regulatory pathway Serratia marcescens strain RM66262 chromosome (JWLO01000003) 92056..92796 (-) 735005313 RT90_01105 (rcsC) (↑)
REG0006 experimental L085_RS13655 (ppka) T6SS01033 experimental protein Tpp Serratia sp FS14 chromosome (NZ_CP005927) 3028273..3029718 (-) 763151328 Unknown (↓)
REG0007 experimental PA4740/Y880_04683 (pnp) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0010 experimental Y880_06257 (rsmA) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental Y880_05180 (rmsF) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0012 experimental Y880_02189 (gacA/uvrY) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein TCS-RR Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 2199690..2200334 (-) 510933056 hcp expression (↓)
REG0013 experimental Y880_03649 (suhB) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein TCS regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 3616623..3617438 (+) 489183406 Y880_02189 (gacA/uvrY) (↓)
REG0014 experimental SMDB11_2275 (PpKA) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2399154..2400599 (+) 560174118 SMDB11_2267 (FHA) (↓)
REG0015 experimental SMDB11_2268 (PppA) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2390232..2391005 (+) 560174111 SMDB11_2267 (FHA) (↑)
REG0016 experimental SMDB11_2269 (RtkS) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2391034..2392020 (+) 560174112 SMDB11_2275 (PpKA) (↓)
REG0017 experimental SMDB11_2256 (TagF) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2380702..2381421 (+) 560174099 Unknown (↑)
REG0018 experimental PA4462 (RpoN) T6SS00003 experimental; T6SS00004 experimental; T6SS00005 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 PA1512 (hcpA) promotor (↓); PA5267 (hcpB) promotor (↓)
REG0019 experimental PC1_3721 (Hfq) T6SS01001 insolico protein QS regulatory pathway Pectobacterium carotovorum subsp carotovorum PC1 chromosome (CP001657) 4199890..4200189 (-) 251756660 hcp expression (↓)
REG0021 experimental GPY04_RS11195 (CytR) T6SS01168 experimental protein Unknown Vibrio cholerae C6706 chromosome (NZ_CP046844) 2449479..2450486 (-) 446146597 Unknown (↓)
REG0022 experimental GPY04_RS03590 (TfoX) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 777344..777952 (+) 487807468 Unknown (↓)
REG0023 experimental GPY04_RS00870 (HapR) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 164935..165546 (-) 446262243 Unknown (↓)
REG0024 experimental GPY04_RS13335/VC0070 (tsrA) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2888303..2888587 (+) 445982516 T6SS transcripts (↑)
REG0029 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046845) 273631..274983 (-) 446367907 VC0070 (tsrA) (↑)
REG0030 experimental GPY04_RS13825 (QstR) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2994333..2994977 (-) 447111060 Unknown (↓)
REG0031 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2994333..2994977 (-) 447111060 Unknown (↓)
REG0032 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046845) 273631..274983 (-) 446367907 GPY04_RS00870 (hapR) (↑)
REG0033 experimental GPY04_RS01040 (ChiS) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 210606..213995 (-) 446410424 Necessory for TfoX/TfoR (↓)
REG0034 experimental GPY04_RS03200 (chiA2) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 692014..695280 (+) 487807405 GPY04_RS01040 (ChiS) (↓)
REG0035 experimental GPY04_RS07700 (chiA1) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 1709613..1712153 (-) 446755770 GPY04_RS01040 (ChiS) (↓)
REG0036 experimental VC1920/VCA1552_01695 (LonA) T6SS01112 experimental protein Unknown Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1845472..1847832 (-) 446970355 Unknown (↑)
REG0037 experimental Y880_05519 (dgcP) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein c-di-GMP regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5487251..5489266 (-) 489205065 the levels of c-di-GMP (↓)
REG0038 experimental PSA3335_06200 (dgcP) T6SS01041 insolico protein c-di-GMP regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 chromosome (NZ_CP008742) 1344347..1346692 (+) 488618048 the levels of c-di-GMP (↓)
REG0039 experimental VC_RS13930 (VasH) T6SS00002 experimental protein Global regulator Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 128790..130382 (+) 446006938 VCA0017 (hcp-2) transcript (↓)
REG0040 experimental PA0592 (RsmA) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental PA5183a (RsmN) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0042 experimental PA0075 (PppA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90106..90834 (-) 15595273 PA0081 (Fha-1/TagH) (↑)
REG0043 experimental PA0074 (PpkA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 87000..90098 (-) 15595272 PA0081 (Fha-1/TagH) (↓)
REG0044 experimental PA2586 (gacA) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2925788..2926432 (-) 15597782 hcp1 (PA0085) expression and secretion (↓)
REG0045 experimental PA0610 (prtN) T6SS00003 experimental protein TCS-HK Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 672777..673091 (-) 15595807 PA0611 (prtR) (↑)
REG0046 experimental PA0611 (prtR) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 673191..673961 (-) 15595808 hcp1 (PA0085) expression and secretion (↑); PA2586 (gacA) (↑)
REG0047 experimental PA0072 (TagS) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 85085..86284 (-) 15595270 PA0073 (TagT) (↓)
REG0048 experimental PA0070 (TagQ) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 82404..83318 (-) 15595268 PA0071 (tagR) (↓)
REG0049 experimental PA0073 (TagT) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 86284..87003 (-) 15595271 PA0072 (TagS) (↓)
REG0050 experimental PA2492 (MexT) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental PA1006 T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0052 experimental PA0071 (tagR) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 83380..85092 (-) 15595269 PA0074 (PpkA) (↓)
REG0053 experimental PA4856 (RetS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5452150..5454978 (+) 15600049 hcp1 (PA0085) expression and secretion (↑)
REG0054 experimental PA3974 (LadS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4453289..4455676 (-) 15599169 hcp1 (PA0085) expression and secretion (↓)
REG0055 experimental PA4109 (AmpR) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0056 experimental PA0076 (TagF) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90844..91524 (-) 15595274 hcp1 (PA0086) secretion (↑)
REG0057 experimental PA0081 (Fha-1/TagH) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 98263..99756 (-) 15595279 Unknown (↓); clpV (↓)
REG0058 experimental PA2976 (RNase E) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0061 experimental PA0996 (pqsA) T6SS00004 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1078462..1080015 (+) 15596193 T6SS transcripts
REG0062 experimental PA1244 (QslA) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1348060..1348401 (-) 15596441 H2-T6SS (PA1656) promotor (↑)
REG0063 experimental PA4778 (CueR) T6SS00004 experimental protein Transcription regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5366257..5366655 (+) 15599972 tssA2 (-173 to -140 relative to the ATG start codon) (↓); hcp2 (-208 to -159 relative to the ATG start codon) (↓)
REG0064 experimental PA4856 (RetS) T6SS00004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5366257..5366655 (+) 15599972 H2-T6SS (↑)
REG0065 experimental PA1430 (LasR) T6SS00004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1558171..1558890 (+) 15596627 H2-T6SS promotor P (hsiA2) (↓)
REG0066 experimental PA3476 (rhlI) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889139..3889744 (-) 15598672 PA3477 (RhlR) (↓)
REG0067 experimental PA3477 (RhlR) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889925..3890650 (-) 15598673 T6SS transcript (↓)
REG0068 experimental PA4764 (Fur) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5351675..5352079 (-) 15599958 H2-T6SS Transcription (↑)
REG0069 experimental PA4462 (rpoN) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 T6SS transcript (↑)
REG0070 experimental pa1663 (sfa2) T6SS00004 experimental; T6SS00005 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1813395..1814906 (+) 15596860 PA4462 (rpoN) (↑); T6SS transcript (↑); T6SS transcript (↓)
REG0071 experimental Z4049 (RpoS) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 3654380..3655372 (-) 446003635 Z1921 (KatN) (↓)
REG0072 experimental Z5519 (OxyR) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 5033893..5034810 (+) 446948683 Z1921 (KatN) (↓)
REG0073 experimental Z2013 (hns) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 1829490..1829903 (-) 447210122 Z0264 (hcp-2) (↑)
REG0074 experimental PP_4373 (FleQ) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 4963882..4965357 (-) 26991062 K1-T6SS (hcp1) expression (↑)
REG0075 experimental PP_0952 (RopN) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 1094567..1096060 (-) 26987688 PP_4373 (FleQ) (↑)
REG0076 experimental PP_0914 (BifA) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 1055990..1058071 (-) 26987650 the levels of c-di-GMP (↓)
REG0077 experimental Atu4335 (Fha/TagH) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1467064..1468263 (-) 499280697 Unknown (↓)
REG0078 experimental Atu4330 (PpkA) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1458366..1459271 (-) 737274050 Unknown (↓)
REG0079 experimental Atu4331 (TagF-PppA) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1459258..1460673 (-) 159186120 Fha (Atu4335) (↑)
REG0080 experimental Atu2091 T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003063) 2054055..2054864 (-) 159185045 the levels of c-di-GMP (↑)
REG0081 experimental Atu5372 T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003064) 363293..364387 (+) 1805892863 the levels of c-di-GMP (↑)
REG0082 experimental Atu1257 (DgcA) T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 1244567..1245814 (-) 159184686 the levels of c-di-GMP (↑)
REG0083 experimental Atu2179 (DgcC) T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 2154605..2155744 (-) 159185090 the levels of c-di-GMP (↑)
REG0084 experimental chvG T6SS00016 experimental protein TCS-HK Agrobacterium fabrum str C58 chromosome (NC_003062) 34679..36469 (-) chvI (↓)
REG0085 experimental chvI T6SS00016 experimental protein TCS-RR Agrobacterium fabrum str C58 chromosome (NC_003062) 36525..37250 (-) The intergenic region of the imp and hcp operons (↓)
REG0086 experimental exoR T6SS00016 experimental protein TCS regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 1702398..1703192 (-) chvG (↑)
REG0087 experimental STM1751 (H-NS) T6SS00023 experimental protein Global regulator Salmonella enterica subsp enterica serovar Typhimurium str LT2 chromosome (NC_003197) 1847277..1847690 (+) 16765095 STM0272 (ClpV) promotor (↑); STM0279 (hcp) promotor (↑); STM0285 promotor (↑); STM0289 (VgrG) promotor (↑); STM0268 promotor (↑)
REG0088 experimental STM0693 (Fur) T6SS00023 experimental protein Global regulator Salmonella enterica subsp enterica serovar Typhimurium str LT2 chromosome (NC_003197) 756397..756849 (-) 16764063 STM0272 (ClpV) promoter (↑)
REG0089 experimental xac4129 (ecfK/RpoE,ECF σ factor) T6SS00028 insolico protein Unknown Xanthomonas citri pv citri str 306 chromosome (NC_003919) 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental xac4127 (PknS) T6SS00028 insolico protein Unknown Xanthomonas citri pv citri str 306 chromosome (NC_003919) 4846892..4849411 (-) 505284326 Unknown (↓)
REG0091 experimental PFL_RS17995 (gacA/uvrY/SirA) T6SS00035 experimental protein TCS-RR Pseudomonas protegens Pf-5 chromosome (NC_004129) 4110513..4111154 (-) 499374263 T6SS transcripts (↓)
REG0092 experimental PFL_RS30815 (pppA) T6SS00035 experimental protein Tpp Pseudomonas protegens Pf-5 chromosome (NC_004129) 6902924..6903658 (-) 499376669 Hcp secretion (↑)
REG0093 experimental ECA_RS00520 (expI) T6SS00040 experimental protein QS regulatory pathway Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 125689..126339 (+) 499404281 T6SS transcripts (ECA4275[hcp1], ECA3428[hcp2] and ECA2866[hcp3]) (↓)
REG0094 experimental ECA3435 (bEBP/VasH) T6SS00040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 3850745..3852298 (-) 499407476 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0095 experimental ECA0288 (rpoN) T6SS00040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 336007..337440 (-) 499404454 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0096 experimental PSPTO_RS08845 (relA) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 1863879..1866122 (+) 494457621 T6SS transcripts (↓)
REG0097 experimental PSPTO_RS00410 (spoT) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 94805..96910 (-) 492171753 T6SS transcripts (↓)
REG0098 experimental PSPTO_RS04545 (fpRel) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 927082..927900 (+) 499415849 T6SS transcripts (↓)
REG0099 experimental PSPTO_RS28060 (Sfa) T6SS00041 insolico; T6SS00042 experimental protein Global regulator Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 6165047..6166564 (-) 499418021 T6SS transcripts (↓)
REG0100 experimental VP_RS12495 (barA) T6SS00043 experimental; T6SS00044 experimental protein TCS-HK Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2712492..2715290 (+) 491625032 Hcp expression and secretion (↓)
REG0101 experimental VP_RS09470 (UvrY) T6SS00043 experimental; T6SS00044 experimental protein TCS-RR Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2037468..2038112 (-) 491529158 CsrB (↓)
REG0102 experimental VP_RS12395 (CsrA) T6SS00043 experimental; T6SS00044 experimental protein carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2688313..2688510 (-) 490550575 Hcp and vgrG expression and secretion (↓)
REG0106 experimental vp2049 (Thymidylate kinase,Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0107 experimental VP1028 (TfoY) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1077946..1078536 (-) 28897802 T6SS1 (VgrG1) expression and secretion (↓)
REG0108 experimental vp1391 T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1491226..1492857 (-) 28898165 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental vp1407 T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0110 experimental VP1133 (hns) T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1189718..1190125 (-) 28897907 VP1028 (TfoY) (↑)
REG0111 experimental VP2762 (AphA) T6SS00043 experimental; T6SS00044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2929909..2930448 (+) 28899536 T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112 experimental VP2516 (opaR) T6SS00043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2653215..2653829 (+) 28899290 vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑)
REG0114 experimental VP0820 (ToxR) T6SS00043 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 847892..848770 (-) 28897594 VP1400 promotor (↑); VP1409 promotor (↑)
REG0115 experimental VP0350 (CalR/LeuO) T6SS00044 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 344763..345722 (+) 28897124 VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0116 experimental VPA1088 (cdpA) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004605) 1147728..1150091 (+) 28900943 VP1028 (TfoY) (↑)
REG0117 experimental VPA0739 (vdcA) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004605) 772439..773809 (+) 28900594 VP1028 (TfoY) (↓)
REG0118 experimental VP2516 (OpaR) T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2653215..2653829 (+) 28899290 T6SS1 (↓)
REG0119 experimental VP1241 (TfoX) T6SS00044 experimental; T6SS00043 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1309223..1309810 (+) 28898016 T6SS2 (↓); T6SS1 (↓)
REG0120 experimental CV_RS20220 (CviR) T6SS00049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 chromosome (NC_005085) 4426186..4427046 (+) 1169634970 CV_RS06990 (VgrG) promotor (↓)
REG0121 experimental CV_RS23145 (CviI) T6SS00049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 chromosome (NC_005085) 4426967..4427620 (-) 499450174 CV_RS20220 (CviR) (↓)
REG0122 experimental VF2177 (LitR) T6SS00084 experimental protein QS regulatory pathway Aliivibrio fischeri ES114 chromosome (NC_006840) 2446537..2447142 (+) 59712784 Unknown (↓)
REG0123 experimental VF0896 (TfoX) T6SS00084 experimental protein Global regulator Aliivibrio fischeri ES114 chromosome (NC_006840) 986000..986629 (+) 59711503 T6SS transcripts (↓)
REG0124 experimental VFFQA001_02105 (rpoN) T6SS01277 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 chromosome (NZ_SJSX01000002) 62995..64464 (-) 501526930 hcp1/hcp transcript (↓)
REG0125 experimental VFFQA001_15620 (VasH) T6SS01278 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 chromosome (NZ_SJSX01000004) 359608..360108 (+) 1027725198 Unknown (↓)
REG0126 experimental BMAA1517 T6SS00070 experimental protein Transcription regulator Burkholderia mallei ATCC 23344 chromosome (NC_006349) 1646532..1647593 (-) 499517952 Hcp1 (BMAA0742) expression (↓)
REG0127 experimental BMAA0746 (VirG) T6SS00070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 chromosome (NC_006349) 764773..765510 (+) 490311617 Hcp1 (BMAA0742) expression (↓)
REG0128 experimental BMAA0745 (VirA) T6SS00070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 chromosome (NC_006349) 762932..764776 (+) 490305845 Hcp1 (BMAA0742) expression (↓)
REG0129 experimental BMAA0746 (VirG) T6SS00070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 chromosome (NC_006349) 764773..765510 (+) 53717366 BMAA0742 (Hcp1) expression (↓); BMAA0729.1 (TssM1) expression (↓)
REG0130 experimental BMAA0745 (VirA) T6SS00070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 chromosome (NC_006349) 763148..764776 (+) 53717365 BMAA0746 (VirG) (↓)
REG0131 experimental BPSL3431 (TctR) T6SS00074 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental BPSL2246 (PpiB) T6SS00076 insolico; T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental BPSS1504 T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006351) 2052905..2055547 (+) 499518990 hcp1 secretion
REG0134 experimental BPSS1546 (BsaN) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2100565..2101230 (-) 490660320 BPSS1495 (virA) promotor (↓)
REG0135 experimental BPS_RS27070 (bicA) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2087441..2087956 (-) 490293043 BPSS 1495(virA) (↓)
REG0136 experimental BPS_RS27175 (bprP) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2105881..2106081 (+) 490293055 BPSS1546 (BsaN) (↓)
REG0137 experimental BPSS1495 (virA) T6SS00077 insolico protein TCS-RR; BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2038711..2040555 (-) 499518988 T6SS-1 transpript (↓)
REG0138 experimental BPSS1494 (virG) T6SS00077 insolico protein TCS-HK; BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2037977..2038714 (-) 490663798 BPSS1495 (virA) (↓)
REG0139 experimental BPSL1105 (bprP) T6SS00077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 chromosome (NC_006350) 1275668..1276300 (+) 490290369 tssA expression (↓)
REG0140 experimental bprp - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (HM447214) 175..1146 (+) 298239796 tssA expression (↓)
REG0141 experimental bsaN - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (-) - - tssA expression (↓)
REG0142 experimental bspR - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (HM358865) 258..890 (+) 298239780 tssA expression (↓)
REG0143 experimental bprc - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (-) - - tssA expression (↓)
REG0144 experimental BPSS1520 (bprC) T6SS00077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 chromosome (NC_006351) 2072125..2073186 (-) 499518995 tssA expression (↓)
REG0145 experimental BPSS1495 (virA) T6SS00077 insolico protein TCS-HK Burkholderia pseudomallei K96243 chromosome (NC_006351) 2038711..2040555 (-) 53722517 hcp1 expression (↓)
REG0146 experimental BPSS1494 (virG) T6SS00077 insolico protein TCS-RR Burkholderia pseudomallei K96243 chromosome (NC_006351) 2037977..2038714 (-) 53722516 hcp1 expression (↓)
REG0147 experimental FTT1557c/FNU0663.2 (pmrA) T6SS00081 experimental protein TCS-RR Francisella tularensis subsp tularensis SCHU S4 chromosome (NC_006570) 1618742..1619428 (-) 489108239 T6SS transcription (↓)
REG0148 experimental PSYR_RS19090 (relA) T6SS00086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 4380642..4382885 (-) 499587809 T6SS transcripts (↓)
REG0149 experimental PSYR_RS01070 (spoT) T6SS00086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 223004..225109 (-) 489499092 T6SS transcripts (↓)
REG0150 experimental Psyr_3698 (gacS) T6SS00086 experimental protein TCS-HK Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 4385550..4388303 (+) 499587812 T6SS transcription (↓)
REG0151 experimental Psyr_4339 (ladS) T6SS00086 experimental protein QS regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 5191591..5193585 (-) 639463044 T6SS transcription (↓)
REG0152 experimental Psyr_4408 (retS) T6SS00086 experimental protein QS regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 5270882..5273671 (+) 489494774 T6SS transcription (↑)
REG0153 experimental BTH_I1281 (OxyR) T6SS00113 experimental protein Global regulator Burkholderia thailandensis E264 chromosome (NC_007651) 1432632..1433591 (+) 497575020 BTH_RS09735 (T6SS-4) Promotor,−536 to −186 relative to the ATG start codon (↑)
REG0154 experimental bth_I0691 (Zur) T6SS00113 experimental protein Global regulator Burkholderia thailandensis E264 chromosome (NC_007651) 796074..796538 (-) 497578547 BTH_RS09735 (T6SS-4) Promotor,−541 to −1 relative to the ATG start codon (↑)
REG0155 experimental BTH_II1510 (BtaR1) T6SS00115 experimental protein QS regulatory pathway Burkholderia thailandensis E264 chromosome (NC_007650) 1779070..1779789 (-) 497583165 BTH_I2691/BTH_I2693-99/BTH_I2701-702 (↓)
REG0156 experimental pvfC T6SS00125 insolico protein Global regulator Pseudomonas entomophila L48 chromosome (NC_008027) - - T6SS secreted proteome (↓)
REG0157 experimental rmsF T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PA103 chromosome (NZ_JARI00000000) - - tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental PA14_52570 (RsmA) T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0159 experimental PA14_RS20260/PA1120 (YfiN/TpbB) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4435431..4436738 (-) 489207392 Hcp1 production (↓)
REG0160 experimental PA14_RS15060 (PA2133 phosphodiesterase) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 3294000..3294857 (-) 489200657 Hcp1 production (↑)
REG0161 experimental PA14_RS06615 (WspR) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1413158..1414201 (+) 489183089 Hcp1 production (↓)
REG0164 experimental PA14_RS05020 (LadS) T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1069280..1071716 (+) 15599169 Unknown
REG0165 experimental PA14_64230/PA4856 (RetS) T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 5722815..5725643 (+) 489202068 Unknown
REG0166 experimental PA14_45960 (lasR) T6SS00152 experimental; T6SS00151 experimental; T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4085339..4086058 (-) 489173455 TssA2 (PA14_43050) promotor (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0167 experimental PA14_51340 (MvfR) T6SS00152 experimental; T6SS00151 experimental; T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4562837..4563835 (+) 489176730 Upstream of pqs operon (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0168 experimental PA14_51380 (pqsE) T6SS00150 experimental; T6SS00152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4566077..4566982 (-) 489176725 T6SS Transciption (↓)
REG0169 experimental PA14_22470 (PA3225) T6SS00150 experimental; T6SS00152 experimental; T6SS00151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1955624..1956553 (-) 489182081 PA14_00990 (TssA) promotor (↓); TssA1 (PA14_00990) transcript (↑); TssA2 (PA14_43050) transcript (↑); TssB3 (PA14_34070) transcript (↑)
REG0170 experimental PA14_20290 (AmrZ) T6SS00150 experimental; T6SS00152 experimental; T6SS00151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1747602..1747928 (-) 489182353 TssA1 (PA14_00990) promotor (↓); TssA2 (PA14_43050) promotor (↑); TssB3 (PA14_34070) promotor (↓)
REG0171 experimental APECO1_487 (FNR) T6SS00155 insolico protein Global regulator Escherichia coli APEC O1 chromosome (NC_008563) 1455411..1456163 (-) 446534565 APECO1_1756 (VgrG1) (↓)
REG0172 experimental PA14_48150 (QslA) T6SS00152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4286222..4286536 (+) 489177206 H2-T6SS (PA14_43050) promotor (↑)
REG0173 experimental FTN_RS06610 (mglA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1362282..1362899 (+) 489124662 iglC transcription (↓); Unknown (↓)
REG0174 experimental FTN_RS02845 (SspA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 574840..575472 (+) 500053699 FTN_1465 (pmrA) (↓)
REG0175 experimental FTN_RS08805 (KdpD) T6SS00158 experimental protein TCS-HK Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1838601..1841282 (-) 489131611 FTN_1465 (pmrA) (↓)
REG0176 experimental FTN_1465 (pmrA) T6SS00158 experimental protein TCS-RR; TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1553358..1554044 (-) 489108239 FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimental FTN_RS06615 (mglB) T6SS00158 experimental protein Global regulator; TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1362901..1363308 (+) 489112095 IglA expression (↓); T6SS Transciption (↓)
REG0178 experimental FTN_0480 (fevR/PigR) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 486541..486876 (+) 489108070 T6SS Transciption (↓)
REG0179 experimental A1S_0268 (hns) T6SS01000 insolico protein Global regulator Acinetobacter baumannii ATCC 17978 chromosome (CP000521) 292215..292541 (+) - A1S_1292 Transcript (↑)
REG0180 experimental VC0395_RS17530 (TsrA) T6SS00208 insolico; T6SS00487 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009457) 2598392..2598676 (-) 445982516 T6SS Transciption (↑)
REG0181 experimental VC0395_0020/VCA0117 (bEBP/vasH) T6SS00208 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009456) 22315..23907 (-) 446006938 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓)
REG0182 experimental VC0395_A2109 (rpoN) T6SS00208 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009457) 2265078..2266541 (+) 446727517 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓); hcp promoter (PVCA0017/VC0395_0116) (↓)
REG0183 experimental Mmwyl1_1758 (bEBP/vasH) T6SS00216 insolico protein Global regulator Marinomonas sp MWYL1 chromosome (NC_009654) 1985170..1986666 (+) 501016781 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0184 experimental Mmwyl1_2418 (RpoN) T6SS00216 insolico protein Global regulator Marinomonas sp MWYL1 chromosome (NC_009654) 2725212..2726687 (+) 501017436 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0185 experimental YpsIP31758_3980 (ompR) T6SS00225 experimental protein TCS-RR Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 4465260..4465979 (-) 490527984 T6SS-4 promoter (↓)
REG0186 experimental YpsIP31758_3441 (lptD) T6SS00225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0187 experimental YPK_3449 (RelA) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3783755..3785989 (-) 488138165 YPK_1551 (RovM) (↓); YPK_1876 (RovA) (↓)
REG0188 experimental YPK_1876 (RovA) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 2082384..2082815 (+) 488139747 T6SS-4 promoter region (↓); T6SS-4 promoter region (↓)
REG0189 experimental YPK_4079 (OxyR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 4502978..4503895 (-) 488138270 T6SS-4 promoter region (↓)
REG0190 experimental ypk_3425 (RpoS) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3759239..3760237 (-) 499505140 T6SS-4 promoter region (↓)
REG0191 experimental YPK_1551 (RovM) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1713682..1714884 (-) 499506038 T6SS-4 promoter region (↓)
REG0192 experimental YPK_3567 (RovC) T6SS00260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3929654..3930397 (+) 170025782 YPK_3567 promotor (↓)
REG0193 experimental YPK_3372 (CsrA) T6SS00260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3698608..3698793 (-) 169752121 YPK_3567 (RovC) (↑); YPK_3563 transcript (↑)
REG0194 experimental YPK_2462 (HpaR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 2695107..2695574 (+) 169751221 T6SS4 promoter (↓)
REG0195 experimental YPK_RS08345 (YpsR) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1837676..1838413 (+) 488140651 T6SS transcripts (↓)
REG0196 experimental YPK_RS03965 (YtbR) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 900476..901219 (+) 488140447 T6SS transcripts (↓)
REG0197 experimental YPK_RS08350 (ypsI) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1838406..1839050 (-) 501053391 T6SS transcripts (↓)
REG0198 experimental YPK_RS03970 (ytbI) T6SS00256 insolico; T6SS00260 experimental protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 901200..901850 (-) 488144695 T6SS transcripts (↓); T6SS4 transcripts and hcp secretion (↓)
REG0199 experimental YPK_RS00840 (OmpR) T6SS00260 experimental protein TCS-RR Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 223260..223979 (+) 488137706 T6SS4 promoter (↓)
REG0200 experimental YPK_RS01520 (ZntR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 333471..333896 (+) 488144494 T6SS4 promoter (↓)
REG0201 experimental PMI0271 (MrpJ) T6SS00272 experimental protein Global regulator Proteus mirabilis HI4320 chromosome (NC_010554) 318458..318781 (+) 490365253 PMI0749 (tssA); PMI2990 (idsA/hcp)
REG0202 experimental PXO_RS20535 T6SS00287 experimental protein Unknown Xanthomonas oryzae pv oryzae PXO99A chromosome (NC_010717) 4488457..4488843 (-) 499576999 Unknown (↓)
REG0203 experimental KP1_3314 (hns) T6SS00344 experimental protein Global regulator Klebsiella pneumoniae subsp pneumoniae NTUH-K2044 chromosome (NC_012731) 3140175..3140582 (+) 238895262 KP1_2392 (TssB) promotor (↑); KP1_2392 (hcp) (↑)
REG0204 experimental NT01EI_RS04325 (EsrB) T6SS00346 experimental protein TCS-RR Edwardsiella ictaluri 93-146 chromosome (NC_012779) 955101..955745 (-) 506350644 T6SS translocon protein EvpC secretion (↓)
REG0205 experimental NT01EI_RS04200 (EsrC) T6SS00346 experimental protein TCS regulatory pathway Edwardsiella ictaluri 93-146 chromosome (NC_012779) 933326..934018 (-) 737638726 T6SS translocon protein EvpC secretion (↓)
REG0206 experimental ETAE_2873 (RpoS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3025094..3026080 (-) 502612732 ETAE_0886 (esrB) promoter (↑)
REG0207 experimental ETAE_0035 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 35881..37008 (+) 502609898 ETAE_0886 (esrB) promoter (↑)
REG0208 experimental ETAE_0154 (hemB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 159867..160889 (+) 502610017 ETAE_0886 (esrB) promoter (↑)
REG0209 experimental ETAE_0743 (cdsA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 820052..820909 (+) 502610607 ETAE_0886 (esrB) promoter (↑)
REG0210 experimental ETAE_2082 (pyrF) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)
REG0211 experimental ETAE_1096 (dapA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1194778..1195659 (+) 502610962 ETAE_0886 (esrB) promoter (↑)
REG0212 experimental ETAE_2697 (cysS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2831230..2832615 (-) 502612557 ETAE_0886 (esrB) promoter (↑)
REG0213 experimental ETAE_1760 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1870377..1870535 (+) 267984768 ETAE_0886 (esrB) promoter (↑)
REG0214 experimental ETAE_1837 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1946159..1946284 (-) 267984845 ETAE_0886 (esrB) promoter (↑)
REG0215 experimental ETAE_1202 (ugd) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1306603..1307769 (+) 502611067 ETAE_0886 (esrB) promoter (↑)
REG0216 experimental ETAE_2640 (holA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2779832..2780866 (+) 502612494 ETAE_0886 (esrB) promoter (↑)
REG0217 experimental ETAE_1439 (ruvA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1550776..1551384 (+) 502611302 ETAE_0886 (esrB) promoter (↑)
REG0218 experimental ETAE_0358 (purA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 403538..404836 (+) 502610221 ETAE_0886 (esrB) promoter (↑)
REG0219 experimental ETAE_2813 (iscA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2952011..2952334 (-) 491431780 ETAE_0886 (esrB) promoter (↑)
REG0220 experimental ETAE_2787 (guaB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2925310..2926776 (-) 502612646 ETAE_0886 (esrB) promoter (↑)
REG0221 experimental ETAE_1412 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1522924..1523409 (-) 502611274 ETAE_0886 (esrB) promoter (↑)
REG0222 experimental ETAE_0430 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 473075..473755 (-) 502610291 ETAE_0886 (esrB) promoter (↑)
REG0223 experimental ETAE_0659 (aceE) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 731608..734271 (+) 502610523 ETAE_0886 (esrB) promoter (↑)
REG0224 experimental ETAE_2773 (mtnN) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2910743..2911441 (+) 502612632 ETAE_0886 (esrB) promoter (↑)
REG0225 experimental ETAE_2468 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2598484..2599356 (-) 504339400 ETAE_0886 (esrB) promoter (↑)
REG0226 experimental ETAE_1614 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1721332..1722024 (-) 754045576 ETAE_0886 (esrB) promoter (↑)
REG0227 experimental ETAE_0994 (Lon) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1085063..1087288 (+) 267984010 ETAE_0886 (esrB) promoter (↓)
REG0228 experimental ETAE_3542 (phoU) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3747537..3748268 (+) 502613380 ETAE_0886 (esrB) promoter (↓)
REG0229 experimental ETAE_3449 (tpiA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3637381..3638145 (+) 502613286 ETAE_0886 (esrB) promoter (↓)
REG0230 experimental ETAE_1655 (prc) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1757898..1759940 (+) 735677771 ETAE_0886 (esrB) promoter (↓)
REG0231 experimental ETAE_1158 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1257412..1258584 (+) 502611022 ETAE_0886 (esrB) promoter (↓)
REG0232 experimental ETAE_0772 (tadA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 850367..850879 (+) 505698653 ETAE_0886 (esrB) promoter (↓)
REG0233 experimental ETAE_0695 (mrcB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 766885..769368 (+) 502610560 ETAE_0886 (esrB) promoter (↓)
REG0234 experimental ETAE_1170 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1271304..1271447 (-) 267984186 ETAE_0886 (esrB) promoter (↓)
REG0235 experimental ETAE_1562 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1668753..1670378 (-) 780104675 ETAE_0886 (esrB) promoter (↓)
REG0236 experimental ETAE_3453 (cpxR) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3641204..3641902 (+) 502613290 ETAE_0886 (esrB) promoter (↓)
REG0237 experimental ETAE_0263 (mltC) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 293215..294306 (-) 1392602598 ETAE_0886 (esrB) promoter (↓)
REG0238 experimental ETAE_0542 (slt) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 588958..590886 (+) 502610404 ETAE_0886 (esrB) promoter (↓)
REG0239 experimental ETAE_2638 (leuS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2776570..2779152 (+) 502612492 ETAE_0886 (esrB) promoter (↓)
REG0240 experimental ETAE_3207 (rplQ) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3390207..3390593 (-) 491439763 ETAE_0886 (esrB) promoter (↓)
REG0241 experimental ETAE_1010 (acrB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1099309..1102461 (-) 502610875 ETAE_0886 (esrB) promoter (↓)
REG0242 experimental ETAE_1425 (mviN) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1535368..1536906 (+) 502611288 ETAE_0886 (esrB) promoter (↓)
REG0243 experimental ETAE_0886 (EsrB) T6SS00372 experimental protein TCS-RR Edwardsiella tarda EIB202 chromosome (NC_013508) 964658..965302 (-) 502610749 Unknown (↓); Unknown (↓)
REG0244 experimental ETAE_2059 (phoP) T6SS00372 experimental protein TCS-HK Edwardsiella tarda EIB202 chromosome (NC_013508) 2172565..2173239 (+) 502611910 ETAE_0886 (EsrB) (↓)
REG0245 experimental ETAE_3098 (PepA) T6SS00372 experimental protein Transcription regulator Edwardsiella tarda EIB202 chromosome (NC_013508) 3260322..3261833 (+) 502612947 ETAE_0886 (esrB) promoter (↑)
REG0246 experimental ETAE_3474 (fabR) T6SS00372 experimental protein QS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3666488..3667159 (-) 502613311 Unknown (↓)
REG0247 experimental ETAE_1505 (H-NS) T6SS00372 experimental protein Transcription regulator Edwardsiella tarda EIB202 chromosome (NC_013508) 1615099..1615506 (-) 505274277 ETAE_2430 (evpB) (↑); evpC promotor (↑)
REG0248 experimental EC042_RS26480 (aggR) T6SS00464 experimental protein Transcription regulator Escherichia coli 042 plasmid (NC_017627) 41080..41877 (-) 446692110 EC042_RS26480 (aggR) promoter (↓); EC042_RS26480 (aggR) promoter (↓)
REG0249 experimental EC042_RS18855 (FIS) T6SS00464 experimental protein Transcription regulator Escherichia coli 042 chromosome (NC_017626) 3772795..3773091 (+) 446385050 EC042_RS26480 (aggR) promoter (↓)
REG0250 experimental EC042_RS06800 (Hns) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 1376831..1377244 (-) 447210122 EC042_RS26480 (aggR) promoter (↑)
REG0251 experimental EC042_RS03685 (Fur) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 786918..787364 (-) 446053847 EC042_4532 promoter (↑); EC042_4524 (TssB) promotor (↑)
REG0252 experimental EC042_RS19435 (Dam) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 3861171..3862007 (-) 446664793 EC042_4532 promoter (↑)
REG0253 experimental PAM18_RS12360 (gacA) T6SS00612 insolico; T6SS00613 insolico; T6SS00611 insolico protein TCS-RR Pseudomonas aeruginosa M18 chromosome (NC_017548) 2625815..2626459 (+) 489180874 hsiA1 operon transcript (↓); hsiA2 operon transcript (↓); hsiA3 operon transcript (↓)
REG0254 experimental VasH T6SS00788 experimental protein Transcription regulator Aeromonas hydrophila strain SSU chromosome (DQ667172) 15458..16996 (+) 110277136 hcp expression (↓)
REG0255 experimental ahyI T6SS00788 experimental protein QS regulatory pathway Aeromonas hydrophila strain SSU chromosome (DQ398101) 843..1466 (+) 89027174 ahyR (↓)
REG0256 experimental ahyR T6SS00788 experimental protein QS regulatory pathway Aeromonas hydrophila strain SSU chromosome (DQ398101) 1..783 (-) 89027173 hcp and vgrG2 expression (↓)
REG0257 experimental VEPGS_0614 (PppA) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 15765..16880 (+) 225382180 LuxR (↓)
REG0258 experimental VEPGS_0606 (PpkA2) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 3227..5377 (-) 225382172 LuxR (↓); VEPGS_0610 (DotU2) (↓)
REG0259 experimental VEPGS_0607 (Fha2) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 5690..6775 (+) 225382173 VEPGS_0610 (DotU2) (↓)
REG0260 experimental EPGS_00471 (VtsR) T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - LuxO (↓)
REG0261 experimental EPGS_00471 (VtsR) T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - LuxO (↑)
REG0262 experimental luxR T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - T6SS2 transcript and expression (↓)
REG0263 experimental luxR T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript and expression (↑)
REG0264 experimental VEPGS_0621 (pppA) T6SS00793 experimental protein Tpp; QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) 23577..24245 (+) 225382187 Unknown (↑); T6SS1 transcript (↑); hcp1 transcript (↓)
REG0265 experimental luxS T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - hcp1 transcript (↓)
REG0266 experimental LuxO T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - hcp1 transcript (↓)
REG0267 experimental LuxO T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - Unknown (↑)
REG0268 experimental rpoN T6SS00793 experimental protein Transcription regulator Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript (↓)
REG0269 experimental VasH T6SS00793 experimental protein Transcription regulator Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript (↓)
REG0270 experimental CXG97_03740 (Fur) T6SS00904 experimental protein Transcription regulator Escherichia coli strain ExPEC XM chromosome (NZ_CP025328) 729474..729920 (-) 446053847 T6SS1 (TssB) promotor (↑)
REG0271 experimental H1D38_08255 (fur) T6SS00931 experimental protein Global regulator Escherichia coli strain 17-2 chromosome (JACEFV010000001) 1744748..1745194 (-) MBA2233871.1 sciH promotor (↑)
REG0272 experimental H1D38_12840 (Dam) T6SS00931 experimental protein Global regulator Escherichia coli strain 17-2 chromosome (JACEFV010000002) 105877..106713 (+) MBA2234741.1 sciH promotor (↑)
REG0273 experimental W817_21870 (CpxR) T6SS00937 experimental protein TCS-RR Escherichia coli RS218 chromosome (NZ_CP007149) 4360812..4361510 (-) 446956464 hcp2B promoter (↓)
REG0274 experimental W817_01610 (NplE) T6SS00937 experimental protein TCS regulatory pathway Escherichia coli RS218 chromosome (NZ_CP007149) 214947..215657 (+) 446161331 W817_RS21690 (CpxA) (↓)
REG0275 experimental V12G01_21538 (LuxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009644 chromosome (AAPS01000053) 13551..14165 (-) 91187814 T6SS2 transcripts (↓)
REG0276 experimental V12G01_19736 (TfoX) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009693 chromosome (AAPS01000019) 47689..48276 (-) 91189146 T6SS2 transcripts (↓)
REG0277 experimental V12G01_20658 (TfoY) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009646 chromosome (AAPS01000015) 63783..64190 (+) 91189474 T6SS transcripts (↓)
REG0278 experimental V12G01_20201 (H-NS) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009646 chromosome (AAPS01000015) 63783..64190 (+) 91189474 VaT6SS1 transcripts (↑)
REG0279 experimental V12G01-18672 (vqsA) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009692 chromosome (AAPS01000003) 114208..115086 (+) 91191289 V12G01-21538 (luxR) promoter (↓); V12G01-14830 (aphA) promoter (↓); V12G01-18672 (vqsA) promotor (↓)
REG0280 experimental V12G01_10813 (AsnC) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0281 experimental V12G01_02325 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 115263..116411 (+) 91190993 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0282 experimental V12G01_01665 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009655 chromosome (AAPS01000007) 185299..185712 (+) 91190406 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0283 experimental V12G01_06711 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009529 chromosome (AAPS01000024) 47707..48585 (-) 91188835 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0284 experimental V12G01_16177 (MetR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009686 chromosome (AAPS01000023) 58420..59331 (-) 91188901 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0285 experimental V12G01_02620 (SoxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0286 experimental V12G01_21538 (luxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009644 chromosome (AAPS01000053) 13551..14165 (-) 91187814 V12G01-18672 (vqsA) promotor
REG0287 experimental V12G01-14830 (aphA) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009682 chromosome (AAPS01000027) 42305..42880 (+) 91188695 V12G01-18672 (vqsA) promotor
REG0288 experimental VCA1552_03277/VCA0566 (VxrB) T6SS00002 experimental protein TCS-RR Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 504728..505384 (+) 446737785 Unknown (↑)
REG0289 experimental VCA0933 (CspV) T6SS00002 experimental protein c-di-GMP regulatory pathway Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 886068..886280 (+) 446027150 Unknown (↓)
REG0290 experimental VCA1552_01380 (VdcA/ycdT) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1482426..1483715 (+) 446892247 the levels of c-di-GMP (↑)
REG0291 experimental VCA1552_02536 (CdpA/YfgF) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2739669..2742158 (-) 446417730 the levels of c-di-GMP (↓)
REG0292 experimental VCA1552_02898 (VasH) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024868) 128889..130481 (+) 446006938 VCA1552_00900 (TfoX) (↓)
REG0293 experimental VCA1552_00351 (HapR) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 340447..341058 (-) 446262243 Unknown; Hcp expression and secretion
REG0294 experimental VCA1552_RS04890 (ihfA) T6SS01112 experimental protein Transcription regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1028170..1028466 (+) 447152004 Hcp secretion (↓)
REG0295 experimental VCA1552_RS08565 (ihfB) T6SS01112 experimental protein Transcription regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1839353..1839631 (-) 446089486 Hcp secretion (↓)
REG0296 experimental VCA1552_RS03895 (LuxO) T6SS01112 experimental protein QS regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 818142..819509 (+) 487814784 Hcp expression and secretion (↑)
REG0297 experimental VCA1552_RS17020 (cqsa) T6SS01112 experimental protein QS regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024868) 455238..456407 (-) 446962656 Hcp expression and secretion (↓)
REG0298 experimental VCA1552_RS01665 (LuxS) T6SS01112 experimental protein QS regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 319588..320106 (+) 447052971 Hcp expression and secretion (↓)
REG0299 experimental VCA1552_RS00505 (hfq) T6SS01112 experimental protein QS regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 92673..92936 (+) 446974616 VCA1552_00351 (HapR) (↑)
REG0300 experimental VCA1552_RS11610 (RpoN) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2488023..2489486 (+) 446727517 Hcp expression and secretion (↓)
REG0301 experimental VCA1552_RS12025 (crp) T6SS01112 experimental protein QS regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2558371..2559003 (+) 446164894 Hcp expression and secretion (↓)
REG0302 experimental VCA1552_RS12925 (cya) T6SS01112 experimental protein QS regulatory pathway; cAMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2747346..2749877 (-) 447072406 VCA1552_RS12025 (crp) (↓)
REG0303 experimental VC0396/VCA1552_00154 (QstR) T6SS01112 experimental protein c-di-GMP regulatory pathway; QS regulatory pathway; Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 149920..150564 (-) 447111060 TssB/ TfoY transcripts (↓); VC0396/VCA1552_00154 (QstR) (↓); T6SS transcripts (↓)
REG0304 experimental VCA1552_00900 (TfoX) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 952868..953476 (+) 487807468 VC0396/VCA1552_00154 (QstR) (↓)
REG0305 experimental VCA1552_00154 (QstR) T6SS01112 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway; Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 149920..150564 (-) 447111060 Unknown (↓)
REG0306 experimental VCA1552_01510 (TfoY) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1636980..1637567 (+) 446282733 Unknown (↓)
REG0307 experimental VCA1552_RS06160 (lonA) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1315238..1316887 (+) 446116573 VCA1552_01510 (TfoY) (↑)
REG0308 experimental VCA1552_RS10420 (cdgL) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2215844..2217361 (-) 446975354 the levels of c-di-GMP (↓)
REG0309 experimental VCA1552_RS04310 (cdgK) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 901594..903063 (+) 487807420 the levels of c-di-GMP (↓)
REG0310 experimental VCA1552_RS04130 (cdgH) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 861187..863208 (+) 446848493 the levels of c-di-GMP (↓)
REG0311 experimental VCA1552_RS02130 (rocS) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 425233..427287 (-) 447034155 the levels of c-di-GMP (↑)
REG0312 experimental VCA1552_RS12850 (cdgJ) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2733319..2734545 (-) 446210986 the levels of c-di-GMP (↑)
REG0313 experimental VCA1552_RS17835 (cdgD) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024868) 633312..635195 (+) 446210820 the levels of c-di-GMP (↓)
REG0314 experimental TfoY T6SS00790 experimental protein Global regulator Vibrio cholerae V52 chromosome (NZ_AAKJ02000013) - - Unknown (↓)
REG0315 experimental VCV52_1108 (TfoX) T6SS00790 experimental protein Global regulator Vibrio cholerae V52 chromosome (NZ_KQ410501) 68827..69435 (-) 487807468 Unknown (↓)
REG0316 experimental VCV52_RS01020 (VasH) T6SS00790 experimental protein Global regulator Vibrio cholerae V52 chromosome (NZ_KQ410497) 212259..213851 (-) 446006947 Unknown (↓)
REG0317 experimental VCV52_RS13040 (rpoN) T6SS00790 experimental protein Global regulator Vibrio cholerae V52 chromosome (NZ_KQ410502) 216932..218395 (-) 446727517 Unknown (↓)
REG0318 experimental Y113_RS04835 (esrC) T6SS00791 experimental protein TCS-HK Edwardsiella tarda strain PPD130/91 chromosome (NZ_JACQ01000008) 20632..23367 (-) 1624663318 EvpQ protein level (↓)
REG0319 experimental Y113_RS04830 (esrB) T6SS00791 experimental protein TCS-RR Edwardsiella tarda strain PPD130/91 chromosome (NZ_JACQ01000008) 20006..20635 (+) 1940020585 EvpA and EvpC protein concentration (↓)
REG0320 experimental VC_A0122 T6SS00002 experimental protein Transcription regulator Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 137379..137621 (+) 9657509 hcp-2 expression (↓)
REG0321 experimental GT391_RS06470 (expR1) T6SS01170 experimental protein QS regulatory pathway Pectobacterium brasiliense strain 1692 chromosome (NZ_CP047495) 1453704..1455596 (+) 746272689 T6SS transcripts (↓)
REG0322 experimental GT391_RS06405 (expI) T6SS01170 experimental protein QS regulatory pathway Pectobacterium brasiliense strain 1692 chromosome (NZ_CP047495) 1436931..1437581 (-) 497970044 GT391_RS06470 (expR1) (↓)
REG0323 experimental GT391_RS16925 (phoP) T6SS01170 experimental protein TCS-HK Pectobacterium brasiliense strain 1692 chromosome (NZ_CP047495) 3795787..3796476 (-) 497961604 GT391_RS06470 (expR1) (↑)
REG0324 experimental WQ49_05050 (cepR) T6SS01276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 scf7180000000049 chromosome (LAUA01000002) 545988..546707 (-) 815852483 T6SS promotor (P (BCAL0340) ) (↓)
REG0325 experimental WQ49_20245 (cciR) T6SS01276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 scf7180000000062 chromosome (LAUA01000016) 843677..844378 (+) 815850423 Unknown (↑)
REG0326 experimental WQ49_19595/BCAM0379 (atsR) T6SS01276 experimental protein TCS-RR Burkholderia cenocepacia strain K56-2 scf7180000000062 chromosome (LAUA01000016) 710895..712715 (+) 815849700 T6SS transcripts (↑); T6SS expression (↑)
REG0327 experimental WQ49_05060 (cepI) T6SS01276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 scf7180000000049 chromosome (LAUA01000002) 547435..548043 (+) 815852485 T6SS expression (↓)
REG0328 experimental WQ49_20250 (cciI) T6SS01276 experimental protein QS regulatory pathway Burkholderia cenocepacia strain K56-2 scf7180000000062 chromosome (LAUA01000016) 844665..845255 (+) 815850424 T6SS expression (↓)
REG0329 experimental VPBB_RS05425 (H-NS) T6SS00719 experimental protein Transcription regulator Vibrio parahaemolyticus BB22OP chromosome (NC_019955) 1170475..1170882 (-) 505109423 VgrG1 expression and secretion (↑)
REG0330 experimental Pchl3084_4333 (gacS) T6SS01266 insolico; T6SS01267 insolico protein TCS-RR Pseudomonas chlororaphis subsp aureofaciens 30-84 chromosome (NZ_CM001559) 5113748..5116501 (+) 496335944 Pchl3084_3491 (gacA) (↓)
REG0331 experimental Pchl3084_3491 (gacA) T6SS01266 insolico; T6SS01267 insolico protein TCS-HK Pseudomonas chlororaphis subsp aureofaciens 30-84 chromosome (NZ_CM001559) 4134794..4135435 (-) 496335231 Pchl3084_5419 (rsmY)promotor (↓); Pchl3084_1190 (rsmZ)promotor (↓); Pchl3084_1189 (rpoS)transcript (↓)
REG0332 experimental GacS T6SS01269 experimental protein TCS-RR Pseudomonas aeruginosa cystic fibrosis isolate CHA chromosome (-) - - hcp1 expression and secretion (↑)
REG0333 experimental rsmA T6SS01269 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa cystic fibrosis isolate CHA chromosome (-) - - hcp1 expression and secretion (↑)
REG0334 experimental PSA3335_RS05390 (iaaM) T6SS01041 insolico protein IAA regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 chromosome (NZ_CP008742) 1090961..1092634 (-) 488619197 The transcript levels of vgrG (↓)
REG0335 experimental PSA3335_RS05385 (iaaH) T6SS01041 insolico protein IAA regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 chromosome (NZ_CP008742) 1089578..1090918 (-) 488619198 The transcript levels of vgrG (↓)
REG0336 experimental BWP10_01550 (ssrB) T6SS01291 experimental protein TCS-RR Salmonella enterica subsp enterica serovar Typhimurium strain ATCC 14028 chromosome (MTFW01000001) 296600..299362 (+) 1145677935 sciS/TssM transcription (↑)
REG0338 experimental BN49_2224 (phoQ) T6SS01214 experimental protein TCS-RR Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 2324171..2325637 (-) 490249900 TssB transcription (↓)
REG0339 experimental BN49_2225 (phoP) T6SS01214 experimental protein TCS-HK Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 2325637..2326308 (-) 490252783 BN49_2224 (phoQ) (↓)
REG0340 experimental BN49_RS29275 (mgrB) T6SS01214 experimental protein TCS regulatory pathway Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 3583038..3583181 (-) 489000713 phoPQ (↑)
REG0341 experimental BN49_3854 (rcsB) T6SS01214 experimental protein TCS-RR Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 4066268..4066918 (+) 489002368 phoPQ (↑)
REG0342 experimental BN49_3310 (h-ns) T6SS01214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 3427636..3428043 (+) 488999426 TssB transcription (↑)
REG0343 experimental BN49_1760 (fur) T6SS01214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 1826878..1827330 (-) 514077307 TssB transcription (↓)
REG0344 experimental BN49_4862 (hfq) T6SS01214 experimental protein QS regulatory pathway Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 5173711..5174019 (-) 488974767 TssB transcription (↓)
REG0345 experimental BN49_0508 (rpoN) T6SS01214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 533564..534997 (-) 489007850 TssB transcription (↓)
REG0346 experimental BN49_1023 (rpoS) T6SS01214 experimental protein Global regulator Klebsiella pneumoniae strain Kp52.145 chromosome (NZ_FO834906) 1060243..1061235 (+) 489004494 TssB transcription (↓)
REG0347 experimental sdiA - protein Global regulator Enterobacter cloacae strain JLD400 chromosome (-) - - ENC_07270 transcript (↓)
REG0348 experimental SMDB11_2275/SMA2275 (PpkA) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2399154..2400599 (+) 560174118 SMDB11_2267/SMA2267 (Fha) (↓); SMDB11_2267/SMA2267 (Fha) (↑)
REG0349 experimental SMDB11_2267/SMA2267 (Fha) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2388490..2390232 (+) 560174110 Unknown (↓)
REG0350 experimental F9K57_RS04510 (VgrGi) T6SS01164 experimental protein Global regulator Acinetobacter baumannii strain AbCAN2 chromosome (NZ_CP045428) 925473..928592 (+) 1797381381 T6SS structure (↑)
REG0351 experimental PSEBR_RS22825 (GacS) T6SS00431 insolico; T6SS00432 insolico protein TCS-RR Pseudomonas brassicacearum subsp brassicacearum NFM421 chromosome (NC_015379) 5188012..5190762 (+) 503459407 hcp1 transcript (↓)
REG0352 experimental - T6SS00431 insolico; T6SS00432 insolico protein TCS-RR Pseudomonas brassicacearum subsp brassicacearum NFM421 chromosome (NC_015379) 5188012..5190762 (+) 503459407 hcp2 transcript (↓)
REG0353 experimental AHA_1842 (VasH) T6SS00157 experimental protein QS regulatory pathway Aeromonas hydrophila subsp hydrophila ATCC 7966 chromosome (NC_008570) 2010521..2012059 (+) 117617496 T6SS gene cluster promoter (PAHA1826) (↓)
REG0354 experimental AHA_3923 (rpoN) T6SS00157 experimental protein Global regulator Aeromonas hydrophila subsp hydrophila ATCC 7966 chromosome (NC_008570) 4350676..4352115 (-) 117618923 T6SS gene cluster promoter (PAHA1826) (↓)
REG0355 experimental N779_15250 (VtpR) T6SS01280 experimental; T6SS01281 experimental protein QS regulatory pathway Vibrio coralliilyticus OCN008 chromosome (AVOO01000045) 7579..8184 (-) 536747482 Unknown (↓)
REG0356 experimental W909_RS11820 (VfmH) T6SS01037 insolico protein TCS-RR Dickeya zeae EC1 chromosome (NZ_CP006929) 2699617..2701098 (+) 515507611 T6SS transcripts (↓)
REG0357 experimental PPECC33_RS11180 (BaeS) T6SS01034 experimental protein TCS-HK Escherichia coli PCN033 chromosome (NZ_CP006632) 2271464..2272867 (+) 446597798 PPECC33_RS11185 (BaeR) (↓)
REG0358 experimental PPECC33_RS11185 (BaeR) T6SS01034 experimental protein TCS-RR Escherichia coli PCN033 chromosome (NZ_CP006632) 2272864..2273586 (+) 446060022 T6SS promotor (↓)
REG0359 experimental bglu_1g09700 (tepR) T6SS00343 insolico protein Global regulator Burkholderia glumae BGR1 chromosome (NC_012724) 1045102..1046502 (-) - Unknown (↓)
REG0360 experimental ACX61_19655 (tetR2) T6SS01047 insolico protein Global regulator Acinetobacter baumannii strain Ab04-mff plasmid (NZ_CP012007) 144108..144677 (+) 446104352 hcp secretion (↑)
REG0361 experimental ACX61_19615 (tetR1) T6SS01047 insolico protein Global regulator Acinetobacter baumannii strain Ab04-mff plasmid (NZ_CP012007) 139526..140098 (+) 487938137 hcp secretion (↑)
REG0362 experimental PPECC33_RS11945 (rcsB) T6SS01034 experimental protein TCS-RR Escherichia coli PCN033 chromosome (NZ_CP006632) 2429320..2429970 (+) 446984661 T6SS transcription (↓)
REG0363 experimental vfu_A02134 (ihfA) T6SS00529 insolico; T6SS00530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 chromosome (NC_016602) 2226951..2227244 (-) 490864172 tssD2_a promoter (↓)
REG0364 experimental Y113_RS11250 (RpoS) T6SS00791 experimental protein Transcription regulator Edwardsiella tarda PPD130/91 chromosome (NZ_JACQ01000026) 9122..10108 (-) 502612732 EvpQ transcription and protein level (↑)
REG0365 experimental Y113_RS02460 (Fur) T6SS00791 experimental protein Global regulator Edwardsiella tarda PPD130/91 chromosome (NZ_JACQ01000003) 461902..462351 (+) 735678383 EvpQ protein level (↑)
REG0366 experimental YPK_RS19410 (Zur) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 4251751..4252260 (+) 488143439 T6SS4 transcription (↓)
REG0367 experimental H78_RS02920 (Hfq) - protein QS regulatory pathway Pseudomonas protegens strain H78 chromosome (NZ_CP013184) 662937..663197 (+) 495196588 T6SS transcription level (↓)
REG0368 experimental PA1544 (Anr) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1681071..1681805 (-) 15596741 H2-T6SS transcriptional level and ModA secretion (↓)
REG0369 experimental VCV52_0688 (wigR/phoB/vxrB) T6SS00790 experimental protein TCS-RR Vibrio cholerae V52 chromosome (NZ_KQ410503) 201806..202495 (-) 446013262 T6SS transcription level (↓)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0008 experimental PA0527.1 (RsmY) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 586867..586990 (+) - RsmA (Y880_06257) (↓)
REG0009 experimental PA3621.1 (RsmZ) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4057543..4057658 (-) - RsmA (Y880_06257) (↓)
REG0020 experimental Qrr4 T6SS01061 experimental ncRNA Unknown Vibrio cholerae 2740-80 chromosome (NZ_CP016325) - - VCA0107 mRNA (↑)
REG0025 experimental Qrr1 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0026 experimental Qrr2 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0027 experimental Qrr3 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0028 experimental Qrr4 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0059 experimental PA4704.1 (prrF1) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5283960..5284110 (+) 4179187 T6SS transcripts (↓)
REG0060 experimental PA4704.2 (prrF2) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5284172..5284319 (+) 4179185 T6SS transcripts (↓)
REG0103 experimental CsrB1 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 243728..2439035 (+) - VP_RS12395 (CsrA) (↑)
REG0104 experimental CsrB2 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 3215766..3216162 (-) - VP_RS12395 (CsrA) (↑)
REG0105 experimental CsrB3 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Bacillus megaterium QM B1551 plasmid (NC_004604) 171473..171785 (+) - VP_RS12395 (CsrA) (↑)
REG0162 experimental RsmY T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 596840..596963 (+) Unknown
REG0163 experimental RsmZ T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1500352..1500467 (+) Unknown

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0001 experimental vfu_A02134 (ihfA) T6SS00529 insolico; T6SS00530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 chromosome (NC_016602) 2226951..2227244 (-) 490864172 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0002 experimental vfu_A02422 (ihfB) T6SS00529 insolico; T6SS00530 insolico protein Transcription regulator Vibrio furnissii NCTC 11218 chromosome (NC_016602) 2516092..2516376 (-) 490864456 tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0003 experimental RT90_01105 (rcsC) T6SS01264 experimental protein TCS-HK Serratia marcescens strain RM66262 chromosome (JWLO01000001) 232638..235499 (+) 735006326 RT90_01115 (rcsB) (↑)
REG0004 experimental RT90_01115 (rcsB) T6SS01264 experimental protein TCS-RR Serratia marcescens strain RM66262 chromosome (JWLO01000001) 235561..236211 (-) 735006328 vgrG promoter (↓)
REG0005 experimental RT90_16255 (wecG) T6SS01264 experimental protein TCS regulatory pathway Serratia marcescens strain RM66262 chromosome (JWLO01000003) 92056..92796 (-) 735005313 RT90_01105 (rcsC) (↑)
REG0006 experimental L085_RS13655 (ppka) T6SS01033 experimental protein Tpp Serratia sp FS14 chromosome (NZ_CP005927) 3028273..3029718 (-) 763151328 Unknown (↓)
REG0007 experimental PA4740/Y880_04683 (pnp) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4637120..4639225 (-) 489185761 PA0527.1 (RsmY) (↑); PA3621.1 (RsmZ) (↑)
REG0008 experimental PA0527.1 (RsmY) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 586867..586990 (+) - RsmA (Y880_06257) (↓)
REG0009 experimental PA3621.1 (RsmZ) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico ncRNA RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 4057543..4057658 (-) - RsmA (Y880_06257) (↓)
REG0010 experimental Y880_06257 (rsmA) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 6213838..6214644 (-) 510932573 PA4492 mRNA (↑)
REG0011 experimental Y880_05180 (rmsF) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein RsmA regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5147809..5148024 (-) 489186811 tssA1 expression (↑)
REG0012 experimental Y880_02189 (gacA/uvrY) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein TCS-RR Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 2199690..2200334 (-) 510933056 hcp expression (↓)
REG0013 experimental Y880_03649 (suhB) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein TCS regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 3616623..3617438 (+) 489183406 Y880_02189 (gacA/uvrY) (↓)
REG0014 experimental SMDB11_2275 (PpKA) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2399154..2400599 (+) 560174118 SMDB11_2267 (FHA) (↓)
REG0015 experimental SMDB11_2268 (PppA) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2390232..2391005 (+) 560174111 SMDB11_2267 (FHA) (↑)
REG0016 experimental SMDB11_2269 (RtkS) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2391034..2392020 (+) 560174112 SMDB11_2275 (PpKA) (↓)
REG0017 experimental SMDB11_2256 (TagF) T6SS00929 experimental protein Tpp Serratia marcescens subsp marcescens Db11 chromosome (HG326223) 2380702..2381421 (+) 560174099 Unknown (↑)
REG0018 experimental PA4462 (RpoN) T6SS00003 experimental; T6SS00004 experimental; T6SS00005 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 PA1512 (hcpA) promotor (↓); PA5267 (hcpB) promotor (↓)
REG0019 experimental PC1_3721 (Hfq) T6SS01001 insolico protein QS regulatory pathway Pectobacterium carotovorum subsp carotovorum PC1 chromosome (CP001657) 4199890..4200189 (-) 251756660 hcp expression (↓)
REG0020 experimental Qrr4 T6SS01061 experimental ncRNA Unknown Vibrio cholerae 2740-80 chromosome (NZ_CP016325) - - VCA0107 mRNA (↑)
REG0021 experimental GPY04_RS11195 (CytR) T6SS01168 experimental protein Unknown Vibrio cholerae C6706 chromosome (NZ_CP046844) 2449479..2450486 (-) 446146597 Unknown (↓)
REG0022 experimental GPY04_RS03590 (TfoX) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 777344..777952 (+) 487807468 Unknown (↓)
REG0023 experimental GPY04_RS00870 (HapR) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 164935..165546 (-) 446262243 Unknown (↓)
REG0024 experimental GPY04_RS13335/VC0070 (tsrA) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2888303..2888587 (+) 445982516 T6SS transcripts (↑)
REG0025 experimental Qrr1 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0026 experimental Qrr2 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0027 experimental Qrr3 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0028 experimental Qrr4 quorum regulatory RNA T6SS01168 experimental ncRNA QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) - - VCA0107 mRNA (↑)
REG0029 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046845) 273631..274983 (-) 446367907 VC0070 (tsrA) (↑)
REG0030 experimental GPY04_RS13825 (QstR) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2994333..2994977 (-) 447111060 Unknown (↓)
REG0031 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein Global regulator Vibrio cholerae C6706 chromosome (NZ_CP046844) 2994333..2994977 (-) 447111060 Unknown (↓)
REG0032 experimental GPY04_RS15835 (luxO) T6SS01168 experimental protein QS regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046845) 273631..274983 (-) 446367907 GPY04_RS00870 (hapR) (↑)
REG0033 experimental GPY04_RS01040 (ChiS) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 210606..213995 (-) 446410424 Necessory for TfoX/TfoR (↓)
REG0034 experimental GPY04_RS03200 (chiA2) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 692014..695280 (+) 487807405 GPY04_RS01040 (ChiS) (↓)
REG0035 experimental GPY04_RS07700 (chiA1) T6SS01168 experimental protein ChiS-induced regulatory pathway Vibrio cholerae C6706 chromosome (NZ_CP046844) 1709613..1712153 (-) 446755770 GPY04_RS01040 (ChiS) (↓)
REG0036 experimental VC1920/VCA1552_01695 (LonA) T6SS01112 experimental protein Unknown Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1845472..1847832 (-) 446970355 Unknown (↑)
REG0037 experimental Y880_05519 (dgcP) T6SS01211 insolico; T6SS01212 insolico; T6SS01213 insolico protein c-di-GMP regulatory pathway Pseudomonas aeruginosa PAK chromosome (NZ_CP020659) 5487251..5489266 (-) 489205065 the levels of c-di-GMP (↓)
REG0038 experimental PSA3335_06200 (dgcP) T6SS01041 insolico protein c-di-GMP regulatory pathway Pseudomonas savastanoi pv savastanoi NCPPB 3335 chromosome (NZ_CP008742) 1344347..1346692 (+) 488618048 the levels of c-di-GMP (↓)
REG0039 experimental VC_RS13930 (VasH) T6SS00002 experimental protein Global regulator Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 128790..130382 (+) 446006938 VCA0017 (hcp-2) transcript (↓)
REG0040 experimental PA0592 (RsmA) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental PA5183a (RsmN) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0042 experimental PA0075 (PppA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90106..90834 (-) 15595273 PA0081 (Fha-1/TagH) (↑)
REG0043 experimental PA0074 (PpkA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 87000..90098 (-) 15595272 PA0081 (Fha-1/TagH) (↓)
REG0044 experimental PA2586 (gacA) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2925788..2926432 (-) 15597782 hcp1 (PA0085) expression and secretion (↓)
REG0045 experimental PA0610 (prtN) T6SS00003 experimental protein TCS-HK Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 672777..673091 (-) 15595807 PA0611 (prtR) (↑)
REG0046 experimental PA0611 (prtR) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 673191..673961 (-) 15595808 hcp1 (PA0085) expression and secretion (↑); PA2586 (gacA) (↑)
REG0047 experimental PA0072 (TagS) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 85085..86284 (-) 15595270 PA0073 (TagT) (↓)
REG0048 experimental PA0070 (TagQ) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 82404..83318 (-) 15595268 PA0071 (tagR) (↓)
REG0049 experimental PA0073 (TagT) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 86284..87003 (-) 15595271 PA0072 (TagS) (↓)
REG0050 experimental PA2492 (MexT) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental PA1006 T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0052 experimental PA0071 (tagR) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 83380..85092 (-) 15595269 PA0074 (PpkA) (↓)
REG0053 experimental PA4856 (RetS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5452150..5454978 (+) 15600049 hcp1 (PA0085) expression and secretion (↑)
REG0054 experimental PA3974 (LadS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4453289..4455676 (-) 15599169 hcp1 (PA0085) expression and secretion (↓)
REG0055 experimental PA4109 (AmpR) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0056 experimental PA0076 (TagF) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90844..91524 (-) 15595274 hcp1 (PA0086) secretion (↑)
REG0057 experimental PA0081 (Fha-1/TagH) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 98263..99756 (-) 15595279 Unknown (↓); clpV (↓)
REG0058 experimental PA2976 (RNase E) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0059 experimental PA4704.1 (prrF1) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5283960..5284110 (+) 4179187 T6SS transcripts (↓)
REG0060 experimental PA4704.2 (prrF2) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5284172..5284319 (+) 4179185 T6SS transcripts (↓)
REG0061 experimental PA0996 (pqsA) T6SS00004 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1078462..1080015 (+) 15596193 T6SS transcripts
REG0062 experimental PA1244 (QslA) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1348060..1348401 (-) 15596441 H2-T6SS (PA1656) promotor (↑)
REG0063 experimental PA4778 (CueR) T6SS00004 experimental protein Transcription regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5366257..5366655 (+) 15599972 tssA2 (-173 to -140 relative to the ATG start codon) (↓); hcp2 (-208 to -159 relative to the ATG start codon) (↓)
REG0064 experimental PA4856 (RetS) T6SS00004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5366257..5366655 (+) 15599972 H2-T6SS (↑)
REG0065 experimental PA1430 (LasR) T6SS00004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1558171..1558890 (+) 15596627 H2-T6SS promotor P (hsiA2) (↓)
REG0066 experimental PA3476 (rhlI) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889139..3889744 (-) 15598672 PA3477 (RhlR) (↓)
REG0067 experimental PA3477 (RhlR) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889925..3890650 (-) 15598673 T6SS transcript (↓)
REG0068 experimental PA4764 (Fur) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5351675..5352079 (-) 15599958 H2-T6SS Transcription (↑)
REG0069 experimental PA4462 (rpoN) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 T6SS transcript (↑)
REG0070 experimental pa1663 (sfa2) T6SS00004 experimental; T6SS00005 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1813395..1814906 (+) 15596860 PA4462 (rpoN) (↑); T6SS transcript (↑); T6SS transcript (↓)
REG0071 experimental Z4049 (RpoS) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 3654380..3655372 (-) 446003635 Z1921 (KatN) (↓)
REG0072 experimental Z5519 (OxyR) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 5033893..5034810 (+) 446948683 Z1921 (KatN) (↓)
REG0073 experimental Z2013 (hns) T6SS00006 insolico protein Global regulator Escherichia coli O157:H7 str EDL933 chromosome (NC_002655) 1829490..1829903 (-) 447210122 Z0264 (hcp-2) (↑)
REG0074 experimental PP_4373 (FleQ) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 4963882..4965357 (-) 26991062 K1-T6SS (hcp1) expression (↑)
REG0075 experimental PP_0952 (RopN) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 1094567..1096060 (-) 26987688 PP_4373 (FleQ) (↑)
REG0076 experimental PP_0914 (BifA) T6SS00014 experimental protein c-di-GMP regulatory pathway Pseudomonas putida KT2440 chromosome (NC_002947) 1055990..1058071 (-) 26987650 the levels of c-di-GMP (↓)
REG0077 experimental Atu4335 (Fha/TagH) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1467064..1468263 (-) 499280697 Unknown (↓)
REG0078 experimental Atu4330 (PpkA) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1458366..1459271 (-) 737274050 Unknown (↓)
REG0079 experimental Atu4331 (TagF-PppA) T6SS00016 experimental protein Tpp Agrobacterium fabrum str C58 chromosome (NC_003063) 1459258..1460673 (-) 159186120 Fha (Atu4335) (↑)
REG0080 experimental Atu2091 T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003063) 2054055..2054864 (-) 159185045 the levels of c-di-GMP (↑)
REG0081 experimental Atu5372 T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003064) 363293..364387 (+) 1805892863 the levels of c-di-GMP (↑)
REG0082 experimental Atu1257 (DgcA) T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 1244567..1245814 (-) 159184686 the levels of c-di-GMP (↑)
REG0083 experimental Atu2179 (DgcC) T6SS00016 experimental protein c-di-GMP regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 2154605..2155744 (-) 159185090 the levels of c-di-GMP (↑)
REG0084 experimental chvG T6SS00016 experimental protein TCS-HK Agrobacterium fabrum str C58 chromosome (NC_003062) 34679..36469 (-) chvI (↓)
REG0085 experimental chvI T6SS00016 experimental protein TCS-RR Agrobacterium fabrum str C58 chromosome (NC_003062) 36525..37250 (-) The intergenic region of the imp and hcp operons (↓)
REG0086 experimental exoR T6SS00016 experimental protein TCS regulatory pathway Agrobacterium fabrum str C58 chromosome (NC_003062) 1702398..1703192 (-) chvG (↑)
REG0087 experimental STM1751 (H-NS) T6SS00023 experimental protein Global regulator Salmonella enterica subsp enterica serovar Typhimurium str LT2 chromosome (NC_003197) 1847277..1847690 (+) 16765095 STM0272 (ClpV) promotor (↑); STM0279 (hcp) promotor (↑); STM0285 promotor (↑); STM0289 (VgrG) promotor (↑); STM0268 promotor (↑)
REG0088 experimental STM0693 (Fur) T6SS00023 experimental protein Global regulator Salmonella enterica subsp enterica serovar Typhimurium str LT2 chromosome (NC_003197) 756397..756849 (-) 16764063 STM0272 (ClpV) promoter (↑)
REG0089 experimental xac4129 (ecfK/RpoE,ECF σ factor) T6SS00028 insolico protein Unknown Xanthomonas citri pv citri str 306 chromosome (NC_003919) 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental xac4127 (PknS) T6SS00028 insolico protein Unknown Xanthomonas citri pv citri str 306 chromosome (NC_003919) 4846892..4849411 (-) 505284326 Unknown (↓)
REG0091 experimental PFL_RS17995 (gacA/uvrY/SirA) T6SS00035 experimental protein TCS-RR Pseudomonas protegens Pf-5 chromosome (NC_004129) 4110513..4111154 (-) 499374263 T6SS transcripts (↓)
REG0092 experimental PFL_RS30815 (pppA) T6SS00035 experimental protein Tpp Pseudomonas protegens Pf-5 chromosome (NC_004129) 6902924..6903658 (-) 499376669 Hcp secretion (↑)
REG0093 experimental ECA_RS00520 (expI) T6SS00040 experimental protein QS regulatory pathway Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 125689..126339 (+) 499404281 T6SS transcripts (ECA4275[hcp1], ECA3428[hcp2] and ECA2866[hcp3]) (↓)
REG0094 experimental ECA3435 (bEBP/VasH) T6SS00040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 3850745..3852298 (-) 499407476 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0095 experimental ECA0288 (rpoN) T6SS00040 experimental protein Global regulator Pectobacterium atrosepticum SCRI1043 chromosome (NC_004547) 336007..337440 (-) 499404454 T6SS gene cluster promoter (PECA3445) (↓); Hcp gene cluster promoter (PECA4275) (↓); Hcp gene cluster promoter (PECA2866) (↓)
REG0096 experimental PSPTO_RS08845 (relA) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 1863879..1866122 (+) 494457621 T6SS transcripts (↓)
REG0097 experimental PSPTO_RS00410 (spoT) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 94805..96910 (-) 492171753 T6SS transcripts (↓)
REG0098 experimental PSPTO_RS04545 (fpRel) T6SS00041 insolico; T6SS00042 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 927082..927900 (+) 499415849 T6SS transcripts (↓)
REG0099 experimental PSPTO_RS28060 (Sfa) T6SS00041 insolico; T6SS00042 experimental protein Global regulator Pseudomonas syringae pv tomato str DC3000 chromosome (NC_004578) 6165047..6166564 (-) 499418021 T6SS transcripts (↓)
REG0100 experimental VP_RS12495 (barA) T6SS00043 experimental; T6SS00044 experimental protein TCS-HK Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2712492..2715290 (+) 491625032 Hcp expression and secretion (↓)
REG0101 experimental VP_RS09470 (UvrY) T6SS00043 experimental; T6SS00044 experimental protein TCS-RR Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2037468..2038112 (-) 491529158 CsrB (↓)
REG0102 experimental VP_RS12395 (CsrA) T6SS00043 experimental; T6SS00044 experimental protein carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2688313..2688510 (-) 490550575 Hcp and vgrG expression and secretion (↓)
REG0103 experimental CsrB1 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 243728..2439035 (+) - VP_RS12395 (CsrA) (↑)
REG0104 experimental CsrB2 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 3215766..3216162 (-) - VP_RS12395 (CsrA) (↑)
REG0105 experimental CsrB3 T6SS00043 experimental; T6SS00044 experimental ncRNA carbon storage regulatory pathway Bacillus megaterium QM B1551 plasmid (NC_004604) 171473..171785 (+) - VP_RS12395 (CsrA) (↑)
REG0106 experimental vp2049 (Thymidylate kinase,Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0107 experimental VP1028 (TfoY) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1077946..1078536 (-) 28897802 T6SS1 (VgrG1) expression and secretion (↓)
REG0108 experimental vp1391 T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1491226..1492857 (-) 28898165 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental vp1407 T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0110 experimental VP1133 (hns) T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1189718..1190125 (-) 28897907 VP1028 (TfoY) (↑)
REG0111 experimental VP2762 (AphA) T6SS00043 experimental; T6SS00044 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2929909..2930448 (+) 28899536 T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112 experimental VP2516 (opaR) T6SS00043 experimental protein QS regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2653215..2653829 (+) 28899290 vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑)
REG0114 experimental VP0820 (ToxR) T6SS00043 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 847892..848770 (-) 28897594 VP1400 promotor (↑); VP1409 promotor (↑)
REG0115 experimental VP0350 (CalR/LeuO) T6SS00044 experimental protein Transcription regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 344763..345722 (+) 28897124 VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0116 experimental VPA1088 (cdpA) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004605) 1147728..1150091 (+) 28900943 VP1028 (TfoY) (↑)
REG0117 experimental VPA0739 (vdcA) T6SS00043 experimental protein c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004605) 772439..773809 (+) 28900594 VP1028 (TfoY) (↓)
REG0118 experimental VP2516 (OpaR) T6SS00043 experimental protein Global regulator Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2653215..2653829 (+) 28899290 T6SS1 (↓)
REG0119 experimental VP1241 (TfoX) T6SS00044 experimental; T6SS00043 experimental protein QS regulatory pathway; c-di-GMP regulatory pathway Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1309223..1309810 (+) 28898016 T6SS2 (↓); T6SS1 (↓)
REG0120 experimental CV_RS20220 (CviR) T6SS00049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 chromosome (NC_005085) 4426186..4427046 (+) 1169634970 CV_RS06990 (VgrG) promotor (↓)
REG0121 experimental CV_RS23145 (CviI) T6SS00049 insolico protein QS regulatory pathway Chromobacterium violaceum ATCC 12472 chromosome (NC_005085) 4426967..4427620 (-) 499450174 CV_RS20220 (CviR) (↓)
REG0122 experimental VF2177 (LitR) T6SS00084 experimental protein QS regulatory pathway Aliivibrio fischeri ES114 chromosome (NC_006840) 2446537..2447142 (+) 59712784 Unknown (↓)
REG0123 experimental VF0896 (TfoX) T6SS00084 experimental protein Global regulator Aliivibrio fischeri ES114 chromosome (NC_006840) 986000..986629 (+) 59711503 T6SS transcripts (↓)
REG0124 experimental VFFQA001_02105 (rpoN) T6SS01277 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 chromosome (NZ_SJSX01000002) 62995..64464 (-) 501526930 hcp1/hcp transcript (↓)
REG0125 experimental VFFQA001_15620 (VasH) T6SS01278 experimental protein Global regulator Aliivibrio fischeri strain FQ-A001 chromosome (NZ_SJSX01000004) 359608..360108 (+) 1027725198 Unknown (↓)
REG0126 experimental BMAA1517 T6SS00070 experimental protein Transcription regulator Burkholderia mallei ATCC 23344 chromosome (NC_006349) 1646532..1647593 (-) 499517952 Hcp1 (BMAA0742) expression (↓)
REG0127 experimental BMAA0746 (VirG) T6SS00070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 chromosome (NC_006349) 764773..765510 (+) 490311617 Hcp1 (BMAA0742) expression (↓)
REG0128 experimental BMAA0745 (VirA) T6SS00070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 chromosome (NC_006349) 762932..764776 (+) 490305845 Hcp1 (BMAA0742) expression (↓)
REG0129 experimental BMAA0746 (VirG) T6SS00070 experimental protein TCS-RR Burkholderia mallei ATCC 23344 chromosome (NC_006349) 764773..765510 (+) 53717366 BMAA0742 (Hcp1) expression (↓); BMAA0729.1 (TssM1) expression (↓)
REG0130 experimental BMAA0745 (VirA) T6SS00070 experimental protein TCS-HK Burkholderia mallei ATCC 23344 chromosome (NC_006349) 763148..764776 (+) 53717365 BMAA0746 (VirG) (↓)
REG0131 experimental BPSL3431 (TctR) T6SS00074 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental BPSL2246 (PpiB) T6SS00076 insolico; T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental BPSS1504 T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006351) 2052905..2055547 (+) 499518990 hcp1 secretion
REG0134 experimental BPSS1546 (BsaN) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2100565..2101230 (-) 490660320 BPSS1495 (virA) promotor (↓)
REG0135 experimental BPS_RS27070 (bicA) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2087441..2087956 (-) 490293043 BPSS 1495(virA) (↓)
REG0136 experimental BPS_RS27175 (bprP) T6SS00077 insolico protein BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2105881..2106081 (+) 490293055 BPSS1546 (BsaN) (↓)
REG0137 experimental BPSS1495 (virA) T6SS00077 insolico protein TCS-RR; BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2038711..2040555 (-) 499518988 T6SS-1 transpript (↓)
REG0138 experimental BPSS1494 (virG) T6SS00077 insolico protein TCS-HK; BsaN regulon Burkholderia pseudomallei K96243 chromosome (NC_006351) 2037977..2038714 (-) 490663798 BPSS1495 (virA) (↓)
REG0139 experimental BPSL1105 (bprP) T6SS00077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 chromosome (NC_006350) 1275668..1276300 (+) 490290369 tssA expression (↓)
REG0140 experimental bprp - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (HM447214) 175..1146 (+) 298239796 tssA expression (↓)
REG0141 experimental bsaN - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (-) - - tssA expression (↓)
REG0142 experimental bspR - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (HM358865) 258..890 (+) 298239780 tssA expression (↓)
REG0143 experimental bprc - protein bspR-dependent signalling cascade Burkholderia pseudomallei strain KHW chromosome (-) - - tssA expression (↓)
REG0144 experimental BPSS1520 (bprC) T6SS00077 insolico protein bspR-dependent signalling cascade Burkholderia pseudomallei K96243 chromosome (NC_006351) 2072125..2073186 (-) 499518995 tssA expression (↓)
REG0145 experimental BPSS1495 (virA) T6SS00077 insolico protein TCS-HK Burkholderia pseudomallei K96243 chromosome (NC_006351) 2038711..2040555 (-) 53722517 hcp1 expression (↓)
REG0146 experimental BPSS1494 (virG) T6SS00077 insolico protein TCS-RR Burkholderia pseudomallei K96243 chromosome (NC_006351) 2037977..2038714 (-) 53722516 hcp1 expression (↓)
REG0147 experimental FTT1557c/FNU0663.2 (pmrA) T6SS00081 experimental protein TCS-RR Francisella tularensis subsp tularensis SCHU S4 chromosome (NC_006570) 1618742..1619428 (-) 489108239 T6SS transcription (↓)
REG0148 experimental PSYR_RS19090 (relA) T6SS00086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 4380642..4382885 (-) 499587809 T6SS transcripts (↓)
REG0149 experimental PSYR_RS01070 (spoT) T6SS00086 experimental protein (p)ppGpp regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 223004..225109 (-) 489499092 T6SS transcripts (↓)
REG0150 experimental Psyr_3698 (gacS) T6SS00086 experimental protein TCS-HK Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 4385550..4388303 (+) 499587812 T6SS transcription (↓)
REG0151 experimental Psyr_4339 (ladS) T6SS00086 experimental protein QS regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 5191591..5193585 (-) 639463044 T6SS transcription (↓)
REG0152 experimental Psyr_4408 (retS) T6SS00086 experimental protein QS regulatory pathway Pseudomonas syringae pv syringae B728a chromosome (NC_007005) 5270882..5273671 (+) 489494774 T6SS transcription (↑)
REG0153 experimental BTH_I1281 (OxyR) T6SS00113 experimental protein Global regulator Burkholderia thailandensis E264 chromosome (NC_007651) 1432632..1433591 (+) 497575020 BTH_RS09735 (T6SS-4) Promotor,−536 to −186 relative to the ATG start codon (↑)
REG0154 experimental bth_I0691 (Zur) T6SS00113 experimental protein Global regulator Burkholderia thailandensis E264 chromosome (NC_007651) 796074..796538 (-) 497578547 BTH_RS09735 (T6SS-4) Promotor,−541 to −1 relative to the ATG start codon (↑)
REG0155 experimental BTH_II1510 (BtaR1) T6SS00115 experimental protein QS regulatory pathway Burkholderia thailandensis E264 chromosome (NC_007650) 1779070..1779789 (-) 497583165 BTH_I2691/BTH_I2693-99/BTH_I2701-702 (↓)
REG0156 experimental pvfC T6SS00125 insolico protein Global regulator Pseudomonas entomophila L48 chromosome (NC_008027) - - T6SS secreted proteome (↓)
REG0157 experimental rmsF T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PA103 chromosome (NZ_JARI00000000) - - tssA1 RNA (↑); RsmY/Z (↑)
REG0158 experimental PA14_52570 (RsmA) T6SS00150 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4660393..4660578 (-) 489176459 RSMF (↑); tssA1 RNA (↑); RSMA (↑)
REG0159 experimental PA14_RS20260/PA1120 (YfiN/TpbB) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4435431..4436738 (-) 489207392 Hcp1 production (↓)
REG0160 experimental PA14_RS15060 (PA2133 phosphodiesterase) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 3294000..3294857 (-) 489200657 Hcp1 production (↑)
REG0161 experimental PA14_RS06615 (WspR) T6SS00150 experimental protein c-di-GMP regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1413158..1414201 (+) 489183089 Hcp1 production (↓)
REG0162 experimental RsmY T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 596840..596963 (+) Unknown
REG0163 experimental RsmZ T6SS00150 experimental ncRNA RsmA regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1500352..1500467 (+) Unknown
REG0164 experimental PA14_RS05020 (LadS) T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1069280..1071716 (+) 15599169 Unknown
REG0165 experimental PA14_64230/PA4856 (RetS) T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 5722815..5725643 (+) 489202068 Unknown
REG0166 experimental PA14_45960 (lasR) T6SS00152 experimental; T6SS00151 experimental; T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4085339..4086058 (-) 489173455 TssA2 (PA14_43050) promotor (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0167 experimental PA14_51340 (MvfR) T6SS00152 experimental; T6SS00151 experimental; T6SS00150 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4562837..4563835 (+) 489176730 Upstream of pqs operon (↓); HSI-III transcripts (↓); HSI-I transcripts (↑)
REG0168 experimental PA14_51380 (pqsE) T6SS00150 experimental; T6SS00152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4566077..4566982 (-) 489176725 T6SS Transciption (↓)
REG0169 experimental PA14_22470 (PA3225) T6SS00150 experimental; T6SS00152 experimental; T6SS00151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1955624..1956553 (-) 489182081 PA14_00990 (TssA) promotor (↓); TssA1 (PA14_00990) transcript (↑); TssA2 (PA14_43050) transcript (↑); TssB3 (PA14_34070) transcript (↑)
REG0170 experimental PA14_20290 (AmrZ) T6SS00150 experimental; T6SS00152 experimental; T6SS00151 experimental protein Global regulator Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 1747602..1747928 (-) 489182353 TssA1 (PA14_00990) promotor (↓); TssA2 (PA14_43050) promotor (↑); TssB3 (PA14_34070) promotor (↓)
REG0171 experimental APECO1_487 (FNR) T6SS00155 insolico protein Global regulator Escherichia coli APEC O1 chromosome (NC_008563) 1455411..1456163 (-) 446534565 APECO1_1756 (VgrG1) (↓)
REG0172 experimental PA14_48150 (QslA) T6SS00152 experimental protein QS regulatory pathway Pseudomonas aeruginosa UCBPP-PA14 chromosome (NC_008463) 4286222..4286536 (+) 489177206 H2-T6SS (PA14_43050) promotor (↑)
REG0173 experimental FTN_RS06610 (mglA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1362282..1362899 (+) 489124662 iglC transcription (↓); Unknown (↓)
REG0174 experimental FTN_RS02845 (SspA) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 574840..575472 (+) 500053699 FTN_1465 (pmrA) (↓)
REG0175 experimental FTN_RS08805 (KdpD) T6SS00158 experimental protein TCS-HK Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1838601..1841282 (-) 489131611 FTN_1465 (pmrA) (↓)
REG0176 experimental FTN_1465 (pmrA) T6SS00158 experimental protein TCS-RR; TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1553358..1554044 (-) 489108239 FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimental FTN_RS06615 (mglB) T6SS00158 experimental protein Global regulator; TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 1362901..1363308 (+) 489112095 IglA expression (↓); T6SS Transciption (↓)
REG0178 experimental FTN_0480 (fevR/PigR) T6SS00158 experimental protein TCS regulatory pathway Francisella tularensis subsp novicida U112 chromosome (NC_008601) 486541..486876 (+) 489108070 T6SS Transciption (↓)
REG0179 experimental A1S_0268 (hns) T6SS01000 insolico protein Global regulator Acinetobacter baumannii ATCC 17978 chromosome (CP000521) 292215..292541 (+) - A1S_1292 Transcript (↑)
REG0180 experimental VC0395_RS17530 (TsrA) T6SS00208 insolico; T6SS00487 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009457) 2598392..2598676 (-) 445982516 T6SS Transciption (↑)
REG0181 experimental VC0395_0020/VCA0117 (bEBP/vasH) T6SS00208 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009456) 22315..23907 (-) 446006938 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓)
REG0182 experimental VC0395_A2109 (rpoN) T6SS00208 insolico protein Global regulator Vibrio cholerae O395 chromosome (NC_009457) 2265078..2266541 (+) 446727517 T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓); hcp promoter (PVCA0017/VC0395_0116) (↓)
REG0183 experimental Mmwyl1_1758 (bEBP/vasH) T6SS00216 insolico protein Global regulator Marinomonas sp MWYL1 chromosome (NC_009654) 1985170..1986666 (+) 501016781 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0184 experimental Mmwyl1_2418 (RpoN) T6SS00216 insolico protein Global regulator Marinomonas sp MWYL1 chromosome (NC_009654) 2725212..2726687 (+) 501017436 T6SS gene cluster promoter (PMWYL1196/PMWYL1195) (↓)
REG0185 experimental YpsIP31758_3980 (ompR) T6SS00225 experimental protein TCS-RR Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 4465260..4465979 (-) 490527984 T6SS-4 promoter (↓)
REG0186 experimental YpsIP31758_3441 (lptD) T6SS00225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0187 experimental YPK_3449 (RelA) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3783755..3785989 (-) 488138165 YPK_1551 (RovM) (↓); YPK_1876 (RovA) (↓)
REG0188 experimental YPK_1876 (RovA) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 2082384..2082815 (+) 488139747 T6SS-4 promoter region (↓); T6SS-4 promoter region (↓)
REG0189 experimental YPK_4079 (OxyR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 4502978..4503895 (-) 488138270 T6SS-4 promoter region (↓)
REG0190 experimental ypk_3425 (RpoS) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3759239..3760237 (-) 499505140 T6SS-4 promoter region (↓)
REG0191 experimental YPK_1551 (RovM) T6SS00260 experimental protein (p)ppGpp regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1713682..1714884 (-) 499506038 T6SS-4 promoter region (↓)
REG0192 experimental YPK_3567 (RovC) T6SS00260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3929654..3930397 (+) 170025782 YPK_3567 promotor (↓)
REG0193 experimental YPK_3372 (CsrA) T6SS00260 experimental protein carbon storage regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 3698608..3698793 (-) 169752121 YPK_3567 (RovC) (↑); YPK_3563 transcript (↑)
REG0194 experimental YPK_2462 (HpaR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 2695107..2695574 (+) 169751221 T6SS4 promoter (↓)
REG0195 experimental YPK_RS08345 (YpsR) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1837676..1838413 (+) 488140651 T6SS transcripts (↓)
REG0196 experimental YPK_RS03965 (YtbR) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 900476..901219 (+) 488140447 T6SS transcripts (↓)
REG0197 experimental YPK_RS08350 (ypsI) T6SS00256 insolico protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 1838406..1839050 (-) 501053391 T6SS transcripts (↓)
REG0198 experimental YPK_RS03970 (ytbI) T6SS00256 insolico; T6SS00260 experimental protein QS regulatory pathway Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 901200..901850 (-) 488144695 T6SS transcripts (↓); T6SS4 transcripts and hcp secretion (↓)
REG0199 experimental YPK_RS00840 (OmpR) T6SS00260 experimental protein TCS-RR Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 223260..223979 (+) 488137706 T6SS4 promoter (↓)
REG0200 experimental YPK_RS01520 (ZntR) T6SS00260 experimental protein Global regulator Yersinia pseudotuberculosis YPIII chromosome (NC_010465) 333471..333896 (+) 488144494 T6SS4 promoter (↓)
REG0201 experimental PMI0271 (MrpJ) T6SS00272 experimental protein Global regulator Proteus mirabilis HI4320 chromosome (NC_010554) 318458..318781 (+) 490365253 PMI0749 (tssA); PMI2990 (idsA/hcp)
REG0202 experimental PXO_RS20535 T6SS00287 experimental protein Unknown Xanthomonas oryzae pv oryzae PXO99A chromosome (NC_010717) 4488457..4488843 (-) 499576999 Unknown (↓)
REG0203 experimental KP1_3314 (hns) T6SS00344 experimental protein Global regulator Klebsiella pneumoniae subsp pneumoniae NTUH-K2044 chromosome (NC_012731) 3140175..3140582 (+) 238895262 KP1_2392 (TssB) promotor (↑); KP1_2392 (hcp) (↑)
REG0204 experimental NT01EI_RS04325 (EsrB) T6SS00346 experimental protein TCS-RR Edwardsiella ictaluri 93-146 chromosome (NC_012779) 955101..955745 (-) 506350644 T6SS translocon protein EvpC secretion (↓)
REG0205 experimental NT01EI_RS04200 (EsrC) T6SS00346 experimental protein TCS regulatory pathway Edwardsiella ictaluri 93-146 chromosome (NC_012779) 933326..934018 (-) 737638726 T6SS translocon protein EvpC secretion (↓)
REG0206 experimental ETAE_2873 (RpoS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3025094..3026080 (-) 502612732 ETAE_0886 (esrB) promoter (↑)
REG0207 experimental ETAE_0035 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 35881..37008 (+) 502609898 ETAE_0886 (esrB) promoter (↑)
REG0208 experimental ETAE_0154 (hemB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 159867..160889 (+) 502610017 ETAE_0886 (esrB) promoter (↑)
REG0209 experimental ETAE_0743 (cdsA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 820052..820909 (+) 502610607 ETAE_0886 (esrB) promoter (↑)
REG0210 experimental ETAE_2082 (pyrF) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2196136..2196858 (-) 502611934 ETAE_0886 (esrB) promoter (↑)
REG0211 experimental ETAE_1096 (dapA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1194778..1195659 (+) 502610962 ETAE_0886 (esrB) promoter (↑)
REG0212 experimental ETAE_2697 (cysS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2831230..2832615 (-) 502612557 ETAE_0886 (esrB) promoter (↑)
REG0213 experimental ETAE_1760 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1870377..1870535 (+) 267984768 ETAE_0886 (esrB) promoter (↑)
REG0214 experimental ETAE_1837 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1946159..1946284 (-) 267984845 ETAE_0886 (esrB) promoter (↑)
REG0215 experimental ETAE_1202 (ugd) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1306603..1307769 (+) 502611067 ETAE_0886 (esrB) promoter (↑)
REG0216 experimental ETAE_2640 (holA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2779832..2780866 (+) 502612494 ETAE_0886 (esrB) promoter (↑)
REG0217 experimental ETAE_1439 (ruvA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1550776..1551384 (+) 502611302 ETAE_0886 (esrB) promoter (↑)
REG0218 experimental ETAE_0358 (purA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 403538..404836 (+) 502610221 ETAE_0886 (esrB) promoter (↑)
REG0219 experimental ETAE_2813 (iscA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2952011..2952334 (-) 491431780 ETAE_0886 (esrB) promoter (↑)
REG0220 experimental ETAE_2787 (guaB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2925310..2926776 (-) 502612646 ETAE_0886 (esrB) promoter (↑)
REG0221 experimental ETAE_1412 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1522924..1523409 (-) 502611274 ETAE_0886 (esrB) promoter (↑)
REG0222 experimental ETAE_0430 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 473075..473755 (-) 502610291 ETAE_0886 (esrB) promoter (↑)
REG0223 experimental ETAE_0659 (aceE) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 731608..734271 (+) 502610523 ETAE_0886 (esrB) promoter (↑)
REG0224 experimental ETAE_2773 (mtnN) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2910743..2911441 (+) 502612632 ETAE_0886 (esrB) promoter (↑)
REG0225 experimental ETAE_2468 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2598484..2599356 (-) 504339400 ETAE_0886 (esrB) promoter (↑)
REG0226 experimental ETAE_1614 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1721332..1722024 (-) 754045576 ETAE_0886 (esrB) promoter (↑)
REG0227 experimental ETAE_0994 (Lon) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1085063..1087288 (+) 267984010 ETAE_0886 (esrB) promoter (↓)
REG0228 experimental ETAE_3542 (phoU) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3747537..3748268 (+) 502613380 ETAE_0886 (esrB) promoter (↓)
REG0229 experimental ETAE_3449 (tpiA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3637381..3638145 (+) 502613286 ETAE_0886 (esrB) promoter (↓)
REG0230 experimental ETAE_1655 (prc) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1757898..1759940 (+) 735677771 ETAE_0886 (esrB) promoter (↓)
REG0231 experimental ETAE_1158 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1257412..1258584 (+) 502611022 ETAE_0886 (esrB) promoter (↓)
REG0232 experimental ETAE_0772 (tadA) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 850367..850879 (+) 505698653 ETAE_0886 (esrB) promoter (↓)
REG0233 experimental ETAE_0695 (mrcB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 766885..769368 (+) 502610560 ETAE_0886 (esrB) promoter (↓)
REG0234 experimental ETAE_1170 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (CP001135) 1271304..1271447 (-) 267984186 ETAE_0886 (esrB) promoter (↓)
REG0235 experimental ETAE_1562 T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1668753..1670378 (-) 780104675 ETAE_0886 (esrB) promoter (↓)
REG0236 experimental ETAE_3453 (cpxR) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3641204..3641902 (+) 502613290 ETAE_0886 (esrB) promoter (↓)
REG0237 experimental ETAE_0263 (mltC) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 293215..294306 (-) 1392602598 ETAE_0886 (esrB) promoter (↓)
REG0238 experimental ETAE_0542 (slt) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 588958..590886 (+) 502610404 ETAE_0886 (esrB) promoter (↓)
REG0239 experimental ETAE_2638 (leuS) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 2776570..2779152 (+) 502612492 ETAE_0886 (esrB) promoter (↓)
REG0240 experimental ETAE_3207 (rplQ) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3390207..3390593 (-) 491439763 ETAE_0886 (esrB) promoter (↓)
REG0241 experimental ETAE_1010 (acrB) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1099309..1102461 (-) 502610875 ETAE_0886 (esrB) promoter (↓)
REG0242 experimental ETAE_1425 (mviN) T6SS00372 experimental protein TCS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 1535368..1536906 (+) 502611288 ETAE_0886 (esrB) promoter (↓)
REG0243 experimental ETAE_0886 (EsrB) T6SS00372 experimental protein TCS-RR Edwardsiella tarda EIB202 chromosome (NC_013508) 964658..965302 (-) 502610749 Unknown (↓); Unknown (↓)
REG0244 experimental ETAE_2059 (phoP) T6SS00372 experimental protein TCS-HK Edwardsiella tarda EIB202 chromosome (NC_013508) 2172565..2173239 (+) 502611910 ETAE_0886 (EsrB) (↓)
REG0245 experimental ETAE_3098 (PepA) T6SS00372 experimental protein Transcription regulator Edwardsiella tarda EIB202 chromosome (NC_013508) 3260322..3261833 (+) 502612947 ETAE_0886 (esrB) promoter (↑)
REG0246 experimental ETAE_3474 (fabR) T6SS00372 experimental protein QS regulatory pathway Edwardsiella tarda EIB202 chromosome (NC_013508) 3666488..3667159 (-) 502613311 Unknown (↓)
REG0247 experimental ETAE_1505 (H-NS) T6SS00372 experimental protein Transcription regulator Edwardsiella tarda EIB202 chromosome (NC_013508) 1615099..1615506 (-) 505274277 ETAE_2430 (evpB) (↑); evpC promotor (↑)
REG0248 experimental EC042_RS26480 (aggR) T6SS00464 experimental protein Transcription regulator Escherichia coli 042 plasmid (NC_017627) 41080..41877 (-) 446692110 EC042_RS26480 (aggR) promoter (↓); EC042_RS26480 (aggR) promoter (↓)
REG0249 experimental EC042_RS18855 (FIS) T6SS00464 experimental protein Transcription regulator Escherichia coli 042 chromosome (NC_017626) 3772795..3773091 (+) 446385050 EC042_RS26480 (aggR) promoter (↓)
REG0250 experimental EC042_RS06800 (Hns) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 1376831..1377244 (-) 447210122 EC042_RS26480 (aggR) promoter (↑)
REG0251 experimental EC042_RS03685 (Fur) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 786918..787364 (-) 446053847 EC042_4532 promoter (↑); EC042_4524 (TssB) promotor (↑)
REG0252 experimental EC042_RS19435 (Dam) T6SS00464 experimental protein Global regulator Escherichia coli 042 chromosome (NC_017626) 3861171..3862007 (-) 446664793 EC042_4532 promoter (↑)
REG0253 experimental PAM18_RS12360 (gacA) T6SS00612 insolico; T6SS00613 insolico; T6SS00611 insolico protein TCS-RR Pseudomonas aeruginosa M18 chromosome (NC_017548) 2625815..2626459 (+) 489180874 hsiA1 operon transcript (↓); hsiA2 operon transcript (↓); hsiA3 operon transcript (↓)
REG0254 experimental VasH T6SS00788 experimental protein Transcription regulator Aeromonas hydrophila strain SSU chromosome (DQ667172) 15458..16996 (+) 110277136 hcp expression (↓)
REG0255 experimental ahyI T6SS00788 experimental protein QS regulatory pathway Aeromonas hydrophila strain SSU chromosome (DQ398101) 843..1466 (+) 89027174 ahyR (↓)
REG0256 experimental ahyR T6SS00788 experimental protein QS regulatory pathway Aeromonas hydrophila strain SSU chromosome (DQ398101) 1..783 (-) 89027173 hcp and vgrG2 expression (↓)
REG0257 experimental VEPGS_0614 (PppA) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 15765..16880 (+) 225382180 LuxR (↓)
REG0258 experimental VEPGS_0606 (PpkA2) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 3227..5377 (-) 225382172 LuxR (↓); VEPGS_0610 (DotU2) (↓)
REG0259 experimental VEPGS_0607 (Fha2) T6SS00794 experimental protein Tpp Vibrio alginolyticus strain EPJS chromosome (FJ790777) 5690..6775 (+) 225382173 VEPGS_0610 (DotU2) (↓)
REG0260 experimental EPGS_00471 (VtsR) T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - LuxO (↓)
REG0261 experimental EPGS_00471 (VtsR) T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - LuxO (↑)
REG0262 experimental luxR T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - T6SS2 transcript and expression (↓)
REG0263 experimental luxR T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript and expression (↑)
REG0264 experimental VEPGS_0621 (pppA) T6SS00793 experimental protein Tpp; QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) 23577..24245 (+) 225382187 Unknown (↑); T6SS1 transcript (↑); hcp1 transcript (↓)
REG0265 experimental luxS T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - hcp1 transcript (↓)
REG0266 experimental LuxO T6SS00793 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - hcp1 transcript (↓)
REG0267 experimental LuxO T6SS00794 experimental protein QS regulatory pathway Vibrio alginolyticus strain EPJS chromosome (FJ790777) - - Unknown (↑)
REG0268 experimental rpoN T6SS00793 experimental protein Transcription regulator Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript (↓)
REG0269 experimental VasH T6SS00793 experimental protein Transcription regulator Vibrio alginolyticus strain EPJS chromosome (FJ790776) - - T6SS1 transcript (↓)
REG0270 experimental CXG97_03740 (Fur) T6SS00904 experimental protein Transcription regulator Escherichia coli strain ExPEC XM chromosome (NZ_CP025328) 729474..729920 (-) 446053847 T6SS1 (TssB) promotor (↑)
REG0271 experimental H1D38_08255 (fur) T6SS00931 experimental protein Global regulator Escherichia coli strain 17-2 chromosome (JACEFV010000001) 1744748..1745194 (-) MBA2233871.1 sciH promotor (↑)
REG0272 experimental H1D38_12840 (Dam) T6SS00931 experimental protein Global regulator Escherichia coli strain 17-2 chromosome (JACEFV010000002) 105877..106713 (+) MBA2234741.1 sciH promotor (↑)
REG0273 experimental W817_21870 (CpxR) T6SS00937 experimental protein TCS-RR Escherichia coli RS218 chromosome (NZ_CP007149) 4360812..4361510 (-) 446956464 hcp2B promoter (↓)
REG0274 experimental W817_01610 (NplE) T6SS00937 experimental protein TCS regulatory pathway Escherichia coli RS218 chromosome (NZ_CP007149) 214947..215657 (+) 446161331 W817_RS21690 (CpxA) (↓)
REG0275 experimental V12G01_21538 (LuxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009644 chromosome (AAPS01000053) 13551..14165 (-) 91187814 T6SS2 transcripts (↓)
REG0276 experimental V12G01_19736 (TfoX) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009693 chromosome (AAPS01000019) 47689..48276 (-) 91189146 T6SS2 transcripts (↓)
REG0277 experimental V12G01_20658 (TfoY) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009646 chromosome (AAPS01000015) 63783..64190 (+) 91189474 T6SS transcripts (↓)
REG0278 experimental V12G01_20201 (H-NS) T6SS00939 experimental protein Transcription regulator Vibrio alginolyticus 12G01 1100007009646 chromosome (AAPS01000015) 63783..64190 (+) 91189474 VaT6SS1 transcripts (↑)
REG0279 experimental V12G01-18672 (vqsA) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009692 chromosome (AAPS01000003) 114208..115086 (+) 91191289 V12G01-21538 (luxR) promoter (↓); V12G01-14830 (aphA) promoter (↓); V12G01-18672 (vqsA) promotor (↓)
REG0280 experimental V12G01_10813 (AsnC) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0281 experimental V12G01_02325 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 115263..116411 (+) 91190993 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0282 experimental V12G01_01665 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009655 chromosome (AAPS01000007) 185299..185712 (+) 91190406 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0283 experimental V12G01_06711 (HP) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009529 chromosome (AAPS01000024) 47707..48585 (-) 91188835 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0284 experimental V12G01_16177 (MetR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009686 chromosome (AAPS01000023) 58420..59331 (-) 91188901 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0285 experimental V12G01_02620 (SoxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009656 chromosome (AAPS01000004) 181050..181484 (-) 91191052 V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0286 experimental V12G01_21538 (luxR) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009644 chromosome (AAPS01000053) 13551..14165 (-) 91187814 V12G01-18672 (vqsA) promotor
REG0287 experimental V12G01-14830 (aphA) T6SS00939 experimental protein QS regulatory pathway Vibrio alginolyticus 12G01 1100007009682 chromosome (AAPS01000027) 42305..42880 (+) 91188695 V12G01-18672 (vqsA) promotor
REG0288 experimental VCA1552_03277/VCA0566 (VxrB) T6SS00002 experimental protein TCS-RR Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 504728..505384 (+) 446737785 Unknown (↑)
REG0289 experimental VCA0933 (CspV) T6SS00002 experimental protein c-di-GMP regulatory pathway Vibrio cholerae O1 biovar El Tor str N16961 chromosome (NC_002506) 886068..886280 (+) 446027150 Unknown (↓)
REG0290 experimental VCA1552_01380 (VdcA/ycdT) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1482426..1483715 (+) 446892247 the levels of c-di-GMP (↑)
REG0291 experimental VCA1552_02536 (CdpA/YfgF) T6SS01112 experimental protein c-di-GMP regulatory pathway Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 2739669..2742158 (-) 446417730 the levels of c-di-GMP (↓)
REG0292 experimental VCA1552_02898 (VasH) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024868) 128889..130481 (+) 446006938 VCA1552_00900 (TfoX) (↓)
REG0293 experimental VCA1552_00351 (HapR) T6SS01112 experimental protein Global regulator Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 340447..341058 (-) 446262243 Unknown; Hcp expression and secretion
REG0294 experimental VCA1552_RS04890 (ihfA) T6SS01112 experimental protein Transcription regulator Vibrio cholerae