Pseudomonas aeruginosa PAO1



Accession: NC_002516
 


experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0018 experimental PA4462 (RpoN) T6SS00003 experimental; T6SS00004 experimental; T6SS00005 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 PA1512 (hcpA) promotor (↓); PA5267 (hcpB) promotor (↓)
REG0040 experimental PA0592 (RsmA) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 650575..651381 (-) 15595789 FHA (PA0081) (↑)
REG0041 experimental PA5183a (RsmN) T6SS00003 experimental protein RsmA regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5836470..5836685 (-) 554753081 FHA (PA0081) (↑); PA3487 (pldA) expression (↑)
REG0042 experimental PA0075 (PppA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90106..90834 (-) 15595273 PA0081 (Fha-1/TagH) (↑)
REG0043 experimental PA0074 (PpkA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 87000..90098 (-) 15595272 PA0081 (Fha-1/TagH) (↓)
REG0044 experimental PA2586 (gacA) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2925788..2926432 (-) 15597782 hcp1 (PA0085) expression and secretion (↓)
REG0045 experimental PA0610 (prtN) T6SS00003 experimental protein TCS-HK Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 672777..673091 (-) 15595807 PA0611 (prtR) (↑)
REG0046 experimental PA0611 (prtR) T6SS00003 experimental protein TCS-RR Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 673191..673961 (-) 15595808 hcp1 (PA0085) expression and secretion (↑); PA2586 (gacA) (↑)
REG0047 experimental PA0072 (TagS) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 85085..86284 (-) 15595270 PA0073 (TagT) (↓)
REG0048 experimental PA0070 (TagQ) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 82404..83318 (-) 15595268 PA0071 (tagR) (↓)
REG0049 experimental PA0073 (TagT) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 86284..87003 (-) 15595271 PA0072 (TagS) (↓)
REG0050 experimental PA2492 (MexT) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental PA1006 T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0052 experimental PA0071 (tagR) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 83380..85092 (-) 15595269 PA0074 (PpkA) (↓)
REG0053 experimental PA4856 (RetS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5452150..5454978 (+) 15600049 hcp1 (PA0085) expression and secretion (↑)
REG0054 experimental PA3974 (LadS) T6SS00003 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4453289..4455676 (-) 15599169 hcp1 (PA0085) expression and secretion (↓)
REG0055 experimental PA4109 (AmpR) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0056 experimental PA0076 (TagF) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 90844..91524 (-) 15595274 hcp1 (PA0086) secretion (↑)
REG0057 experimental PA0081 (Fha-1/TagH) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 98263..99756 (-) 15595279 Unknown (↓); clpV (↓)
REG0058 experimental PA2976 (RNase E) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0059 experimental PA4704.1 (prrF1) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5283960..5284110 (+) 4179187 T6SS transcripts (↓)
REG0060 experimental PA4704.2 (prrF2) T6SS00003 experimental; T6SS00004 experimental ncRNA QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5284172..5284319 (+) 4179185 T6SS transcripts (↓)
REG0061 experimental PA0996 (pqsA) T6SS00004 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1078462..1080015 (+) 15596193 T6SS transcripts
REG0062 experimental PA1244 (QslA) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1348060..1348401 (-) 15596441 H2-T6SS (PA1656) promotor (↑)
REG0063 experimental PA4778 (CueR) T6SS00004 experimental protein Transcription regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5366257..5366655 (+) 15599972 tssA2 (-173 to -140 relative to the ATG start codon) (↓); hcp2 (-208 to -159 relative to the ATG start codon) (↓)
REG0065 experimental PA1430 (LasR) T6SS00004 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1558171..1558890 (+) 15596627 H2-T6SS promotor P (hsiA2) (↓)
REG0066 experimental PA3476 (rhlI) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889139..3889744 (-) 15598672 PA3477 (RhlR) (↓)
REG0067 experimental PA3477 (RhlR) T6SS00004 experimental protein QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3889925..3890650 (-) 15598673 T6SS transcript (↓)
REG0068 experimental PA4764 (Fur) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5351675..5352079 (-) 15599958 H2-T6SS Transcription (↑)
REG0069 experimental PA4462 (rpoN) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4992870..4994363 (+) 15599658 T6SS transcript (↑)
REG0070 experimental pa1663 (sfa2) T6SS00004 experimental; T6SS00005 experimental protein Global regulator; QS regulatory pathway Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1813395..1814906 (+) 15596860 PA4462 (rpoN) (↑); T6SS transcript (↑); T6SS transcript (↓)
REG0368 experimental PA1544 (Anr) T6SS00004 experimental protein Global regulator Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1681071..1681805 (-) 15596741 H2-T6SS transcriptional level and ModA secretion (↓)
REG0376 experimental PA3648 (bamA) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4085062..4087455 (-) NP_252338.1 ClpV-GFP foci accumulate; H1-T6SS transcript (↑)
REG0377 experimental PA0595 (lptD) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 653753..656527 (-) NP_249286.1 ClpV-GFP foci accumulate; H1-T6SS transcript (↑)
REG0378 experimental PA0972 (tolB) T6SS00003 experimental protein Tpp Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1056049..1057347 (+) NP_249663.1 ClpV-GFP foci accumulate; H1-T6SS transcript (↑)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Effector ID Locus tag (Gene) Classification Cognate immunity protein Related T6SS Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
EFF01496 experimental PA0262 (VgrG2b) Tpe IMU00315 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 293802..296861 (-) 15595459
EFF01466 experimental PA2374 Tie - T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2626221..2626757 (+) 15597570
EFF01823 experimental PA4922 (Azu) Tie - T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5521664..5522110 (-) 15600115
EFF00014 experimental PA1844 (Tse1, Tae1) Tae IMU00190 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2003868..2004332 (-) 15597041
EFF01870 experimental PA0807 (AmpDh3) Tae IMU00360 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 884799..885566 (+) 15596004
EFF01318 experimental PA0099 (Tse7) Tde IMU00333 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 120164..121324 (+) 15595297
EFF01482 experimental PA3907 (TseT) Tde IMU00309 experimental T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4375230..4376015 (+) 15599102
EFF00017 experimental PA3484 (Tse3, Tge1) Tge IMU00191 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3898278..3899504 (+) 15598680
EFF01889 experimental PA1863 (ModA) Tie - T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2022411..2023166 (-) 15597060
EFF00019 experimental PA3487 (Tle5) Tle IMU00080 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3902663..3905962 (+) 15598683
EFF01450 experimental PA0260 Tle IMU00315 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 291154..293304 (-) 15595457
EFF01463 experimental PA1510 Tle IMU00314 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1639791..1641500 (-) 15596707
EFF01279 experimental PA5089 (PldB) Tle IMU00044 experimental; IMU00045 experimental; IMU00046 experimental T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5727239..5729476 (-) 15600282
EFF01891 experimental PA0822 (TseV) Tne IMU00382 experimental T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 898440..898886 (-) -
EFF00016 experimental PA2702 (Tse2) Tse IMU00107 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3056890..3057366 (+) 15597898
EFF01037 experimental PA2774 (Tse4) Tse IMU00274 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3132229..3132816 (-) 15597970
EFF01036 experimental PA2684 (Tse5) Tse - T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3031749..3035702 (-) 15597880
EFF01035 experimental PA0093 (Tse6) Tse IMU00273 experimental T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 113303..114595 (-) 15595291
EFF01892 experimental PA2066 Tse - T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2265126..2265764 (-) 15597262
EFF01893 experimental PA2056 Tse - T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2249693..2250595 (+) 15597252
EFF00009 experimental PA0085 - - T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 103350..103838 (+) 15595283
EFF00010 experimental PA0091 - - T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 110976..112907 (+) 15595289
EFF00011 experimental PA0095 - - T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 115299..117524 (+) 15595293
EFF00015 experimental PA2685 - - T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3035752..3037932 (-) 15597881
EFF00012 experimental PA0263 (hcp2) - - T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 297043..297561 (-) 15595460
EFF76635 experimental PA0824 (PAAR2) - - T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 899138..899656 (-) NP_249515.1

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Immunity protein ID Locus tag (Gene) Related T6SS Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Cognate effector
IMU00044 experimental PA5086 T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5724601..5725242 (-) 15600279 EFF76635 experimental
IMU00045 experimental PA5087 T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5725479..5726348 (-) 15600280 EFF76635 experimental
IMU00046 experimental PA5088 T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5726357..5727238 (-) 15600281 EFF76635 experimental
IMU00080 experimental PA3488 (Tli5) T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3906391..3907089 (+) 15598684 EFF76635 experimental
IMU00107 experimental PA2703 (Tsi2) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3057376..3057609 (+) 15597899 EFF76635 experimental
IMU00190 experimental PA1845 (Tsi1,Tai1) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2004374..2004892 (-) 15597042 EFF76635 experimental
IMU00191 experimental PA3485 (Tsi3,Tgi1) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3899501..3899938 (+) 15598681 EFF76635 experimental
IMU00273 experimental PA0092 (Tsi6) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 113022..113306 (-) 15595290 EFF76635 experimental
IMU00274 experimental PA2775 (Tsi4) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3132821..3133258 (-) 15597971 EFF76635 experimental
IMU00284 experimental PA2684.1 (Tsi5) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) - EFF76635 insolico
IMU00309 experimental PA3908 T6SS00005 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4376012..4376731 (+) 15599103 EFF76635 experimental
IMU00314 experimental PA1509 (TplEi) T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1638652..1639794 (-) 15596706 EFF76635 experimental
IMU00315 experimental PA0261 (Tli3) T6SS00004 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 293301..293798 (-) 15595458 EFF76635 insolico
IMU00333 experimental PA0100 (Tsi7) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 121346..122266 (+) 15595299 EFF76635 experimental
IMU00360 experimental PA0808 T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 885635..886108 (+) 15596005 EFF76635 experimental
IMU00382 experimental PA0821 (TsiV) T6SS00003 experimental Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 897335..898423 (-) 15596018 EFF76635 experimental

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
ID           Locus tag (Gene) Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Response to T6SS attack Known or putative function
RSF000020 experimental PA1326 (ilvA2) Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1437067..1438614 (+) 15596523 protective amino acid biosynthesis
RSF000021 experimental PA4804 Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5388702..5390099 (-) 15599998 protective a putative amino acid permease PA4804
RSF000022 experimental PA0867 (mliC) Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 948776..949159 (+) 15596064 protective a membrane-bound lysozyme inhibitor
RSF000023 experimental PA2824 (sagS) Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3177090..3179450 (+) 15598020 protective a biofilm sensor/regulator
RSF000024 experimental PA3714 Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4160329..4160970 (+) 15598909 protective a putative RcsB-like regulator
RSF000025 experimental PA4739 (osmY) Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 5322757..5323101 (-) 15599933 protective a predicted osmotic stress resistance
RSF000026 experimental PA4410 (ddlB) Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4942677..4943636 (-) 15599606 protective D-alanine--D-alanine ligase

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Accessory protein ID Locus tag (Gene) Related T6SS Type             Organism                 Replicon (Accession) Coordinates (Strand) Protein GI Related structure protein Related effector
ACP00002 experimental PA0094 (eagT6) T6SS00003 experimental adaptor Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 114611..115045 (-) 15595292 - PA0093 (Tse6)
ACP00003 experimental PA0086 (tagJ) T6SS00003 experimental structure affiliated protein Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 104006..104851 (+) 15595284 PA0082 (TssA) -
ACP00004 experimental PA0086 (tagJ) T6SS00003 experimental structure affiliated protein Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 104006..104851 (+) 15595284 PA0083 (HisB1/TssB1) -
ACP00005 experimental PA0259 (tla3) T6SS00004 experimental adaptor Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 289562..291004 (-) 15595456 PA0262 (VgrG2b) PA0260 (Tle3)
ACP00006 experimental PA3906 (co-TecT) T6SS00005 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4374850..4375233 (+) 15599101 PA3905 (TecT) -
ACP00007 experimental PA3905 (tecT) T6SS00005 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4374330..4374857 (+) 15599100 PA3904 (PAAR4) PA3907 (TseT)
ACP00008 experimental PA3790 (oprC) T6SS00005 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4247703..4249874 (-) 15598985 - PA4922 (Azu)
ACP00043 experimental PA4370 (IcmP) T6SS00004 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4898193..4899533 (+) 15599566 - PA1863 (ModA)
ACP00044 experimental PA1862 (ModB) T6SS00004 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2021712..2022398 (-) 15597059 - PA1863 (ModA)
ACP00045 experimental PA1861 (ModC) T6SS00004 experimental chaperone Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2020625..2021710 (-) 15597058 - PA1863 (ModA)