Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AAYT22_RS08800 Genome accession   NZ_CP154876
Coordinates   1713331..1714155 (-) Length   274 a.a.
NCBI ID   WP_001036776.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1708331..1719155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS08795 (AAYT22_08785) - 1711709..1713040 (-) 1332 WP_000390043.1 hemolysin family protein -
  AAYT22_RS08800 (AAYT22_08790) endA 1713331..1714155 (-) 825 WP_001036776.1 DNA-entry nuclease EndA Machinery gene
  AAYT22_RS08805 (AAYT22_08795) - 1714194..1714382 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  AAYT22_RS08810 (AAYT22_08800) murA 1714375..1715658 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AAYT22_RS08815 (AAYT22_08805) - 1715682..1715912 (-) 231 WP_000250383.1 DUF1146 family protein -
  AAYT22_RS08820 (AAYT22_08810) sepM 1715970..1717007 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  AAYT22_RS08825 (AAYT22_08815) coaD 1716991..1717479 (-) 489 WP_001280723.1 pantetheine-phosphate adenylyltransferase -
  AAYT22_RS08830 (AAYT22_08820) rsmD 1717469..1718008 (-) 540 WP_000706950.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AAYT22_RS08835 (AAYT22_08825) asnA 1718073..1719065 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29908.59 Da        Isoelectric Point: 10.1089

>NTDB_id=994396 AAYT22_RS08800 WP_001036776.1 1713331..1714155(-) (endA) [Streptococcus pneumoniae strain 20155336]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=994396 AAYT22_RS08800 WP_001036776.1 1713331..1714155(-) (endA) [Streptococcus pneumoniae strain 20155336]
ATGAACAAAAAAACAAGACAGACACTGATTGGACTGCTAGTGTTATTGCTTTTGTCTGCAGGGAGCTATTATATTAAGCA
GAATGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCTCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

95.985

100

0.96
  endA Streptococcus pneumoniae D39

95.985

100

0.96
  endA Streptococcus pneumoniae R6

95.985

100

0.96
  endA Streptococcus pneumoniae TIGR4

95.985

100

0.96

Multiple sequence alignment