Detailed information NTG0993783

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EQB42_RS06215
• Genome accession: NZ_LR129841
• Coordinates: 1197271..1198119 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705304.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 947 isolate 947
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1192271..1203119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB42_RS06195	metG	1192521..1194158 (-)	1638	WP_000021543.1	methionine--tRNA ligase	-
EQB42_RS06200	-	1194226..1194900 (-)	675	WP_000903082.1	CatA-like O-acetyltransferase	-
EQB42_RS11500	-	1194959..1195258 (-)	300	WP_001138382.1	hypothetical protein	-
EQB42_RS06210	-	1195746..1196699 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
EQB42_RS06215	dprA/cilB/dalA	1197271..1198119 (-)	849	WP_000705304.1	DNA-processing protein DprA	Machinery gene
EQB42_RS06220	-	1198215..1198904 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
EQB42_RS06225	-	1198916..1199794 (-)	879	WP_000837614.1	DMT family transporter	-
EQB42_RS06230	licA	1199784..1200653 (-)	870	WP_000411218.1	choline kinase LicA	-
EQB42_RS06235	-	1200670..1201692 (-)	1023	WP_000609886.1	ribitol-5-phosphate dehydrogenase	-
EQB42_RS06240	-	1201697..1202404 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31076.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=993783 EQB42_RS06215 WP_000705304.1 1197271..1198119(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 947 isolate 947]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=993783 EQB42_RS06215 WP_000705304.1 1197271..1198119(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 947 isolate 947]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376