Detailed information NTG0993632

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR08_RS14290
• Genome accession: NZ_CP154497
• Coordinates: 2817624..2818511 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN57
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2812624..2823511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR08_RS14260 (UXR08_14260)	-	2812643..2812735 (+)	93	WP_010956583.1	hypothetical protein	-
UXR08_RS14265 (UXR08_14265)	-	2812843..2813340 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR08_RS14270 (UXR08_14270)	-	2813350..2813610 (-)	261	WP_001791974.1	hypothetical protein	-
UXR08_RS14275 (UXR08_14275)	-	2813992..2814105 (-)	114	Protein_2772	hypothetical protein	-
UXR08_RS14280 (UXR08_14280)	-	2814764..2816764 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR08_RS14285 (UXR08_14285)	-	2816761..2817516 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR08_RS14290 (UXR08_14290)	braS	2817624..2818511 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR08_RS14295 (UXR08_14295)	braR	2818522..2819187 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR08_RS14300 (UXR08_14300)	-	2819213..2819413 (-)	201	WP_000604730.1	hypothetical protein	-
UXR08_RS14305 (UXR08_14305)	-	2819611..2821035 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXR08_RS14990	-	2821095..2821196 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXR08_RS14315 (UXR08_14315)	-	2821318..2821773 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR08_RS14320 (UXR08_14320)	-	2822018..2822779 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=993632 UXR08_RS14290 WP_000143425.1 2817624..2818511(-) (braS) [Staphylococcus aureus strain BSN57]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=993632 UXR08_RS14290 WP_000143425.1 2817624..2818511(-) (braS) [Staphylococcus aureus strain BSN57]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1