Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HMPREF9425_RS02880 Genome accession   NZ_GL831112
Coordinates   545572..546216 (+) Length   214 a.a.
NCBI ID   WP_003096619.1    Uniprot ID   A0ABP2KJU0
Organism   Streptococcus vestibularis ATCC 49124     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 540572..551216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS02860 (HMPREF9425_0595) stkP/pknB 540951..542819 (+) 1869 WP_003093571.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HMPREF9425_RS02865 (HMPREF9425_0596) - 543157..543723 (+) 567 WP_003096616.1 potassium channel family protein -
  HMPREF9425_RS02870 (HMPREF9425_0597) liaF 543877..544575 (+) 699 WP_003096617.1 cell wall-active antibiotics response protein LiaF -
  HMPREF9425_RS02875 (HMPREF9425_0598) - 544572..545582 (+) 1011 WP_003093548.1 sensor histidine kinase -
  HMPREF9425_RS02880 (HMPREF9425_0599) vraR 545572..546216 (+) 645 WP_003096619.1 response regulator transcription factor Regulator
  HMPREF9425_RS02895 (HMPREF9425_0600) rimM 546892..547410 (+) 519 WP_003096621.1 ribosome maturation factor RimM -
  HMPREF9425_RS02900 (HMPREF9425_0601) trmD 547400..548119 (+) 720 WP_003094621.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HMPREF9425_RS02905 (HMPREF9425_0602) - 548121..549119 (+) 999 WP_003096623.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24005.32 Da        Isoelectric Point: 4.5762

>NTDB_id=989505 HMPREF9425_RS02880 WP_003096619.1 545572..546216(+) (vraR) [Streptococcus vestibularis ATCC 49124]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGRDGIDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAR
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=989505 HMPREF9425_RS02880 WP_003096619.1 545572..546216(+) (vraR) [Streptococcus vestibularis ATCC 49124]
ATGTCGAATAAGATTAATGTGATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTGGGAGAGGCAGGAAATGGTCGTGATGGTATCGATCTTGCTCTGGAGTTGCGTCCAGACGTTG
TTGTTATGGATCTTGTTATGCCTGAGTTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAGG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGGGCCAAAGGCTACATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGAAAGGTTTACCGTGGAGAAGAAGCTATCGAAACTGAGGTGGATA
ATAAAATTAAATATCACGATAGTCACCCGGACTTACATGATGATTTGACCGCGCGTGAACGTGATATCTTAGCCCTCTTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTGTTTATTTCTTTAAAAACCGTCAAGACCCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50

96.262

0.481
  degU Bacillus subtilis subsp. subtilis str. 168

35.455

100

0.364