Detailed information NTG0988968

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SLO00_RS14245
• Genome accession: NZ_CP152409
• Coordinates: 2803362..2804249 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN53
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2798362..2809249

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SLO00_RS14215 (SLO00_014220)	-	2798381..2798473 (+)	93	WP_010956583.1	hypothetical protein	-
SLO00_RS14220 (SLO00_014225)	-	2798581..2799078 (-)	498	WP_001065268.1	glutathione peroxidase	-
SLO00_RS14225 (SLO00_014230)	-	2799088..2799348 (-)	261	WP_001789910.1	hypothetical protein	-
SLO00_RS14230 (SLO00_014235)	-	2799730..2799843 (-)	114	WP_001791776.1	hypothetical protein	-
SLO00_RS14235 (SLO00_014240)	-	2800502..2802502 (-)	2001	WP_000776751.1	ABC transporter permease	-
SLO00_RS14240 (SLO00_014245)	-	2802499..2803254 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SLO00_RS14245 (SLO00_014250)	braS	2803362..2804249 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SLO00_RS14250 (SLO00_014255)	braR	2804260..2804925 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SLO00_RS14255 (SLO00_014260)	-	2804951..2805151 (-)	201	WP_000604728.1	hypothetical protein	-
SLO00_RS14260 (SLO00_014265)	-	2805349..2806773 (+)	1425	WP_000953744.1	alkaline phosphatase	-
SLO00_RS14265 (SLO00_014270)	-	2806843..2806953 (+)	111	WP_001791296.1	hypothetical protein	-
SLO00_RS14270 (SLO00_014275)	-	2807056..2807511 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SLO00_RS14275 (SLO00_014280)	-	2807756..2808517 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=988968 SLO00_RS14245 WP_000143419.1 2803362..2804249(-) (braS) [Staphylococcus aureus strain BSN53]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=988968 SLO00_RS14245 WP_000143419.1 2803362..2804249(-) (braS) [Staphylococcus aureus strain BSN53]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997