Detailed information NTG0983087

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ACN20J_RS22135
• Genome accession: NZ_CP183383
• Coordinates: 5032211..5033335 (+)
• Length: 374 a.a.
• NCBI ID: WP_055618634.1
• Uniprot ID: A0ABZ1HHJ8
• Organism: Streptomyces sp. 2-1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5027211..5038335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN20J_RS22120 (ACN20J_22115)	-	5027652..5028512 (+)	861	WP_307523572.1	hypothetical protein	-
ACN20J_RS22125 (ACN20J_22120)	-	5028619..5030511 (-)	1893	WP_419666595.1	BACON domain-containing protein	-
ACN20J_RS22130 (ACN20J_22125)	radA/sms	5030731..5032140 (+)	1410	WP_419666596.1	DNA repair protein RadA	Machinery gene
ACN20J_RS22135 (ACN20J_22130)	disA	5032211..5033335 (+)	1125	WP_055618634.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ACN20J_RS22140 (ACN20J_22135)	-	5033677..5034498 (-)	822	WP_361910239.1	hypothetical protein	-
ACN20J_RS22145 (ACN20J_22140)	-	5034805..5035734 (+)	930	WP_419666597.1	A/G-specific adenine glycosylase	-
ACN20J_RS22150 (ACN20J_22145)	-	5036006..5036563 (+)	558	WP_055618595.1	SigE family RNA polymerase sigma factor	-
ACN20J_RS22155 (ACN20J_22150)	-	5036593..5037201 (+)	609	WP_246575431.1	hypothetical protein	-
ACN20J_RS22160 (ACN20J_22155)	cseB	5037253..5037978 (+)	726	WP_189843137.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40267.13 Da
• Isoelectric Point: 4.9269

>NTDB_id=983087 ACN20J_RS22135 WP_055618634.1 5032211..5033335(+) (disA) [Streptomyces sp. 2-1]
MAANDRAAVPGKSAGSSGADGLMRTSLSAVAPGTGLRDGLERILRGNTGGLIVLGWDKTVEAMCSGGFVLDVEFTATRLR
ELCKLDGGIIVDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=983087 ACN20J_RS22135 WP_055618634.1 5032211..5033335(+) (disA) [Streptomyces sp. 2-1]
GTGGCAGCCAACGACCGGGCAGCAGTTCCCGGCAAGTCCGCCGGGAGTTCCGGTGCCGATGGCCTGATGCGCACCTCACT
CAGCGCCGTGGCACCCGGCACAGGGCTCCGTGACGGCCTGGAGCGCATTCTCCGCGGCAACACCGGCGGGCTCATCGTGC
TCGGCTGGGACAAGACCGTCGAGGCGATGTGCAGCGGCGGTTTCGTGCTGGACGTCGAGTTCACGGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCATCGTCGACAAGGACATCACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTGCC
CGACCCCACCATCCCCACGGAGGAGACGGGCACCCGTCACCGCACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCCGTCTCCCAGTCCATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGGCGGGTCCTGGAGGACTCGGCCGCG
ATCCTCTCCCGCGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTCGACGAGGTCGCCGGCACGTTGTC
CGCCCTCGAGATCGAGGACCTCGTCACCGTCCGGGACGTCTCGGCCGTCGCCCAGCGGCTGGAGATGGTGCGCCGGATCG
CGACCGAGATCGCCGAGTACGTGGTCGAGTTGGGCACGGACGGGCGGCTGCTCGCGCTTCAACTGGACGAGTTGATCGCC
GGGGTCGAGCCCGAGCGGGAGCTTGTCGTGCGGGACTACGTGCCCGAGCCGACCGCCAAGCGGTCGCGGACCGTCGACGA
GGCGTTGTTCGAGCTCGACGCGCTCACCCATGCGGAGCTTCTCGAACTGCCTACGGTGGCTCGGGCGTTGGGGTACACGG
GGTCGCCCGAGGCGCTCGACTCCGCGGTTTCGCCCCGCGGGTTCCGGTTGTTGGCCAAGGTGCCGCGACTGCCGGGGGCC
ATTATCGACCGGCTTGTTGAGCACTTCGGTGGGTTGCAGAAGCTGCTCGCTGCGAGTGTGGATGATCTGCAGACCGTGGA
TGGGGTGGGGGAGGCTCGGGCTCGTAGTGTGCGGGAGGGGCTTTCTCGGTTGGCTGAGTCTTCGATTCTTGAGCGGTACG
TGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.243	92.513	0.428