Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   R8566_RS04635 Genome accession   NZ_AP026920
Coordinates   915676..916326 (+) Length   216 a.a.
NCBI ID   WP_000387330.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700014     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 910676..921326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8566_RS04610 (PC0014_09200) - 910914..911414 (+) 501 WP_000566989.1 GNAT family N-acetyltransferase -
  R8566_RS04615 - 911417..911742 (+) 326 Protein_912 TfoX/Sxy family protein -
  R8566_RS04620 (PC0014_09220) - 912135..913481 (+) 1347 WP_001824784.1 IS1380-like element ISSpn5 family transposase -
  R8566_RS04625 ald 913751..914862 (-) 1112 Protein_914 alanine dehydrogenase -
  R8566_RS04630 (PC0014_09260) - 915039..915608 (+) 570 WP_000443775.1 GNAT family N-acetyltransferase -
  R8566_RS04635 (PC0014_09270) comEA/celA/cilE 915676..916326 (+) 651 WP_000387330.1 ComEA family DNA-binding protein Machinery gene
  R8566_RS04640 (PC0014_09280) comEC/celB 916310..918550 (+) 2241 WP_000942383.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  R8566_RS04645 - 918699..918916 (+) 218 Protein_918 hypothetical protein -
  R8566_RS04650 (PC0014_09290) - 918949..919536 (+) 588 WP_000939880.1 ATP-binding cassette domain-containing protein -
  R8566_RS04655 (PC0014_09300) - 919540..920715 (+) 1176 WP_000655944.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23229.65 Da        Isoelectric Point: 5.5171

>NTDB_id=97946 R8566_RS04635 WP_000387330.1 915676..916326(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700014]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=97946 R8566_RS04635 WP_000387330.1 915676..916326(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700014]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

100

100

1
  comEA/celA/cilE Streptococcus pneumoniae D39

100

100

1
  comEA/celA/cilE Streptococcus pneumoniae R6

100

100

1
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus mitis NCTC 12261

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis SK321

90.278

100

0.903
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment