Detailed information NTG0097810

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8619_RS08775
• Genome accession: NZ_AP026918
• Coordinates: 1711714..1712781 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159562.1
• Uniprot ID: B1I897
• Organism: Streptococcus pneumoniae strain PZ900700009
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1706714..1717781

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8619_RS08760 (PC0009_17290)	treR	1708511..1709221 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8619_RS08765	-	1709376..1710702 (+)	1327	Protein_1733	ISL3 family transposase	-
R8619_RS08770 (PC0009_17330)	amiF	1710777..1711703 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
R8619_RS08775 (PC0009_17340)	amiE	1711714..1712781 (-)	1068	WP_000159562.1	ABC transporter ATP-binding protein	Regulator
R8619_RS08780 (PC0009_17350)	amiD	1712790..1713716 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8619_RS08785 (PC0009_17360)	amiC	1713716..1715212 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
R8619_RS08790 (PC0009_17370)	amiA3	1715279..1717258 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=97810 R8619_RS08775 WP_000159562.1 1711714..1712781(-) (amiE) [Streptococcus pneumoniae strain PZ900700009]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKEWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=97810 R8619_RS08775 WP_000159562.1 1711714..1712781(-) (amiE) [Streptococcus pneumoniae strain PZ900700009]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGAGTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: B1I897

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538