Detailed information NTG0976997

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS37861_RS07465
• Genome accession: NZ_CP151441
• Coordinates: 1452114..1452839 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS37861
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1447114..1457839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37861_RS07430 (MGAS37861_03050)	-	1447248..1447631 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS37861_RS07435 (MGAS37861_03052)	-	1447642..1448193 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS37861_RS07440 (MGAS37861_03054)	-	1448310..1449389 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS37861_RS07450 (MGAS37861_03058)	trmB	1449587..1450222 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS37861_RS07455 (MGAS37861_03060)	ccrZ	1450222..1451013 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS37861_RS07460 (MGAS37861_03062)	-	1451077..1452111 (-)	1035	WP_010922583.1	ABC transporter permease	-
MGAS37861_RS07465 (MGAS37861_03064)	pptA	1452114..1452839 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS37861_RS07470 (MGAS37861_03066)	-	1452911..1453330 (+)	420	WP_002983376.1	HIT family protein	-
MGAS37861_RS07475 (MGAS37861_03068)	-	1453327..1453683 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS37861_RS07480 (MGAS37861_03070)	brpA	1453794..1455068 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS37861_RS07485 (MGAS37861_03072)	-	1455077..1455601 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
MGAS37861_RS07490 (MGAS37861_03074)	tsaE	1455576..1456037 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS37861_RS07495 (MGAS37861_03076)	-	1456191..1457651 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=976997 MGAS37861_RS07465 WP_002983379.1 1452114..1452839(-) (pptA) [Streptococcus pyogenes strain MGAS37861]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=976997 MGAS37861_RS07465 WP_002983379.1 1452114..1452839(-) (pptA) [Streptococcus pyogenes strain MGAS37861]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714