Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACM3H0_RS05775 Genome accession   NZ_CP180685
Coordinates   1075122..1075763 (-) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain M14     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1070122..1080763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM3H0_RS05750 (ACM3H0_05750) - 1070521..1071504 (-) 984 WP_000764455.1 sugar-binding transcriptional regulator -
  ACM3H0_RS05755 (ACM3H0_05755) - 1071623..1072378 (-) 756 WP_001080746.1 DeoR/GlpR family DNA-binding transcription regulator -
  ACM3H0_RS05760 (ACM3H0_05760) - 1072499..1073275 (+) 777 WP_000180537.1 glycyl-radical enzyme activating protein -
  ACM3H0_RS05765 (ACM3H0_05765) - 1073322..1073678 (-) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  ACM3H0_RS05770 (ACM3H0_05770) - 1073680..1075080 (-) 1401 WP_000339135.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACM3H0_RS05775 (ACM3H0_05775) vraR 1075122..1075763 (-) 642 WP_000357891.1 response regulator transcription factor Regulator
  ACM3H0_RS05780 (ACM3H0_05780) - 1075756..1076775 (-) 1020 WP_000716170.1 sensor histidine kinase -
  ACM3H0_RS05785 (ACM3H0_05785) liaF 1076772..1077467 (-) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  ACM3H0_RS05790 (ACM3H0_05790) pknB 1077626..1079581 (-) 1956 WP_000614570.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACM3H0_RS05795 (ACM3H0_05795) - 1079581..1080318 (-) 738 WP_000406231.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=976025 ACM3H0_RS05775 WP_000357891.1 1075122..1075763(-) (vraR) [Streptococcus agalactiae strain M14]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=976025 ACM3H0_RS05775 WP_000357891.1 1075122..1075763(-) (vraR) [Streptococcus agalactiae strain M14]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAGGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGACGTTGTTG
TTATGGACTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394

Multiple sequence alignment