Detailed information NTG0976025

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR11_RS14230
• Genome accession: NZ_CP151257
• Coordinates: 2811444..2812331 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN170
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2806444..2817331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR11_RS14200 (UXR11_14200)	-	2806463..2806555 (+)	93	WP_010956583.1	hypothetical protein	-
UXR11_RS14205 (UXR11_14205)	-	2806663..2807160 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR11_RS14210 (UXR11_14210)	-	2807170..2807430 (-)	261	WP_001791974.1	hypothetical protein	-
UXR11_RS14215 (UXR11_14215)	-	2807812..2807925 (-)	114	Protein_2757	hypothetical protein	-
UXR11_RS14220 (UXR11_14220)	-	2808584..2810584 (-)	2001	WP_000776750.1	ABC transporter permease	-
UXR11_RS14225 (UXR11_14225)	-	2810581..2811336 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR11_RS14230 (UXR11_14230)	braS	2811444..2812331 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR11_RS14235 (UXR11_14235)	braR	2812342..2813007 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR11_RS14240 (UXR11_14240)	-	2813033..2813233 (-)	201	WP_000604730.1	hypothetical protein	-
UXR11_RS14245 (UXR11_14245)	-	2813431..2814855 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXR11_RS14875	-	2814915..2815016 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXR11_RS14255 (UXR11_14255)	-	2815138..2815593 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR11_RS14260 (UXR11_14260)	-	2815838..2816599 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=976025 UXR11_RS14230 WP_000143425.1 2811444..2812331(-) (braS) [Staphylococcus aureus strain BSN170]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=976025 UXR11_RS14230 WP_000143425.1 2811444..2812331(-) (braS) [Staphylococcus aureus strain BSN170]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1