Detailed information NTG0972231

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC51_RS07515
• Genome accession: NZ_CP150767
• Coordinates: 1496931..1497818 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20926
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1491931..1502818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC51_RS07485 (WOC51_07475)	-	1491950..1492042 (+)	93	WP_010956583.1	hypothetical protein	-
WOC51_RS07490 (WOC51_07480)	-	1492150..1492647 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC51_RS07495 (WOC51_07485)	-	1492657..1492917 (-)	261	WP_001791974.1	hypothetical protein	-
WOC51_RS07500 (WOC51_07490)	-	1493299..1493412 (-)	114	Protein_1446	hypothetical protein	-
WOC51_RS07505 (WOC51_07495)	-	1494071..1496071 (-)	2001	WP_000776740.1	ABC transporter permease	-
WOC51_RS07510 (WOC51_07500)	-	1496068..1496823 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC51_RS07515 (WOC51_07505)	braS	1496931..1497818 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC51_RS07520 (WOC51_07510)	braR	1497829..1498494 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC51_RS07525 (WOC51_07515)	-	1498520..1498720 (-)	201	WP_000604727.1	hypothetical protein	-
WOC51_RS07530 (WOC51_07520)	-	1498918..1500342 (+)	1425	WP_000953748.1	alkaline phosphatase	-
WOC51_RS07535	-	1500402..1500503 (-)	102	WP_000731972.1	SE2200 family small protein	-
WOC51_RS07540 (WOC51_07530)	-	1500625..1501080 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC51_RS07545 (WOC51_07535)	-	1501325..1502086 (-)	762	Protein_1455	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972231 WOC51_RS07515 WP_000143417.1 1496931..1497818(-) (braS) [Staphylococcus aureus strain TUM20926]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972231 WOC51_RS07515 WP_000143417.1 1496931..1497818(-) (braS) [Staphylococcus aureus strain TUM20926]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99