Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACJWMD_RS10640 Genome accession   NZ_CP177182
Coordinates   2232874..2233617 (-) Length   247 a.a.
NCBI ID   WP_002887222.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2227874..2238617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS10625 - 2228980..2229653 (+) 674 Protein_2037 transposase -
  ACJWMD_RS10630 - 2229925..2230269 (+) 345 Protein_2038 transposase -
  ACJWMD_RS10635 - 2231557..2232864 (-) 1308 WP_002887221.1 sensor histidine kinase -
  ACJWMD_RS10640 comE/blpR 2232874..2233617 (-) 744 WP_002887222.1 response regulator transcription factor Regulator
  ACJWMD_RS10645 tnpA 2234428..2234901 (+) 474 Protein_2041 IS200/IS605 family transposase -
  ACJWMD_RS10650 - 2235146..2235376 (+) 231 WP_251981749.1 hypothetical protein -
  ACJWMD_RS10655 - 2235606..2235801 (+) 196 Protein_2043 IS30 family transposase -
  ACJWMD_RS10660 - 2236093..2237523 (+) 1431 WP_002887226.1 hypothetical protein -
  ACJWMD_RS10665 - 2237516..2238499 (+) 984 WP_002887227.1 hypothetical protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28700.12 Da        Isoelectric Point: 6.2541

>NTDB_id=969896 ACJWMD_RS10640 WP_002887222.1 2232874..2233617(-) (comE/blpR) [Streptococcus salivarius strain MRD6060]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIVKINKEEKMVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=969896 ACJWMD_RS10640 WP_002887222.1 2232874..2233617(-) (comE/blpR) [Streptococcus salivarius strain MRD6060]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATCCGAAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACGGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGACGACCGCCTATATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAATGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.975

96.761

0.522
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.431

99.595

0.393
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.652

100

0.377
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.652

100

0.377